BRPI0413024A - sistema de expressão de gene de inseto, promotor, vetor, inseto e, método para estabelecer compatibilidade de um promotor com uma espécie - Google Patents
sistema de expressão de gene de inseto, promotor, vetor, inseto e, método para estabelecer compatibilidade de um promotor com uma espécieInfo
- Publication number
- BRPI0413024A BRPI0413024A BRPI0413024-3A BRPI0413024A BRPI0413024A BR PI0413024 A BRPI0413024 A BR PI0413024A BR PI0413024 A BRPI0413024 A BR PI0413024A BR PI0413024 A BRPI0413024 A BR PI0413024A
- Authority
- BR
- Brazil
- Prior art keywords
- promoter
- insect
- species
- vector
- gene expression
- Prior art date
Links
- 241000238631 Hexapoda Species 0.000 title abstract 3
- 241000894007 species Species 0.000 title abstract 2
- 108700001097 Insect Genes Proteins 0.000 title 1
- 230000014509 gene expression Effects 0.000 title 1
- 230000001665 lethal effect Effects 0.000 abstract 1
- 230000009024 positive feedback mechanism Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001718 repressive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/60—New or modified breeds of invertebrates
- A01K67/61—Genetically modified invertebrates, e.g. transgenic or polyploid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
- A01K2227/706—Insects, e.g. Drosophila melanogaster, medfly
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/007—Vector systems having a special element relevant for transcription cell cycle specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Environmental Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Catching Or Destruction (AREA)
Abstract
"SISTEMA DE EXPRESSãO DE GENE DE INSETO, PROMOTOR, VETOR, INSETO, E, MéTODO PARA ESTABELECER COMPATIBILIDADE DE UM PROMOTOR COM UMA ESPéCIE". Promotores ativos em insetos podem ser intensificados pelos mecanismos de retroalimentação positiva e associados com efeitos letais repressivos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0317656.7 | 2003-07-28 | ||
| GB0317656A GB2404382B (en) | 2003-07-28 | 2003-07-28 | Pest control |
| PCT/GB2004/003263 WO2005012534A1 (en) | 2003-07-28 | 2004-07-28 | Expression systems for insect pest control |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0413024A true BRPI0413024A (pt) | 2006-10-03 |
| BRPI0413024B1 BRPI0413024B1 (pt) | 2018-02-27 |
Family
ID=27799347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0413024-3A BRPI0413024B1 (pt) | 2003-07-28 | 2004-07-28 | Sistema de expressão de gene reprimível, vetor, e, método para estabelecer compatibilidade de um promotor com uma espécie |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9121036B2 (pt) |
| EP (1) | EP1649027B1 (pt) |
| CN (1) | CN1860235B (pt) |
| AU (1) | AU2004261782B2 (pt) |
| BR (1) | BRPI0413024B1 (pt) |
| ES (1) | ES2447422T3 (pt) |
| GB (1) | GB2404382B (pt) |
| PT (1) | PT1649027E (pt) |
| WO (1) | WO2005012534A1 (pt) |
| ZA (1) | ZA200600728B (pt) |
Families Citing this family (37)
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| GB2355459B (en) * | 1999-11-29 | 2001-09-26 | Isis Innovation | A dominant conditional lethal genetic system |
| GB2402675B (en) * | 2003-05-12 | 2008-02-20 | Oxitec Ltd | Resistance dilution |
| GB2403475B (en) * | 2003-07-01 | 2008-02-06 | Oxitec Ltd | Stable integrands |
| GB2404382B (en) | 2003-07-28 | 2008-01-30 | Oxitec Ltd | Pest control |
| GB2443186A (en) * | 2006-10-25 | 2008-04-30 | Oxitec Ltd | Expression system for mediating alternative splicing |
| WO2007091099A1 (en) * | 2006-02-10 | 2007-08-16 | Oxitec Limited | Gene expression system using alternative splicing in insects |
| US20100077495A1 (en) * | 2006-12-21 | 2010-03-25 | Davis David P | Compositions and methods for the expression of nucleic acids |
| US9021590B2 (en) * | 2007-02-28 | 2015-04-28 | Microsoft Technology Licensing, Llc | Spyware detection mechanism |
| US20110088105A1 (en) * | 2008-03-20 | 2011-04-14 | Wimmer Ernst A | Development stage-specific lethality system for insect population control |
| KR101633477B1 (ko) * | 2008-06-12 | 2016-06-24 | 익스프레션 바이오테크놀로지스 에이피에스 | 개선된 단백질 발현계 |
| EP2364322A1 (en) * | 2008-10-28 | 2011-09-14 | Pioneer Hi-Bred International Inc. | Sulfonylurea-responsive repressor proteins |
| GB201021451D0 (en) | 2010-12-17 | 2011-02-02 | Nefila Ltd | Paralysation of silkworm larvae |
| BR112013024346A2 (pt) | 2011-03-23 | 2016-08-23 | Duong Thanh Hoang | técnica de interferência de tra-2 rna do mosquito culicinae para geneticamente produzir populações de machos |
| GB2500113A (en) | 2012-03-05 | 2013-09-11 | Oxitec Ltd | Arthropod male germline gene expression system |
| CN102943092B (zh) * | 2012-11-20 | 2014-12-10 | 西北农林科技大学 | 一种通用型PiggyBac转座子转基因载体及其制备方法 |
| WO2014089581A1 (en) * | 2012-12-05 | 2014-06-12 | Duong Thanh Hoang | A method for population replacement of culicinae mosquitoes using tra-2 rnai drivers and tta rnai repressors. |
| CN103882013B (zh) * | 2012-12-20 | 2017-05-24 | 中国科学院上海生命科学研究院 | 一种昆虫性别调控构建物,调控方法及其应用 |
| GB201303932D0 (en) | 2013-03-05 | 2013-04-17 | Oxitec Ltd | Muscle actin promoter |
| TWI507414B (zh) * | 2014-04-29 | 2015-11-11 | Nat Univ Chung Hsing | 條件式表現之重組蓖麻毒素a鍊蛋白系統 |
| GB2526867A (en) * | 2014-06-05 | 2015-12-09 | Oxitec Ltd | Gene expression system |
| US10966414B2 (en) | 2015-05-26 | 2021-04-06 | California Institute Of Technology | Population control using engineered translocations |
| KR102811061B1 (ko) | 2016-01-26 | 2025-05-21 | 세다르스-신나이 메디칼 센터 | 생체내 이중 재조합효소-매개된 카세트 교환 (dRMCE)을 위한 시스템과 방법 및 이들의 질환 모형 |
| US11098310B2 (en) | 2016-01-27 | 2021-08-24 | Just-Evotec Biologics, Inc. | Expression from transposon-based vectors and uses |
| US11261462B2 (en) | 2016-01-27 | 2022-03-01 | Just-Evotec Biologics, Inc. | Inducible expression from transposon-based vectors and uses |
| JP6937309B2 (ja) | 2016-01-27 | 2021-09-22 | ジャスト−エヴォテック バイオロジックス、インコーポレイテッド | ハイブリッドプロモーターおよびその使用 |
| US11827876B2 (en) | 2016-08-12 | 2023-11-28 | Oxitec Ltd. | Self-limiting, sex-specific gene and methods of using |
| US12157883B2 (en) | 2017-05-05 | 2024-12-03 | California Institute Of Technology | DNA sequence modification-based gene drive |
| AU2019236288B2 (en) | 2018-03-16 | 2025-06-05 | Cedars-Sinai Medical Center | Methods and compositions for inducible expression of neurotrophic factors |
| AR117409A1 (es) | 2018-03-29 | 2021-08-04 | Oxitec Ltd | Noctuidas autolimitantes |
| GB201810253D0 (en) * | 2018-06-22 | 2018-08-08 | Imperial Innovations Ltd | Gene drive |
| CN112805009A (zh) * | 2018-08-07 | 2021-05-14 | 费城儿童医院 | 基因表达的选择性剪接调控及治疗方法 |
| MX2021001708A (es) | 2018-08-14 | 2021-04-19 | Oxitec Ltd | Autoseleccion de artropodos machos esteriles. |
| US11965172B2 (en) | 2018-11-05 | 2024-04-23 | California Institute Of Technology | DNA sequence modification-based gene drive |
| AU2019418154B2 (en) | 2019-01-01 | 2026-01-22 | Geneneer Ltd | Gene expression elements and systems and use thereof |
| WO2022020196A2 (en) * | 2020-07-16 | 2022-01-27 | The Texas A&M University System | Self-eliminating transgenes |
| CN114150021B (zh) * | 2021-11-26 | 2022-10-28 | 劲帆生物医药科技(武汉)有限公司 | 一种包含重叠开放阅读框的基因的表达盒及其在昆虫细胞中的应用 |
| WO2025166032A1 (en) | 2024-02-01 | 2025-08-07 | Oxitec Limited | Self-limiting, sex-specific transgenes and methods of use |
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| US5180873A (en) | 1985-04-16 | 1993-01-19 | Dna Plant Technology Corporation | Transformation of plants to introduce closely linked markers |
| GB8901677D0 (en) | 1989-01-26 | 1989-03-15 | Ici Plc | Hybrid seed production |
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| US5254801A (en) | 1990-12-03 | 1993-10-19 | Monsanto Company | Heterologous dominant conditional lethal gene which is a phosphonate monoester hydrolase and use thereof in plants |
| GB9216151D0 (en) | 1992-07-29 | 1992-09-09 | Ici Plc | Containment of plant germplasm |
| US6225121B1 (en) * | 1992-09-14 | 2001-05-01 | Institute Of Molecular Biology And Biotechnology/Forth | Eukaryotic transposable element |
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| EG23907A (en) | 1994-08-01 | 2007-12-30 | Delta & Pine Land Co | Control of plant gene expression |
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| US5753434A (en) | 1995-02-10 | 1998-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for altering sexual behavior |
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| FR2737731B1 (fr) | 1995-08-07 | 1997-10-10 | Pasteur Institut | Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote |
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| EP0920521A1 (en) | 1996-08-26 | 1999-06-09 | Genencor International, Inc. | IDENTIFICATION OF AND CLONING A MOBILE TRANSPOSON FROM $i(ASPERGILLUS) |
| BR9711840A (pt) | 1996-10-01 | 1999-08-24 | Univ Georgia Res Found | Agentes de controle de insetos biolÄgico expressando os genes para toxinas de caro especificas para insetos m-todos e composi-{es |
| US7135608B1 (en) | 1997-08-28 | 2006-11-14 | The Salk Institute For Biological Studies | Site-specific recombination in eukaryotes and constructs useful therefor |
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| ATE532872T1 (de) * | 1999-06-01 | 2011-11-15 | Univ Utah Res Found | Methode zur expression von transgene in der keimbahn von caenorhabditis elegans |
| GB2355459B (en) | 1999-11-29 | 2001-09-26 | Isis Innovation | A dominant conditional lethal genetic system |
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| AU2001265187A1 (en) | 2000-05-30 | 2001-12-11 | Baylor College Of Medicine | Chimeric viral vectors for gene therapy |
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| ITRM20010120A1 (it) | 2001-03-08 | 2002-09-08 | Univ Napoli Federico Ii | Gene cctra come strumento per produrre progenie di soli maschi nella mosca mediterranea ceratitis capitata. |
| FR2825579B1 (fr) | 2001-06-11 | 2004-07-23 | Rhobio | Methode d'obtention de plante monocotyledone contenant un gene d'interet sans sequence auxiliaire etrangere |
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| DE10251918A1 (de) | 2002-11-08 | 2004-05-19 | Horn, Carsten, Dipl.-Biochem. Dr. | Systeme zur Erzeugung stabiler genomischer Transgen-Insertionen |
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| GB2403475B (en) | 2003-07-01 | 2008-02-06 | Oxitec Ltd | Stable integrands |
| GB2404382B (en) | 2003-07-28 | 2008-01-30 | Oxitec Ltd | Pest control |
| JP2007529223A (ja) | 2004-03-15 | 2007-10-25 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 選択的スプライシングを用いて真核細胞においてポリペプチドマルチマーを発現するための方法および構築物 |
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| WO2007091099A1 (en) | 2006-02-10 | 2007-08-16 | Oxitec Limited | Gene expression system using alternative splicing in insects |
| GB2443186A (en) | 2006-10-25 | 2008-04-30 | Oxitec Ltd | Expression system for mediating alternative splicing |
| JP2008067678A (ja) | 2006-09-15 | 2008-03-27 | Kyushu Institute Of Technology | 昆虫の減数分裂期における染色体標的組換え誘導方法 |
| CN101688246B (zh) | 2007-04-26 | 2013-09-25 | 默沙东公司 | 用于昆虫细胞的合成的表达载体 |
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-
2003
- 2003-07-28 GB GB0317656A patent/GB2404382B/en not_active Expired - Lifetime
-
2004
- 2004-07-28 BR BRPI0413024-3A patent/BRPI0413024B1/pt active IP Right Grant
- 2004-07-28 EP EP04743590.4A patent/EP1649027B1/en not_active Expired - Lifetime
- 2004-07-28 US US10/566,448 patent/US9121036B2/en not_active Expired - Lifetime
- 2004-07-28 ES ES04743590.4T patent/ES2447422T3/es not_active Expired - Lifetime
- 2004-07-28 CN CN2004800281777A patent/CN1860235B/zh not_active Expired - Fee Related
- 2004-07-28 PT PT47435904T patent/PT1649027E/pt unknown
- 2004-07-28 WO PCT/GB2004/003263 patent/WO2005012534A1/en not_active Ceased
- 2004-07-28 AU AU2004261782A patent/AU2004261782B2/en not_active Expired
-
2006
- 2006-01-25 ZA ZA200600728A patent/ZA200600728B/en unknown
- 2006-02-10 US US11/352,177 patent/US9133477B2/en active Active
-
2015
- 2015-08-28 US US14/839,683 patent/US10059961B2/en not_active Expired - Lifetime
-
2018
- 2018-07-13 US US16/035,530 patent/US10844402B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US10844402B2 (en) | 2020-11-24 |
| US10059961B2 (en) | 2018-08-28 |
| US20160060651A1 (en) | 2016-03-03 |
| US20070056051A1 (en) | 2007-03-08 |
| EP1649027A1 (en) | 2006-04-26 |
| US9121036B2 (en) | 2015-09-01 |
| US20180312870A1 (en) | 2018-11-01 |
| AU2004261782A1 (en) | 2005-02-10 |
| BRPI0413024B1 (pt) | 2018-02-27 |
| GB2404382A (en) | 2005-02-02 |
| PT1649027E (pt) | 2014-02-25 |
| GB2404382B (en) | 2008-01-30 |
| CN1860235A (zh) | 2006-11-08 |
| GB0317656D0 (en) | 2003-09-03 |
| CN1860235B (zh) | 2011-05-04 |
| WO2005012534A1 (en) | 2005-02-10 |
| ES2447422T3 (es) | 2014-03-12 |
| AU2004261782B2 (en) | 2010-04-22 |
| ZA200600728B (en) | 2007-05-30 |
| EP1649027B1 (en) | 2013-11-20 |
| US20060242717A1 (en) | 2006-10-26 |
| US9133477B2 (en) | 2015-09-15 |
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