BRPI0413360A - método e dispositivo para aumentar o fluxo de agentes transdérmicos - Google Patents
método e dispositivo para aumentar o fluxo de agentes transdérmicosInfo
- Publication number
- BRPI0413360A BRPI0413360A BRPI0413360-9A BRPI0413360A BRPI0413360A BR PI0413360 A BRPI0413360 A BR PI0413360A BR PI0413360 A BRPI0413360 A BR PI0413360A BR PI0413360 A BRPI0413360 A BR PI0413360A
- Authority
- BR
- Brazil
- Prior art keywords
- microprojection member
- increasing
- flow
- transdermal agents
- interstitial fluid
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 210000003722 extracellular fluid Anatomy 0.000 abstract 2
- 239000004744 fabric Substances 0.000 abstract 2
- 238000003780 insertion Methods 0.000 abstract 2
- 230000037431 insertion Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0064—Devices for taking samples of body liquids for taking sweat or sebum samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B2010/0009—Testing for drug or alcohol abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Prostheses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"MéTODO E DISPOSITIVO PARA AUMENTAR O FLUXO DE AGENTES TRANSDéRMICOS". Um elemento de microprojeção poroso (20, 30, 40, 50), para inserção em tecido biológico, circundado por fluido intersticial, com uma parede que inclui uma superfície interna e uma superfície externa, sendo que a superfície externa substancialmente envolve a superfície interna; e um revestimento biocompatível disposto sobre a superfície interna, sendo que o elemento de microprojeção está adaptado para restringir, substancialmente, o contato do revestimento com o tecido durante a inserção do elemento de microprojeção no tecido, sendo que o elemento de microprojeção tem porosidade suficiente para permitir a migração do fluido intersticial através da parede do elemento de microprojeção.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49261003P | 2003-08-04 | 2003-08-04 | |
| PCT/US2004/025168 WO2005016440A1 (en) | 2003-08-04 | 2004-08-03 | Method and device for enhancing transdermal agent flux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0413360A true BRPI0413360A (pt) | 2006-10-10 |
Family
ID=34193137
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0413354-4A BRPI0413354A (pt) | 2003-08-04 | 2004-08-03 | método e dispositivo para intensificar fluxo de agente transdérmico |
| BRPI0413360-9A BRPI0413360A (pt) | 2003-08-04 | 2004-08-03 | método e dispositivo para aumentar o fluxo de agentes transdérmicos |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0413354-4A BRPI0413354A (pt) | 2003-08-04 | 2004-08-03 | método e dispositivo para intensificar fluxo de agente transdérmico |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20050049549A1 (pt) |
| EP (2) | EP1656178A1 (pt) |
| JP (2) | JP2007501070A (pt) |
| KR (2) | KR20060115716A (pt) |
| CN (2) | CN1863572A (pt) |
| AR (2) | AR045205A1 (pt) |
| AU (2) | AU2004264319A1 (pt) |
| BR (2) | BRPI0413354A (pt) |
| CA (2) | CA2534823A1 (pt) |
| MX (2) | MXPA06001414A (pt) |
| SG (2) | SG130190A1 (pt) |
| TW (2) | TW200514596A (pt) |
| WO (2) | WO2005016440A1 (pt) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
| EP1523367A1 (en) | 2002-07-19 | 2005-04-20 | 3M Innovative Properties Company | Microneedle devices and microneedle delivery apparatus |
| EP1656178A1 (en) * | 2003-08-04 | 2006-05-17 | Alza Corporation | Method and device for enhancing transdermal agent flux |
| JP2007503268A (ja) * | 2003-08-25 | 2007-02-22 | スリーエム イノベイティブ プロパティズ カンパニー | 免疫応答修飾化合物の送達 |
| US20070191761A1 (en) * | 2004-02-23 | 2007-08-16 | 3M Innovative Properties Company | Method of molding for microneedle arrays |
| JP5007427B2 (ja) * | 2004-05-13 | 2012-08-22 | アルザ コーポレイション | 副甲状腺ホルモン剤の経皮送達のための装置および方法 |
| KR20070042573A (ko) * | 2004-08-11 | 2007-04-23 | 알자 코포레이션 | 나트륨 이뇨 펩티드의 경피 전달 장치 및 그 방법 |
| EP1814574A4 (en) | 2004-10-27 | 2009-08-05 | Univ Denver | ANALOGUE OF ADRENOCORTICOTROPEN HORMON AND CORRESPONDING METHODS |
| EP1827564B1 (en) * | 2004-11-18 | 2015-07-29 | 3M Innovative Properties Company | Masking method for coating a microneedle array |
| JP5015787B2 (ja) | 2004-11-18 | 2012-08-29 | スリーエム イノベイティブ プロパティズ カンパニー | マイクロニードルアレイの接触コーティング法 |
| US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
| CA2602814A1 (en) * | 2005-03-28 | 2006-10-05 | Alza Corporation | Microprojections with capillary control features and method |
| US20080195035A1 (en) * | 2005-06-24 | 2008-08-14 | Frederickson Franklyn L | Collapsible Patch and Method of Application |
| DE602006020738D1 (de) | 2005-08-01 | 2011-04-28 | Hisamitsu Pharmaceutical Co | Adjuvans oder pharmazeutische zubereitung zur transdermalen oder transmukosalen verabreichung |
| US20070078414A1 (en) * | 2005-08-05 | 2007-04-05 | Mcallister Devin V | Methods and devices for delivering agents across biological barriers |
| WO2007061781A1 (en) * | 2005-11-18 | 2007-05-31 | 3M Innovative Properties Company | Coatable compositions, coatings derived therefrom and microarrays having such coatings |
| US7658728B2 (en) * | 2006-01-10 | 2010-02-09 | Yuzhakov Vadim V | Microneedle array, patch, and applicator for transdermal drug delivery |
| EP1992386B1 (en) | 2006-02-10 | 2011-11-09 | Hisamitsu Pharmaceutical Co., Inc. | Transdermal drug administration apparatus having microneedles |
| US20090099502A1 (en) * | 2006-04-07 | 2009-04-16 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle Device And Transdermal Administration Device Provided With Microneedles |
| US7785301B2 (en) * | 2006-11-28 | 2010-08-31 | Vadim V Yuzhakov | Tissue conforming microneedle array and patch for transdermal drug delivery or biological fluid collection |
| EP2123296B1 (en) | 2007-01-31 | 2019-05-22 | Hisamitsu Pharmaceutical Co., Inc. | Adjuvant for transdermal or transmucosal administration and pharmaceutical preparation containing the same |
| AU2014200648B2 (en) * | 2007-04-16 | 2015-09-24 | Corium Pharma Solutions, Inc. | Solvent-cast microneedle arrays containing active |
| EP2146689B1 (en) * | 2007-04-16 | 2020-08-12 | Corium, Inc. | Solvent-cast microneedle arrays containing active |
| US8911749B2 (en) | 2007-04-16 | 2014-12-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
| KR20140143461A (ko) * | 2007-08-06 | 2014-12-16 | 알레간 인코포레이티드 | 데스모프레신 약물 전달을 위한 방법 및 장치 |
| WO2010006186A1 (en) * | 2008-07-09 | 2010-01-14 | Grantadler Corporation | Needle for subcutaneous port |
| EP2383013A4 (en) | 2008-12-26 | 2012-11-28 | Hisamitsu Pharmaceutical Co | MICRO NEEDLE DEVICE |
| EP2429627B1 (en) * | 2009-04-24 | 2017-06-14 | Corium International, Inc. | Methods for manufacturing microprojection arrays |
| US8834423B2 (en) | 2009-10-23 | 2014-09-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Dissolvable microneedle arrays for transdermal delivery to human skin |
| KR20120110119A (ko) * | 2009-12-16 | 2012-10-09 | 크론테크 파마 아베 | 코돈-최적화한 b형 간염바이러스 코어 항원(hbcag) |
| JP6327852B2 (ja) | 2010-05-04 | 2018-05-23 | コリウム インターナショナル, インコーポレイテッド | 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス |
| CN101961508A (zh) * | 2010-09-30 | 2011-02-02 | 浙江大学 | 一种聚电解质复合涂层的制备方法 |
| WO2012100002A1 (en) * | 2011-01-18 | 2012-07-26 | Massachusetts Institute Of Technology | Deployable barbed microneedle array and uses thereof |
| JP5876468B2 (ja) | 2011-02-25 | 2016-03-02 | 久光製薬株式会社 | 経皮または経粘膜投与のためのアジュバントおよびこれを含む医薬製剤 |
| US9457183B2 (en) | 2011-06-15 | 2016-10-04 | Tripep Ab | Injection needle and device |
| HK1209658A1 (en) * | 2012-05-01 | 2016-04-08 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Tip-loaded microneedle arrays for transdermal insertion |
| AU2013364053B2 (en) | 2012-12-21 | 2018-08-30 | Corium Pharma Solutions, Inc. | Microarray for delivery of therapeutic agent and methods of use |
| CA2903748C (en) | 2013-03-12 | 2021-11-02 | Corium International, Inc. | Microprojection applicators |
| US9962534B2 (en) | 2013-03-15 | 2018-05-08 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
| WO2014150285A2 (en) | 2013-03-15 | 2014-09-25 | Corium International, Inc. | Multiple impact microprojection applicators and methods of use |
| AU2014237279B2 (en) | 2013-03-15 | 2018-11-22 | Corium Pharma Solutions, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
| BR112015022625B1 (pt) | 2013-03-15 | 2023-01-31 | Corium, Inc | Aparelho de microestrutura para entrega de agente terapêutico |
| ES2871105T3 (es) * | 2013-07-16 | 2021-10-28 | Kindeva Drug Delivery Lp | Artículo que comprende una microaguja |
| EP3021930B1 (en) * | 2013-07-16 | 2020-10-07 | 3M Innovative Properties Company | Hollow microneedle with beveled tip |
| JP6430501B2 (ja) * | 2013-07-16 | 2018-11-28 | スリーエム イノベイティブ プロパティズ カンパニー | 斜角開口部を有する中空マイクロニードル |
| EP3042690B1 (en) * | 2013-09-06 | 2021-04-14 | Hisamitsu Pharmaceutical Co., Inc. | Micro-needle sheet |
| WO2015064710A1 (ja) | 2013-10-31 | 2015-05-07 | 久光製薬株式会社 | アジュバント組成物、これを含むアジュバント製剤、及びキット |
| EP2905047A1 (de) * | 2014-02-10 | 2015-08-12 | LTS LOHMANN Therapie-Systeme AG | Mikronadelsystem und Verfahren seiner Herstellung |
| KR102135495B1 (ko) * | 2014-02-27 | 2020-07-17 | 히사미쓰 세이야꾸 가부시키가이샤 | 마이크로 니들·시트 |
| US9138191B1 (en) * | 2014-07-09 | 2015-09-22 | Qualcomm Incorporated | Integrated circuit module with lead frame micro-needles |
| WO2016036866A1 (en) | 2014-09-04 | 2016-03-10 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
| CN106999702B (zh) | 2014-12-05 | 2020-07-10 | 久光制药株式会社 | 微针装置系统 |
| US10441768B2 (en) | 2015-03-18 | 2019-10-15 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
| JP2015192879A (ja) * | 2015-06-19 | 2015-11-05 | ニプロ株式会社 | ワクチン接種針 |
| US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
| WO2017066768A1 (en) | 2015-10-16 | 2017-04-20 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices |
| US11744889B2 (en) | 2016-01-05 | 2023-09-05 | University of Pittsburgh—of the Commonwealth System of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
| US10022436B2 (en) * | 2016-01-11 | 2018-07-17 | Verndari, Inc. | Microneedle compositions and methods of using same |
| JP6794998B2 (ja) * | 2016-02-04 | 2020-12-02 | 凸版印刷株式会社 | マイクロニードル |
| KR20180131554A (ko) * | 2016-03-01 | 2018-12-10 | 키토테크 메디컬 인코포레이티드 | 상처 봉합을 위한 마이크로 구조-기반 시스템, 장치, 및 방법 |
| JP6717638B2 (ja) * | 2016-03-31 | 2020-07-01 | 花王株式会社 | 開孔部を有する微細中空突起具の製造方法 |
| KR20170115429A (ko) * | 2016-04-07 | 2017-10-17 | 랩앤피플주식회사 | 생체분해성 금속을 이용한 마이크로 니들 |
| WO2017176069A2 (ko) * | 2016-04-07 | 2017-10-12 | 랩앤피플주식회사 | 생체흡수성 금속을 이용한 마이크로 니들 |
| CN108403617A (zh) * | 2018-02-24 | 2018-08-17 | 中山大学 | 曲安奈德可溶性微针及其制备方法 |
| KR102291392B1 (ko) * | 2018-03-30 | 2021-08-20 | 랩앤피플주식회사 | 멀티형 마이크로 니들 |
| US12233156B2 (en) | 2018-06-26 | 2025-02-25 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle device and method for producing the same |
| JP7737718B2 (ja) * | 2019-07-22 | 2025-09-11 | ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー | マイクロチャネルを有するニードルのための技術 |
| CN110664439B (zh) * | 2019-09-05 | 2021-07-27 | 华中科技大学 | 一种可提取皮肤组织液的微针及其制备方法 |
| US11986613B2 (en) | 2020-02-19 | 2024-05-21 | Kitotech Medical, Inc. | Microstructure systems and methods for pain treatment |
| JP2024501948A (ja) * | 2020-12-30 | 2024-01-17 | ジョージア テック リサーチ コーポレイション | 医療診断のための汗の誘導のための方法及びデバイス |
| WO2023159181A1 (en) | 2022-02-18 | 2023-08-24 | Kitotech Medical, Inc. | Force modulating deep skin staples and instruments |
| FR3162613A1 (fr) * | 2024-06-04 | 2025-12-05 | Anatox | Système de recueil de biomatériau et/ou de dépôt de particules sur une cible et procédé associé |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3123212A (en) * | 1964-03-03 | Multiple disposable intracutaneous injector package | ||
| USRE25637E (en) * | 1964-09-08 | Means for vaccinating | ||
| US2619962A (en) * | 1948-02-19 | 1952-12-02 | Res Foundation | Vaccination appliance |
| US2893392A (en) * | 1958-01-08 | 1959-07-07 | American Cyanamid Co | Article of manufacture for intracutaneous injections |
| US3072122A (en) * | 1959-01-15 | 1963-01-08 | Rosenthal Sol Roy | Package for transcutaneous injection |
| US3034507A (en) * | 1960-05-10 | 1962-05-15 | American Cyanamid Co | Intracutaneous injection device |
| US3221739A (en) * | 1962-03-26 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
| US3221740A (en) * | 1962-08-31 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
| US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| US3678150A (en) * | 1971-07-27 | 1972-07-18 | American Cyanamid Co | Process for improving the stability of ppd, qt and histoplasmin on tine applicators |
| BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
| US6559123B1 (en) * | 1985-04-19 | 2003-05-06 | Osi Pharmaceuticals, Inc. | Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof |
| SE8501990D0 (sv) * | 1985-04-24 | 1985-04-24 | Pharmacia Ab | Beleggningsforfarande |
| US5080646A (en) * | 1988-10-03 | 1992-01-14 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
| US5147296A (en) * | 1988-10-03 | 1992-09-15 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
| US5169382A (en) * | 1988-10-03 | 1992-12-08 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
| EP0429842B1 (en) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
| US5205023A (en) * | 1990-04-18 | 1993-04-27 | Hunter Robert M | Child-resistant buckle and buckle guard combination |
| US6586006B2 (en) * | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
| US6033582A (en) * | 1996-01-22 | 2000-03-07 | Etex Corporation | Surface modification of medical implants |
| US7184826B2 (en) * | 1996-06-18 | 2007-02-27 | Alza Corporation | Device and method for enhancing transdermal flux of agents being delivered or sampled |
| US5916524A (en) * | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
| US5741554A (en) * | 1996-07-26 | 1998-04-21 | Bio Dot, Inc. | Method of dispensing a liquid reagent |
| US5743960A (en) * | 1996-07-26 | 1998-04-28 | Bio-Dot, Inc. | Precision metered solenoid valve dispenser |
| US6918901B1 (en) * | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
| PT1037686E (pt) * | 1997-12-11 | 2005-10-31 | Alza Corp | Aparelho para potenciar o fluxo de agente transdermico |
| CN1206004C (zh) * | 1997-12-11 | 2005-06-15 | 阿尔扎有限公司 | 增强透皮物剂流量的装置 |
| WO1999029364A1 (en) * | 1997-12-11 | 1999-06-17 | Alza Corporation | Device for enhancing transdermal agent flux |
| US6091975A (en) * | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
| US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
| GB9817662D0 (en) * | 1998-08-13 | 1998-10-07 | Crocker Peter J | Substance delivery |
| DE69921489T2 (de) * | 1998-08-31 | 2005-10-27 | Johnson & Johnson Consumer Companies, Inc. | Elektrotransportvorrichtung mit klingen |
| CA2376128C (en) * | 1999-06-04 | 2009-01-06 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6256533B1 (en) * | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| US6533949B1 (en) * | 2000-08-28 | 2003-03-18 | Nanopass Ltd. | Microneedle structure and production method therefor |
| PT1341442E (pt) * | 2000-10-13 | 2005-09-30 | Alza Corp | Aplicador de impacto com um conjunto de microlaminas |
| WO2002030300A2 (en) * | 2000-10-13 | 2002-04-18 | Alza Corporation | Microprotrusion member retainer for impact applicator |
| NZ525294A (en) * | 2000-10-13 | 2005-02-25 | Alza Corp | Apparatus and method for piercing skin with microprotrusions |
| EP1333880B1 (en) * | 2000-10-26 | 2009-04-15 | Alza Corporation | Transdermal drug delivery devices having coated microprotrusions |
| WO2002074173A1 (en) * | 2001-03-16 | 2002-09-26 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
| ES2333849T3 (es) * | 2001-04-20 | 2010-03-02 | Alza Corporation | Disposicion de microsalientes que presenta un revestimiento que contiene un agente beneficioso. |
| US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
| US7429258B2 (en) * | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
| WO2003048031A2 (en) * | 2001-11-30 | 2003-06-12 | Alza Corporation | Methods and apparatuses for forming microprojection arrays |
| HUP0402605A2 (hu) * | 2001-12-20 | 2005-06-28 | Alza Corporation | Eszköz mikroszkopikus bemetszések ejtésére állat bőrszövetén |
| AU2003237185A1 (en) * | 2002-05-07 | 2003-11-11 | The Research Foundation Of State University Of New York | A method to rapidly prepare and screen formulations and compositions containing same |
| CN100464800C (zh) * | 2002-06-28 | 2009-03-04 | 阿尔扎公司 | 具有被涂覆的微突物的经皮药物传输装置 |
| AR042815A1 (es) * | 2002-12-26 | 2005-07-06 | Alza Corp | Dispositivo de suministro de agente activo que tiene miembros compuestos |
| BRPI0412029A (pt) * | 2003-06-30 | 2006-09-05 | Alza Corp | formulações para microprojeções revestidas contendo contra-ìons não-voláteis |
| EP1656178A1 (en) * | 2003-08-04 | 2006-05-17 | Alza Corporation | Method and device for enhancing transdermal agent flux |
-
2004
- 2004-08-03 EP EP04780070A patent/EP1656178A1/en not_active Withdrawn
- 2004-08-03 SG SG200700812-1A patent/SG130190A1/en unknown
- 2004-08-03 WO PCT/US2004/025168 patent/WO2005016440A1/en not_active Ceased
- 2004-08-03 AR ARP040102762A patent/AR045205A1/es not_active Application Discontinuation
- 2004-08-03 US US10/911,299 patent/US20050049549A1/en not_active Abandoned
- 2004-08-03 TW TW093123148A patent/TW200514596A/zh unknown
- 2004-08-03 CN CNA200480028968XA patent/CN1863572A/zh active Pending
- 2004-08-03 AR ARP040102763A patent/AR045206A1/es not_active Application Discontinuation
- 2004-08-03 JP JP2006522695A patent/JP2007501070A/ja not_active Withdrawn
- 2004-08-03 TW TW093123149A patent/TW200514593A/zh unknown
- 2004-08-03 JP JP2006522696A patent/JP2007501071A/ja not_active Withdrawn
- 2004-08-03 SG SG200700813-9A patent/SG130191A1/en unknown
- 2004-08-03 AU AU2004264319A patent/AU2004264319A1/en not_active Abandoned
- 2004-08-03 KR KR1020067002472A patent/KR20060115716A/ko not_active Withdrawn
- 2004-08-03 BR BRPI0413354-4A patent/BRPI0413354A/pt not_active IP Right Cessation
- 2004-08-03 BR BRPI0413360-9A patent/BRPI0413360A/pt not_active IP Right Cessation
- 2004-08-03 CA CA002534823A patent/CA2534823A1/en not_active Abandoned
- 2004-08-03 MX MXPA06001414A patent/MXPA06001414A/es unknown
- 2004-08-03 CA CA002534821A patent/CA2534821A1/en not_active Abandoned
- 2004-08-03 KR KR1020067002473A patent/KR20060115717A/ko not_active Withdrawn
- 2004-08-03 WO PCT/US2004/025169 patent/WO2005016441A1/en not_active Ceased
- 2004-08-03 EP EP04780069A patent/EP1654030A1/en not_active Withdrawn
- 2004-08-03 CN CNA2004800289533A patent/CN1863571A/zh active Pending
- 2004-08-03 MX MXPA06001409A patent/MXPA06001409A/es unknown
- 2004-08-03 US US10/910,889 patent/US20050031676A1/en not_active Abandoned
- 2004-08-03 AU AU2004264320A patent/AU2004264320A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| SG130190A1 (en) | 2007-03-20 |
| CA2534821A1 (en) | 2005-02-24 |
| EP1656178A1 (en) | 2006-05-17 |
| JP2007501070A (ja) | 2007-01-25 |
| EP1654030A1 (en) | 2006-05-10 |
| CN1863571A (zh) | 2006-11-15 |
| AR045206A1 (es) | 2005-10-19 |
| US20050049549A1 (en) | 2005-03-03 |
| KR20060115717A (ko) | 2006-11-09 |
| AR045205A1 (es) | 2005-10-19 |
| KR20060115716A (ko) | 2006-11-09 |
| AU2004264320A1 (en) | 2005-02-24 |
| JP2007501071A (ja) | 2007-01-25 |
| SG130191A1 (en) | 2007-03-20 |
| MXPA06001409A (es) | 2006-08-25 |
| CA2534823A1 (en) | 2005-02-24 |
| US20050031676A1 (en) | 2005-02-10 |
| TW200514596A (en) | 2005-05-01 |
| WO2005016441A1 (en) | 2005-02-24 |
| CN1863572A (zh) | 2006-11-15 |
| MXPA06001414A (es) | 2006-08-25 |
| WO2005016440A1 (en) | 2005-02-24 |
| TW200514593A (en) | 2005-05-01 |
| BRPI0413354A (pt) | 2006-10-10 |
| AU2004264319A1 (en) | 2005-02-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR045205A1 (es) | Dispositivo para mejorar el flujo de agentes transdermicos | |
| ES2479792T3 (es) | Dispositivo de asistencia ventricular neumático universal | |
| US10610665B2 (en) | Body cavity drainage catheter with microtextured surface | |
| ATE463202T1 (de) | Kapillarrohr-spitzen-design zur unterstützung des blutflusses | |
| DE60124917D1 (de) | Mikrovorrichtung und verfahren zur herstellung | |
| FI60814C (fi) | Intravenoes naolenhet | |
| BRPI0719015B8 (pt) | sistema extravascular para controlar exposição a um líquido | |
| BR9814465A (pt) | Cobertura de tampão de múltiplas camadas | |
| DK1420694T3 (da) | System til udtagelse af små mængder af kropsvæske | |
| CO5590878A2 (es) | Articulo absorbente | |
| DE60309454D1 (de) | Mit einem ventil versehenes gerät zur intradermalen verabreichung | |
| BR0210563A (pt) | Dispositivo médico inserìvel no corpo de um paciente humano ou veterinário, e, método de fabricação de um dispositivo médico revestido | |
| BRPI0602158A (pt) | conjunto de agulhas com batente de profundidade removìvel | |
| DE60110170D1 (de) | Injektionsnadel | |
| BR0312459A (pt) | Aparelho de eletroporação, aparelho para injetar um fluido no tecido corpóreo, método de eletroporação, método para injetar um fluido no tecido corpóreo, dispositivo de eletroporação, método de tratamento eletroporético de um humano ou animal não-humano, dispositivo para uso em eletroporação, e, método para determinar quando uma agulha foi inserida a uma profundidade desejada no tecido corpóreo | |
| BRPI0709672B8 (pt) | implante ocular insersível em um lúmen ocular e método de distribuição de um agente terapêutico a um olho | |
| BRPI0413532A (pt) | dispositivo de infusão tipo remendo | |
| ATE434458T1 (de) | Austragungsvorrichtungen für eine lokal begrenzte austragung eines pleurodesewirkstoffes | |
| BR0214411A (pt) | Artigo descartável próprio para ser usado dotado de um elemento de sensação de umidade | |
| ATE263591T1 (de) | Mikroperfusionsvorrichtung | |
| NO992029D0 (no) | Katetersammenstilling med et bruksklart kateter | |
| ATE516763T1 (de) | Katheter für thermotherapie | |
| WO2008013881A3 (en) | Methods and materials for stabilizing analyte sensors | |
| SE9801405D0 (sv) | Implant | |
| DE60037657D1 (de) | Infektionsmittel enthaltendes medizinisches gerät und verfahren zu ihrer darstellung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |