BRPI0414311A - formas de dosagem de liberação controlada - Google Patents
formas de dosagem de liberação controladaInfo
- Publication number
- BRPI0414311A BRPI0414311A BRPI0414311-6A BRPI0414311A BRPI0414311A BR PI0414311 A BRPI0414311 A BR PI0414311A BR PI0414311 A BRPI0414311 A BR PI0414311A BR PI0414311 A BRPI0414311 A BR PI0414311A
- Authority
- BR
- Brazil
- Prior art keywords
- drug
- present
- formula
- release
- provides
- Prior art date
Links
- 238000013270 controlled release Methods 0.000 title abstract 4
- 239000002552 dosage form Substances 0.000 title abstract 3
- 239000003814 drug Substances 0.000 abstract 16
- 229940079593 drug Drugs 0.000 abstract 16
- 210000001072 colon Anatomy 0.000 abstract 6
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 1
- 208000011231 Crohn disease Diseases 0.000 abstract 1
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 1
- 238000007906 compression Methods 0.000 abstract 1
- 230000006835 compression Effects 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 230000037406 food intake Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 1
- 210000003750 lower gastrointestinal tract Anatomy 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
- 230000000541 pulsatile effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
FORMAS DE DOSAGEM DE LIBERAçãO CONTROLADA. A presente invenção se relaciona a uma forma de dosagem para administração oral que preferencialmente libera a droga no o cólon. A presente invenção é adicionalmentemente relacionada a métodos de preparar tais formulações, e métodos de tratamento utilizando tais formulações. é um objeto da presente invenção prover uma fórmula de dosagem farmacêutica oral que formar que preveja o atraso da liberação da(s) droga(s) no cólon de um ser humano depois de ingestão oral da fórmula dosada. é um objeto adicionalmentemente de certas incorporações da presente invenção prover uma fórmula de dosagem farmacêutica oral que provê um atraso para liberar demora liberar uma(s) droga(s) na área gastrintestinal de um ser humano como isso a droga é liberada no cólon. é um objeto adicionalmentemente de certas incorporações da presente invenção para prover uma fórmula de dosagem farmacêutica tendo um núcleo contendo droga, o núcleo sendo comprimido e coberto com uma coberta com uma camada que provê um atraso para liberar a fórmula de dosagem depois da dosagem ser oralmente administrada para um ser humano. é um objeto adicionalmentemente de certas incorporações da presente invenção para prover uma fórmula de dosagem farmacêutica oral tendo uma droga contenda um núcleo que é comprimida e coberta com uma camada que provê um atraso para liberar a droga quando a fórmula de dosagem for oralmente administrado em um ser humano. é um objeto adicionalmentemente de certas incorporações da presente invenção para prover uma fórmula que permite a dosagem para especificamente o cólon atuando para uma larga variedade de doenças. é um objeto adicionalmentemente de certas Incorporações da presente invenção para prover dosagem forma atuando em doenças como colite ulcerativa, Doença do Crohn ou outras doenças que são tipicamente mais sintomáticas em área gastrintestinal inferior. é um objeto adicionalmentemente de certas incorporações da presente invenção para prover uma fórmula de dosagem que prevê um atraso para liberar a droga da fórmula de dosagem tal que a droga é liberada no cólon, seguido por um liberação controlada da droga depois disso. é um objeto adicionalmentemente de certas incorporações da presente invenção prover uma compressão da cobertura da fórmula de dosagem tendo uma imediata liberação da camada de uma(s) droga(s) com uma sobre cobertura sobre o núcleo comprimido que prevê um atraso para liberar a mesma droga ou diferente(s) da fórmula de dosagem; o núcleo opcionalmente provendo um liberação controlada da droga depois disso. é um objeto adicionalmentemente de certas incorporações da presente invenção prover uma fórmula de dosagem oral que provê um local de liberação específico de droga (P,.ex., para o cólon). é um objeto adicionalmentemente de certas incorporações da presente invenção para desenvolver uma fórmula de dosagem oral que prevê liberação programada da droga. é um objeto adicionalmentemente de certas incorporações da presente invenção para desenvolver uma fórmula de dosagem oral que prevê a liberação pulsativa da droga.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50403503P | 2003-09-19 | 2003-09-19 | |
| PCT/US2004/030450 WO2005027878A1 (en) | 2003-09-19 | 2004-09-17 | Delayed released dosage forms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0414311A true BRPI0414311A (pt) | 2008-03-04 |
Family
ID=34375438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0414311-6A BRPI0414311A (pt) | 2003-09-19 | 2004-09-17 | formas de dosagem de liberação controlada |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8389008B2 (pt) |
| EP (1) | EP1670442A4 (pt) |
| JP (1) | JP2007505921A (pt) |
| KR (1) | KR100782918B1 (pt) |
| CN (1) | CN1882316A (pt) |
| AP (1) | AP2006003585A0 (pt) |
| BR (1) | BRPI0414311A (pt) |
| CA (1) | CA2539051C (pt) |
| EA (1) | EA200600598A1 (pt) |
| IL (1) | IL174343A0 (pt) |
| MX (1) | MXPA06003100A (pt) |
| NZ (1) | NZ545921A (pt) |
| WO (1) | WO2005027878A1 (pt) |
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| EP1429744A1 (en) | 2001-09-21 | 2004-06-23 | Egalet A/S | Morphine polymer release system |
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-
2004
- 2004-09-17 US US10/943,356 patent/US8389008B2/en not_active Expired - Lifetime
- 2004-09-17 CA CA2539051A patent/CA2539051C/en not_active Expired - Fee Related
- 2004-09-17 BR BRPI0414311-6A patent/BRPI0414311A/pt not_active Application Discontinuation
- 2004-09-17 EP EP04784340A patent/EP1670442A4/en not_active Withdrawn
- 2004-09-17 JP JP2006527046A patent/JP2007505921A/ja active Pending
- 2004-09-17 NZ NZ545921A patent/NZ545921A/en unknown
- 2004-09-17 AP AP2006003585A patent/AP2006003585A0/xx unknown
- 2004-09-17 KR KR1020067005515A patent/KR100782918B1/ko not_active Expired - Fee Related
- 2004-09-17 WO PCT/US2004/030450 patent/WO2005027878A1/en not_active Ceased
- 2004-09-17 EA EA200600598A patent/EA200600598A1/ru unknown
- 2004-09-17 CN CNA2004800342677A patent/CN1882316A/zh active Pending
- 2004-09-17 MX MXPA06003100A patent/MXPA06003100A/es active IP Right Grant
-
2006
- 2006-03-16 IL IL174343A patent/IL174343A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2539051A1 (en) | 2005-03-31 |
| AU2004273956A1 (en) | 2005-03-31 |
| NZ545921A (en) | 2009-09-25 |
| WO2005027878A1 (en) | 2005-03-31 |
| CA2539051C (en) | 2014-08-12 |
| KR100782918B1 (ko) | 2007-12-07 |
| KR20060070565A (ko) | 2006-06-23 |
| EP1670442A1 (en) | 2006-06-21 |
| EA200600598A1 (ru) | 2006-08-25 |
| JP2007505921A (ja) | 2007-03-15 |
| US8389008B2 (en) | 2013-03-05 |
| MXPA06003100A (es) | 2006-06-20 |
| AP2006003585A0 (en) | 2006-04-30 |
| EP1670442A4 (en) | 2011-09-14 |
| CN1882316A (zh) | 2006-12-20 |
| IL174343A0 (en) | 2009-02-11 |
| US20050112201A1 (en) | 2005-05-26 |
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