BRPI0414699A - formulações de acetato de anecortave e acetonida de triancinolona para injeção - Google Patents
formulações de acetato de anecortave e acetonida de triancinolona para injeçãoInfo
- Publication number
- BRPI0414699A BRPI0414699A BRPI0414699-9A BRPI0414699A BRPI0414699A BR PI0414699 A BRPI0414699 A BR PI0414699A BR PI0414699 A BRPI0414699 A BR PI0414699A BR PI0414699 A BRPI0414699 A BR PI0414699A
- Authority
- BR
- Brazil
- Prior art keywords
- injection
- triamcinolone acetonide
- anecortave acetate
- formulations
- acetonide formulations
- Prior art date
Links
- 238000002347 injection Methods 0.000 title abstract 3
- 239000007924 injection Substances 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- YUWPMEXLKGOSBF-GACAOOTBSA-N Anecortave acetate Chemical compound O=C1CC[C@]2(C)C3=CC[C@]4(C)[C@](C(=O)COC(=O)C)(O)CC[C@H]4[C@@H]3CCC2=C1 YUWPMEXLKGOSBF-GACAOOTBSA-N 0.000 title abstract 2
- 229960001232 anecortave Drugs 0.000 title abstract 2
- 229960002117 triamcinolone acetonide Drugs 0.000 title abstract 2
- YNDXUCZADRHECN-JNQJZLCISA-N triamcinolone acetonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O YNDXUCZADRHECN-JNQJZLCISA-N 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"FORMULAçõES DE ACETATO DE ANECORTAVE E ACETONIDA DE TRIANCINOLONA PARA INJEçãO". A presente invenção refere-se a composições injetáveis de acetonida de triancinolona ou acetato de anecortave. As composições são particularmente adequadas para injeção no segmento posterior do olho para tratar doenças oftálmicas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50538603P | 2003-09-23 | 2003-09-23 | |
| PCT/US2004/028598 WO2005032510A1 (en) | 2003-09-23 | 2004-09-02 | Triamcinolone acetonide and anecortave acetate formulations for injection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0414699A true BRPI0414699A (pt) | 2006-11-28 |
Family
ID=34421523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0414699-9A BRPI0414699A (pt) | 2003-09-23 | 2004-09-02 | formulações de acetato de anecortave e acetonida de triancinolona para injeção |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20050065137A1 (pt) |
| EP (1) | EP1663144A1 (pt) |
| JP (1) | JP2007506678A (pt) |
| KR (1) | KR20060095974A (pt) |
| CN (1) | CN1852700A (pt) |
| AR (1) | AR045943A1 (pt) |
| AU (1) | AU2004277864A1 (pt) |
| BR (1) | BRPI0414699A (pt) |
| CA (1) | CA2539023A1 (pt) |
| MX (1) | MXPA06003185A (pt) |
| RU (1) | RU2006113593A (pt) |
| TW (1) | TW200518760A (pt) |
| WO (1) | WO2005032510A1 (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070224278A1 (en) | 2003-11-12 | 2007-09-27 | Lyons Robert T | Low immunogenicity corticosteroid compositions |
| US20050250737A1 (en) * | 2003-11-12 | 2005-11-10 | Allergan, Inc. | Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods |
| US20050101582A1 (en) * | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
| US20060094700A1 (en) * | 2004-11-02 | 2006-05-04 | Allergan, Inc. | Heat sterilization of a steroid in the presence of phosphate |
| ITRM20050547A1 (it) * | 2005-11-04 | 2007-05-05 | Sooft Italia S R L | Gel oftalmico composto da triamcinolone acetonide e da un polimero poliacrilico. |
| US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
| US9161970B2 (en) | 2007-12-12 | 2015-10-20 | Allergan, Inc. | Dermal filler |
| SI2262506T1 (sl) * | 2008-03-11 | 2014-07-31 | Alcon Research, Ltd. | Močno flokulirane suspenzije triamcinolon acetonida z nizko viskoznostjo za intravitrealno injekcijo |
| TWI580441B (zh) * | 2008-09-19 | 2017-05-01 | 愛爾康研究有限公司 | 穩定的藥學次微米懸浮液及其形成方法 |
| CN101893619B (zh) * | 2010-02-10 | 2013-11-13 | 上海蓝怡科技有限公司 | 改进乳胶悬浊液稳定性的方法 |
| WO2012051575A2 (en) | 2010-10-15 | 2012-04-19 | Iscience Interventional Corporation | Device for ocular access |
| SG11201503637SA (en) * | 2012-11-08 | 2015-06-29 | Clearside Biomedical Inc | Methods and devices for the treatment of ocular diseases in human subjects |
| KR102282973B1 (ko) | 2013-05-03 | 2021-07-27 | 클리어사이드 바이오메디컬, 인코포레이드 | 안구용 주사를 위한 장치 및 방법 |
| WO2014197317A1 (en) | 2013-06-03 | 2014-12-11 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
| RU2710491C2 (ru) | 2014-06-20 | 2019-12-26 | Клиасайд Байомедикал, Инк. | Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань |
| USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
| US10390901B2 (en) | 2016-02-10 | 2019-08-27 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
| WO2017192565A1 (en) | 2016-05-02 | 2017-11-09 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
| IL264764B2 (en) | 2016-08-12 | 2024-02-01 | Clearside Biomedical Inc | Devices and methods for adjusting the insertion depth of a drug administration needle |
| WO2018204515A1 (en) | 2017-05-02 | 2018-11-08 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
| AU2019207515B2 (en) * | 2018-01-10 | 2024-11-14 | Eye Co Pty Ltd | Medical device and pharmaceutical composition for treatment of an eye disease or condition |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4975537A (en) * | 1985-10-23 | 1990-12-04 | The Upjohn Company | Δ9(11) -angiostatic steroids |
| US4771042A (en) * | 1985-11-25 | 1988-09-13 | The Upjohn Company | Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments |
| US5407926A (en) * | 1987-12-29 | 1995-04-18 | Alcon Laboratories, Inc. | Ophthalmic composition |
| US4876250A (en) * | 1988-10-31 | 1989-10-24 | Alcon Laboratories, Inc. | Methods for controlling ocular hypertension with angiostatic steroids |
| US5192535A (en) * | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
| US5972922A (en) * | 1990-06-11 | 1999-10-26 | Alcon Laboratories, Inc. | Steroids which inhibit angiogenesis |
| US5770592A (en) * | 1991-11-22 | 1998-06-23 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization using angiostatic steroids |
| US5679666A (en) * | 1991-11-22 | 1997-10-21 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization by treatment with angiostatic steroids |
| US5474985A (en) * | 1993-12-22 | 1995-12-12 | The Regents Of The University Of California | Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors |
| US6172054B1 (en) * | 1995-06-15 | 2001-01-09 | Alcon Laboratories, Inc. | Combination therapy for lowering and controlling intraocular pressure |
| CA2289618A1 (en) * | 1997-05-14 | 1998-11-19 | Shin-Ichi Yasueda | Aqueous suspension preparations with excellent redispersibility |
| US6011023A (en) * | 1997-08-27 | 2000-01-04 | Alcon Laboratories, Inc. | Angiostatic steroids |
| US6428814B1 (en) * | 1999-10-08 | 2002-08-06 | Elan Pharma International Ltd. | Bioadhesive nanoparticulate compositions having cationic surface stabilizers |
| ATE401908T1 (de) * | 1999-04-09 | 2008-08-15 | Ortho Mcneil Pharm Inc | Pharmazeutische zusammensetzungen von erythropoietin |
| US6696426B2 (en) * | 2000-08-22 | 2004-02-24 | Pharmacia Corporation | Preservative free ophthalmic oxazolidinone antibiotic drug delivery systems |
| AU2001278779A1 (en) * | 2000-08-25 | 2002-03-04 | Senju Pharmaceutical Co. Ltd. | Aqueous suspension preparations |
| AU2002243760A1 (en) * | 2001-01-30 | 2002-08-12 | Board Of Regents University Of Texas System | Process for production of nanoparticles and microparticles by spray freezing into liquid |
| US20030129242A1 (en) * | 2002-01-04 | 2003-07-10 | Bosch H. William | Sterile filtered nanoparticulate formulations of budesonide and beclomethasone having tyloxapol as a surface stabilizer |
| EP1539182A4 (en) * | 2002-08-05 | 2010-01-20 | Alcon Inc | USE OF ANECORTAVEACETATE FOR THE PROTECTION OF THE SEVERING POWER OF PATIENTS WITH AGE-RELATED MACULAR AGENCY |
| US20060154910A1 (en) * | 2003-02-20 | 2006-07-13 | Bingaman David P | Use of steroids to treat ocular disorders |
| AU2004212900A1 (en) * | 2003-02-20 | 2004-09-02 | Alcon, Inc. | Formulations of glucocorticoids to treat pathologic ocular angiogenesis |
| US20040186084A1 (en) * | 2003-03-21 | 2004-09-23 | Akorn, Inc. | Triamcinolone formulations and methods for their preparation and use |
-
2004
- 2004-09-02 RU RU2006113593/15A patent/RU2006113593A/ru not_active Application Discontinuation
- 2004-09-02 EP EP04782985A patent/EP1663144A1/en not_active Withdrawn
- 2004-09-02 BR BRPI0414699-9A patent/BRPI0414699A/pt not_active IP Right Cessation
- 2004-09-02 KR KR1020067005546A patent/KR20060095974A/ko not_active Withdrawn
- 2004-09-02 JP JP2006526921A patent/JP2007506678A/ja not_active Withdrawn
- 2004-09-02 CA CA002539023A patent/CA2539023A1/en not_active Abandoned
- 2004-09-02 US US10/933,006 patent/US20050065137A1/en not_active Abandoned
- 2004-09-02 CN CNA2004800264396A patent/CN1852700A/zh active Pending
- 2004-09-02 MX MXPA06003185A patent/MXPA06003185A/es not_active Application Discontinuation
- 2004-09-02 AU AU2004277864A patent/AU2004277864A1/en not_active Abandoned
- 2004-09-02 WO PCT/US2004/028598 patent/WO2005032510A1/en not_active Ceased
- 2004-09-13 TW TW093127639A patent/TW200518760A/zh unknown
- 2004-09-22 AR ARP040103418A patent/AR045943A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005032510A1 (en) | 2005-04-14 |
| CA2539023A1 (en) | 2005-04-14 |
| CN1852700A (zh) | 2006-10-25 |
| MXPA06003185A (es) | 2006-06-23 |
| EP1663144A1 (en) | 2006-06-07 |
| AR045943A1 (es) | 2005-11-16 |
| TW200518760A (en) | 2005-06-16 |
| US20050065137A1 (en) | 2005-03-24 |
| KR20060095974A (ko) | 2006-09-05 |
| RU2006113593A (ru) | 2006-08-27 |
| AU2004277864A1 (en) | 2005-04-14 |
| JP2007506678A (ja) | 2007-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A,5A, 6A E 7A ANUIDADE(S) |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011. |