BRPI0415242B8 - microgrânulos de liberação gradual contendo extrato de gingko biloba e o processo para fabricar estes - Google Patents

microgrânulos de liberação gradual contendo extrato de gingko biloba e o processo para fabricar estes

Info

Publication number
BRPI0415242B8
BRPI0415242B8 BRPI0415242A BRPI0415242A BRPI0415242B8 BR PI0415242 B8 BRPI0415242 B8 BR PI0415242B8 BR PI0415242 A BRPI0415242 A BR PI0415242A BR PI0415242 A BRPI0415242 A BR PI0415242A BR PI0415242 B8 BRPI0415242 B8 BR PI0415242B8
Authority
BR
Brazil
Prior art keywords
ginkgo biloba
making
biloba extract
containing ginkgo
microgranules containing
Prior art date
Application number
BRPI0415242A
Other languages
English (en)
Inventor
Marechal Dominique
Yang Wei-Hong
Hu Yu-Zhang
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Publication of BRPI0415242A publication Critical patent/BRPI0415242A/pt
Publication of BRPI0415242B1 publication Critical patent/BRPI0415242B1/pt
Publication of BRPI0415242B8 publication Critical patent/BRPI0415242B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)

Abstract

"microgranulos de liberação gradual contendo extrato de gingko biloba e o processo para fabricar estes". a presente invenção refere-se a uma nova formulação de fármaco herbal estável sob a forma de microgrânulos de liberação gradual contendo extrato de gingko biloba bem como o processo para fabricar esta.
BRPI0415242A 2003-10-10 2004-10-11 microgrânulos de liberação gradual contendo extrato de gingko biloba e o processo para fabricar estes BRPI0415242B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03292512 2003-10-10
EP03292512.5 2003-10-10
PCT/IB2004/003542 WO2005034923A1 (en) 2003-10-10 2004-10-11 Sustained-release microgranules containing gingko biloba extract and the process for manufacturing these

Publications (3)

Publication Number Publication Date
BRPI0415242A BRPI0415242A (pt) 2006-12-12
BRPI0415242B1 BRPI0415242B1 (pt) 2017-06-27
BRPI0415242B8 true BRPI0415242B8 (pt) 2021-05-25

Family

ID=34429540

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415242A BRPI0415242B8 (pt) 2003-10-10 2004-10-11 microgrânulos de liberação gradual contendo extrato de gingko biloba e o processo para fabricar estes

Country Status (9)

Country Link
US (1) US7569236B2 (pt)
EP (1) EP1689373B1 (pt)
JP (1) JP5171038B2 (pt)
KR (1) KR101148734B1 (pt)
CN (1) CN1874764B (pt)
BR (1) BRPI0415242B8 (pt)
CA (1) CA2541578C (pt)
MX (1) MXPA06003942A (pt)
WO (1) WO2005034923A1 (pt)

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MXPA03003895A (es) 2000-10-30 2003-07-28 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada.
JP2007254339A (ja) * 2006-03-22 2007-10-04 Takasago Internatl Corp ロックイン型粉末
FR2938430B1 (fr) * 2008-11-14 2011-05-20 Debregeas Et Associes Pharma Granules a base de plantes
CA2798702A1 (en) 2010-05-11 2011-11-17 Cima Labs Inc. Alcoholresistant metoprolol-containing extended-release oral dosage forms
NZ603531A (en) * 2010-05-11 2014-08-29 Cima Labs Inc Alcohol-resistant formulations
CH704253A1 (de) * 2010-12-21 2012-06-29 Mepha Gmbh Pharmazeutische Zusammensetzung enthaltend pflanzliche Wirkstoffe.
CN105435236A (zh) * 2015-12-04 2016-03-30 中国林业科学研究院林产化学工业研究所 一种银杏抗性淀粉微球的制备方法
WO2017146286A1 (ko) * 2016-02-26 2017-08-31 에스케이케미칼주식회사 친수성서방폴리머의 매트릭스를 이용한 은행잎 추출물의 약학조성물 및 이를 이용한 경구용 서방성 제제
KR101992394B1 (ko) 2016-03-07 2019-06-24 에스케이케미칼 주식회사 친수성서방폴리머의 매트릭스를 이용한 은행잎 추출물의 약학조성물 및 이를 이용한 경구용 서방성 제제
KR101992404B1 (ko) 2016-03-07 2019-06-24 에스케이케미칼 주식회사 친수성서방폴리머의 매트릭스를 이용한 은행잎 추출물의 약학조성물 및 이를 이용한 경구용 서방성 제제
AU2021292406B2 (en) 2020-06-18 2024-03-14 XWPharma Ltd. Controlled release granulations of water-soluble active pharmaceutical ingredients
CN115803017A (zh) * 2020-06-18 2023-03-14 凯瑞康宁生物工程有限公司 水溶性活性药物成分的药物造粒物
KR20230058151A (ko) 2020-10-05 2023-05-02 엑스더블유파마 리미티드 감마-하이드록시부티르산 유도체의 변형된 방출 조성물
EP4588471A3 (en) 2021-03-19 2025-09-24 XWPharma Ltd. Pharmacokinetics of combined release formulations of a gamma-hydroxybutyric acid derivative

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Also Published As

Publication number Publication date
BRPI0415242B1 (pt) 2017-06-27
WO2005034923A1 (en) 2005-04-21
EP1689373A1 (en) 2006-08-16
KR20060115869A (ko) 2006-11-10
MXPA06003942A (es) 2006-07-05
EP1689373B1 (en) 2019-04-03
CN1874764A (zh) 2006-12-06
CA2541578A1 (en) 2005-04-21
KR101148734B1 (ko) 2012-07-05
US7569236B2 (en) 2009-08-04
JP5171038B2 (ja) 2013-03-27
CN1874764B (zh) 2012-08-01
BRPI0415242A (pt) 2006-12-12
JP2007508292A (ja) 2007-04-05
US20070009598A1 (en) 2007-01-11
CA2541578C (en) 2014-03-25

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2849 DE 12-08-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.