BRPI0415496A - microdisposição de oligonucleotìdeo - Google Patents

microdisposição de oligonucleotìdeo

Info

Publication number
BRPI0415496A
BRPI0415496A BRPI0415496-7A BRPI0415496A BRPI0415496A BR PI0415496 A BRPI0415496 A BR PI0415496A BR PI0415496 A BRPI0415496 A BR PI0415496A BR PI0415496 A BRPI0415496 A BR PI0415496A
Authority
BR
Brazil
Prior art keywords
oligonucleotide
microdevisions
microdisposition
oligonucleotides
specifically
Prior art date
Application number
BRPI0415496-7A
Other languages
English (en)
Inventor
Jan Weiler
Jonathan Hall
Christoph Wanke
J Rg Bernd Lange
Witold Filipowicz
Fabrice Kolb
Original Assignee
Novartis Ag
Novartis Forschungsstiftung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Novartis Forschungsstiftung filed Critical Novartis Ag
Publication of BRPI0415496A publication Critical patent/BRPI0415496A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

"MICRODISPOSIçãO DE OLIGONUCLEOTìDEO". A presente invenção refere-se a microdisposições de oligonucleotídeo compreendendo oligonucleotídeos de RNA quimicamente modificados curtos e usos de tais microdisposições em aplicações genómicas. Mais especificamente, a invenção provê uma disposição de oligonucleotídeo compreendendo uma superfície e uma pluralidade de oligonucleotídeos, onde pelo menos um oligonucleotídeo tem pelo menos uma porção açúcar modificada na posição 2<39>OH. As microdisposições da invenção são mais especificamente úteis para detectar RNAs pequenos.
BRPI0415496-7A 2003-10-14 2004-10-13 microdisposição de oligonucleotìdeo BRPI0415496A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51088403P 2003-10-14 2003-10-14
PCT/EP2004/011511 WO2005040419A1 (en) 2003-10-14 2004-10-13 Oligonucleotide microarray

Publications (1)

Publication Number Publication Date
BRPI0415496A true BRPI0415496A (pt) 2006-12-26

Family

ID=34520022

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415496-7A BRPI0415496A (pt) 2003-10-14 2004-10-13 microdisposição de oligonucleotìdeo

Country Status (9)

Country Link
US (1) US20080045417A1 (pt)
EP (1) EP1675965A1 (pt)
JP (1) JP2007512805A (pt)
CN (1) CN1867680A (pt)
AU (2) AU2004284178A1 (pt)
BR (1) BRPI0415496A (pt)
CA (1) CA2539654A1 (pt)
MX (1) MXPA06004103A (pt)
WO (1) WO2005040419A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040219565A1 (en) 2002-10-21 2004-11-04 Sakari Kauppinen Oligonucleotides useful for detecting and analyzing nucleic acids of interest
ATE546528T1 (de) 2002-11-13 2012-03-15 Univ Jefferson Zusammensetzungen und verfahren zur diagnose und behandlung von krebs
DK1735459T3 (da) * 2004-04-07 2012-05-29 Exiqon As Fremgangsmåder til kvantificering af microRNA'er og små interfererende RNA'er
US8192937B2 (en) 2004-04-07 2012-06-05 Exiqon A/S Methods for quantification of microRNAs and small interfering RNAs
WO2007044057A2 (en) 2005-02-24 2007-04-19 The Ohio State University Research Foundation Methods for quantifying microrna precursors
US8592384B2 (en) 2005-04-04 2013-11-26 The Board Of Regents Of The University Of Texas System Micro-RNA's that regulate muscle cells
US7919239B2 (en) * 2005-07-01 2011-04-05 Agilent Technologies, Inc. Increasing hybridization efficiencies
US7955848B2 (en) 2006-04-03 2011-06-07 Trustees Of Dartmouth College MicroRNA biomarkers for human breast and lung cancer
US8207325B2 (en) 2006-04-03 2012-06-26 Univ. of Copenhagen MicroRNA biomarkers for human breast and lung cancer
DK2182969T3 (en) 2007-07-31 2017-02-27 Univ Texas Micro-RNA family that modulates fibrosis and its applications
CN101424640B (zh) * 2007-11-02 2012-07-25 江苏命码生物科技有限公司 血清中微小核糖核酸的检测方法和用于检测的试剂盒、生物芯片及其制作和应用方法
WO2009062169A2 (en) 2007-11-09 2009-05-14 The Board Of Regents Of The University Of Texas System Micro-rnas of the mir-15 family modulate cardiomyocyte survival and cardiac repair
EP2520649A3 (en) * 2007-11-23 2013-02-20 Panagene, Inc. MicroRNA antisense PNAs, compositions comprising the same, and methods for using and evaluating the same
WO2009117418A2 (en) 2008-03-17 2009-09-24 The Board Of Regents Of The University Of Texas System Identification of micro-rnas involved in neuromuscular synapse maintenance and regeneration
US9163235B2 (en) 2012-06-21 2015-10-20 MiRagen Therapeutics, Inc. Inhibitors of the miR-15 family of micro-RNAs
CA3031071A1 (en) * 2016-07-18 2018-01-25 Jaan Biotherapeutics, Llc Compositions and methods for treatment of cardiac diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5269600A (en) * 1999-05-13 2000-12-05 Oligos Etc. Inc. Arrays with modified oligonucleotide and polynucleotide compositions
JP4230457B2 (ja) * 2002-12-18 2009-02-25 サード・ウェーブ・テクノロジーズ・インク 低分子核酸の検出方法
WO2005003318A2 (en) * 2003-07-02 2005-01-13 Perkinelmer Las, Inc. Assay and process for labeling and detection of micro rna and small interfering rna sequences

Also Published As

Publication number Publication date
JP2007512805A (ja) 2007-05-24
AU2004284178A1 (en) 2005-05-06
EP1675965A1 (en) 2006-07-05
US20080045417A1 (en) 2008-02-21
MXPA06004103A (es) 2006-06-27
WO2005040419A1 (en) 2005-05-06
CN1867680A (zh) 2006-11-22
CA2539654A1 (en) 2005-05-06
AU2008207515A1 (en) 2008-09-18
WO2005040419A8 (en) 2006-05-11

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A E 6AANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2112 DE 28/06/2011.