BRPI0416591A - métodos e reagentes para o tratamento de distúrbios inflamatórios - Google Patents

métodos e reagentes para o tratamento de distúrbios inflamatórios

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Publication number
BRPI0416591A
BRPI0416591A BRPI0416591-8A BRPI0416591A BRPI0416591A BR PI0416591 A BRPI0416591 A BR PI0416591A BR PI0416591 A BRPI0416591 A BR PI0416591A BR PI0416591 A BRPI0416591 A BR PI0416591A
Authority
BR
Brazil
Prior art keywords
treatment
reagents
methods
inflammatory disorders
compound
Prior art date
Application number
BRPI0416591-8A
Other languages
English (en)
Original Assignee
Combinatorx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34619466&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0416591(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Combinatorx Inc filed Critical Combinatorx Inc
Publication of BRPI0416591A publication Critical patent/BRPI0416591A/pt

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
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    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)

Abstract

"MéTODOS E REAGENTES PARA O TRATAMENTO DE DISTúRBIOS INFLAMATóRIOS". A presente invenção refere-se a um método para tratamento de um paciente diagnosticado com, ou sob risco de desenvolver, um distúrbio imunoinflamatório através da administração de um composto tricíclico e, opcionalmente, um corticosteróide ou outro composto ao paciente. A invenção refere-se também a uma composição farmacêutica contendo um composto tricíclico e um corticosteróide ou outro composto para o tratamento ou prevenção de um distúrbio imunoinflamatório.
BRPI0416591-8A 2003-11-13 2004-11-10 métodos e reagentes para o tratamento de distúrbios inflamatórios BRPI0416591A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52044603P 2003-11-13 2003-11-13
PCT/US2004/037638 WO2005048927A2 (en) 2003-11-13 2004-11-10 Methods and reagents for the treatment of inflammatory disorders

Publications (1)

Publication Number Publication Date
BRPI0416591A true BRPI0416591A (pt) 2007-01-30

Family

ID=34619466

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416591-8A BRPI0416591A (pt) 2003-11-13 2004-11-10 métodos e reagentes para o tratamento de distúrbios inflamatórios

Country Status (17)

Country Link
US (2) US20050187200A1 (pt)
EP (1) EP1691744A4 (pt)
JP (1) JP2007511521A (pt)
KR (1) KR20060118536A (pt)
CN (1) CN1901863A (pt)
AR (1) AR047726A1 (pt)
AU (1) AU2004291084A1 (pt)
BR (1) BRPI0416591A (pt)
CA (1) CA2545615A1 (pt)
IL (1) IL175610A0 (pt)
IS (1) IS8497A (pt)
NO (1) NO20062363L (pt)
RU (1) RU2006120408A (pt)
SG (1) SG148186A1 (pt)
TW (1) TW200529861A (pt)
WO (1) WO2005048927A2 (pt)
ZA (1) ZA200604250B (pt)

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US8008093B2 (en) * 2004-12-02 2011-08-30 The University Of North Carolina At Chapel Hill Inhibition of Hsp27 phosphorylation for the treatment of blistering disorders
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
WO2007019888A2 (en) * 2005-08-12 2007-02-22 Ctg Pharma S.R.L. Therapeutic compositions containing mesalamine and a co-agent for treating colon diseases
RU2008139625A (ru) * 2006-03-07 2010-04-20 Вертекс Фармасьютикалз Инкорпорейтед (Us) Композиции и способы лечения ревматоидного артрита
MX2010007393A (es) * 2008-01-03 2010-11-09 Abbott Biotech Ltd Anticipacion de eficacia a largo plazo de un compuesto en el tratamiento de psoriasis.
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
WO2011011594A2 (en) * 2009-07-23 2011-01-27 Shriners Hospitals For Children Intracellular toll-like receptors pathways and axonal degeneration
MX377877B (es) * 2013-01-14 2025-03-11 Infirst Healthcare Ltd Composiciones de solución sólida y su uso en el tratamiento del dolor intenso.
KR101567735B1 (ko) * 2014-12-09 2015-11-09 동국대학교 산학협력단 면역 조절제 및 글루코사민을 포함하는 건선 예방, 개선 또는 치료용 조성물
US10954265B2 (en) * 2016-10-14 2021-03-23 Van Andel Research Institute Structures and mechanism for the design of highly potent glucocorticoids
WO2018076108A1 (en) * 2016-10-25 2018-05-03 Uti Limited Partnership Treatment for progressive multiple sclerosis
US11510928B2 (en) * 2017-09-07 2022-11-29 Uti Limited Partnership Use of mirtazapine in the treatment of inflammatory disorders, autoimmune disease and PBC
CN107913279A (zh) * 2017-11-16 2018-04-17 钟汝华 一种治疗多种皮肤病的药膏
CN118924767B (zh) * 2024-07-25 2025-11-11 中南大学湘雅医院 孕烯醇酮作为活性成分在制备银屑病或特应性皮炎的治疗药物中的应用

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US4107306A (en) * 1973-01-16 1978-08-15 The Regents Of The University Of Michigan Process for treating proliferative skin disease
US4034087A (en) * 1973-12-17 1977-07-05 The Regents Of The University Of Michigan Pharmaceutical composition and process of treatment
US5286730A (en) * 1991-09-17 1994-02-15 American Home Products Corporation Method of treating immunoinflammatory disease
US6011005A (en) * 1997-09-18 2000-01-04 The Picower Institute For Medical Research Prevention of pregnancy miscarriages
US6140337A (en) * 1997-12-23 2000-10-31 Schering Corporation Methods for the treatment of mental disorders
US5900249A (en) * 1998-02-09 1999-05-04 Smith; David J. Multicomponent pain relief topical medication
US6677326B2 (en) * 1999-03-15 2004-01-13 Arakis, Ltd. Corticosteroid formulation comprising less than 2.5 mg prednisolone for once daily administration
DE60233414D1 (de) * 2001-07-09 2009-10-01 Combinatorx Inc Kombinationen für die behandlung entzündlicher erkrankungen

Also Published As

Publication number Publication date
CA2545615A1 (en) 2005-06-02
TW200529861A (en) 2005-09-16
CN1901863A (zh) 2007-01-24
WO2005048927A3 (en) 2006-01-26
US20050187200A1 (en) 2005-08-25
AR047726A1 (es) 2006-02-15
US20090075951A1 (en) 2009-03-19
IS8497A (is) 2006-06-02
JP2007511521A (ja) 2007-05-10
WO2005048927A2 (en) 2005-06-02
EP1691744A2 (en) 2006-08-23
KR20060118536A (ko) 2006-11-23
ZA200604250B (en) 2007-11-28
SG148186A1 (en) 2008-12-31
IL175610A0 (en) 2006-09-05
AU2004291084A1 (en) 2005-06-02
NO20062363L (no) 2006-08-11
RU2006120408A (ru) 2007-12-20
EP1691744A4 (en) 2007-12-26

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