BRPI0416843A8 - dímeros de triazina, composição compreendendo os mesmos, seus usos e processos de remoção e purificação de anticorpos - Google Patents

dímeros de triazina, composição compreendendo os mesmos, seus usos e processos de remoção e purificação de anticorpos

Info

Publication number
BRPI0416843A8
BRPI0416843A8 BRPI0416843A BRPI0416843A BRPI0416843A8 BR PI0416843 A8 BRPI0416843 A8 BR PI0416843A8 BR PI0416843 A BRPI0416843 A BR PI0416843A BR PI0416843 A BRPI0416843 A BR PI0416843A BR PI0416843 A8 BRPI0416843 A8 BR PI0416843A8
Authority
BR
Brazil
Prior art keywords
autoimmune diseases
compounds
purification
composition
methods
Prior art date
Application number
BRPI0416843A
Other languages
English (en)
Inventor
Ezzitouni Abdallah
D Cameron Alan
Zacharie Boulos
Grouix Brigitte
Penney Christopher
Fortin Daniel
Bienvenu Jean-François
Duceppe Jean-Simon
Houde Karine
Gagnon Lyne
Moreau Nancie
Wilb Nicole
D Abbott Shaun
Original Assignee
Prometic Biosciences Inc
Prometic Pharma Smt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prometic Biosciences Inc, Prometic Pharma Smt Ltd filed Critical Prometic Biosciences Inc
Publication of BRPI0416843A publication Critical patent/BRPI0416843A/pt
Publication of BRPI0416843A8 publication Critical patent/BRPI0416843A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/70—Other substituted melamines

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"dímeros de triazina para o tratamento de doenças auto-imunes". compostos contendo dois anéis de triazina mono- ou dissubstituídos, ligados covalentemente por um agente de ligação orgânico, mas não ligados diretamente entre si, podem ser usados para tratar doenças auto-imunes. as doenças auto-imunes, que são passíveis de tratamento com os compostos desta invenção, incluem artrite reumatóide, lúpus eritematoso sistêmico (sle), trombocitopenia idiopática (imune) (itp), glomerulonefrite e vasculite. a presente invenção também se refere à redução de toxicidade de medicamentos, que freqüentemente está associada às terapias tradicionais para doenças auto-imunes. os compostos também podem ser usados para ligação a anticorpo, in vitro ou ex vitro.
BRPI0416843A 2003-11-24 2004-11-22 dímeros de triazina, composição compreendendo os mesmos, seus usos e processos de remoção e purificação de anticorpos BRPI0416843A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52402103P 2003-11-24 2003-11-24
PCT/CA2004/002003 WO2005049607A1 (en) 2003-11-24 2004-11-22 Triazine dimers for the treatment of autoimmune diseases

Publications (2)

Publication Number Publication Date
BRPI0416843A BRPI0416843A (pt) 2007-02-13
BRPI0416843A8 true BRPI0416843A8 (pt) 2019-01-02

Family

ID=34619624

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416843A BRPI0416843A8 (pt) 2003-11-24 2004-11-22 dímeros de triazina, composição compreendendo os mesmos, seus usos e processos de remoção e purificação de anticorpos

Country Status (13)

Country Link
US (1) US7683061B2 (pt)
EP (1) EP1687297B1 (pt)
JP (1) JP5160788B2 (pt)
AU (1) AU2004291186B2 (pt)
BR (1) BRPI0416843A8 (pt)
CA (1) CA2554635C (pt)
DK (1) DK1687297T3 (pt)
ES (1) ES2501169T3 (pt)
IL (1) IL175814A0 (pt)
MX (1) MXPA06005879A (pt)
PL (1) PL1687297T3 (pt)
PT (1) PT1687297E (pt)
WO (1) WO2005049607A1 (pt)

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AU2006203826A1 (en) 2005-01-07 2006-07-13 Emory University CXCR4 antagonists for the treatment of HIV infection
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EP2016059B1 (en) * 2006-05-08 2016-12-07 Basf Se Triazine derivatives
EP2041067A4 (en) * 2006-07-11 2009-11-25 Univ Emory CXER4 ANTAGONISTS WITH DIAZINE AND TRIAZINE STRUCTURES FOR THE TREATMENT OF MEDICAL PROBLEMS
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USD751000S1 (en) 2013-06-17 2016-03-08 Ferno-Washington, Inc. Control panel of a patient transport device having surface ornamentation
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KR20160144412A (ko) 2014-04-04 2016-12-16 페르노-와싱턴, 인코포레이티드. 들것을 자동으로 액츄에이팅하기 위한 방법 및 시스템

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Also Published As

Publication number Publication date
US20070149528A1 (en) 2007-06-28
AU2004291186A1 (en) 2005-06-02
CA2554635C (en) 2013-06-18
ES2501169T3 (es) 2014-10-01
DK1687297T3 (da) 2014-09-22
EP1687297B1 (en) 2014-06-18
CA2554635A1 (en) 2005-06-02
EP1687297A4 (en) 2009-04-22
WO2005049607B1 (en) 2005-07-14
WO2005049607A1 (en) 2005-06-02
PL1687297T3 (pl) 2014-11-28
JP2007512259A (ja) 2007-05-17
JP5160788B2 (ja) 2013-03-13
IL175814A0 (en) 2006-10-05
BRPI0416843A (pt) 2007-02-13
MXPA06005879A (es) 2007-01-26
PT1687297E (pt) 2014-09-18
EP1687297A1 (en) 2006-08-09
AU2004291186B2 (en) 2012-01-19
US7683061B2 (en) 2010-03-23

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Owner name: PROMETIC PHARMA SMT LIMITED (CA)

B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
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