BRPI0416854B8 - suspensão aquosa estéril de ciclesonida adequada para nebulização, método para sua preparação e uso da dita suspensão, bem como produto farmacêutico - Google Patents

suspensão aquosa estéril de ciclesonida adequada para nebulização, método para sua preparação e uso da dita suspensão, bem como produto farmacêutico

Info

Publication number
BRPI0416854B8
BRPI0416854B8 BRPI0416854A BRPI0416854A BRPI0416854B8 BR PI0416854 B8 BRPI0416854 B8 BR PI0416854B8 BR PI0416854 A BRPI0416854 A BR PI0416854A BR PI0416854 A BRPI0416854 A BR PI0416854A BR PI0416854 B8 BRPI0416854 B8 BR PI0416854B8
Authority
BR
Brazil
Prior art keywords
suspension
nebulization
sterile aqueous
ciclesonide
preparation
Prior art date
Application number
BRPI0416854A
Other languages
English (en)
Inventor
Brueck-Scheffler Antje
Original Assignee
Astrazeneca Ab
Altana Pharma Ag
Covis Pharma B V
Nycomed Asset Man Gmbh
Nycomed Germany Holding Gmbh
Nycomed Gmbh
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34684543&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0416854(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab, Altana Pharma Ag, Covis Pharma B V, Nycomed Asset Man Gmbh, Nycomed Germany Holding Gmbh, Nycomed Gmbh, Takeda Gmbh filed Critical Astrazeneca Ab
Publication of BRPI0416854A publication Critical patent/BRPI0416854A/pt
Publication of BRPI0416854B1 publication Critical patent/BRPI0416854B1/pt
Publication of BRPI0416854B8 publication Critical patent/BRPI0416854B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"suspensões aquosas de ciclesonida para nebulização". a presente invenção refere-se a um método para a preparação de suspensões aquosas estéreis de ciclesonida por esterilização com calor úmido. a invenção refere-se também a composições farmacêuticas em particular a suspensões aquosas estéreis de ciclesonida para administração por nebulização na profilaxia e/ou tratamento de doenças respiratórias.
BRPI0416854A 2003-12-16 2004-12-15 suspensão aquosa estéril de ciclesonida adequada para nebulização, método para sua preparação e uso da dita suspensão, bem como produto farmacêutico BRPI0416854B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03028848.4 2003-12-16
EP03028848 2003-12-16
PCT/EP2004/053495 WO2005058935A2 (en) 2003-12-16 2004-12-15 Aqueous suspensions of ciclesonide for nebulisation

Publications (3)

Publication Number Publication Date
BRPI0416854A BRPI0416854A (pt) 2007-02-13
BRPI0416854B1 BRPI0416854B1 (pt) 2018-05-02
BRPI0416854B8 true BRPI0416854B8 (pt) 2021-05-25

Family

ID=34684543

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416854A BRPI0416854B8 (pt) 2003-12-16 2004-12-15 suspensão aquosa estéril de ciclesonida adequada para nebulização, método para sua preparação e uso da dita suspensão, bem como produto farmacêutico

Country Status (21)

Country Link
US (2) US20070117783A1 (pt)
EP (2) EP1697398B1 (pt)
JP (1) JP5001657B2 (pt)
KR (1) KR101086095B1 (pt)
CN (1) CN100513417C (pt)
AR (1) AR046892A1 (pt)
AU (1) AU2004298447B2 (pt)
BR (1) BRPI0416854B8 (pt)
CA (1) CA2549038C (pt)
CO (1) CO5700832A2 (pt)
EA (1) EA012388B1 (pt)
EC (1) ECSP066608A (pt)
IL (1) IL175461A (pt)
MY (1) MY159377A (pt)
NO (1) NO337225B1 (pt)
NZ (1) NZ547217A (pt)
PE (1) PE20050941A1 (pt)
TW (1) TWI350757B (pt)
UA (1) UA87123C2 (pt)
WO (1) WO2005058935A2 (pt)
ZA (1) ZA200603768B (pt)

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WO2021221656A1 (en) 2020-04-30 2021-11-04 Synedgen, Inc. Compositions and methods of use thereof
US20210346613A1 (en) * 2020-05-05 2021-11-11 Mahesh Kumar KHAITAN Controlled delivery device for treating coronavirus infections and methods thereof
US20220031712A1 (en) * 2020-06-23 2022-02-03 Cai Gu Huang Preparation of a pharmaceutical composition of olodaterol and budesonide
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Also Published As

Publication number Publication date
ZA200603768B (en) 2007-10-31
NZ547217A (en) 2009-05-31
AR046892A1 (es) 2005-12-28
WO2005058935A2 (en) 2005-06-30
EP1697398B1 (en) 2012-07-04
EP1697398A2 (en) 2006-09-06
TW200524615A (en) 2005-08-01
TWI350757B (en) 2011-10-21
CA2549038C (en) 2014-08-05
JP5001657B2 (ja) 2012-08-15
CN1890256A (zh) 2007-01-03
EP2319858B1 (en) 2017-08-09
CO5700832A2 (es) 2006-11-30
US20070117783A1 (en) 2007-05-24
CN100513417C (zh) 2009-07-15
KR101086095B1 (ko) 2011-11-25
AU2004298447B2 (en) 2011-04-21
WO2005058935A3 (en) 2006-05-18
CA2549038A1 (en) 2005-06-30
BRPI0416854A (pt) 2007-02-13
UA87123C2 (uk) 2009-06-25
NO337225B1 (no) 2016-02-15
HK1098486A1 (zh) 2007-07-20
PE20050941A1 (es) 2005-11-08
IL175461A (en) 2013-12-31
US20160015634A1 (en) 2016-01-21
IL175461A0 (en) 2006-09-05
NO20063047L (no) 2006-09-05
US11052042B2 (en) 2021-07-06
EA012388B1 (ru) 2009-10-30
BRPI0416854B1 (pt) 2018-05-02
JP2007513993A (ja) 2007-05-31
EA200601091A1 (ru) 2006-12-29
ECSP066608A (es) 2006-10-25
MY159377A (en) 2016-12-30
EP2319858A1 (en) 2011-05-11
AU2004298447A1 (en) 2005-06-30
KR20060122890A (ko) 2006-11-30

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