ECSP066608A - Suspensiones acuosas de ciclesonide para nebulización - Google Patents

Suspensiones acuosas de ciclesonide para nebulización

Info

Publication number
ECSP066608A
ECSP066608A EC2006006608A ECSP066608A ECSP066608A EC SP066608 A ECSP066608 A EC SP066608A EC 2006006608 A EC2006006608 A EC 2006006608A EC SP066608 A ECSP066608 A EC SP066608A EC SP066608 A ECSP066608 A EC SP066608A
Authority
EC
Ecuador
Prior art keywords
ciclesonide
nebulization
suspensions
waterproof
sterile aqueous
Prior art date
Application number
EC2006006608A
Other languages
English (en)
Inventor
Antje Brueck-Scheffler
Original Assignee
Altana Pharma A G
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34684543&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP066608(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Altana Pharma A G filed Critical Altana Pharma A G
Publication of ECSP066608A publication Critical patent/ECSP066608A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Esta invención se refiere a un método o procedimiento para la preparación de suspensiones acuosas estériles de ciclesonide mediante esterilización con calor húmedo. La invención se refiere adicionalmente a composiciones farmacéuticas, en particular a suspensiones acuosas estériles de ciclesonide para administración mediante nebulización en la profilaxis y/o el tratamiento de enfermedades respiratorias.
EC2006006608A 2003-12-16 2006-06-05 Suspensiones acuosas de ciclesonide para nebulización ECSP066608A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03028848 2003-12-16
PCT/EP2004/053495 WO2005058935A2 (en) 2003-12-16 2004-12-15 Aqueous suspensions of ciclesonide for nebulisation

Publications (1)

Publication Number Publication Date
ECSP066608A true ECSP066608A (es) 2006-10-25

Family

ID=34684543

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006608A ECSP066608A (es) 2003-12-16 2006-06-05 Suspensiones acuosas de ciclesonide para nebulización

Country Status (21)

Country Link
US (2) US20070117783A1 (es)
EP (2) EP2319858B1 (es)
JP (1) JP5001657B2 (es)
KR (1) KR101086095B1 (es)
CN (1) CN100513417C (es)
AR (1) AR046892A1 (es)
AU (1) AU2004298447B2 (es)
BR (1) BRPI0416854B8 (es)
CA (1) CA2549038C (es)
CO (1) CO5700832A2 (es)
EA (1) EA012388B1 (es)
EC (1) ECSP066608A (es)
IL (1) IL175461A (es)
MY (1) MY159377A (es)
NO (1) NO337225B1 (es)
NZ (1) NZ547217A (es)
PE (1) PE20050941A1 (es)
TW (1) TWI350757B (es)
UA (1) UA87123C2 (es)
WO (1) WO2005058935A2 (es)
ZA (1) ZA200603768B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2022796A1 (en) * 2007-08-07 2009-02-11 Nycomed GmbH Amorphous ciclesonide
US7984792B2 (en) * 2008-03-03 2011-07-26 Rolls-Royce Corporation Lubrication system
US20110262420A1 (en) * 2008-12-03 2011-10-27 Ltt Bio-Pharma Co., Ltd. Inhalant comprising modified superoxide dismutase
EP3311823B1 (en) 2009-09-02 2020-11-25 Synedgen, Inc. Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds
US10105356B2 (en) 2011-01-31 2018-10-23 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
CA2824432C (en) * 2011-01-31 2021-10-19 Genoa Pharmaceuticals, Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
MX2014001556A (es) 2011-08-12 2014-03-31 Boehringer Ingelheim Vetmed Composicion farmaceutica de sabor enmascarado.
AU2012296880A1 (en) 2011-08-18 2014-03-27 Astrazeneca Ab Pharmaceutical aerosol product for administration by oral or nasal inhalation
PH12014500551A1 (en) 2011-09-14 2014-04-21 Shionogi & Co Pharmaceutical composition for inhalation
EP2934544B1 (en) 2012-12-21 2018-11-07 Boehringer Ingelheim Vetmedica GmbH Pharmaceutical formulation comprising ciclesonide
SI2934479T1 (sl) 2012-12-21 2019-01-31 Boehringer Ingelheim Vetmedica Gmbh Ciklezonid za zdravljenje bolezni dihalnih poti pri konjih
EP4491180A1 (en) 2014-01-10 2025-01-15 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
MX370430B (es) 2014-06-18 2019-12-13 Boehringer Ingelheim Vetmedica Gmbh Antagonistas muscarínicos y sus combinaciones para el tratamiento de enfermedades de las vías respiratorias en caballos.
CA2960998A1 (en) * 2014-09-11 2016-03-17 Synedgen, Inc. Compositions and methods of use thereof
WO2017022814A1 (ja) * 2015-08-05 2017-02-09 第一三共株式会社 ネブライザー用組成物
CN106692163A (zh) * 2015-11-13 2017-05-24 天津金耀集团有限公司 一种吸入用环索奈德混悬液组合物
WO2019090405A1 (pt) * 2017-11-11 2019-05-16 Carvalho Junior Mario Virgilio De Medicamento de ciclesonida para cura e prevenção da gripe causada pelo vírus influenza
US20220023282A1 (en) * 2018-12-13 2022-01-27 Mannkind Corporation Compositions of Bedaquiline, Combinations Comprising Them, Processes for Their Preparation, Uses and Methods of Treatment Comprising Them
EP4142740A4 (en) 2020-04-30 2024-01-24 Synedgen, Inc. Compositions and methods of use thereof
US20210346613A1 (en) * 2020-05-05 2021-11-11 Mahesh Kumar KHAITAN Controlled delivery device for treating coronavirus infections and methods thereof
CN115835885B (zh) * 2020-06-23 2025-02-07 广州谷森制药有限公司 包含奥达特罗和布地奈德的药物组合物的制备
WO2022213101A1 (en) * 2021-04-01 2022-10-06 Vitrean Inc. Methods for manufacturing of highly concentrated hydrogels
WO2022231533A1 (en) * 2021-04-29 2022-11-03 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Process for the preparation of sterilized suspensions for the inhalation by nebulization

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE458986B (sv) * 1985-03-29 1989-05-29 Draco Ab Dosfoerpackning
SE8600632D0 (sv) * 1986-02-13 1986-02-13 Kabivitrum Ab Novel pharmaceutical composition
GR1001529B (el) * 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
US5346702A (en) * 1992-12-04 1994-09-13 Sterling Winthrop Inc. Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization
CN1062869C (zh) 1993-04-02 2001-03-07 比克·古尔顿·劳姆贝尔格化学公司 新型脱氢皮质醇衍生物
US5540930A (en) * 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
GB9410222D0 (en) 1994-05-21 1994-07-06 Glaxo Wellcome Australia Ltd Medicaments
DE4440337A1 (de) * 1994-11-11 1996-05-15 Dds Drug Delivery Services Ges Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
DE19541689A1 (de) 1994-11-14 1996-05-15 Byk Gulden Lomberg Chem Fab Kombinationsarzneimittel
DE19635498A1 (de) 1996-09-03 1998-03-26 Byk Gulden Lomberg Chem Fab Verfahren zur Epimerenanreicherung
US6120752A (en) * 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
SE9704186D0 (sv) 1997-11-14 1997-11-14 Astra Ab New composition of matter
US6598603B1 (en) * 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
TWI243687B (en) * 1998-04-21 2005-11-21 Teijin Ltd Pharmaceutical composition for application to mucosa
US6264923B1 (en) 1998-05-13 2001-07-24 3M Innovative Properties Company Medicinal aerosol formulation of ciclesonide and related compounds
ES2216517T3 (es) 1998-05-29 2004-10-16 Skyepharma Canada Inc. Composiciones de microcapsulas termoprotegidas y procedimiento para su esterilizacion terminal con vapor.
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
IT1303692B1 (it) * 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
IT1313553B1 (it) * 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
AR026072A1 (es) * 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa
AR026073A1 (es) * 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
EP1142565A4 (en) 1999-10-20 2004-03-17 Teijin Ltd AQUEOUS THERAPEUTIC COMPOSITIONS
US20020183292A1 (en) * 2000-10-31 2002-12-05 Michel Pairet Pharmaceutical compositions based on anticholinergics and corticosteroids
DE10062712A1 (de) * 2000-12-15 2002-06-20 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden
BR0115584A (pt) * 2000-11-24 2003-09-23 Breath Ltd Esterilização de produtos farmacêuticos
US6667344B2 (en) * 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
DE10145361A1 (de) * 2001-09-14 2003-04-03 Pari Gmbh Verfahren zur Herstellung von flüssigen, sterilen Zubereitungen zur Inhalation
JP2005508220A (ja) 2001-10-24 2005-03-31 パーリ・ゲーエムベーハー 薬用組成物調製用具
US8541399B2 (en) 2002-02-19 2013-09-24 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals
AU2003208212A1 (en) 2002-03-04 2003-09-16 Nymox Corporation Spheron components useful in determining compounds capable of treating symptoms of alzheimer's disease, and treatments and animal models produced therefrom
JP4720086B2 (ja) 2002-04-12 2011-07-13 味の素株式会社 動脈硬化予防用組成物
ITMI20020808A1 (it) 2002-04-17 2003-10-17 Chiesi Farma Spa Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione
JP4364486B2 (ja) 2002-07-02 2009-11-18 帝人株式会社 無菌水性懸濁製剤
RS57455B1 (sr) 2002-07-02 2018-09-28 Astrazeneca Ab Sterilna vodena suspenzija koja sadrži ciklezonid
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
ATE472329T1 (de) * 2002-08-30 2010-07-15 Nycomed Gmbh Verwendung der kombination von ciclesonid und antihistaminika zur behandlung von allergischer rhinitis
WO2004029574A1 (ja) 2002-09-24 2004-04-08 Fujitsu Limited 歪み波形制御装置、歪み規制部材、歪み波形制御装置の歪み波形制御方法、及び歪み波形制御プログラム
WO2004032980A1 (en) 2002-10-04 2004-04-22 Elan Pharma International Limited Gamma irradiation of solid nanoparticulate active agents
ITMI20022674A1 (it) * 2002-12-18 2004-06-19 Chiesi Farma Spa Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
EP1454636A1 (en) 2003-03-04 2004-09-08 Dompé S.P.A. Sterilization of glucocorticoid drug particles for pulmonary delivery
MY143936A (en) 2003-03-27 2011-07-29 Nycomed Gmbh Process for preparing crystalline ciclesonide with defined particle size
TWI359675B (en) * 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
PL1670482T5 (pl) * 2003-09-16 2022-10-03 Covis Pharma Gmbh Zastosowanie cyklezonidu w leczeniu chorób układu oddechowego
DE10347994A1 (de) * 2003-10-15 2005-06-16 Pari GmbH Spezialisten für effektive Inhalation Wässrige Aerosol-Zubereitung
EP1574222B1 (en) 2004-03-12 2011-02-09 Cipla Ltd. Sterilization process for steroids
GB0410995D0 (en) 2004-05-17 2004-06-23 Norton Healthcare Ltd Heat sterilization of glucocorticosteroids
ITSA20040012A1 (it) 2004-09-07 2004-12-07 Genetec S P A Processo di sterilizzazione di un glucocorticosteroide.
GB0425266D0 (en) 2004-11-16 2004-12-15 Norton Healthcare Ltd Pharmaceutical manufacturing process

Also Published As

Publication number Publication date
HK1098486A1 (zh) 2007-07-20
ZA200603768B (en) 2007-10-31
CN1890256A (zh) 2007-01-03
EP2319858B1 (en) 2017-08-09
KR20060122890A (ko) 2006-11-30
US11052042B2 (en) 2021-07-06
EP1697398A2 (en) 2006-09-06
BRPI0416854B8 (pt) 2021-05-25
CO5700832A2 (es) 2006-11-30
PE20050941A1 (es) 2005-11-08
BRPI0416854B1 (pt) 2018-05-02
AR046892A1 (es) 2005-12-28
IL175461A0 (en) 2006-09-05
EA012388B1 (ru) 2009-10-30
JP2007513993A (ja) 2007-05-31
KR101086095B1 (ko) 2011-11-25
CA2549038C (en) 2014-08-05
BRPI0416854A (pt) 2007-02-13
MY159377A (en) 2016-12-30
NO337225B1 (no) 2016-02-15
US20070117783A1 (en) 2007-05-24
WO2005058935A3 (en) 2006-05-18
TWI350757B (en) 2011-10-21
WO2005058935A2 (en) 2005-06-30
EA200601091A1 (ru) 2006-12-29
NZ547217A (en) 2009-05-31
NO20063047L (no) 2006-09-05
EP1697398B1 (en) 2012-07-04
EP2319858A1 (en) 2011-05-11
UA87123C2 (uk) 2009-06-25
US20160015634A1 (en) 2016-01-21
AU2004298447B2 (en) 2011-04-21
JP5001657B2 (ja) 2012-08-15
CA2549038A1 (en) 2005-06-30
AU2004298447A1 (en) 2005-06-30
TW200524615A (en) 2005-08-01
CN100513417C (zh) 2009-07-15
IL175461A (en) 2013-12-31

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