BRPI0416922A - composições e métodos para medição de concentrações de analito - Google Patents
composições e métodos para medição de concentrações de analitoInfo
- Publication number
- BRPI0416922A BRPI0416922A BRPI0416922-0A BRPI0416922A BRPI0416922A BR PI0416922 A BRPI0416922 A BR PI0416922A BR PI0416922 A BRPI0416922 A BR PI0416922A BR PI0416922 A BRPI0416922 A BR PI0416922A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- protein
- compositions
- fluorescent
- periplasmic binding
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000012491 analyte Substances 0.000 title abstract 2
- 108010092494 Periplasmic binding proteins Proteins 0.000 abstract 4
- 102000037865 fusion proteins Human genes 0.000 abstract 3
- 108020001507 fusion proteins Proteins 0.000 abstract 3
- XDIYNQZUNSSENW-NUVHGKSTSA-N (2r,3s,4s,5r)-2,3,4,5,6-pentahydroxyhexanal;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O XDIYNQZUNSSENW-NUVHGKSTSA-N 0.000 abstract 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 102000034287 fluorescent proteins Human genes 0.000 abstract 1
- 108091006047 fluorescent proteins Proteins 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Diabetes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
"COMPOSIçõES E MéTODOS PARA MEDIçãO DE CONCENTRAçõES DE ANALITO". A presente invenção refere-se a proteínas de fusão compreendendo pelo menos uma proteína de ligação periplasmática funcional, pelo menos uma fração de rotulagem e pelo menos uma proteína fluorescente. Em uma modalidade, a proteína de ligação periplasmática é uma proteína de ligação a glicose-galactose funcional (GGBP). A invenção também se refere a métodos para quantificar um analito, por exemplo, glicose, numa célula ou tecido, compreendendo a administração de uma composição composta por uma parte de proteína de fusão de ligação periplasmática fluorescente à célula ou tecido, e medição da fluorescência da proteína de fusão de ligação periplasmática fluorescente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/721,091 US20050112685A1 (en) | 2003-11-26 | 2003-11-26 | Compositions and methods for measuring analyte concentrations |
| PCT/US2004/038330 WO2005054855A1 (en) | 2003-11-26 | 2004-11-16 | Compositions and methods for measuring analyte concentrations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0416922A true BRPI0416922A (pt) | 2007-01-23 |
Family
ID=34591723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0416922-0A BRPI0416922A (pt) | 2003-11-26 | 2004-11-16 | composições e métodos para medição de concentrações de analito |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20050112685A1 (pt) |
| EP (1) | EP1709446A1 (pt) |
| JP (1) | JP2007513331A (pt) |
| CN (1) | CN1898565A (pt) |
| AU (1) | AU2004295683A1 (pt) |
| BR (1) | BRPI0416922A (pt) |
| CA (1) | CA2546949A1 (pt) |
| NO (1) | NO20062973L (pt) |
| WO (1) | WO2005054855A1 (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050239155A1 (en) * | 2002-01-04 | 2005-10-27 | Javier Alarcon | Entrapped binding protein as biosensors |
| US20030153026A1 (en) * | 2002-01-04 | 2003-08-14 | Javier Alarcon | Entrapped binding protein as biosensors |
| DE602005022704D1 (de) * | 2004-06-09 | 2010-09-16 | Dickinson And Co | Sensor für mehrere analyte |
| US20060040327A1 (en) * | 2004-08-18 | 2006-02-23 | Terry Amiss | Methods of screening proteins |
| ATE540048T1 (de) * | 2004-10-14 | 2012-01-15 | Carnegie Inst Of Washington | Neurotransmittersensoren und verfahren zu ihrer verwendung |
| AU2005295656B2 (en) * | 2004-10-14 | 2011-08-04 | Carnegie Institution Of Washington | Development of sensitive FRET sensors and methods of using the same |
| US20090178149A1 (en) * | 2005-03-03 | 2009-07-09 | Sylvie Lalonde | Polyamine Sensors and Methods of Using the Same |
| CA2599852A1 (en) * | 2005-03-04 | 2006-09-14 | Carnegie Institution Of Washington | Environmentally stable sensors and methods of using the same |
| CA2618994C (en) * | 2005-09-01 | 2017-04-11 | Medical Research Council | Improved inorganic phosphate assays |
| EP1933614B1 (en) | 2005-10-14 | 2010-11-24 | Carnegie Institution of Washington | Sucrose biosensors and methods of using the same |
| EP1934240B1 (en) * | 2005-10-14 | 2010-09-15 | Carnegie Institution Of Washington | Phosphate biosensors and methods of using the same |
| AU2006315332A1 (en) * | 2005-11-16 | 2007-05-24 | Carnegie Institution Of Washington | Multimeric biosensors and methods of using the same |
| US20120122115A1 (en) * | 2006-04-25 | 2012-05-17 | Sayre Richard T | Bacterial quorum sensing biosensor |
| EP2061884A4 (en) * | 2006-08-11 | 2010-03-24 | Life Technologies Corp | SENSOR PROTEINS AND TEST PROCEDURES THEREFOR |
| US20110229415A1 (en) * | 2007-08-06 | 2011-09-22 | Sylvia Daunert | Semi-synthetic antibodies as recognition elements |
| CA2698076A1 (en) * | 2007-08-29 | 2009-03-05 | Plant Sensory System, Llc. | Metabolic regulators |
| US8742204B2 (en) * | 2007-08-29 | 2014-06-03 | Plant Sensory Systems, Llc | Metabolic regulators |
| US8741591B2 (en) * | 2009-10-09 | 2014-06-03 | The Research Foundation For The State University Of New York | pH-insensitive glucose indicator protein |
| JP2016508727A (ja) * | 2013-02-25 | 2016-03-24 | ウェルスタット ダイアグノスティクス,エルエルシー | 電気化学発光(ecl)検出試薬および酵素活性を測定するための関連の方法 |
| WO2017066441A1 (en) * | 2015-10-13 | 2017-04-20 | The Research Foundation For The State University Of New York | Cleavable fusion tag for protein overexpression and purification |
| EP3377643A4 (en) * | 2015-11-20 | 2019-10-02 | Duke University | GLUCOSE Biosensor and uses thereof |
| DE102019132525B3 (de) * | 2019-11-29 | 2021-03-18 | ICHORtec GmbH | Verfahren und Optode zur Bestimmung der Konzentration eines Analyten in einer Probenflüssigkeit |
| CN113484525A (zh) * | 2021-07-05 | 2021-10-08 | 海南医学院 | 一种肝素结合蛋白(hbp)时间分辨荧光免疫层析半定量检测试纸条 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030064480A1 (en) * | 1990-06-28 | 2003-04-03 | Leander Lauffer | Fusion proteins with immunoglobulin portions, the preparation and use thereof |
| US7253264B1 (en) * | 1990-06-28 | 2007-08-07 | Sanofi-Arentideutschland GmbH | Immunoglobulin fusion proteins, their production and use |
| US5998204A (en) * | 1997-03-14 | 1999-12-07 | The Regents Of The University Of California | Fluorescent protein sensors for detection of analytes |
| JP4472169B2 (ja) * | 1997-12-31 | 2010-06-02 | デューク ユニバーシティ | バイオセンサー |
| DE69941085D1 (de) * | 1998-07-17 | 2009-08-20 | Univ Maryland | Manipulierte proteine zum analyten nachweis |
| US6432723B1 (en) * | 1999-01-22 | 2002-08-13 | Clinical Micro Sensors, Inc. | Biosensors utilizing ligand induced conformation changes |
| US7060793B2 (en) * | 1999-05-21 | 2006-06-13 | The Regents Of The University Of California | Circularly permuted fluorescent protein indicators |
| US7109315B2 (en) * | 2000-03-15 | 2006-09-19 | Bruce J. Bryan | Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items |
| US6969597B2 (en) * | 2001-02-21 | 2005-11-29 | Clontech Laboratories, Inc. | Nucleic acids encoding non aggregating fluorescent proteins and methods for using the same |
| JP4215512B2 (ja) * | 2001-02-26 | 2009-01-28 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 非オリゴマー化タンデム蛍光性タンパク質 |
| EP1427856B1 (en) * | 2001-09-18 | 2011-05-11 | Carnegie Institution Of Washington | Fusion proteins useful for detecting analytes |
| WO2003054158A2 (en) * | 2001-12-19 | 2003-07-03 | The University Of Chicago | Rapidly maturing fluorescent proteins and methods for using the same |
| US6855556B2 (en) * | 2002-01-04 | 2005-02-15 | Becton, Dickinson And Company | Binding protein as biosensors |
| US20030153026A1 (en) * | 2002-01-04 | 2003-08-14 | Javier Alarcon | Entrapped binding protein as biosensors |
| US7064103B2 (en) * | 2002-01-04 | 2006-06-20 | Becton, Dickinson And Company | Binding protein as biosensors |
| KR101107630B1 (ko) * | 2002-10-16 | 2012-01-25 | 듀크 유니버시티 | 바이오센서 |
-
2003
- 2003-11-26 US US10/721,091 patent/US20050112685A1/en not_active Abandoned
-
2004
- 2004-11-16 AU AU2004295683A patent/AU2004295683A1/en not_active Abandoned
- 2004-11-16 WO PCT/US2004/038330 patent/WO2005054855A1/en not_active Ceased
- 2004-11-16 JP JP2006541317A patent/JP2007513331A/ja active Pending
- 2004-11-16 CA CA002546949A patent/CA2546949A1/en not_active Abandoned
- 2004-11-16 BR BRPI0416922-0A patent/BRPI0416922A/pt not_active Application Discontinuation
- 2004-11-16 CN CNA2004800383766A patent/CN1898565A/zh active Pending
- 2004-11-16 EP EP04811146A patent/EP1709446A1/en not_active Withdrawn
-
2006
- 2006-06-26 NO NO20062973A patent/NO20062973L/no not_active Application Discontinuation
-
2007
- 2007-06-08 US US11/760,506 patent/US20080032312A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20080032312A1 (en) | 2008-02-07 |
| AU2004295683A1 (en) | 2005-06-16 |
| CA2546949A1 (en) | 2005-06-16 |
| JP2007513331A (ja) | 2007-05-24 |
| CN1898565A (zh) | 2007-01-17 |
| NO20062973L (no) | 2006-08-23 |
| WO2005054855A1 (en) | 2005-06-16 |
| EP1709446A1 (en) | 2006-10-11 |
| US20050112685A1 (en) | 2005-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |