BRPI0417029A - malaeto ou tosilado de 7-[4-(4-clorobenzilóxi) benzenossulfonil]-8-metóxi-3-metil-2,3,4,5-tetraidro- 1h-3-benzazepìnio como antipsicótico - Google Patents

malaeto ou tosilado de 7-[4-(4-clorobenzilóxi) benzenossulfonil]-8-metóxi-3-metil-2,3,4,5-tetraidro- 1h-3-benzazepìnio como antipsicótico

Info

Publication number
BRPI0417029A
BRPI0417029A BRPI0417029-6A BRPI0417029A BRPI0417029A BR PI0417029 A BRPI0417029 A BR PI0417029A BR PI0417029 A BRPI0417029 A BR PI0417029A BR PI0417029 A BRPI0417029 A BR PI0417029A
Authority
BR
Brazil
Prior art keywords
chlorobenzyloxy
benzenesulfonyl
tetrahydro
methoxy
antipsychotic
Prior art date
Application number
BRPI0417029-6A
Other languages
English (en)
Inventor
David Clapham
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BRPI0417029A publication Critical patent/BRPI0417029A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

"MALEATO OU TOSILADO DE 7-¢4-(4-CLOROBENZILóXI) BENZENOSSULFONIL!-8-METóXI-3-METIL-2,3,4,5-TETRAIDRO- 1H-3BENZAZEPìNIO COMO ANTIPSICóTICO)". A presente invenção se refere a novos sais de 7¢4-(4-clorobenzilóxi) benzenossulfonil!-8-metóxi-3-metil2,3,4,5-tetraidro-1H-3-benzazepin a e a seu solvato farmaceuticamente aceitável, formulações farmacêuticas, processos para sua preparação e seu uso em medicina. As entidades quimicas são utilizáveis em terapia, em particular como agentes antipsicóticos.
BRPI0417029-6A 2003-11-28 2004-11-25 malaeto ou tosilado de 7-[4-(4-clorobenzilóxi) benzenossulfonil]-8-metóxi-3-metil-2,3,4,5-tetraidro- 1h-3-benzazepìnio como antipsicótico BRPI0417029A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0327740.7A GB0327740D0 (en) 2003-11-28 2003-11-28 Novel compounds
PCT/EP2004/013416 WO2005051916A1 (en) 2003-11-28 2004-11-25 7-[4-(4-chlorobenzyloxy) benzenesulfonyl]-8-methoxy-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepinium maleate or tosylate as antipsychotics

Publications (1)

Publication Number Publication Date
BRPI0417029A true BRPI0417029A (pt) 2007-02-06

Family

ID=29798028

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0417029-6A BRPI0417029A (pt) 2003-11-28 2004-11-25 malaeto ou tosilado de 7-[4-(4-clorobenzilóxi) benzenossulfonil]-8-metóxi-3-metil-2,3,4,5-tetraidro- 1h-3-benzazepìnio como antipsicótico

Country Status (18)

Country Link
US (1) US20070275948A1 (pt)
EP (1) EP1687279A1 (pt)
JP (1) JP2007512285A (pt)
KR (1) KR20060103322A (pt)
CN (1) CN1906170A (pt)
AR (1) AR046719A1 (pt)
AU (1) AU2004293179A1 (pt)
BR (1) BRPI0417029A (pt)
CA (1) CA2547444A1 (pt)
GB (1) GB0327740D0 (pt)
IL (1) IL175663A0 (pt)
IS (1) IS8500A (pt)
MA (1) MA28177A1 (pt)
NO (1) NO20062970L (pt)
RU (1) RU2006122959A (pt)
TW (1) TW200528433A (pt)
WO (1) WO2005051916A1 (pt)
ZA (1) ZA200603781B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0510599D0 (en) * 2005-05-24 2005-06-29 Glaxo Group Ltd Novel compounds
GB0603087D0 (en) * 2006-02-15 2006-03-29 Glaxo Group Ltd Novel use
NZ586675A (en) * 2008-01-08 2012-04-27 Merck Sharp & Dohme Pharmaceutically acceptable salts of 2-{ 4-[(3s)-piperidin-3- yl]phenyl} -2h-indazole-7-carboxamide
CA2970502A1 (en) * 2014-12-12 2016-06-16 The Schepens Eye Research Institute, Inc. Gdnf induction for the treatment of retinal disorders
JP7185633B2 (ja) 2017-02-17 2022-12-07 トレベナ・インコーポレイテッド ７員アザ複素環を含有するデルタ－オピオイド受容体調節化合物、その使用方法及び製造方法
US20210347758A1 (en) 2018-10-03 2021-11-11 Tesaro, Inc. Crystalline Forms of Niraparib Freebase
EP4236939A4 (en) * 2020-10-27 2024-08-07 Trevena, Inc. Crystalline and amorphous forms of a delta-opioid modulator
CN115998724B (zh) * 2023-03-28 2023-06-16 中国人民解放军军事科学院军事医学研究院 布洛芬在抗幻觉作用药物中的新用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005518414A (ja) * 2001-12-21 2005-06-23 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー ドーパミン受容体のモジュレーターとしての７−スルホニル−３−ベンゾアゼピン誘導体およびｃｎｓ障害の治療のためのその使用
AU2003215558A1 (en) * 2002-02-13 2003-09-04 Glaxo Group Limited Benzenesulfonamide derivatives as antipsychotic agents
MY133587A (en) * 2002-05-29 2007-11-30 Glaxo Group Ltd Aromatic sulfones and their medical use

Also Published As

Publication number Publication date
CN1906170A (zh) 2007-01-31
CA2547444A1 (en) 2005-06-09
AR046719A1 (es) 2005-12-21
KR20060103322A (ko) 2006-09-28
US20070275948A1 (en) 2007-11-29
WO2005051916A1 (en) 2005-06-09
EP1687279A1 (en) 2006-08-09
TW200528433A (en) 2005-09-01
ZA200603781B (en) 2007-09-26
MA28177A1 (fr) 2006-09-01
AU2004293179A1 (en) 2005-06-09
GB0327740D0 (en) 2003-12-31
RU2006122959A (ru) 2008-01-10
IS8500A (is) 2006-06-08
JP2007512285A (ja) 2007-05-17
NO20062970L (no) 2006-08-21
IL175663A0 (en) 2006-09-05

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.