BRPI0417736A - seqüência de dna e preparo recombinante dos principais alérgenos do grupo 4 dos cereais - Google Patents

seqüência de dna e preparo recombinante dos principais alérgenos do grupo 4 dos cereais

Info

Publication number
BRPI0417736A
BRPI0417736A BRPI0417736-3A BRPI0417736A BRPI0417736A BR PI0417736 A BRPI0417736 A BR PI0417736A BR PI0417736 A BRPI0417736 A BR PI0417736A BR PI0417736 A BRPI0417736 A BR PI0417736A
Authority
BR
Brazil
Prior art keywords
seq
dna
nucleotides
amino acids
allergens
Prior art date
Application number
BRPI0417736-3A
Other languages
English (en)
Inventor
Helmut Fiebig
Andreas Nandy
Oliver Cromwell
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BRPI0417736A publication Critical patent/BRPI0417736A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"SEQüêNCIA DE DNA E PREPARO RECOMBINANTE DOS PRINCIPAIS ALéRGENOS DO GRUPO 4 DOS CEREAIS". A presente invenção refere-se ao fornecimento de seqüências de DNA dos alérgenos principais do grupo 4 a partir de cereais. A invenção também engloba fragmentos, novas combinações de seqüências parciais e mutantes de interesse com uma ação hipoalergênica. As moléculas de DNA recombinante e os polipeptídeos derivados, fragmentos, novas combinações de seqüências parciais e variantes podem ser usados para a terapia de doenças alérgicas a pólen. As proteínas preparadas por métodos recombinantes podem ser empregadas para diagnose in vitro e in vivo de alergias a pólen.
BRPI0417736-3A 2003-12-16 2004-12-01 seqüência de dna e preparo recombinante dos principais alérgenos do grupo 4 dos cereais BRPI0417736A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10359351A DE10359351A1 (de) 2003-12-16 2003-12-16 DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden
PCT/EP2004/013664 WO2005059136A2 (de) 2003-12-16 2004-12-01 Dna-sequenz und rekombinante herstellung von gruppe-4 majorallergenen aus getreiden

Publications (1)

Publication Number Publication Date
BRPI0417736A true BRPI0417736A (pt) 2007-04-03

Family

ID=34683486

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0417736-3A BRPI0417736A (pt) 2003-12-16 2004-12-01 seqüência de dna e preparo recombinante dos principais alérgenos do grupo 4 dos cereais

Country Status (14)

Country Link
US (3) US7935347B2 (pt)
EP (3) EP2261337B1 (pt)
JP (1) JP4960102B2 (pt)
CN (2) CN1894410A (pt)
AT (1) ATE501257T1 (pt)
AU (1) AU2004299600A1 (pt)
BR (1) BRPI0417736A (pt)
CA (3) CA2873261C (pt)
DE (2) DE10359351A1 (pt)
ES (3) ES2443302T3 (pt)
PL (3) PL1709177T3 (pt)
PT (3) PT2261336E (pt)
RU (1) RU2373283C2 (pt)
WO (1) WO2005059136A2 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10359351A1 (de) * 2003-12-16 2005-07-21 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden
EP3125933B1 (en) 2014-03-31 2022-05-18 Boehringer Ingelheim Vetmedica GmbH Improved modular antigen transportation molecules and uses therof
US10898568B2 (en) 2015-09-30 2021-01-26 Boehringer Ingelheim Vetmedica Gmbh Modular antigen transportation molecules and uses thereof in animals

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5762943A (en) * 1996-05-14 1998-06-09 Ribi Immunochem Research, Inc. Methods of treating type I hypersensitivity using monophosphoryl lipid A
DE19918682A1 (de) * 1999-04-23 2000-10-26 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung eines Graminaen-Allergens
US7214786B2 (en) * 2000-12-14 2007-05-08 Kovalic David K Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
WO2003000898A1 (en) * 2001-06-22 2003-01-03 Syngenta Participations Ag Plant genes involved in defense against pathogens
AUPR779201A0 (en) 2001-09-20 2001-10-11 University Of Melbourne, The Immunotherapeutic and immunoprophylactic reagents
AU2002328225A1 (en) 2001-09-21 2003-04-01 Affinium Pharmaceuticals, Inc. Bacterial polypeptides involved in protein processing
PT2392591T (pt) * 2002-06-25 2018-05-23 Merck Patent Gmbh Sequência de adn e produção recombinante do alergénio do pólen das gramíneas phl p4
DE10359351A1 (de) * 2003-12-16 2005-07-21 Merck Patent Gmbh DNA-Sequenz und rekombinante Herstellung von Gruppe-4 Majorallergenen aus Getreiden

Also Published As

Publication number Publication date
EP2261337A1 (de) 2010-12-15
PL1709177T3 (pl) 2011-07-29
PL2261336T3 (pl) 2014-02-28
PL2261337T3 (pl) 2014-02-28
CA2873261C (en) 2016-11-22
CA2549573C (en) 2015-03-17
EP1709177A2 (de) 2006-10-11
EP1709177B1 (de) 2011-03-09
DE502004012294D1 (de) 2011-04-21
WO2005059136A2 (de) 2005-06-30
ATE501257T1 (de) 2011-03-15
AU2004299600A1 (en) 2005-06-30
DE10359351A1 (de) 2005-07-21
WO2005059136A3 (de) 2005-09-01
EP2261336B1 (de) 2013-10-16
ES2442951T3 (es) 2014-02-14
RU2373283C2 (ru) 2009-11-20
PT2261336E (pt) 2014-01-10
US7935347B2 (en) 2011-05-03
JP2008504004A (ja) 2008-02-14
CA2549573A1 (en) 2005-06-30
ES2443302T3 (es) 2014-02-18
RU2006125511A (ru) 2008-01-27
CA2945267A1 (en) 2005-06-30
EP2261337B1 (de) 2013-10-23
PT1709177E (pt) 2011-06-17
US20080108561A1 (en) 2008-05-08
PT2261337E (pt) 2014-01-16
CN1894410A (zh) 2007-01-10
JP4960102B2 (ja) 2012-06-27
CN103305531A (zh) 2013-09-18
US9309297B2 (en) 2016-04-12
ES2363015T3 (es) 2011-07-18
US20170246317A1 (en) 2017-08-31
CA2873261A1 (en) 2005-06-30
EP2261336A1 (de) 2010-12-15
US20130164313A1 (en) 2013-06-27

Similar Documents

Publication Publication Date Title
CA2413045C (en) Expression system
JPH07504565A (ja) ワクチンおよび診断に有用なＨｅｌｉｃｏｂａｃｔｅｒｐｙｌｏｒｉタンパク質
HUP0001817A2 (hu) Chlorella víruspromóterek
Egelseer et al. Characterization of an S-layer glycoprotein produced in the course of S-layer variation of Bacillus stearothermophilu s ATCC 12980 and sequencing and cloning of the sbsD gene encoding the protein moiety
JP2009509553A5 (pt)
JP6836904B2 (ja) シマツナソおよびコウマ由来のｗｕｓｃｈｅｌ関連ホメオボックス４（ｗｏｘ４）タンパク質をコードするヌクレオチド配列および使用方法
BRPI0417736A (pt) seqüência de dna e preparo recombinante dos principais alérgenos do grupo 4 dos cereais
AU2014352999A1 (en) Nucleotide sequence encoding WUSCHEL-related homeobox4 (WOX4) protein from Corchorus olitorius and Corchorus capsularis and methods of use for same
CA2370393A1 (en) Dna sequence, and recombinant production of a gramineae allergen
RU2001130165A (ru) Последовательность ДНК и получение аллергена злаковых рекомбинантным способом
ATE550349T1 (de) Dna-sequenz und rekombinante herstellung des graspollen-allergens phl p4
WO2024023790A1 (en) Vaccine constructs comprising tuberculosis antigens
DE69730814D1 (de) DAS NucA PROTEIN VON HAEMOPHILUS INFLUENZAE UND DESSEN KODIERENDER GEN
RU2000111744A (ru) Очищенная и выделенная днк, химерный полинуклеотид, вектор экспрессии и клетка-хозяин
CN114437195A (zh) 一种开发肿瘤免疫类药物的环形rna技术平台
GB2621127A (en) Vaccine constructs comprising tuberculosis antigens
CN100469882C (zh) 重组幽门螺杆菌粘附素保守区的制备及用途
CN101906424B (zh) 一种重组人干扰素α2b DNA片段及编码的蛋白质
JP2006501863A5 (pt)
CN121555559A (zh) 一种小麦小分子GTP酶TaRac1基因及其在小麦抗条锈病中的应用
Kobayashi et al. Nucleotide sequence of MPB63 gene in Mycobacterium bovis BCG Tokyo
GENE PATENT ABSTRACP5
Donatelli et al. Conservation of H3N2 influenza viruses in pigs: Antigenic and genomic analysis
Cole et al. in Clostridium perfringens
Baylor et al. Molecular characterization of the structural-functional domains of the influenza A/WSN/33 matrix (Mi) protein

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C12N 15/29 , C07K 14/415 , A61K 38/56 , A61K 39/36 , A61K 31/7088

Ipc: C12N 15/29 (2006.01), A61K 39/36 (2006.01), C07K 1

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements