BRPI0417971A - método para a produção de ácidos 2-( fenoximetil)benzóicos substituìdos - Google Patents

método para a produção de ácidos 2-( fenoximetil)benzóicos substituìdos

Info

Publication number
BRPI0417971A
BRPI0417971A BRPI0417971-4A BRPI0417971A BRPI0417971A BR PI0417971 A BRPI0417971 A BR PI0417971A BR PI0417971 A BRPI0417971 A BR PI0417971A BR PI0417971 A BRPI0417971 A BR PI0417971A
Authority
BR
Brazil
Prior art keywords
compound
substituted
production
phenoxymethyl
benzoic acids
Prior art date
Application number
BRPI0417971-4A
Other languages
English (en)
Inventor
Wolfgang Fiedler
Bernd Neises
Jochen Hachtel
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of BRPI0417971A publication Critical patent/BRPI0417971A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

"MéTODO PARA A PRODUçãO DE áCIDOS 2(FENOXIMETIL)BENZóICOS SUBSTITUìDOS". A presente invenção refere-se a um processo para a preparação de um composto da fórmula geral (I), na qual: a) um composto (II) é reagido na presença de uma base B1 com um composto (III) e b) o composto (IV), formado como intermediário na etapa a), é reagido, na presença de uma base B2, com um composto (V), para dar o composto da fórmula geral (I)
BRPI0417971-4A 2003-12-22 2004-12-22 método para a produção de ácidos 2-( fenoximetil)benzóicos substituìdos BRPI0417971A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10360525A DE10360525B3 (de) 2003-12-22 2003-12-22 Verfahren zur Herstellung von substituierten 2-(Phenoxymethyl)-benzoesäuren
PCT/EP2004/014602 WO2005061427A2 (de) 2003-12-22 2004-12-22 Verfahren zur herstellung von substituierten 2-(phenoxymethyl)-benzoesäuren

Publications (1)

Publication Number Publication Date
BRPI0417971A true BRPI0417971A (pt) 2007-04-17

Family

ID=34706420

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0417971-4A BRPI0417971A (pt) 2003-12-22 2004-12-22 método para a produção de ácidos 2-( fenoximetil)benzóicos substituìdos

Country Status (14)

Country Link
EP (1) EP1699748B1 (pt)
JP (1) JP2007516995A (pt)
KR (1) KR20060113965A (pt)
CN (1) CN1898190A (pt)
AR (1) AR046975A1 (pt)
AT (1) ATE411272T1 (pt)
AU (1) AU2004303506A1 (pt)
BR (1) BRPI0417971A (pt)
CA (1) CA2550627A1 (pt)
DE (2) DE10360525B3 (pt)
IL (1) IL176029A0 (pt)
MX (1) MXPA06005615A (pt)
TW (1) TW200602312A (pt)
WO (1) WO2005061427A2 (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4042283A1 (de) * 1990-12-31 1992-07-02 Basf Ag Verfahren zur herstellung von 2-phenoxymethylbenzoesaeuren
JP3272819B2 (ja) * 1993-06-16 2002-04-08 協和醗酵工業株式会社 安息香酸およびニコチン酸誘導体の製造方法
US7025999B2 (en) * 2001-05-11 2006-04-11 Wm. Wrigley Jr. Company Chewing gum having prolonged sensory benefits
PL351470A1 (en) * 1999-04-28 2003-04-22 Aventis Pharma Gmbh Tri-aryl acid derivatives as ppar receptor ligands

Also Published As

Publication number Publication date
WO2005061427A2 (de) 2005-07-07
KR20060113965A (ko) 2006-11-03
WO2005061427A3 (de) 2005-10-06
CN1898190A (zh) 2007-01-17
CA2550627A1 (en) 2005-07-07
DE10360525B3 (de) 2005-08-18
AR046975A1 (es) 2006-01-04
MXPA06005615A (es) 2006-08-17
JP2007516995A (ja) 2007-06-28
TW200602312A (en) 2006-01-16
IL176029A0 (en) 2006-10-05
DE502004008297D1 (de) 2008-11-27
EP1699748A2 (de) 2006-09-13
EP1699748B1 (de) 2008-10-15
ATE411272T1 (de) 2008-10-15
AU2004303506A1 (en) 2005-07-07

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]