BRPI0418928A - composição para reduzir teor de colesterol em ovos de aves domésticas, suplemento de ração e ração de aves domésticas, ovos com baixo teor de colesterol e métodos para produção dos mesmos - Google Patents
composição para reduzir teor de colesterol em ovos de aves domésticas, suplemento de ração e ração de aves domésticas, ovos com baixo teor de colesterol e métodos para produção dos mesmosInfo
- Publication number
- BRPI0418928A BRPI0418928A BRPI0418928-0A BRPI0418928A BRPI0418928A BR PI0418928 A BRPI0418928 A BR PI0418928A BR PI0418928 A BRPI0418928 A BR PI0418928A BR PI0418928 A BRPI0418928 A BR PI0418928A
- Authority
- BR
- Brazil
- Prior art keywords
- eggs
- cholesterol
- poultry
- methods
- poultry eggs
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 20
- 235000012000 cholesterol Nutrition 0.000 title abstract 10
- 235000013601 eggs Nutrition 0.000 title abstract 9
- 244000144977 poultry Species 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000006052 feed supplement Substances 0.000 title 1
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 abstract 4
- 230000000813 microbial effect Effects 0.000 abstract 3
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 abstract 2
- VGMFHMLQOYWYHN-UHFFFAOYSA-N Compactin Natural products OCC1OC(OC2C(O)C(O)C(CO)OC2Oc3cc(O)c4C(=O)C(=COc4c3)c5ccc(O)c(O)c5)C(O)C(O)C1O VGMFHMLQOYWYHN-UHFFFAOYSA-N 0.000 abstract 1
- TUZYXOIXSAXUGO-UHFFFAOYSA-N Pravastatin Natural products C1=CC(C)C(CCC(O)CC(O)CC(O)=O)C2C(OC(=O)C(C)CC)CC(O)C=C21 TUZYXOIXSAXUGO-UHFFFAOYSA-N 0.000 abstract 1
- AJLFOPYRIVGYMJ-UHFFFAOYSA-N SJ000287055 Natural products C12C(OC(=O)C(C)CC)CCC=C2C=CC(C)C1CCC1CC(O)CC(=O)O1 AJLFOPYRIVGYMJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000871 hypocholesterolemic effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- AJLFOPYRIVGYMJ-INTXDZFKSA-N mevastatin Chemical compound C([C@H]1[C@@H](C)C=CC2=CCC[C@@H]([C@H]12)OC(=O)[C@@H](C)CC)C[C@@H]1C[C@@H](O)CC(=O)O1 AJLFOPYRIVGYMJ-INTXDZFKSA-N 0.000 abstract 1
- BOZILQFLQYBIIY-UHFFFAOYSA-N mevastatin hydroxy acid Natural products C1=CC(C)C(CCC(O)CC(O)CC(O)=O)C2C(OC(=O)C(C)CC)CCC=C21 BOZILQFLQYBIIY-UHFFFAOYSA-N 0.000 abstract 1
- TUZYXOIXSAXUGO-PZAWKZKUSA-N pravastatin Chemical compound C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 TUZYXOIXSAXUGO-PZAWKZKUSA-N 0.000 abstract 1
- 229960002965 pravastatin Drugs 0.000 abstract 1
- 239000013589 supplement Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Birds (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pyrane Compounds (AREA)
Abstract
COMPOSIçãO PARA REDUZIR TEOR DE COLESTEROL EM OVOS DE AVES DOMéSTICAS, SUPLEMENTO DE RAçãO E RAçãO DE AVES DOMéSTICAS, OVOS COM BAIXO TEOR DE COLESTEROL E MéTODOS PARA PRODUçãO DOS MESMOS. A presente invenção refere-se a composições e métodos para produzir ovos de aves domésticas com baixo teor de colesterol usando compostos hipocolesterolêmicos, suplementos para redução do colesterol, e rações destes. Preferivelmente, esta invenção fornece estatinas microbianas sem o grupo metila em C6, como mostrado na fórmula V, de modo a produzir ovos de aves domésticas com baixo teor de colesterol. A invenção permite a produção de ovos de aves domésticas com baixo teor de colesterol sem a redução concomitante da produção de ovos fornecendo-se estatinas microbianas, compactina e pravastatina assim como seus derivados, como componentes para redução do colesterol. Esta invenção também fornece métodos para produzir ovos de aves domésticas com baixo teor de colesterol sem o aumento muito grande do custo da produção visto que a quantidade eficaz da composição para redução de colesterol contendo estatina microbiana custa 1/20 a 1/4 daquela da estatina sintética.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020040060480A KR100637762B1 (ko) | 2004-07-30 | 2004-07-30 | 저콜레스테롤 란을 생산하기 위한 가금류용 사료첨가제 및 이를 이용한 저콜레스테롤 란의 생산방법 |
| PCT/KR2004/003247 WO2006011702A1 (en) | 2004-07-30 | 2004-12-10 | Cholesterol lowering supplement and low cholesterol egg produced by using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0418928A true BRPI0418928A (pt) | 2007-11-27 |
Family
ID=35786421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0418928-0A BRPI0418928A (pt) | 2004-07-30 | 2004-12-10 | composição para reduzir teor de colesterol em ovos de aves domésticas, suplemento de ração e ração de aves domésticas, ovos com baixo teor de colesterol e métodos para produção dos mesmos |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090181150A1 (pt) |
| EP (1) | EP1778218A4 (pt) |
| JP (1) | JP2008508259A (pt) |
| KR (1) | KR100637762B1 (pt) |
| CN (1) | CN1993122B (pt) |
| BR (1) | BRPI0418928A (pt) |
| WO (1) | WO2006011702A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2425961A1 (en) | 2010-09-07 | 2012-03-07 | Latexco NV | Functionalized latex based foam |
| US9168277B2 (en) | 2013-03-14 | 2015-10-27 | Auburn University | Nutraceutical compositions produced from co-products of corn or milo ethanol fermentation and methods of making and using thereof |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4049495A (en) * | 1974-06-07 | 1977-09-20 | Sankyo Company Limited | Physiologically active substances and fermentative process for producing the same |
| JPS5612114B2 (pt) * | 1974-06-07 | 1981-03-18 | ||
| DE2748825C2 (de) * | 1976-11-02 | 1986-11-27 | Sankyo Co., Ltd., Tokio/Tokyo | Substituierte 3,5-Dihydroxyheptansäurederivate und diese enthaltende Arzneimittel gegen Hyperlipämie |
| JPS5929209B2 (ja) * | 1977-08-10 | 1984-07-19 | 三共株式会社 | 家禽の低コレステロ−ル卵の生産法 |
| US4231938A (en) * | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
| US4444784A (en) * | 1980-08-05 | 1984-04-24 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| DK149080C (da) * | 1980-06-06 | 1986-07-28 | Sankyo Co | Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre |
| US4450171A (en) * | 1980-08-05 | 1984-05-22 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| JPS5889191A (ja) * | 1981-11-20 | 1983-05-27 | Sankyo Co Ltd | ３−ヒドロキシ−ｍｌ−２３６ｂ誘導体の製造法 |
| US4739073A (en) * | 1983-11-04 | 1988-04-19 | Sandoz Pharmaceuticals Corp. | Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof |
| US5179013A (en) * | 1987-02-02 | 1993-01-12 | Sankyo Company, Limited | Cytochrome P-450 enzymes |
| FI94339C (fi) * | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
| DE4309553A1 (de) * | 1993-03-24 | 1994-09-29 | Bayer Ag | Verfahren zur Herstellung von 3R,5S-(+)-Natrium-erythro-(E)-7-(4-(4-flurophenyl)-2,6-diisopropyl-5-methoxymethyl-pyrid-3-yl)-3,5-dihydroxy-hept-6-enoat |
| US5942423A (en) * | 1995-06-07 | 1999-08-24 | Massachusetts Institute Of Technology | Conversion of compactin to pravastatin by actinomadura |
| NZ280074A (en) * | 1995-09-21 | 1997-05-26 | Apotex Inc Substituted For Sco | "compactin" produced by penicillium adametzioides g smith |
| US6177121B1 (en) | 1997-09-29 | 2001-01-23 | Purdue Research Foundation | Composition and method for producing low cholesterol eggs |
| DE19835850A1 (de) * | 1998-08-07 | 2000-02-10 | Basf Ag | Verwendung von Hemmstoffen der HMG-CoA-Reduktase zur Senkung des Cholesteringehaltes in Geflügelei |
| US6323021B1 (en) * | 1999-01-15 | 2001-11-27 | Industrial Technology Research Institute | Mutant strain of penicillium citrinum and use thereof for preparation of compactin |
| US6682913B1 (en) * | 1999-02-03 | 2004-01-27 | Institute For Drug Research Ltd. | Microbial process for preparing pravastatin |
| KR100379075B1 (en) * | 2002-03-07 | 2003-04-08 | Jinis Biopharmaceuticals Co | Method for producing low cholesterol animal food product and food product therefrom |
| WO2004030632A2 (en) | 2002-10-03 | 2004-04-15 | Sylvan Bioproducts, Inc. | Monascus derived poultry feed and by-products |
| KR20040050645A (ko) * | 2002-12-10 | 2004-06-16 | 한영환 | 산란계용 사료 및 동 사료를 급여한 산란계로부터얻어지는 콜레스테롤이 감소된 계란 |
-
2004
- 2004-07-30 KR KR1020040060480A patent/KR100637762B1/ko not_active Expired - Fee Related
- 2004-12-10 JP JP2007523457A patent/JP2008508259A/ja active Pending
- 2004-12-10 EP EP04808378A patent/EP1778218A4/en not_active Withdrawn
- 2004-12-10 BR BRPI0418928-0A patent/BRPI0418928A/pt not_active Application Discontinuation
- 2004-12-10 WO PCT/KR2004/003247 patent/WO2006011702A1/en not_active Ceased
- 2004-12-10 CN CN200480043715XA patent/CN1993122B/zh not_active Expired - Fee Related
- 2004-12-10 US US11/658,929 patent/US20090181150A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR100637762B1 (ko) | 2006-10-23 |
| EP1778218A1 (en) | 2007-05-02 |
| JP2008508259A (ja) | 2008-03-21 |
| EP1778218A4 (en) | 2009-04-22 |
| WO2006011702A1 (en) | 2006-02-02 |
| US20090181150A1 (en) | 2009-07-16 |
| KR20060011578A (ko) | 2006-02-03 |
| CN1993122B (zh) | 2011-04-13 |
| CN1993122A (zh) | 2007-07-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |
|
| B15K | Others concerning applications: alteration of classification |
Free format text: PROCEDIMENTO AUTOMATICO DE RECLASSIFICACAO. AS CLASSIFICACOES IPC ANTERIORES ERAM: A61K 31/365; A23K 1/16; A61P 3/00. Ipc: A61K 31/365 (2006.01), A23K 20/121 (2016.01), A23K Ipc: A61K 31/365 (2006.01), A23K 20/121 (2016.01), A23K |