BRPI0501384A8 - processo de validação estatística de amostras e analítico de células endoteliais da córnea - Google Patents

processo de validação estatística de amostras e analítico de células endoteliais da córnea

Info

Publication number
BRPI0501384A8
BRPI0501384A8 BRPI0501384A BRPI0501384A BRPI0501384A8 BR PI0501384 A8 BRPI0501384 A8 BR PI0501384A8 BR PI0501384 A BRPI0501384 A BR PI0501384A BR PI0501384 A BRPI0501384 A BR PI0501384A BR PI0501384 A8 BRPI0501384 A8 BR PI0501384A8
Authority
BR
Brazil
Prior art keywords
statistical
demonstrate
endothelial cells
validity
medical
Prior art date
Application number
BRPI0501384A
Other languages
English (en)
Inventor
Cesar Abib Fernando
Original Assignee
Cesar Abib Fernando
Ronialci De Godois
Yoshiaki Hara
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cesar Abib Fernando, Ronialci De Godois, Yoshiaki Hara filed Critical Cesar Abib Fernando
Priority to BRPI0501384A priority Critical patent/BRPI0501384A8/pt
Priority to CN2005800501697A priority patent/CN101203185B/zh
Priority to US11/911,502 priority patent/US7957915B2/en
Priority to PCT/BR2005/000144 priority patent/WO2006108250A1/en
Priority to EP05764574A priority patent/EP1874193A4/en
Priority to JP2008505698A priority patent/JP4981028B2/ja
Priority to CA2604371A priority patent/CA2604371C/en
Publication of BRPI0501384A publication Critical patent/BRPI0501384A/pt
Publication of BRPI0501384A8 publication Critical patent/BRPI0501384A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/13—Ophthalmic microscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Eye Examination Apparatus (AREA)
  • Prostheses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"processo de validação estatística de amostras e analítico de células endoteliais da córnea ". refere-se a patente de invenção de processo complementar ao processo realizado por aparelhos de microscopia especular de córnea, através de incorporação de informações obtidas por aparelhos atualmente existentes, inferindo-lhes validade estatística e conseqüentemente médica para melhor definir diagnósticos e condutas clínicas e/ou cirúrgicas, elevando a qualidade deste procedimento a um novo patamar de confiabilidade médica, com as vantagens de evitar que exames sejam realizados de forma inadequada e conseqüentemente considerados válidos, contribuir para a precisão do diagnóstico, conferir validade ou invalidade de exames já realizados, orientar a rotina de banco de olhos na seleção e classificação da viabilidade da córnea doada, aproveitar os equipamentos em uso no mundo para aprimorar seus próprios resultados e evitar sua obsolescência, identificar os exames realizados com amostragem não significativa, demonstrar, de forma gráfica (réguas estatístico-analíticas) e numérica, os valores das variáveis mensuradas no olho em exame, comparativamente aos valores médios de pessoas normais na faixa etária do paciente, demonstrar ao médico os casos de córnea com risco para procedimentos clínicos ou cirúrgicos, auxiliando no planejamento da conduta médica perante um doença, demonstrar adicionalmente o erro relativo referente ao tipo de amostra selecionada e calculada, demonstrar, para um mesmo cirurgião, a perda de células endoteliais inerentes a diferente técnicas e tipos de cirurgias intra-ocular (fator cirurgião) e permitir que os médicos que recebem o exame de microscopia especular em seu consultório realize análise da validade amostral obtida antes de valorizar os resultados da celularidade e morfologia endotelial.
BRPI0501384A 2005-04-15 2005-04-15 processo de validação estatística de amostras e analítico de células endoteliais da córnea BRPI0501384A8 (pt)

Priority Applications (7)

Application Number Priority Date Filing Date Title
BRPI0501384A BRPI0501384A8 (pt) 2005-04-15 2005-04-15 processo de validação estatística de amostras e analítico de células endoteliais da córnea
CN2005800501697A CN101203185B (zh) 2005-04-15 2005-07-29 角膜内皮细胞分析样本的统计学检验方法
US11/911,502 US7957915B2 (en) 2005-04-15 2005-07-29 Process of statistic validation of corneal endothelial cells analysed samples
PCT/BR2005/000144 WO2006108250A1 (en) 2005-04-15 2005-07-29 Process of statistic validation of corneal endothelium cells analysed samples
EP05764574A EP1874193A4 (en) 2005-04-15 2005-07-29 METHOD FOR THE STATISTICAL VALIDATION OF SCREENS ANALYZED FROM CELL ENDOTHELIUM CELLS
JP2008505698A JP4981028B2 (ja) 2005-04-15 2005-07-29 角膜内皮細胞分析試料の統計的有効性検証の方法
CA2604371A CA2604371C (en) 2005-04-15 2005-07-29 Process of statistic validation of corneal endothelium cells analysed samples

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0501384A BRPI0501384A8 (pt) 2005-04-15 2005-04-15 processo de validação estatística de amostras e analítico de células endoteliais da córnea

Publications (2)

Publication Number Publication Date
BRPI0501384A BRPI0501384A (pt) 2006-12-12
BRPI0501384A8 true BRPI0501384A8 (pt) 2017-02-14

Family

ID=37086543

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0501384A BRPI0501384A8 (pt) 2005-04-15 2005-04-15 processo de validação estatística de amostras e analítico de células endoteliais da córnea

Country Status (7)

Country Link
US (1) US7957915B2 (pt)
EP (1) EP1874193A4 (pt)
JP (1) JP4981028B2 (pt)
CN (1) CN101203185B (pt)
BR (1) BRPI0501384A8 (pt)
CA (1) CA2604371C (pt)
WO (1) WO2006108250A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8403919B2 (en) 2007-06-05 2013-03-26 Alcon Refractivehorizons, Inc. Nomogram computation and application system and method for refractive laser surgery
US8628572B2 (en) * 2009-02-26 2014-01-14 Wake Forest University Health Sciences Corneal endothelial scaffolds and methods of use
CN104462739B (zh) * 2014-03-13 2017-08-11 中国科学院遥感与数字地球研究所 一种适用于大范围多尺度卫星遥感数据反演的生态环境参数地面采样方法
JP6464569B2 (ja) * 2014-05-19 2019-02-06 株式会社ニデック 角膜内皮細胞解析プログラム
CN119784748B (zh) * 2025-03-09 2025-05-02 中国民用航空飞行学院 一种基于影像的图像处理分析系统及方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0493386B1 (de) * 1990-07-23 1995-05-10 Bruker Analytische Messtechnik GmbH Verfahren und vorrichtung zur ermittlung von chemischen zuständen von lebendem, tierischem oder menschlichem gewebe unter verwendung von magnetischer resonanz
JP3265044B2 (ja) * 1993-03-23 2002-03-11 株式会社コーナン・メディカル 角膜内皮細胞形態決定方法
JPH0737062A (ja) * 1993-07-21 1995-02-07 Topcon Corp 医用画像処理システム
JPH07213491A (ja) * 1994-02-01 1995-08-15 Topcon Corp 角膜内皮細胞密度計測装置
JPH09313442A (ja) * 1996-06-03 1997-12-09 Topcon Corp 角膜内皮細胞計測装置
KR20010108196A (ko) * 1999-02-10 2001-12-07 옥스포드 내쳐럴 프로덕츠 피엘씨 의약용 식물 제품의 품질관리 및 표준화 방법
JP2001314374A (ja) * 2000-05-09 2001-11-13 Topcon Corp 角膜内皮細胞測定装置
US6523954B1 (en) * 2000-11-21 2003-02-25 Iscreen, Llc System and method for eye screening
JP2002191560A (ja) * 2000-12-27 2002-07-09 Konan Medical Inc 角膜内皮細胞解析サービス方法及びシステム
JP3469872B2 (ja) * 2000-12-27 2003-11-25 株式会社コーナン・メディカル 角膜内皮細胞解析システム
FR2819591A1 (fr) * 2001-01-12 2002-07-19 Agronomique Inst Nat Rech Procede de discrimination avec reperage et/ou identification de situations de perturbations biologiques par spectrometrie et reconnaissance de forme
JP2003265413A (ja) * 2002-03-18 2003-09-24 Konan Medical Inc 角膜内皮細胞解析装置および角膜内皮細胞像の判定方法
CN1139898C (zh) * 2002-03-25 2004-02-25 北京工业大学 基于k-均值聚类及信息融合的角膜病灶图像分割方法

Also Published As

Publication number Publication date
US20080189050A1 (en) 2008-08-07
CA2604371C (en) 2013-06-18
JP2008535590A (ja) 2008-09-04
WO2006108250A1 (en) 2006-10-19
CN101203185A (zh) 2008-06-18
CN101203185B (zh) 2012-05-23
EP1874193A4 (en) 2009-12-16
CA2604371A1 (en) 2006-10-19
JP4981028B2 (ja) 2012-07-18
US7957915B2 (en) 2011-06-07
BRPI0501384A (pt) 2006-12-12
EP1874193A1 (en) 2008-01-09

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Legal Events

Date Code Title Description
B65X Notification of requirement for priority examination of patent application
B65Y Grant of priority examination of the patent application (request complies with dec. 132/06 of 20061117)
B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: A61B 3/13

Ipc: G06F 19/00 (2011.01), A61F 9/00 (2006.01), A61B 10

B03H Publication of an application: rectification [chapter 3.8 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]