BRPI0501708A - transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device - Google Patents

transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device

Info

Publication number
BRPI0501708A
BRPI0501708A BRPI0501708A BRPI0501708A BR PI0501708 A BRPI0501708 A BR PI0501708A BR PI0501708 A BRPI0501708 A BR PI0501708A BR PI0501708 A BRPI0501708 A BR PI0501708A
Authority
BR
Brazil
Prior art keywords
transdermal
slow
producing
release device
excess
Prior art date
Application number
Other languages
Portuguese (pt)
Inventor
Jean Marc Millet
Original Assignee
Jean Marc Millet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jean Marc Millet filed Critical Jean Marc Millet
Priority to BRPI0501708 priority Critical patent/BRPI0501708A/en
Priority to PCT/BR2006/000090 priority patent/WO2006119598A2/en
Publication of BRPI0501708A publication Critical patent/BRPI0501708A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

DIPOSITIVO DE LIBERAçãO LENTA POR PROCESSO TRANSDéRMICO DE UM MEDICAMENTO CONTRA O EXECESSO DE COLESTEROL E MéTODO DE PRODUçãO DE UM DISPOSITIVO TRANSDéRMICO,o qual é caracterizado por prever um dispositivo bi-laminar,leberação lenta transdérmica constituída de uma matriz macromolecular flexível (2) de uma espessura de 0,15 0, 6 cm e de uma superfície entre 10 e 100 cm quadrados e apresentando de um lado um revestimento posterior (1), permitindo uma redução considerável (mais de 15 vezes) das doses diárias a serem asministradas no tratamento do excesso de colesterol,a matriz macromolecular contendo e liberando de maneira contínua durante um período de 1 a 4 meses 0, 05 a 18% por dias de seu peso total em ómega 3 e/ou estatina,pela superfície em contato com a pele do paciente sem precisar aderir de forma fixa e permanente à pele do mesmo.SLOW RELEASE DEVICE BY TRANSDERMAL PROCESS OF A MEDICINAL PRODUCT AGAINST EXCESS OF CHOLESTEROL AND PRODUCTION METHOD OF A TRANSDERMAL DEVICE, which is characterized by providing a bi-laminar device, slow transdermal leberation consisting of a flexible macromolecular matrix (2) thickness of 0.15 0.6 cm and a surface area of 10 to 100 cm square and having on one side a backing (1), allowing a considerable reduction (more than 15 times) of the daily doses to be administered in the treatment of excess cholesterol, the macromolecular matrix containing and releasing continuously over a period of 1 to 4 months 0, 05 to 18% per day of its total weight in omega 3 and / or statin, by the surface in contact with the patient's skin without sticking permanently to the skin of the same.

BRPI0501708 2005-05-10 2005-05-10 transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device BRPI0501708A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BRPI0501708 BRPI0501708A (en) 2005-05-10 2005-05-10 transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device
PCT/BR2006/000090 WO2006119598A2 (en) 2005-05-10 2006-05-10 Transdermal device for the slow delivery of an omega-3-fatty acid, optionally in combination with a hmg coa reductase inhibitor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0501708 BRPI0501708A (en) 2005-05-10 2005-05-10 transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device

Publications (1)

Publication Number Publication Date
BRPI0501708A true BRPI0501708A (en) 2007-05-02

Family

ID=37396906

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0501708 BRPI0501708A (en) 2005-05-10 2005-05-10 transdermal slow-release device for an excess cholesterol drug and method of producing a transdermal device

Country Status (2)

Country Link
BR (1) BRPI0501708A (en)
WO (1) WO2006119598A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2940116B1 (en) * 2008-12-22 2012-07-06 Philippe Perovitch FORMULATION FOR THE ADMINISTRATION OF HYPOLIPEMIC BY ORAL TRANS-MUCOSAL
US9107983B2 (en) 2010-10-27 2015-08-18 Warsaw Orthopedic, Inc. Osteoconductive matrices comprising statins
US8877221B2 (en) 2010-10-27 2014-11-04 Warsaw Orthopedic, Inc. Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same
US9308190B2 (en) 2011-06-06 2016-04-12 Warsaw Orthopedic, Inc. Methods and compositions to enhance bone growth comprising a statin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2548021B1 (en) * 1983-06-29 1986-02-28 Dick P R PROLONGED AND CONTINUOUS DERMAL PHARMACEUTICAL COMPOSITIONS BASED ON ESSENTIAL FATTY ACIDS
JP4062639B2 (en) * 1996-12-23 2008-03-19 日本水産株式会社 Skin preparation
DE10056010A1 (en) * 2000-11-11 2002-05-16 Beiersdorf Ag Well tolerated plaster for controlled delivery of cosmetic skin care agents, having active agent-containing matrix comprising polyisobutylene, amorphous poly-alpha-olefin and optionally filler

Also Published As

Publication number Publication date
WO2006119598A2 (en) 2006-11-16
WO2006119598A3 (en) 2007-03-01

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired