BRPI0507718A - derivados de pirazolina úteis para o tratamento de cáncer - Google Patents

derivados de pirazolina úteis para o tratamento de cáncer

Info

Publication number
BRPI0507718A
BRPI0507718A BRPI0507718-4A BRPI0507718A BRPI0507718A BR PI0507718 A BRPI0507718 A BR PI0507718A BR PI0507718 A BRPI0507718 A BR PI0507718A BR PI0507718 A BRPI0507718 A BR PI0507718A
Authority
BR
Brazil
Prior art keywords
cancer
treatment
compounds
cancer treatment
derivatives useful
Prior art date
Application number
BRPI0507718-4A
Other languages
English (en)
Inventor
Rosa Cuberes Altisen
Jordi Frigola Constansa
Ramon Mangues Bafalluy
Isolda Casanova Rigal
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES200400362A external-priority patent/ES2238923B1/es
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of BRPI0507718A publication Critical patent/BRPI0507718A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

DERIVADOS DE PIRAZOLINA úTEIS PARA O TRATAMENTO DE CáNCER A presente invenção relaciona-se a novos compostos de pirazolina substituídos, composições farmacêuticas contendo tais compostos e o uso destes compostos para o tratamento de câncer, particularmente para o tratamento de câncer cerebral, câncer nos ossos, cãncer labial, câncer da boca, câncer esofageal, câncer de estomago, câncer de fígado, câncer de bexiga, cãncer de pâncreas, câncer de óvario, cârcer cervical, cãncer de pulmão, câncer de mama, cãncer de pele, especialmente para o tratamento de cãncer de cólon e/ou câncer de intestino e/ou câncer de próstata.
BRPI0507718-4A 2004-02-16 2005-02-16 derivados de pirazolina úteis para o tratamento de cáncer BRPI0507718A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200400362A ES2238923B1 (es) 2004-02-16 2004-02-16 Nuevos derivados pirazolinicos sustituidos.
US10/804,695 US20050182119A1 (en) 2004-02-16 2004-03-19 Substituted pyrazoline derivatives
PCT/EP2005/001656 WO2005077910A1 (en) 2004-02-16 2005-02-16 Pyrazoline derivatives useful for the treatment of cancer

Publications (1)

Publication Number Publication Date
BRPI0507718A true BRPI0507718A (pt) 2007-07-03

Family

ID=34863166

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507718-4A BRPI0507718A (pt) 2004-02-16 2005-02-16 derivados de pirazolina úteis para o tratamento de cáncer

Country Status (9)

Country Link
EP (1) EP1718618A1 (pt)
JP (1) JP2007522180A (pt)
KR (1) KR20070044799A (pt)
AU (1) AU2005212833A1 (pt)
BR (1) BRPI0507718A (pt)
CA (1) CA2556478A1 (pt)
NO (1) NO20064185L (pt)
RU (1) RU2006133150A (pt)
WO (1) WO2005077910A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2304989C2 (ru) * 2005-08-26 2007-08-27 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО "НижГМА Росздрава") Способ комбинированного лечения операбельного рака желудка
JP2008308473A (ja) * 2007-06-18 2008-12-25 Japan Health Science Foundation 癌治療剤
CN101735150B (zh) * 2009-12-16 2011-12-28 南京大学 一类含有吡唑环的硫脲类衍生物及其制法和用途
CN101759695B (zh) * 2009-12-30 2011-09-14 南京大学 一类含有吡唑环的噻唑类衍生物及其制法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100796851B1 (ko) * 1999-06-16 2008-01-22 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 사이클록시게나아제-2의 억제제로서 1-(4-설파밀아릴)-3-치환형-5-아릴-2-피라졸린
ES2174757B1 (es) * 2001-04-06 2003-11-01 Esteve Labor Dr Empleo de derivados de firazolinas en la elaboracion de un medicamentopara la prevencion y/o el tratamiento de enfermedades proliferativas celulares.

Also Published As

Publication number Publication date
CA2556478A1 (en) 2005-08-25
RU2006133150A (ru) 2008-04-10
JP2007522180A (ja) 2007-08-09
AU2005212833A1 (en) 2005-08-25
WO2005077910A1 (en) 2005-08-25
KR20070044799A (ko) 2007-04-30
NO20064185L (no) 2006-11-13
EP1718618A1 (en) 2006-11-08

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A(S) 4A, 5A E 6A ANUIDADE(S)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2099 DE 29/03/2011.