BRPI0509887A - imobilização não-covalente de moléculas indicadoras - Google Patents

imobilização não-covalente de moléculas indicadoras

Info

Publication number
BRPI0509887A
BRPI0509887A BRPI0509887-4A BRPI0509887A BRPI0509887A BR PI0509887 A BRPI0509887 A BR PI0509887A BR PI0509887 A BRPI0509887 A BR PI0509887A BR PI0509887 A BRPI0509887 A BR PI0509887A
Authority
BR
Brazil
Prior art keywords
indicator molecules
covalent immobilization
molecules
immobilization
sensors
Prior art date
Application number
BRPI0509887-4A
Other languages
English (en)
Inventor
Arthur E Colvin Jr
Carrie R Lorenz
Original Assignee
Sensors For Med & Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sensors For Med & Science Inc filed Critical Sensors For Med & Science Inc
Publication of BRPI0509887A publication Critical patent/BRPI0509887A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/14517—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for sweat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A61B5/14735—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter comprising an immobilised reagent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

IMOBILIZAçãO NãO-COVALENTE DE MOLéCULAS INDICADORAS. A invenção refere-se a métodos de imobilização, em particular para imobilizar moléculas indicadoras sobre suportes tais como sensores e a sensores que possuem aquelas moléculas imobilizadas sobre sua superfície. A imobilização não-covalente de moléculas indicadoras macromoleculares sobre aqueles suportes através de redes interpenetrantes de entrelaçamento mecânico com polímeros na superfície de um suporte e através de ligação iónica por meio de porções carregadas de moléculas indicadoras e grupos iónicos sobre a superfície do suporte é descritas.
BRPI0509887-4A 2004-04-13 2005-04-07 imobilização não-covalente de moléculas indicadoras BRPI0509887A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/822,670 US7713745B2 (en) 2004-04-13 2004-04-13 Non-covalent immobilization of indicator molecules
PCT/US2005/011654 WO2005100981A1 (en) 2004-04-13 2005-04-07 Non-covalent immobilization of indicator molecules

Publications (1)

Publication Number Publication Date
BRPI0509887A true BRPI0509887A (pt) 2007-10-09

Family

ID=34965691

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509887-4A BRPI0509887A (pt) 2004-04-13 2005-04-07 imobilização não-covalente de moléculas indicadoras

Country Status (11)

Country Link
US (1) US7713745B2 (pt)
EP (1) EP1740938B1 (pt)
JP (1) JP5063342B2 (pt)
KR (1) KR101157604B1 (pt)
CN (1) CN1942764B (pt)
AU (1) AU2005233991B2 (pt)
BR (1) BRPI0509887A (pt)
CA (1) CA2563404C (pt)
MX (1) MXPA06011802A (pt)
TW (1) TWI393761B (pt)
WO (1) WO2005100981A1 (pt)

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Publication number Priority date Publication date Assignee Title
US8029765B2 (en) * 2003-12-24 2011-10-04 Masimo Laboratories, Inc. SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
GB2447965B (en) * 2007-03-29 2011-12-07 Fiberlogix Ltd A porous IPN polymer structure for use in chemical sensing applications
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
CN102575023A (zh) * 2009-07-31 2012-07-11 惠普发展公司，有限责任合伙企业 发射半-互穿聚合物网络
JP6084172B2 (ja) * 2011-03-15 2017-02-22 センセオニクス，インコーポレーテッド 酸化感受性材料の統合的な触媒による保護
US11109779B2 (en) 2012-12-28 2021-09-07 Senseonics, Incorporated Chemical modification of analyte permeable membrane for enhanced oxidative stability
MX2015008531A (es) 2012-12-28 2016-02-10 Senseonics Inc Sistema de membrana permeable a analito para estabilidad oxidativa y óptica.
US9498156B2 (en) 2013-05-17 2016-11-22 Senseonics, Incorporated Opacity consistent polymer graft for optical sensor
US9963556B2 (en) 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
WO2016014800A1 (en) 2014-07-23 2016-01-28 Senseonics, Incorporated Fabrication of a fluorescent material for sensing an analyte
CN109187449B (zh) * 2018-07-26 2021-06-22 中认英泰检测技术有限公司 环境响应型智能传感装置及其制备方法与应用
HUP1900197A2 (hu) * 2019-06-04 2020-12-28 Moow Farm Kft Új polimer gél hordozó polimer indikátor kombináció
WO2021081404A1 (en) 2019-10-25 2021-04-29 Cercacor Laboratories, Inc. Indicator compounds, devices comprising indicator compounds, and methods of making and using the same

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US5217491A (en) 1990-12-27 1993-06-08 American Cyanamid Company Composite intraocular lens
US5356417A (en) 1992-10-09 1994-10-18 United States Surgical Corporation Absorbable sternum closure buckle
GB2284809B (en) 1993-11-07 1998-04-29 Japan Res Dev Corp A fluorescent phenylboronic acid suitable for use in the detection of saccharides
US5517313A (en) 1995-02-21 1996-05-14 Colvin, Jr.; Arthur E. Fluorescent optical sensor
US6011936A (en) * 1995-05-16 2000-01-04 Canon Kabushiki Kaisha Image forming apparatus having recovery process for jammed sheets
EP0862648B1 (en) 1995-11-22 2004-10-06 Medtronic MiniMed, Inc. Detection of biological molecules using chemical amplification and optical sensors
US5910661A (en) 1997-05-13 1999-06-08 Colvin, Jr.; Arthur E. Flourescence sensing device
US5894351A (en) 1997-05-13 1999-04-13 Colvin, Jr.; Arthur E. Fluorescence sensing device
US6001936A (en) 1997-10-24 1999-12-14 3M Innovative Properties Company Dye enhanced durability through controlled dye environment
TWI227323B (en) 1998-03-11 2005-02-01 Sensors For Med & Science Inc Detection of analytes by fluorescent lanthanide metal chelate complexes containing substituted ligands
US6304766B1 (en) 1998-08-26 2001-10-16 Sensors For Medicine And Science Optical-based sensing devices, especially for in-situ sensing in humans
JP4689825B2 (ja) 1998-08-26 2011-05-25 センサーズ・フォー・メデセン・アンド・サイエンス・インコーポレーテッド 光学式検知装置
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US6653141B2 (en) * 2000-12-05 2003-11-25 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing method and device
US6627177B2 (en) * 2000-12-05 2003-09-30 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof
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Also Published As

Publication number Publication date
KR20070006840A (ko) 2007-01-11
EP1740938A1 (en) 2007-01-10
US7713745B2 (en) 2010-05-11
TW200602460A (en) 2006-01-16
MXPA06011802A (es) 2006-12-15
WO2005100981A1 (en) 2005-10-27
CN1942764A (zh) 2007-04-04
US20050227242A1 (en) 2005-10-13
KR101157604B1 (ko) 2012-07-06
AU2005233991B2 (en) 2011-10-20
EP1740938B1 (en) 2017-05-17
CA2563404C (en) 2014-07-08
JP2007532901A (ja) 2007-11-15
TWI393761B (zh) 2013-04-21
AU2005233991A1 (en) 2005-10-27
CA2563404A1 (en) 2005-10-27
CN1942764B (zh) 2011-07-13
JP5063342B2 (ja) 2012-10-31

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]