BRPI0510136A - steroids with androgenic effect - Google Patents

steroids with androgenic effect

Info

Publication number
BRPI0510136A
BRPI0510136A BRPI0510136-0A BRPI0510136A BRPI0510136A BR PI0510136 A BRPI0510136 A BR PI0510136A BR PI0510136 A BRPI0510136 A BR PI0510136A BR PI0510136 A BRPI0510136 A BR PI0510136A
Authority
BR
Brazil
Prior art keywords
androgenic
steroids
effect
androgenic effect
steroidal
Prior art date
Application number
BRPI0510136-0A
Other languages
Portuguese (pt)
Inventor
Ralf Wyrwa
Peter Droescher
Sven Ring
Walter Elger
Birgitt Schneider
Alexander Hillisch
Gudrun Reddersen
Original Assignee
Schering Aktiengellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengellschaft filed Critical Schering Aktiengellschaft
Publication of BRPI0510136A publication Critical patent/BRPI0510136A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

PRODROGAS ESTERóIDES COM EFEITO ANDROGêNICO. A presente invenção refere-se a prodrogas esteroidais com efeito androgênico da fórmula geral (I), nas quais o grupo Z está ligado ao esteróide, a composições farmacêuticas, que contêm esses compostos, bem como ao uso dos mesmos para produção de medicamentos com efeito androgênico.STEROID PRODUCTS WITH ANDROGENIC EFFECT. The present invention relates to androgenic steroidal prodrugs of the general formula (I), in which the group Z is attached to the steroid, to pharmaceutical compositions containing such compounds, as well as to their use for the production of medicaments with steroidal effect. androgenic.

BRPI0510136-0A 2004-05-21 2005-05-10 steroids with androgenic effect BRPI0510136A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004025986A DE102004025986A1 (en) 2004-05-21 2004-05-21 Steroid prodrugs with androgenic effects
PCT/EP2005/005256 WO2005113575A1 (en) 2004-05-21 2005-05-10 Steroid prodrugs with androgenic effect

Publications (1)

Publication Number Publication Date
BRPI0510136A true BRPI0510136A (en) 2007-10-02

Family

ID=34968657

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510136-0A BRPI0510136A (en) 2004-05-21 2005-05-10 steroids with androgenic effect

Country Status (22)

Country Link
EP (1) EP1747229A1 (en)
JP (1) JP2007538026A (en)
CN (1) CN1993375A (en)
AR (1) AR049547A1 (en)
AU (1) AU2005245568A1 (en)
BR (1) BRPI0510136A (en)
CA (1) CA2564963A1 (en)
CR (1) CR8785A (en)
DE (1) DE102004025986A1 (en)
EA (1) EA200602049A1 (en)
EC (1) ECSP067028A (en)
GT (1) GT200500122A (en)
IL (1) IL179293A0 (en)
MX (1) MXPA06013469A (en)
NO (1) NO20065885L (en)
PA (1) PA8633601A1 (en)
PE (1) PE20060271A1 (en)
SV (1) SV2006002123A (en)
TW (1) TW200613317A (en)
UY (1) UY28911A1 (en)
WO (1) WO2005113575A1 (en)
ZA (1) ZA200610769B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10027887A1 (en) 2000-05-31 2001-12-13 Jenapharm Gmbh Compounds with a sulfonamide group and pharmaceutical compositions containing these compounds
US7534780B2 (en) 2004-05-21 2009-05-19 Bayer Schering Pharma Aktiengesellschaft Estradiol prodrugs
DE102005057224A1 (en) * 2005-11-29 2007-05-31 Bayer Schering Pharma Ag New 9-alpha substituted estratriene derivatives esterified with a sulfamoylphenyl-substituted acid residue, are prodrugs useful as carboanhydrase inhibitors for treating estrogen deficiency disorders
DE102005057408A1 (en) * 2005-11-30 2007-05-31 Bayer Schering Pharma Ag New sulfamoylsulfonate prodrugs e.g. useful for protecting red blood cells from attack by parasites or for hormone replacement therapy, female fertility control or treating hormone-associated diseases
CN101708338B (en) * 2008-12-26 2014-06-04 中国人民解放军军事医学科学院放射与辐射医学研究所 Prodrug containing sterides structures and high dispersion preparation thereof
CN102964417A (en) * 2012-11-30 2013-03-13 华中药业股份有限公司 Synthetic method of 17-hydroxy tetrahydropyran ether steroid
CN107556258B (en) * 2017-08-22 2021-06-04 湖北江田精密化学有限公司 Preparation method of 4-amino-2-chloro-5 (1H-tetrazolyl-5) benzenesulfonamide
EP3533619A1 (en) * 2018-03-02 2019-09-04 Basf Se Heat sensitive recording material and color developer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH545316A (en) * 1970-07-17 1973-12-15 Hoffmann La Roche Process for the preparation of acyl derivatives
US5001234A (en) * 1987-04-16 1991-03-19 The Upjohn Company Cyclic hydrocarbons with an aminoalkyl sidechain
US5571933A (en) * 1994-11-17 1996-11-05 Duquesne University Of The Holy Ghost Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use
DE19712488A1 (en) * 1997-03-25 1998-10-01 Knoell Hans Forschung Ev Steroid sulfamates, processes for their preparation and use thereof
DE10027887A1 (en) * 2000-05-31 2001-12-13 Jenapharm Gmbh Compounds with a sulfonamide group and pharmaceutical compositions containing these compounds

Also Published As

Publication number Publication date
GT200500122A (en) 2006-01-24
TW200613317A (en) 2006-05-01
PA8633601A1 (en) 2006-07-03
SV2006002123A (en) 2006-02-15
WO2005113575A1 (en) 2005-12-01
ZA200610769B (en) 2008-08-27
IL179293A0 (en) 2007-03-08
AR049547A1 (en) 2006-08-16
CR8785A (en) 2007-02-05
AU2005245568A1 (en) 2005-12-01
ECSP067028A (en) 2006-12-29
PE20060271A1 (en) 2006-05-25
EP1747229A1 (en) 2007-01-31
UY28911A1 (en) 2005-12-30
CN1993375A (en) 2007-07-04
NO20065885L (en) 2006-12-19
JP2007538026A (en) 2007-12-27
MXPA06013469A (en) 2007-01-23
EA200602049A1 (en) 2007-06-29
CA2564963A1 (en) 2005-12-01
DE102004025986A1 (en) 2005-12-15

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]