ECSP067028A - STEROID PROPHARMS WITH ANDROGENIC ACTION - Google Patents

STEROID PROPHARMS WITH ANDROGENIC ACTION

Info

Publication number
ECSP067028A
ECSP067028A EC2006007028A ECSP067028A ECSP067028A EC SP067028 A ECSP067028 A EC SP067028A EC 2006007028 A EC2006007028 A EC 2006007028A EC SP067028 A ECSP067028 A EC SP067028A EC SP067028 A ECSP067028 A EC SP067028A
Authority
EC
Ecuador
Prior art keywords
steroid
propharms
androgenic action
androgenic
action
Prior art date
Application number
EC2006007028A
Other languages
Spanish (es)
Inventor
Alexander Hillisch
Ralf Wyrwa
Sven Ring
Walter Elger
Birgitt Schneider
Peter Droescher
Gudrun Reddersen
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ECSP067028A publication Critical patent/ECSP067028A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

La presente invención se refiere a profármacos de esteroides con acción androgénica de la fórmula general (I), en los cuales el grupo Z está unido con el esteroide, a composiciones farmacéuticas que contienen estos compuestos, así como a su uso para la preparación de medicamentos con acción androgénica.The present invention relates to androgenic action steroid prodrugs of the general formula (I), in which the Z group is linked to the steroid, to pharmaceutical compositions containing these compounds, as well as to their use for the preparation of medicaments. with androgenic action.

EC2006007028A 2004-05-21 2006-11-27 STEROID PROPHARMS WITH ANDROGENIC ACTION ECSP067028A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004025986A DE102004025986A1 (en) 2004-05-21 2004-05-21 Steroid prodrugs with androgenic effects

Publications (1)

Publication Number Publication Date
ECSP067028A true ECSP067028A (en) 2006-12-29

Family

ID=34968657

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006007028A ECSP067028A (en) 2004-05-21 2006-11-27 STEROID PROPHARMS WITH ANDROGENIC ACTION

Country Status (22)

Country Link
EP (1) EP1747229A1 (en)
JP (1) JP2007538026A (en)
CN (1) CN1993375A (en)
AR (1) AR049547A1 (en)
AU (1) AU2005245568A1 (en)
BR (1) BRPI0510136A (en)
CA (1) CA2564963A1 (en)
CR (1) CR8785A (en)
DE (1) DE102004025986A1 (en)
EA (1) EA200602049A1 (en)
EC (1) ECSP067028A (en)
GT (1) GT200500122A (en)
IL (1) IL179293A0 (en)
MX (1) MXPA06013469A (en)
NO (1) NO20065885L (en)
PA (1) PA8633601A1 (en)
PE (1) PE20060271A1 (en)
SV (1) SV2006002123A (en)
TW (1) TW200613317A (en)
UY (1) UY28911A1 (en)
WO (1) WO2005113575A1 (en)
ZA (1) ZA200610769B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10027887A1 (en) 2000-05-31 2001-12-13 Jenapharm Gmbh Compounds with a sulfonamide group and pharmaceutical compositions containing these compounds
US7534780B2 (en) 2004-05-21 2009-05-19 Bayer Schering Pharma Aktiengesellschaft Estradiol prodrugs
DE102005057224A1 (en) * 2005-11-29 2007-05-31 Bayer Schering Pharma Ag New 9-alpha substituted estratriene derivatives esterified with a sulfamoylphenyl-substituted acid residue, are prodrugs useful as carboanhydrase inhibitors for treating estrogen deficiency disorders
DE102005057408A1 (en) * 2005-11-30 2007-05-31 Bayer Schering Pharma Ag New sulfamoylsulfonate prodrugs e.g. useful for protecting red blood cells from attack by parasites or for hormone replacement therapy, female fertility control or treating hormone-associated diseases
CN101708338B (en) * 2008-12-26 2014-06-04 中国人民解放军军事医学科学院放射与辐射医学研究所 Prodrug containing sterides structures and high dispersion preparation thereof
CN102964417A (en) * 2012-11-30 2013-03-13 华中药业股份有限公司 Synthetic method of 17-hydroxy tetrahydropyran ether steroid
CN107556258B (en) * 2017-08-22 2021-06-04 湖北江田精密化学有限公司 Preparation method of 4-amino-2-chloro-5 (1H-tetrazolyl-5) benzenesulfonamide
EP3533619A1 (en) * 2018-03-02 2019-09-04 Basf Se Heat sensitive recording material and color developer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH545316A (en) * 1970-07-17 1973-12-15 Hoffmann La Roche Process for the preparation of acyl derivatives
US5001234A (en) * 1987-04-16 1991-03-19 The Upjohn Company Cyclic hydrocarbons with an aminoalkyl sidechain
US5571933A (en) * 1994-11-17 1996-11-05 Duquesne University Of The Holy Ghost Derivatives of estra 1,3,5(10)triene-17-one, 3-amino compounds and their use
DE19712488A1 (en) * 1997-03-25 1998-10-01 Knoell Hans Forschung Ev Steroid sulfamates, processes for their preparation and use thereof
DE10027887A1 (en) * 2000-05-31 2001-12-13 Jenapharm Gmbh Compounds with a sulfonamide group and pharmaceutical compositions containing these compounds

Also Published As

Publication number Publication date
ZA200610769B (en) 2008-08-27
WO2005113575A1 (en) 2005-12-01
TW200613317A (en) 2006-05-01
AR049547A1 (en) 2006-08-16
UY28911A1 (en) 2005-12-30
MXPA06013469A (en) 2007-01-23
GT200500122A (en) 2006-01-24
EA200602049A1 (en) 2007-06-29
JP2007538026A (en) 2007-12-27
BRPI0510136A (en) 2007-10-02
IL179293A0 (en) 2007-03-08
SV2006002123A (en) 2006-02-15
EP1747229A1 (en) 2007-01-31
PE20060271A1 (en) 2006-05-25
AU2005245568A1 (en) 2005-12-01
CR8785A (en) 2007-02-05
CA2564963A1 (en) 2005-12-01
CN1993375A (en) 2007-07-04
DE102004025986A1 (en) 2005-12-15
PA8633601A1 (en) 2006-07-03
NO20065885L (en) 2006-12-19

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