BRPI0510487A - agentes de contraste para estudo por imagens de perfusão do miocárdio - Google Patents
agentes de contraste para estudo por imagens de perfusão do miocárdioInfo
- Publication number
- BRPI0510487A BRPI0510487A BRPI0510487-4A BRPI0510487A BRPI0510487A BR PI0510487 A BRPI0510487 A BR PI0510487A BR PI0510487 A BRPI0510487 A BR PI0510487A BR PI0510487 A BRPI0510487 A BR PI0510487A
- Authority
- BR
- Brazil
- Prior art keywords
- myocardial perfusion
- contrast agents
- imaging study
- perfusion imaging
- patient
- Prior art date
Links
- 239000002872 contrast media Substances 0.000 title abstract 3
- 238000003384 imaging method Methods 0.000 title abstract 3
- 230000002107 myocardial effect Effects 0.000 title abstract 3
- 230000010412 perfusion Effects 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000002059 diagnostic imaging Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/0412—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K51/0427—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/0412—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K51/0419—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/0412—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K51/0421—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
AGENTES DE CONTRASTE PARA ESTUDO POR IMAGENS DE PERFUSãO DO MIOCáRDIO. A presente invenção refere-se, em parte, a compostos e métodos para estudo por imagens de perfusão do miocárdio, compreendendo administrar a um paciente um agente de contraste o qual compreende um composto que liga MC-1, e uma porção para estudo por imagens, e triar o paciente usando diagnóstico por estudo por imagens.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56614604P | 2004-04-28 | 2004-04-28 | |
| US11/113,486 US7485283B2 (en) | 2004-04-28 | 2005-04-25 | Contrast agents for myocardial perfusion imaging |
| PCT/US2005/014459 WO2005105159A2 (en) | 2004-04-28 | 2005-04-27 | Contrast agents for myocardial perfusion imaging |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0510487A true BRPI0510487A (pt) | 2007-11-13 |
Family
ID=35187299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0510487-4A BRPI0510487A (pt) | 2004-04-28 | 2005-04-27 | agentes de contraste para estudo por imagens de perfusão do miocárdio |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US7485283B2 (pt) |
| EP (2) | EP1740225A4 (pt) |
| JP (1) | JP2007535547A (pt) |
| KR (1) | KR101207216B1 (pt) |
| CN (1) | CN101843908B (pt) |
| AU (1) | AU2005238080B2 (pt) |
| BR (1) | BRPI0510487A (pt) |
| CA (1) | CA2564737C (pt) |
| ES (1) | ES2744544T3 (pt) |
| IL (1) | IL178911A (pt) |
| MX (1) | MXPA06012299A (pt) |
| NO (1) | NO20065048L (pt) |
| RU (1) | RU2006141979A (pt) |
| SG (1) | SG152254A1 (pt) |
| WO (1) | WO2005105159A2 (pt) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| WO2004030659A1 (en) * | 2002-09-30 | 2004-04-15 | Acusphere, Inc. | Sustained release porous microparticles for inhalation |
| US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
| US6962006B2 (en) * | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
| JP2007533634A (ja) * | 2003-09-30 | 2007-11-22 | アキュスフィア, インコーポレイテッド | 注射、経口、または局所用の徐放性医薬製剤 |
| US7485283B2 (en) * | 2004-04-28 | 2009-02-03 | Lantheus Medical Imaging | Contrast agents for myocardial perfusion imaging |
| EP1888059B1 (en) | 2005-06-01 | 2014-12-17 | Edison Pharmaceuticals, Inc. | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| US7824659B2 (en) * | 2005-08-10 | 2010-11-02 | Lantheus Medical Imaging, Inc. | Methods of making radiolabeled tracers and precursors thereof |
| PL1933821T3 (pl) | 2005-09-15 | 2021-01-11 | Ptc Therapeutics, Inc. | Warianty łańcucha końcowego środków terapeutycznych o aktywności redoks do leczenia chorób mitochondrialnych i innych stanów oraz do modulacji biomarkerów energetycznych |
| US7913223B2 (en) * | 2005-12-16 | 2011-03-22 | Dialogic Corporation | Method and system for development and use of a user-interface for operations, administration, maintenance and provisioning of a telecommunications system |
| GB0525949D0 (en) | 2005-12-21 | 2006-02-01 | Hammersmith Imanet Ltd | Pet radiotracers |
| JP5374162B2 (ja) | 2006-02-22 | 2013-12-25 | エジソン ファーマシューティカルズ, インコーポレイテッド | ミトコンドリア病および他の症状の処置のためのレドックス活性化治療の側鎖変異体およびエネルギーバイオマーカーの調節 |
| WO2008133730A2 (en) * | 2006-11-15 | 2008-11-06 | The Regents Of The University Of California | Labeled rotenone analogs |
| WO2009110984A2 (en) * | 2008-02-29 | 2009-09-11 | Lantheus Medical Imaging, Inc. | Contrast agents for applications including perfusion imaging |
| WO2010004464A1 (en) * | 2008-07-09 | 2010-01-14 | Koninklijke Philips Electronics N.V. | Physiological pharmacokinetic analysis for combined molecular mri and dynamic pet imaging |
| LT3827815T (lt) | 2008-09-10 | 2023-10-10 | Ptc Therapeutics, Inc. | Psichologinių raidos sutrikimų gydymas oksidacijos redukcijos atžvilgiu aktyviais vaistais |
| EP2419096B1 (en) | 2009-04-15 | 2019-11-13 | Lantheus Medical Imaging, Inc. | Stabilization of radiopharmaceutical compositions using ascorbic acid |
| CN102858752B (zh) | 2010-02-08 | 2018-10-16 | 兰休斯医疗成像公司 | 用于合成显像剂和其中间体的方法和装置 |
| AU2012304359B2 (en) | 2011-09-09 | 2016-11-17 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| CN104771766A (zh) * | 2015-05-07 | 2015-07-15 | 张国明 | 心肌灌注成像的造影剂及制备方法 |
| JP6905527B2 (ja) | 2015-12-17 | 2021-07-21 | ピーティーシー セラピューティクス, インコーポレイテッド | 酸化ストレス障害を処置するためのフルオロアルキル、フルオロアルコキシ、フェノキシ、ヘテロアリールオキシ、アルコキシ、およびアミノ1,4−ベンゾキノン誘導体 |
| EP3203256A1 (en) * | 2016-02-02 | 2017-08-09 | B. Braun Melsungen AG | Calibration of mri systems using pre-defined concentrations of 19f isotopes as reference |
| CN106543117B (zh) * | 2016-11-10 | 2019-01-22 | 南京中医药大学 | 具有抗肿瘤活性的间双四氢呋喃型番荔枝内酯类化合物及其制备方法与应用 |
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| CN102858752B (zh) | 2010-02-08 | 2018-10-16 | 兰休斯医疗成像公司 | 用于合成显像剂和其中间体的方法和装置 |
-
2005
- 2005-04-25 US US11/113,486 patent/US7485283B2/en not_active Expired - Lifetime
- 2005-04-27 ES ES10176056T patent/ES2744544T3/es not_active Expired - Lifetime
- 2005-04-27 JP JP2007510933A patent/JP2007535547A/ja active Pending
- 2005-04-27 MX MXPA06012299A patent/MXPA06012299A/es not_active Application Discontinuation
- 2005-04-27 AU AU2005238080A patent/AU2005238080B2/en not_active Ceased
- 2005-04-27 CN CN201010193657.6A patent/CN101843908B/zh not_active Expired - Fee Related
- 2005-04-27 RU RU2006141979/04A patent/RU2006141979A/ru unknown
- 2005-04-27 EP EP05756378A patent/EP1740225A4/en not_active Withdrawn
- 2005-04-27 WO PCT/US2005/014459 patent/WO2005105159A2/en not_active Ceased
- 2005-04-27 EP EP10176056.9A patent/EP2253333B1/en not_active Expired - Lifetime
- 2005-04-27 SG SG200902714-5A patent/SG152254A1/en unknown
- 2005-04-27 CA CA2564737A patent/CA2564737C/en not_active Expired - Lifetime
- 2005-04-27 BR BRPI0510487-4A patent/BRPI0510487A/pt not_active Application Discontinuation
-
2006
- 2006-10-27 KR KR1020067022493A patent/KR101207216B1/ko not_active Expired - Fee Related
- 2006-10-29 IL IL178911A patent/IL178911A/en active IP Right Grant
- 2006-11-03 NO NO20065048A patent/NO20065048L/no not_active Application Discontinuation
-
2008
- 2008-12-19 US US12/339,694 patent/US8263042B2/en active Active
-
2012
- 2012-08-10 US US13/571,911 patent/US20130028837A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005105159A3 (en) | 2006-04-27 |
| EP1740225A4 (en) | 2009-08-19 |
| US20050244332A1 (en) | 2005-11-03 |
| MXPA06012299A (es) | 2006-12-15 |
| NO20065048L (no) | 2006-11-03 |
| IL178911A (en) | 2013-10-31 |
| EP1740225A2 (en) | 2007-01-10 |
| US20090104118A1 (en) | 2009-04-23 |
| ES2744544T3 (es) | 2020-02-25 |
| AU2005238080B2 (en) | 2011-02-10 |
| US7485283B2 (en) | 2009-02-03 |
| EP2253333B1 (en) | 2019-06-12 |
| AU2005238080A1 (en) | 2005-11-10 |
| US8263042B2 (en) | 2012-09-11 |
| RU2006141979A (ru) | 2008-06-10 |
| SG152254A1 (en) | 2009-05-29 |
| CA2564737A1 (en) | 2005-11-10 |
| WO2005105159A2 (en) | 2005-11-10 |
| JP2007535547A (ja) | 2007-12-06 |
| KR20070007859A (ko) | 2007-01-16 |
| CN101843908B (zh) | 2014-09-10 |
| US20130028837A1 (en) | 2013-01-31 |
| EP2253333A2 (en) | 2010-11-24 |
| IL178911A0 (en) | 2007-03-08 |
| CN101843908A (zh) | 2010-09-29 |
| CA2564737C (en) | 2014-03-18 |
| KR101207216B1 (ko) | 2012-12-03 |
| EP2253333A3 (en) | 2013-05-08 |
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