ATE439838T1 - Radiomarkierte neurokinin-1 rezeptor antagonisten - Google Patents
Radiomarkierte neurokinin-1 rezeptor antagonistenInfo
- Publication number
- ATE439838T1 ATE439838T1 AT99956491T AT99956491T ATE439838T1 AT E439838 T1 ATE439838 T1 AT E439838T1 AT 99956491 T AT99956491 T AT 99956491T AT 99956491 T AT99956491 T AT 99956491T AT E439838 T1 ATE439838 T1 AT E439838T1
- Authority
- AT
- Austria
- Prior art keywords
- neurokinin
- receptor antagonists
- radiom
- labeled
- mammals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Hydrogenated Pyridines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10233498P | 1998-09-29 | 1998-09-29 | |
| PCT/US1999/022163 WO2000018403A1 (en) | 1998-09-29 | 1999-09-24 | Radiolabeled neurokinin-1 receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE439838T1 true ATE439838T1 (de) | 2009-09-15 |
Family
ID=22289321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99956491T ATE439838T1 (de) | 1998-09-29 | 1999-09-24 | Radiomarkierte neurokinin-1 rezeptor antagonisten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6241964B1 (de) |
| EP (1) | EP1119356B1 (de) |
| JP (1) | JP2002525325A (de) |
| AT (1) | ATE439838T1 (de) |
| AU (1) | AU1309100A (de) |
| CA (1) | CA2343106A1 (de) |
| DE (1) | DE69941298D1 (de) |
| WO (1) | WO2000018403A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7344702B2 (en) * | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| US20040171836A1 (en) * | 2001-12-21 | 2004-09-02 | Toshihiro Fujino | Method for producing optical-active cis-piperidine derivatives |
| ATE487479T1 (de) * | 2002-09-24 | 2010-11-15 | Merck Sharp & Dohme | Radioaktiv markierte neurokinin-1-rezeptor- antagonisten |
| CA2538520C (en) | 2003-07-24 | 2015-02-10 | The Queen's Medical Center | Preparation and use of alkylating agents |
| CA2531573C (en) * | 2003-08-01 | 2010-04-13 | Toyo Kasei Kogyo Company Limited | Alkoxy-(tetrazol-1-yl)benzaldehyde compound and process for producing the same |
| US7485283B2 (en) * | 2004-04-28 | 2009-02-03 | Lantheus Medical Imaging | Contrast agents for myocardial perfusion imaging |
| KR100808547B1 (ko) | 2005-06-22 | 2008-02-29 | 재단법인서울대학교산학협력재단 | 펩타이드 수용체 영상용 제제로 사용할 수 있는 ｆ－１８－플로로벤질리덴하이드라존－니코틴아마이드－펩타이드 유도체 및 펩타이드에 방사성불소를 효율적으로 표지하기 위한 방법 |
| US7824659B2 (en) | 2005-08-10 | 2010-11-02 | Lantheus Medical Imaging, Inc. | Methods of making radiolabeled tracers and precursors thereof |
| EP1942733B1 (de) * | 2005-09-29 | 2012-03-21 | Merck Sharp & Dohme Corp. | Radioaktiv markierte glycintransporter-hemmer |
| US8506928B2 (en) * | 2007-09-07 | 2013-08-13 | The Regents Of The University Of California | Methods and compounds for targeting tissues |
| KR101616139B1 (ko) | 2008-02-29 | 2016-04-27 | 랜티우스 메디컬 이메징, 인크. | 관류 영상화를 포함하는 용도를 위한 조영제 |
| US20110318266A1 (en) * | 2008-09-16 | 2011-12-29 | Mccauley John A | Phthalimide derivative metabotropic glutamate r4 ligands |
| USRE49686E1 (en) | 2008-09-19 | 2023-10-10 | Takeda Pharmaceutical Company Limited | Nitrogen-containing heterocyclic compound and use of same |
| CN102458396B (zh) | 2009-04-15 | 2017-05-10 | 兰休斯医疗成像公司 | 使用抗坏血酸稳定化放射性药物组合物 |
| AU2011213568B2 (en) | 2010-02-08 | 2016-05-12 | Lantheus Medical Imaging, Inc. | Methods and apparatus for synthesizing imaging agents, and intermediates thereof |
| AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| EP2774930A1 (de) | 2013-03-07 | 2014-09-10 | Aptenia S.R.L. | Metallocenverbindungen und markierte Moleküle damit für In-vivo-Bildgebung |
| CN120441539A (zh) | 2024-02-08 | 2025-08-08 | 上海数因信科智能科技有限公司 | 四唑类化合物、其药物组合物及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2229259T3 (es) * | 1995-01-12 | 2005-04-16 | Glaxo Group Limited | Derivados de piperidina con actividad antagonista de taquiquinina. |
| GB9505692D0 (en) * | 1995-03-21 | 1995-05-10 | Glaxo Group Ltd | Chemical compounds |
| JPH08325169A (ja) * | 1995-03-29 | 1996-12-10 | Nkk Corp | フッ素放射性同位元素標識有機化合物の製造方法 |
| US5719156A (en) * | 1995-05-02 | 1998-02-17 | Schering Corporation | Piperazino derivatives as neurokinin antagonists |
| FI104048B (fi) | 1997-06-16 | 1999-11-15 | Map Medical Technologies Oy | Prosessi tuottaa radiojodattuja reseptoriaineita in vivo käyttöön |
-
1999
- 1999-09-24 AT AT99956491T patent/ATE439838T1/de not_active IP Right Cessation
- 1999-09-24 DE DE69941298T patent/DE69941298D1/de not_active Expired - Lifetime
- 1999-09-24 JP JP2000571921A patent/JP2002525325A/ja not_active Withdrawn
- 1999-09-24 CA CA002343106A patent/CA2343106A1/en not_active Abandoned
- 1999-09-24 EP EP99956491A patent/EP1119356B1/de not_active Expired - Lifetime
- 1999-09-24 WO PCT/US1999/022163 patent/WO2000018403A1/en not_active Ceased
- 1999-09-24 AU AU13091/00A patent/AU1309100A/en not_active Abandoned
- 1999-09-28 US US09/407,822 patent/US6241964B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2343106A1 (en) | 2000-04-06 |
| EP1119356A4 (de) | 2008-01-09 |
| EP1119356A1 (de) | 2001-08-01 |
| JP2002525325A (ja) | 2002-08-13 |
| EP1119356B1 (de) | 2009-08-19 |
| AU1309100A (en) | 2000-04-17 |
| DE69941298D1 (de) | 2009-10-01 |
| US6241964B1 (en) | 2001-06-05 |
| WO2000018403A1 (en) | 2000-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |