BRPI0510512A - derivados de arilfenilamino, arilfenilamida e sulfeto de arilfeniléter - Google Patents

derivados de arilfenilamino, arilfenilamida e sulfeto de arilfeniléter

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Publication number
BRPI0510512A
BRPI0510512A BRPI0510512-9A BRPI0510512A BRPI0510512A BR PI0510512 A BRPI0510512 A BR PI0510512A BR PI0510512 A BRPI0510512 A BR PI0510512A BR PI0510512 A BRPI0510512 A BR PI0510512A
Authority
BR
Brazil
Prior art keywords
arylphenylamino
arylphenylamide
sulfide derivatives
compounds
arylphenyl ether
Prior art date
Application number
BRPI0510512-9A
Other languages
English (en)
Inventor
Donovan Chin
Thomas Durand-Reville
Francine S Farouz
Kerry W Fowler
Kevin Guckian
Irina Jacobson
Ramesk Kasar
Russell C Peter
Daniel Scott
Gregory C Sowell
Eugene Thorsett
Edward Yin-Shiang Lin
Original Assignee
Icos Corp
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp, Biogen Idec Inc filed Critical Icos Corp
Publication of BRPI0510512A publication Critical patent/BRPI0510512A/pt

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    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

DERIVADOS DE ARILFENILAMINO, ARILFENILAMIDA E SULFETO DE ARILFENILéTER. A presente invenção relaciona-se em parte a compostos de fórmulas I e III: e sais e pró-medicamentos farmacêuticamente aceitáveis desses. Esses compostos podem ser úteis para o tratamento de doenças como doenças inflamatórias e imunes. A presente invenção também se relaciona a composições farmacêuticas que compreendem esses compostos e a métodos de inibição da inflamação ou supressão da resposta imune em um indivíduo.
BRPI0510512-9A 2004-04-28 2005-04-28 derivados de arilfenilamino, arilfenilamida e sulfeto de arilfeniléter BRPI0510512A (pt)

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US56582604P 2004-04-28 2004-04-28
US62031604P 2004-10-20 2004-10-20
PCT/US2005/014778 WO2005105770A2 (en) 2004-04-28 2005-04-28 Arylphenylamino-, arylphenylamide-, and arylphenylether-sulfide derivatives

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US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
MX2012003604A (es) 2009-09-27 2012-09-12 Opx Biotechnologies Inc Metodo para producir acido 3-hidroxipropionico y otros productos.
MX2015001780A (es) 2012-08-10 2015-09-28 Opx Biotechnologies Inc Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos.
US20150119601A1 (en) 2013-03-15 2015-04-30 Opx Biotechnologies, Inc. Monofunctional mcr + 3-hp dehydrogenase
EP2976141A4 (en) 2013-03-15 2016-10-05 Cargill Inc FLASHING FOR PRODUCTION CLEANING AND RECOVERY
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
EP3022310B1 (en) 2013-07-19 2019-10-16 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
WO2016116875A1 (en) 2015-01-20 2016-07-28 Novartis Ag Pet imaging agents
US11345938B2 (en) 2017-02-02 2022-05-31 Cargill, Incorporated Genetically modified cells that produce C6-C10 fatty acid derivatives

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US6521619B2 (en) * 2000-06-29 2003-02-18 Icos Corporation Aryl phenylcyclopropyl sulfide derivatives and their use as cell adhesion inhibiting anti-inflammatory and immune suppressive agents
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WO2005105770A3 (en) 2006-03-09
US20070259863A1 (en) 2007-11-08
MXPA06012486A (es) 2007-03-15
RU2006141832A (ru) 2008-06-10
JP2007535554A (ja) 2007-12-06
CA2562176A1 (en) 2005-11-10
AU2005238534A1 (en) 2005-11-10
WO2005105770A2 (en) 2005-11-10
IL178888A0 (en) 2007-03-08
NO20065256L (no) 2006-11-15
EP1740565A2 (en) 2007-01-10

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