BRPI0510645A - diagnóstico ou prognóstico do progresso do cáncer de mama, composição compreendendo conjuntos de iniciador/sonda de ácido nucléico e kit para análise de linfonodo intraoperativo - Google Patents

diagnóstico ou prognóstico do progresso do cáncer de mama, composição compreendendo conjuntos de iniciador/sonda de ácido nucléico e kit para análise de linfonodo intraoperativo

Info

Publication number
BRPI0510645A
BRPI0510645A BRPI0510645-1A BRPI0510645A BRPI0510645A BR PI0510645 A BRPI0510645 A BR PI0510645A BR PI0510645 A BRPI0510645 A BR PI0510645A BR PI0510645 A BRPI0510645 A BR PI0510645A
Authority
BR
Brazil
Prior art keywords
breast cancer
prognosis
diagnosis
nucleic acid
composition
Prior art date
Application number
BRPI0510645-1A
Other languages
English (en)
Inventor
David Atkins
John Backus
Robert Belly
Steve Rosen
Robert White
Original Assignee
Veridex Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Veridex Llc filed Critical Veridex Llc
Publication of BRPI0510645A publication Critical patent/BRPI0510645A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

DIAGNóSTICO OU PROGNóSTICO DO PROGRESSO DO CáNCER DE MAMA, COMPOSIçãO COMPREENDENDO CONJUNTOS DE INICIADOR/SONDA DE áCIDO NUCLéICO E KIT PARA ANáLISE DE LINFONODO INTRAOPERATIVO. Um método de diagnosticar a presença ou predizer o progresso de câncer de mama pela medida da expressão de uma combinação de genes Marcadores compreendendo um gene específico de tecido e um gene específico de não tecido em uma célula ou amostra de tecido derivada de um paciente. Em um aspecto da invenção, os genes são mamaglobina e CK 19. São fornecidos kits, iniciadores e sondas e controles.
BRPI0510645-1A 2004-06-04 2005-06-06 diagnóstico ou prognóstico do progresso do cáncer de mama, composição compreendendo conjuntos de iniciador/sonda de ácido nucléico e kit para análise de linfonodo intraoperativo BRPI0510645A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57715504P 2004-06-04 2004-06-04
PCT/US2005/019616 WO2005118875A2 (en) 2004-06-04 2005-06-06 Diagnosing or predicting the course of breast cancer

Publications (1)

Publication Number Publication Date
BRPI0510645A true BRPI0510645A (pt) 2007-11-20

Family

ID=35463474

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510645-1A BRPI0510645A (pt) 2004-06-04 2005-06-06 diagnóstico ou prognóstico do progresso do cáncer de mama, composição compreendendo conjuntos de iniciador/sonda de ácido nucléico e kit para análise de linfonodo intraoperativo

Country Status (11)

Country Link
US (1) US20090298052A1 (pt)
EP (1) EP1766079A4 (pt)
JP (1) JP2008502330A (pt)
CN (1) CN101432437A (pt)
AU (2) AU2005250479B2 (pt)
BR (1) BRPI0510645A (pt)
CA (1) CA2569502A1 (pt)
IL (1) IL179715A0 (pt)
MX (1) MXPA06014175A (pt)
NZ (1) NZ551430A (pt)
WO (1) WO2005118875A2 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100405065C (zh) * 2005-12-27 2008-07-23 厦门大学附属中山医院 纳米胶体金膀胱癌免疫层析检测试剂条及其检测方法
JP4968577B2 (ja) * 2006-04-11 2012-07-04 エフ．ホフマン−ラ ロシュ アーゲー サイトケラチン１９（ＣＫ１９）ｍＲＮＡの迅速測定法、並びにそのためのプライマー及びプローブ
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
JP2009537154A (ja) 2006-05-18 2009-10-29 モレキュラー プロファイリング インスティテュート， インコーポレイテッド 疾患状態に対する個別化された医学的介入を決定するためのシステムおよび方法
US8043815B2 (en) 2007-08-06 2011-10-25 Health Research, Inc. Methods for analysis of PDEF and survivin as interconnected cancer biomarkers and targets for personalized medicine
CA2743211A1 (en) 2008-11-12 2010-05-20 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Methods and systems of using exosomes for determining phenotypes
GB0908589D0 (en) * 2009-05-19 2009-06-24 Univ Belfast Assay method
EP2542696B1 (en) 2010-03-01 2016-09-28 Caris Life Sciences Switzerland Holdings GmbH Biomarkers for theranostics
BR112012025593A2 (pt) 2010-04-06 2019-06-25 Caris Life Sciences Luxembourg Holdings biomarcadores em circulação para doença
US10011876B2 (en) 2010-11-23 2018-07-03 Krisani Biosciences Pvt. Ltd Method and system for prognosis and treatment of diseases using portfolio of genes
US20130217071A1 (en) * 2011-12-30 2013-08-22 Luz Montesclaros Methods and compositions for performing nucleic acid amplification reactions
CN106755459A (zh) * 2017-01-09 2017-05-31 浙江大学 一种用于检测乳腺癌的引物组及检测方法
CN113462761B (zh) * 2021-07-30 2024-02-09 宁波胤瑞生物医学仪器有限责任公司 一种检测her2基因的引物探针组合物及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4715545A (en) * 1986-02-13 1987-12-29 Sage Products, Inc. Tissue grinding and transport system and method
GB8920097D0 (en) * 1989-09-06 1989-10-18 Ici Plc Amplification processes
ES2141088T3 (es) * 1990-02-16 2000-03-16 Hoffmann La Roche Mejoras en la especificidad y conveniencia de la reaccion en cadena de la polimerasa.
US5413924A (en) * 1992-02-13 1995-05-09 Kosak; Kenneth M. Preparation of wax beads containing a reagent for release by heating
CA2168712A1 (en) * 1995-02-07 1996-08-08 John William Henderson Sutherland Use of exonuclease and/or glycosylase as supplements to anti-polymerase antibody to increase specificity in polymerase chain reaction
US6037129A (en) * 1998-05-28 2000-03-14 Medical University Of South Carolina Multi-marker RT-PCR panel for detecting metastatic breast cancer
GB9812768D0 (en) * 1998-06-13 1998-08-12 Zeneca Ltd Methods
EP1272668B1 (en) * 2000-04-03 2007-02-14 Corixa Corporation Methods, compositions and kits for the detection and monitoring of breast cancer
US6403341B1 (en) * 2001-08-02 2002-06-11 Wayne M. Barnes Magnesium precipitate hot start method for PCR
US7267950B2 (en) * 2003-05-01 2007-09-11 Veridex, Lcc Rapid extraction of RNA from cells and tissues

Also Published As

Publication number Publication date
WO2005118875A2 (en) 2005-12-15
NZ551430A (en) 2010-01-29
IL179715A0 (en) 2007-05-15
AU2009243522A1 (en) 2009-12-24
EP1766079A4 (en) 2010-06-23
WO2005118875A3 (en) 2009-06-04
CN101432437A (zh) 2009-05-13
AU2005250479A1 (en) 2005-12-15
CA2569502A1 (en) 2005-12-15
US20090298052A1 (en) 2009-12-03
JP2008502330A (ja) 2008-01-31
AU2005250479B2 (en) 2010-07-22
MXPA06014175A (es) 2007-05-09
EP1766079A2 (en) 2007-03-28

Similar Documents

Publication Publication Date Title
CN106661619B (zh) 大肠癌的检测试剂盒或装置以及检测方法
ES2605237T3 (es) Novedosos marcadores para la detección del cáncer de vejiga
Ma et al. Characterization of microRNA transcriptome in lung cancer by next-generation deep sequencing
US9249465B2 (en) Molecular markers for lung and colorectal carcinomas
BRPI0510645A (pt) diagnóstico ou prognóstico do progresso do cáncer de mama, composição compreendendo conjuntos de iniciador/sonda de ácido nucléico e kit para análise de linfonodo intraoperativo
KR101987358B1 (ko) 신규한 간암 진단용 바이오 마커 및 이의 용도
miRNA Concentration Circulating miRNA signatures: promising prognostic tools for cancer
WO2005044990A3 (en) Use of differentially expressed nucleic acid sequences as biomarkers for cancer
HU0400904D0 (en) Use of genes as molecular markers in diagnosis of schizophrenia and diagnostic kit for the same
ES2965535T3 (es) Métodos de diagnóstico y tratamiento de pacientes con carcinoma cutáneo de células epidermoides
Odenthal et al. Serum micro RNA profiles as prognostic/predictive markers in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction
CN106662543A (zh) 肺癌患者中的非侵入性基因突变检测
Langevin et al. Novel DNA methylation targets in oral rinse samples predict survival of patients with oral squamous cell carcinoma
Lissa et al. HOXA9 methylation and blood vessel invasion in FFPE tissues for prognostic stratification of stage I lung adenocarcinoma patients
Vaclavikova et al. Development of high-resolution melting analysis for ABCB1 promoter methylation: Clinical consequences in breast and ovarian carcinoma
Chiam et al. Identification of microRNA Biomarkers of Response to Neoadjuvant Chemoradiotherapy in Esophageal Adenocarcinoma Using Next Generation Sequencing: K. Chiam et al.
KR20160022017A (ko) 재발 난소암 진단 또는 난소암 재발 예측용 mirna 마커 및 그 용도
JP2005530518A5 (pt)
ATE429495T1 (de) Nukleinsäuren für die apoptose von krebszellen
CN110023510A (zh) 作为卵巢癌预后诊断标志物的mmp1基因转录产物和检测方法
KR102844902B1 (ko) 간암 발병의 위험성 예측용 조성물
JP2023537870A (ja) 肺がんを診断及び監視するためのバイオマーカー
ES2946681T3 (es) Genes y firmas génicas para el diagnóstico y tratamiento del melanoma
Wen et al. Breast cancer pathology in the era of genomics
ASHooRi et al. Evaluation of the Epigenetic Biomarker Bone Morphogenic Protein 3 for Colorectal Cancer Diagnosis.

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2204 DE 02/04/2013.