BRPI0510694A - composições farmacêuticas compreendendo ingredientes ativos concentrados encapsuladas em gelatina mole - Google Patents

composições farmacêuticas compreendendo ingredientes ativos concentrados encapsuladas em gelatina mole

Info

Publication number
BRPI0510694A
BRPI0510694A BRPI0510694-0A BRPI0510694A BRPI0510694A BR PI0510694 A BRPI0510694 A BR PI0510694A BR PI0510694 A BRPI0510694 A BR PI0510694A BR PI0510694 A BRPI0510694 A BR PI0510694A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
active ingredients
soft gelatin
encapsulated active
concentrated
Prior art date
Application number
BRPI0510694-0A
Other languages
English (en)
Inventor
Jayant Ekanth Khanolkar
Shane Michael De La Harpe
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of BRPI0510694A publication Critical patent/BRPI0510694A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

COMPOSIçõES FARMACêUTICAS COMPREENDENDO INGREDIENTES ATIVOS CONCENTRADOS ENCAPSULADAS EM GELATINA MOLE. A presente invenção refere-se a composições farmacêuticas que compreendem um ativo farmacêutico altamente concentrado e um agente estabilizante em suspensão em um solvente. Essas composições farmacêuticas são adequadas à encapsulação no interior de cápsulas de gelatina mole tendo estabilidade otimizada.
BRPI0510694-0A 2004-05-06 2005-05-05 composições farmacêuticas compreendendo ingredientes ativos concentrados encapsuladas em gelatina mole BRPI0510694A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/840,143 US20050249802A1 (en) 2004-05-06 2004-05-06 Softgel encapsulated pharmaceutical compositions comprising concentrated active ingredients
PCT/US2005/015746 WO2005107709A2 (en) 2004-05-06 2005-05-05 Softgel encapsulated pharmaceutical compositions comprising concentrated active ingredients

Publications (1)

Publication Number Publication Date
BRPI0510694A true BRPI0510694A (pt) 2007-12-26

Family

ID=35239693

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510694-0A BRPI0510694A (pt) 2004-05-06 2005-05-05 composições farmacêuticas compreendendo ingredientes ativos concentrados encapsuladas em gelatina mole

Country Status (11)

Country Link
US (1) US20050249802A1 (pt)
EP (1) EP1744733B1 (pt)
JP (1) JP2007536257A (pt)
CN (1) CN1980646B (pt)
AU (1) AU2005240187B2 (pt)
BR (1) BRPI0510694A (pt)
CA (1) CA2565252C (pt)
ES (1) ES2699711T3 (pt)
MX (1) MXPA06012738A (pt)
PL (1) PL1744733T3 (pt)
WO (1) WO2005107709A2 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0526419D0 (en) * 2005-12-23 2006-02-08 Cyclacel Ltd Formulation
KR20090088913A (ko) 2006-11-21 2009-08-20 맥네일-피피씨, 인코포레이티드 개질된 방출형 진통 현탁제
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
JP5503939B2 (ja) * 2009-10-16 2014-05-28 東洋カプセル株式会社 アゼラスチン塩酸塩含有カプセル剤
PL3515413T3 (pl) 2016-09-26 2023-11-13 The Procter & Gamble Company Postać dawkowania zapewniająca przedłużoną ulgę
CA3100314A1 (en) 2018-05-16 2019-11-21 Bayer Healthcare Llc High concentration suspension formulation for cold and flu soft gel capsule medications
EP3952900A1 (en) 2019-04-11 2022-02-16 R.P. Scherer Technologies, LLC Formulation for oral delivery of proteins, peptides and small molecules with poor permeability
CN113398274B (zh) * 2021-06-11 2022-05-31 包头东宝生物技术股份有限公司 提升明胶溶解性能的方法和该方法制备的高溶解性明胶

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002777A (en) * 1986-06-24 1991-03-26 Norcliff Thayer Inc. Encapsulated antacid
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
US5141961A (en) * 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives
US5484606A (en) * 1994-01-24 1996-01-16 The Procter & Gamble Company Process for reducing the precipitation of difficulty soluble pharmaceutical actives
NZ280610A (en) * 1994-12-29 1997-08-22 Mcneil Ppc Inc Soft gelatin-like pharmaceutical carrier: gelled polyethylene glycol and dispersed active agent
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
US5569466A (en) * 1995-05-17 1996-10-29 R. P. Scherer Corporation Fill compositions for soft elastic gel capsules
CA2223768A1 (en) * 1995-06-09 1996-12-27 R.P. Scherer Corporation Suspension and soft gelatin capsules containing particulate matter
US5919481A (en) * 1996-06-28 1999-07-06 Ncneil-Ppc, Inc. Fill material for soft gelatin pharmaceutical dosage form
US5908636A (en) * 1996-06-28 1999-06-01 Mcneil-Ppc, Inc. Fill material for soft gelatin pharmaceutical dosage form containing an antiflatulent
US6024980A (en) * 1996-06-28 2000-02-15 Mcneil-Ppc, Inc. Multiphase soft gelatin dosage form
EP0946145B1 (en) * 1996-12-20 2008-09-03 McNeil-PPC, Inc. Antitussive drugs delivered by ion exchange resins
US6197787B1 (en) * 1997-03-03 2001-03-06 Sanofi-Synthelabo Pharmaceutical formulations containing poorly soluble drug substances
US6383515B2 (en) * 1999-05-28 2002-05-07 Sawyer Maryjean Solvent system for enhancing solubility
US6251426B1 (en) * 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
CZ2002947A3 (cs) * 1999-09-29 2002-08-14 The Procter & Gamble Company Kapalný prostředek, nejlépe orální prostředek se zlepąenou stabilitou a způsob přípravy
US6387400B1 (en) * 2000-08-29 2002-05-14 R.P. Scherer Technologies, Inc. Process for preparing pharmaceutical compositions for use with soft gelatin formulations
US7138133B2 (en) * 2001-10-10 2006-11-21 The Procter & Gamble Company Orally administered liquid compositions

Also Published As

Publication number Publication date
AU2005240187A1 (en) 2005-11-17
CA2565252A1 (en) 2005-11-17
ES2699711T3 (es) 2019-02-12
WO2005107709A2 (en) 2005-11-17
CN1980646B (zh) 2010-05-26
CN1980646A (zh) 2007-06-13
US20050249802A1 (en) 2005-11-10
AU2005240187B2 (en) 2009-07-02
WO2005107709A3 (en) 2006-12-07
EP1744733B1 (en) 2018-09-19
CA2565252C (en) 2010-04-13
JP2007536257A (ja) 2007-12-13
MXPA06012738A (es) 2007-01-16
PL1744733T3 (pl) 2019-02-28
EP1744733A2 (en) 2007-01-24

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]