BRPI0510761A - métodos de tratar um paciente afligido com pelo menos uma enfermidade e de reduzir ou eliminar rugas - Google Patents
métodos de tratar um paciente afligido com pelo menos uma enfermidade e de reduzir ou eliminar rugasInfo
- Publication number
- BRPI0510761A BRPI0510761A BRPI0510761-0A BRPI0510761A BRPI0510761A BR PI0510761 A BRPI0510761 A BR PI0510761A BR PI0510761 A BRPI0510761 A BR PI0510761A BR PI0510761 A BRPI0510761 A BR PI0510761A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- treating
- reducing
- effective amount
- patient afflicted
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000037303 wrinkles Effects 0.000 title abstract 2
- 230000005540 biological transmission Effects 0.000 abstract 2
- 230000002452 interceptive effect Effects 0.000 abstract 2
- 230000001537 neural effect Effects 0.000 abstract 2
- 206010002091 Anaesthesia Diseases 0.000 abstract 1
- 206010021118 Hypotonia Diseases 0.000 abstract 1
- 208000007101 Muscle Cramp Diseases 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 230000037005 anaesthesia Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000036640 muscle relaxation Effects 0.000 abstract 1
- 230000000474 nursing effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
MéTODOS DE TRATAR UM PACIENTE AFLIGIDO COM PELO MENOS UMA ENFERMIDADE E DE REDUZIR OU ELIMINAR RUGAS Composições farmacêuticas para interferir com a transmissão neuronal que compreende uma quantidade eficaz de pelo menos uma 3,4-propinoperidropurina tricíclica e pelo menos um composto adicional são divulgadas. Preparações para aplicações tópicas são fornecidas que compreendem uma quantidade eficaz da composição da invenção e um veiculo farmacologicamente aceitável. Métodos de interferir com a transmissão neuronal que compreende a aplicação tópica de uma quantidade eficaz da pelo menos uma 3,4-propinoperidropurina tricíclica são fornecidos para o tratamento de urna variedade de indicações que dizem respeito ao relaxamento muscular, anestesia, espasmos musculares e causas similares.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56938304P | 2004-05-07 | 2004-05-07 | |
| US56938004P | 2004-05-07 | 2004-05-07 | |
| PCT/US2005/015946 WO2005110417A1 (en) | 2004-05-07 | 2005-05-06 | Phycotoxins and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0510761A true BRPI0510761A (pt) | 2007-11-20 |
Family
ID=35393960
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0510759-8A BRPI0510759A (pt) | 2004-05-07 | 2005-05-06 | método de facilitar a cura de um ferimento |
| BRPI0510761-0A BRPI0510761A (pt) | 2004-05-07 | 2005-05-06 | métodos de tratar um paciente afligido com pelo menos uma enfermidade e de reduzir ou eliminar rugas |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0510759-8A BRPI0510759A (pt) | 2004-05-07 | 2005-05-06 | método de facilitar a cura de um ferimento |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20070280970A1 (pt) |
| EP (2) | EP1802250A4 (pt) |
| JP (2) | JP2007536269A (pt) |
| CN (1) | CN1997373B (pt) |
| AU (2) | AU2005244105B2 (pt) |
| BR (2) | BRPI0510759A (pt) |
| CA (3) | CA2606530C (pt) |
| ES (1) | ES2646087T3 (pt) |
| MX (2) | MXPA06012961A (pt) |
| WO (2) | WO2005110417A1 (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050220821A1 (en) * | 2004-03-31 | 2005-10-06 | Allergan, Inc. | Pressure sore treatment |
| JP2007538010A (ja) * | 2004-05-07 | 2007-12-27 | ファイトトックス リミテッド | フィコトキシンの経皮投与 |
| JP2007536269A (ja) * | 2004-05-07 | 2007-12-13 | ファイトトックス リミテッド | ゴニオトキシンを用いた創傷の治療方法 |
| WO2006119499A2 (en) * | 2005-05-05 | 2006-11-09 | Phytotox Limited | Use of phycotoxins in veterinary applications |
| US9012477B2 (en) * | 2009-01-06 | 2015-04-21 | Nuvo Research Inc. | Method of treating neuropathic pain |
| US20100184685A1 (en) * | 2009-01-19 | 2010-07-22 | Zavala Jr Gerardo | Systems and methods for treating post- operative, acute, and chronic pain using an intra-muscular catheter administrated combination of a local anesthetic and a neurotoxin protein |
| CL2009000723A1 (es) * | 2009-03-24 | 2009-06-19 | Proteus Sa | Metodo de purificacion industrial de ficotoxinas biologicamente activas que comprende proporcionar una cantidad adecuada de una fuente de ficotoxinas como por ejemplo el cultivo de un clon de cianobacterias. |
| CA2757302A1 (en) * | 2009-04-01 | 2010-10-07 | Andrew Crockett | Methods for treating myofascial, muscle, and/or back pain |
| US9186334B2 (en) | 2009-05-04 | 2015-11-17 | Nuvo Research Inc. | Heat assisted lidocaine and tetracaine for transdermal analgesia |
| WO2010129542A1 (en) * | 2009-05-04 | 2010-11-11 | Jie Zhang | Methods of treating pains associated with neuroma, nerve entrapment, and other conditions |
| CA2760946C (en) * | 2009-05-07 | 2019-06-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for studying, imaging, and treating pain |
| US9693976B2 (en) | 2010-01-14 | 2017-07-04 | Crescita Therapeutics Inc. | Solid-forming local anesthetic formulations for pain control |
| JP6112867B2 (ja) * | 2010-02-10 | 2017-04-12 | ファイトトックス リミテッドPhytotox Limited | サキシトキシン誘導体での触覚の喪失の処置 |
| US20130251783A1 (en) * | 2011-09-14 | 2013-09-26 | Universitat Heidelberg | Liposomes containing permeation enhancers for oral drug delivery |
| EP2638908A1 (en) * | 2012-03-16 | 2013-09-18 | Phytotox SpA | Paralytic Shellfish Poison |
| WO2015157559A2 (en) | 2014-04-09 | 2015-10-15 | Siteone Therapeutics, Inc. | 10',11'-modified saxitoxins for the treatment of pain |
| US20170049701A1 (en) * | 2015-08-05 | 2017-02-23 | Steven M. Kushner | Clustoidal multilamellar soy lecithin phospholipid structures for transdermal, transmucosal, or oral delivery, improved intestinal absorption, and improved bioavailability of nutrients |
| ES2895155T3 (es) | 2015-09-30 | 2022-02-17 | Siteone Therapeutics Inc | Saxitoxinas modificadas en 11,13 para el tratamiento del dolor |
| US11279706B2 (en) | 2017-03-29 | 2022-03-22 | Siteone Therapeutics, Inc. | 11,13-modified saxitoxins for the treatment of pain |
| CN110831945B (zh) | 2017-03-29 | 2023-08-08 | 赛特温治疗公司 | 用于治疗疼痛的11,13-修饰的石房蛤毒素类化合物 |
| EP3860714B1 (en) | 2018-10-03 | 2023-09-06 | Siteone Therapeutics, Inc. | 11,13-modified saxitoxins for the treatment of pain |
| WO2022112887A1 (en) * | 2020-11-25 | 2022-06-02 | Algenis | Method of treating acute nociceptive pain in mammals |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3652762A (en) | 1970-04-14 | 1972-03-28 | Ciba Geigy Corp | Pharmaceutical compositions and methods employing substituted derivatives of 2-anilinophenylacetic acids and esters |
| US3957966A (en) * | 1972-05-19 | 1976-05-18 | Gaf Corporation | Stabilized vitamin food coatings |
| US4022899A (en) * | 1973-06-12 | 1977-05-10 | Astra Pharmaceutical Products, Inc. | Synergistic local anesthetic compositions |
| US4029794A (en) * | 1973-06-12 | 1977-06-14 | Astra Pharmaceutical Products, Inc. | Pharmaceutical local anesthetic composition |
| US4001413A (en) * | 1973-06-12 | 1977-01-04 | Astra Pharmaceutical Products, Inc. | Pharmaceutical local anesthetic composition employing saxitoxin |
| US4537776A (en) * | 1983-06-21 | 1985-08-27 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone |
| US5183462A (en) * | 1990-08-21 | 1993-02-02 | Associated Synapse Biologics | Controlled administration of chemodenervating pharmaceuticals |
| GB9120306D0 (en) * | 1991-09-24 | 1991-11-06 | Graham Herbert K | Method and compositions for the treatment of cerebral palsy |
| US5562907A (en) * | 1993-05-14 | 1996-10-08 | Arnon; Stephen S. | Method to prevent side-effects and insensitivity to the therapeutic uses of toxins |
| US5437291A (en) * | 1993-08-26 | 1995-08-01 | Univ Johns Hopkins | Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction |
| EP0758900B1 (en) * | 1994-05-09 | 2002-04-10 | BINDER, William J. | Botulinum toxin FOR REDUCTION OF migraine HEADACHE PAIN |
| US5504117A (en) * | 1994-05-27 | 1996-04-02 | Neptune Pharmaceutical Corporation | Pharmacologic preparation for the treatment of anal disorders |
| JP3517031B2 (ja) * | 1995-06-09 | 2004-04-05 | 日清紡績株式会社 | 生物学的活性物質の分析法 |
| US5837265A (en) * | 1996-03-08 | 1998-11-17 | The Regents Of The University Of California | Chemically-modified clostridiatoxin with improved properties |
| US5721215A (en) * | 1996-03-20 | 1998-02-24 | Allergan | Injectable therapy for control of muscle spasms and pain related to muscle spasms |
| US6043224A (en) * | 1996-09-05 | 2000-03-28 | The Massachusetts Institute Of Technology | Compositions and methods for treatment of neurological disorders and neurodegenerative diseases |
| WO1998043619A2 (en) * | 1997-04-02 | 1998-10-08 | The Regents Of The University Of California | Method of local anesthesia |
| AU7389098A (en) * | 1997-05-16 | 1998-12-08 | Brigham And Women's Hospital | Local anesthetic formulations |
| KR100544060B1 (ko) * | 1997-07-15 | 2006-01-23 | 더 리젠트스 오브 더 유니버시티 오브 콜로라도 | 비뇨기과학 및 관련 부전증을 치료하기 위한 신경독요법의 용도 |
| US6432986B2 (en) * | 1997-07-21 | 2002-08-13 | Bruce H. Levin | Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches |
| US6159944A (en) * | 1998-02-27 | 2000-12-12 | Synchroneuron, Llc | Method for treating painful conditions of the anal region and compositions therefor |
| JP4289694B2 (ja) * | 1998-04-03 | 2009-07-01 | 正昭 児玉 | 新規のサキシトキシン誘導体およびその製造方法 |
| WO2000024419A1 (en) * | 1998-10-27 | 2000-05-04 | Mayo Foundation For Medical Education And Research | Methods for enhancing wound healing |
| US6265379B1 (en) * | 1999-10-13 | 2001-07-24 | Allergan Sales, Inc. | Method for treating otic disorders |
| US6143306A (en) * | 2000-01-11 | 2000-11-07 | Allergan Sales, Inc. | Methods for treating pancreatic disorders |
| US6261572B1 (en) * | 2000-01-11 | 2001-07-17 | Allergan Sales, Inc. | Method for treating a pancreatic disorder with a neurotoxin |
| US6337075B1 (en) * | 2000-01-11 | 2002-01-08 | Allergan Sales, Inc. | Methods for treating diabetes |
| US6464986B1 (en) * | 2000-04-14 | 2002-10-15 | Allegan Sales, Inc. | Method for treating pain by peripheral administration of a neurotoxin |
| US6299893B1 (en) * | 2000-04-17 | 2001-10-09 | Marvin Schwartz | Method to reduce hair loss and stimulate hair regrowth |
| US6306423B1 (en) * | 2000-06-02 | 2001-10-23 | Allergan Sales, Inc. | Neurotoxin implant |
| US6306403B1 (en) * | 2000-06-14 | 2001-10-23 | Allergan Sales, Inc. | Method for treating parkinson's disease with a botulinum toxin |
| CN1284536C (zh) * | 2000-09-18 | 2006-11-15 | 威克斯医药有限公司 | 河豚毒素或蛤蚌毒素及其类似物在制备用于全身镇痛的镇痛药中的应用 |
| CN1203857C (zh) * | 2000-09-18 | 2005-06-01 | 威克斯医药有限公司 | 局部麻醉与镇痛的新方法 |
| CN1240702C (zh) * | 2000-09-18 | 2006-02-08 | 威克斯医药有限公司 | 高获得率提取替曲朵辛的方法 |
| US6423319B1 (en) * | 2000-10-04 | 2002-07-23 | Allergan Sales, Inc. | Methods for treating muscle injuries |
| CN1236773C (zh) * | 2000-11-22 | 2006-01-18 | 南宁枫叶药业有限公司 | 用于镇痛、麻醉或治疗药物依赖性的制剂 |
| US20020086036A1 (en) * | 2000-12-05 | 2002-07-04 | Allergan Sales, Inc. | Methods for treating hyperhidrosis |
| CN1382443A (zh) * | 2001-04-25 | 2002-12-04 | 威克斯医疗仪器有限公司 | 钠离子通道阻断剂在制备用于局部神经麻醉或镇痛的药物中的应用 |
| CN1269482C (zh) * | 2001-05-18 | 2006-08-16 | 威克斯医药有限公司 | 钠离子通道阻断剂和阿片类镇痛剂在制备用于对哺乳动物进行协同镇痛的药物中的应用 |
| MXPA04004543A (es) * | 2001-11-15 | 2005-03-31 | Micro Algae Corp | Composiciones farmaceuticas que contienen 3,4-propinoperhidropurinas y sus usos para el bloqueo de la transmision neuronal. |
| US20030113349A1 (en) * | 2001-12-18 | 2003-06-19 | Coleman William P. | Topically applied clostridium botulinum toxin compositions and treatment methods |
| US20030224020A1 (en) | 2002-05-31 | 2003-12-04 | Zabudkin Alexander F. | Pharmaceutical preparation of botulinum neurotoxin, methods of synthesis and methods of clinical use |
| US20040009180A1 (en) * | 2002-07-11 | 2004-01-15 | Allergan, Inc. | Transdermal botulinum toxin compositions |
| AU2003298837A1 (en) * | 2002-12-02 | 2004-06-23 | Massachusetts Institute Of Technology | Prolonged suppression of electrical activity in excitable tissues |
| JP2007538010A (ja) * | 2004-05-07 | 2007-12-27 | ファイトトックス リミテッド | フィコトキシンの経皮投与 |
| JP2007536269A (ja) * | 2004-05-07 | 2007-12-13 | ファイトトックス リミテッド | ゴニオトキシンを用いた創傷の治療方法 |
-
2005
- 2005-05-06 JP JP2007511671A patent/JP2007536269A/ja active Pending
- 2005-05-06 CA CA2606530A patent/CA2606530C/en not_active Expired - Lifetime
- 2005-05-06 CN CN2005800227692A patent/CN1997373B/zh not_active Expired - Fee Related
- 2005-05-06 WO PCT/US2005/015946 patent/WO2005110417A1/en not_active Ceased
- 2005-05-06 ES ES05747904.0T patent/ES2646087T3/es not_active Expired - Lifetime
- 2005-05-06 US US11/568,750 patent/US20070280970A1/en not_active Abandoned
- 2005-05-06 AU AU2005244105A patent/AU2005244105B2/en not_active Ceased
- 2005-05-06 MX MXPA06012961A patent/MXPA06012961A/es unknown
- 2005-05-06 EP EP05743508A patent/EP1802250A4/en not_active Withdrawn
- 2005-05-06 CA CA2821239A patent/CA2821239C/en not_active Expired - Lifetime
- 2005-05-06 BR BRPI0510759-8A patent/BRPI0510759A/pt not_active IP Right Cessation
- 2005-05-06 US US11/568,752 patent/US20080021051A1/en not_active Abandoned
- 2005-05-06 EP EP05747904.0A patent/EP1824488B1/en not_active Expired - Lifetime
- 2005-05-06 AU AU2005244116A patent/AU2005244116C1/en not_active Ceased
- 2005-05-06 WO PCT/US2005/016021 patent/WO2005110275A1/en not_active Ceased
- 2005-05-06 MX MXPA06012962A patent/MXPA06012962A/es unknown
- 2005-05-06 BR BRPI0510761-0A patent/BRPI0510761A/pt not_active IP Right Cessation
- 2005-05-06 CA CA002607589A patent/CA2607589A1/en not_active Abandoned
- 2005-05-06 JP JP2007511659A patent/JP5047782B2/ja not_active Expired - Fee Related
-
2012
- 2012-06-19 US US13/526,868 patent/US8623886B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2646087T3 (es) | 2017-12-12 |
| CA2607589A1 (en) | 2005-11-24 |
| EP1824488B1 (en) | 2017-08-09 |
| MXPA06012962A (es) | 2007-06-12 |
| US8623886B2 (en) | 2014-01-07 |
| CA2606530A1 (en) | 2005-11-24 |
| AU2005244116B2 (en) | 2011-03-03 |
| AU2005244105B2 (en) | 2011-10-06 |
| AU2005244116B8 (en) | 2011-03-31 |
| EP1824488A4 (en) | 2008-07-02 |
| CA2606530C (en) | 2014-01-07 |
| US20070280970A1 (en) | 2007-12-06 |
| CN1997373B (zh) | 2010-12-22 |
| MXPA06012961A (es) | 2007-06-12 |
| WO2005110417A1 (en) | 2005-11-24 |
| EP1802250A4 (en) | 2008-07-02 |
| EP1824488A1 (en) | 2007-08-29 |
| CA2821239A1 (en) | 2005-11-24 |
| JP5047782B2 (ja) | 2012-10-10 |
| AU2005244116C1 (en) | 2011-09-29 |
| JP2007536264A (ja) | 2007-12-13 |
| US20120322818A1 (en) | 2012-12-20 |
| EP1802250A1 (en) | 2007-07-04 |
| CN1997373A (zh) | 2007-07-11 |
| US20080021051A1 (en) | 2008-01-24 |
| AU2005244116A1 (en) | 2005-11-24 |
| JP2007536269A (ja) | 2007-12-13 |
| AU2005244105A1 (en) | 2005-11-24 |
| CA2821239C (en) | 2016-04-12 |
| WO2005110417A8 (en) | 2006-12-21 |
| BRPI0510759A (pt) | 2007-11-20 |
| WO2005110275A1 (en) | 2005-11-24 |
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