BRPI0511137A - compostos opióides de carboxamido - Google Patents

compostos opióides de carboxamido

Info

Publication number
BRPI0511137A
BRPI0511137A BRPI0511137-4A BRPI0511137A BRPI0511137A BR PI0511137 A BRPI0511137 A BR PI0511137A BR PI0511137 A BRPI0511137 A BR PI0511137A BR PI0511137 A BRPI0511137 A BR PI0511137A
Authority
BR
Brazil
Prior art keywords
carboxamide
opioid compounds
compounds
modulation
treatment
Prior art date
Application number
BRPI0511137-4A
Other languages
English (en)
Inventor
John R Carson
Philip M Pitis
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35064532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0511137(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BRPI0511137A publication Critical patent/BRPI0511137A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPOSTOS OPIóIDES DE CARBOXAMIDO Esta invenção é dirigida a compostos opióides de carboxamido farmaceuticamente úteis como agentes para o tratamento ou para a modulação de um distúrbio do sistema nervoso central e a métodos para o tratamento ou para a modulação de um distúrbio do sistema nervoso central.
BRPI0511137-4A 2004-05-14 2005-05-11 compostos opióides de carboxamido BRPI0511137A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57129804P 2004-05-14 2004-05-14
PCT/US2005/016581 WO2005113486A1 (en) 2004-05-14 2005-05-11 Carboxamido opioid compounds

Publications (1)

Publication Number Publication Date
BRPI0511137A true BRPI0511137A (pt) 2007-11-27

Family

ID=35064532

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511137-4A BRPI0511137A (pt) 2004-05-14 2005-05-11 compostos opióides de carboxamido

Country Status (21)

Country Link
US (2) US7244866B2 (pt)
EP (1) EP1748978B1 (pt)
JP (1) JP5420170B2 (pt)
KR (1) KR101204751B1 (pt)
CN (1) CN1984879B (pt)
AR (1) AR049276A1 (pt)
AU (1) AU2005245403B2 (pt)
BR (1) BRPI0511137A (pt)
CA (1) CA2566601C (pt)
CR (1) CR8811A (pt)
EA (1) EA013261B1 (pt)
EC (1) ECSP067008A (pt)
ES (1) ES2485867T3 (pt)
IL (1) IL179196A (pt)
MX (1) MXPA06013270A (pt)
NO (1) NO20065768L (pt)
NZ (1) NZ551288A (pt)
TW (1) TWI418345B (pt)
UA (1) UA90432C2 (pt)
WO (1) WO2005113486A1 (pt)
ZA (1) ZA200610446B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060254029A1 (en) * 2005-05-11 2006-11-16 Conrad Swenson Pocket loss prevention device
MXPA06013270A (es) * 2004-05-14 2007-04-23 Johnson & Johnson Compuestos de opioide carboxamido.
MX2009012685A (es) * 2007-05-31 2009-12-14 Sepracor Inc Cicloalquilaminas sustituidas con fenilo como inhibidores de la reabsorcion de monoamina.
WO2010107457A1 (en) * 2009-03-19 2010-09-23 Alkermes, Inc. Morphinan derivatives with high oral bioavailability
HUE043963T2 (hu) * 2009-12-04 2019-09-30 Alkermes Pharma Ireland Ltd Morfinán származékok gyógyszer-túladagolás kezelésére
EP2608670B1 (en) 2010-08-23 2018-10-31 Alkermes Pharma Ireland Limited Methods for treating antipsychotic-induced weight gain
US9029543B2 (en) 2011-04-05 2015-05-12 Alkermes, Inc. Process for the synthesis of quaternary amine compounds
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
SMT201800664T1 (it) 2011-12-15 2019-01-11 Alkermes Pharma Ireland Ltd Samidorphan (alks 33) in combinazione con buprenorfina per il trattamento di disturbi depressivi
US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
ES2770978T3 (es) 2013-05-24 2020-07-06 Alkermes Pharma Ireland Ltd Análogos de morfanos y morfinanos y métodos de uso
CN104940709A (zh) * 2015-07-22 2015-09-30 张秋英 一种镇痛麻醉喷雾剂
CN105055756A (zh) * 2015-09-18 2015-11-18 张秋英 一种阴部挫伤用镇痛气雾剂
CN116751156A (zh) 2017-01-17 2023-09-15 梅比斯发现公司 取代的3-二烷基氨基甲基-哌啶-4-基-苯甲酰胺及其制备和使用方法
WO2022101444A1 (en) 2020-11-12 2022-05-19 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2071897A1 (en) 1989-12-28 1991-06-29 Richard A. Glennon Sigma receptor ligands and the use thereof
US6071970A (en) 1993-02-08 2000-06-06 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
ATE292625T1 (de) * 2000-10-31 2005-04-15 Rensselaer Polytech Inst 8-substituierte 2,6-methano-3-benzazocine und 3- substituierte morphinane als opioidrezeptorbindende agenzien
DE10059413A1 (de) * 2000-11-30 2002-06-20 Gruenenthal Gmbh Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10146275A1 (de) * 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
AU2002364517A1 (en) * 2001-11-30 2003-06-17 Sepracor Inc. Tramadol analogs and uses thereof
DE10213051B4 (de) 2002-03-23 2013-03-07 Grünenthal GmbH Substituierte 4-Aminocyclohexanole
AU2003275855B2 (en) * 2002-10-25 2009-04-23 Paladin Labs (Barbados) Inc. Sustained-release tramadol formulations with 24-hour efficacy
KR101166342B1 (ko) 2004-03-15 2012-07-18 얀센 파마슈티카 엔.브이. 아편계 약물 수용체 조절자로서의 신규의 화합물
MXPA06013270A (es) * 2004-05-14 2007-04-23 Johnson & Johnson Compuestos de opioide carboxamido.

Also Published As

Publication number Publication date
TW200605871A (en) 2006-02-16
NO20065768L (no) 2007-02-07
CA2566601A1 (en) 2005-12-01
AU2005245403A1 (en) 2005-12-01
UA90432C2 (uk) 2010-04-26
US20050256203A1 (en) 2005-11-17
AU2005245403B2 (en) 2012-04-19
IL179196A0 (en) 2007-03-08
WO2005113486A1 (en) 2005-12-01
CA2566601C (en) 2013-04-09
CN1984879B (zh) 2011-07-27
TWI418345B (zh) 2013-12-11
EA200602115A1 (ru) 2007-04-27
ECSP067008A (es) 2006-12-29
JP2007537278A (ja) 2007-12-20
US7745492B2 (en) 2010-06-29
AR049276A1 (es) 2006-07-12
NZ551288A (en) 2010-10-29
MXPA06013270A (es) 2007-04-23
KR20070015613A (ko) 2007-02-05
IL179196A (en) 2012-10-31
KR101204751B1 (ko) 2012-11-27
CN1984879A (zh) 2007-06-20
US7244866B2 (en) 2007-07-17
ZA200610446B (en) 2008-07-30
US20080280990A1 (en) 2008-11-13
EA013261B1 (ru) 2010-04-30
CR8811A (es) 2009-01-14
JP5420170B2 (ja) 2014-02-19
EP1748978B1 (en) 2014-06-04
ES2485867T3 (es) 2014-08-14
HK1101246A1 (en) 2007-10-12
EP1748978A1 (en) 2007-02-07

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]