UA90432C2 - Карбоксамідні опіоїдні сполуки - Google Patents

Карбоксамідні опіоїдні сполуки

Info

Publication number
UA90432C2
UA90432C2 UAA200612496A UAA200612496A UA90432C2 UA 90432 C2 UA90432 C2 UA 90432C2 UA A200612496 A UAA200612496 A UA A200612496A UA A200612496 A UAA200612496 A UA A200612496A UA 90432 C2 UA90432 C2 UA 90432C2
Authority
UA
Ukraine
Prior art keywords
opioid compounds
carboxamido
carboxamido opioid
modulating
treating
Prior art date
Application number
UAA200612496A
Other languages
English (en)
Russian (ru)
Inventor
Джон Р. Карсон
Філіп М. Пітіс
Original Assignee
Янссен Фармацевтика Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35064532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA90432(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Янссен Фармацевтика Н.В. filed Critical Янссен Фармацевтика Н.В.
Publication of UA90432C2 publication Critical patent/UA90432C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Даний винахід стосується карбоксамідних опіоїдних сполук, які є фармацевтично корисними як агенти для лікування або модуляції розладу центральної нервової системи, та способів лікування або модуляції розладу центральної нервової системи.
UAA200612496A 2004-05-14 2005-11-05 Карбоксамідні опіоїдні сполуки UA90432C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57129804P 2004-05-14 2004-05-14
PCT/US2005/016581 WO2005113486A1 (en) 2004-05-14 2005-05-11 Carboxamido opioid compounds

Publications (1)

Publication Number Publication Date
UA90432C2 true UA90432C2 (uk) 2010-04-26

Family

ID=35064532

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200612496A UA90432C2 (uk) 2004-05-14 2005-11-05 Карбоксамідні опіоїдні сполуки

Country Status (21)

Country Link
US (2) US7244866B2 (uk)
EP (1) EP1748978B1 (uk)
JP (1) JP5420170B2 (uk)
KR (1) KR101204751B1 (uk)
CN (1) CN1984879B (uk)
AR (1) AR049276A1 (uk)
AU (1) AU2005245403B2 (uk)
BR (1) BRPI0511137A (uk)
CA (1) CA2566601C (uk)
CR (1) CR8811A (uk)
EA (1) EA013261B1 (uk)
EC (1) ECSP067008A (uk)
ES (1) ES2485867T3 (uk)
IL (1) IL179196A (uk)
MX (1) MXPA06013270A (uk)
NO (1) NO20065768L (uk)
NZ (1) NZ551288A (uk)
TW (1) TWI418345B (uk)
UA (1) UA90432C2 (uk)
WO (1) WO2005113486A1 (uk)
ZA (1) ZA200610446B (uk)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2485867T3 (es) * 2004-05-14 2014-08-14 Janssen Pharmaceutica Nv Compuestos opioides de carboxamido
US20060254029A1 (en) * 2005-05-11 2006-11-16 Conrad Swenson Pocket loss prevention device
WO2008151156A1 (en) * 2007-05-31 2008-12-11 Sepracor Inc. Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors
EP2408303A4 (en) * 2009-03-19 2012-07-25 Alkermes Inc MORPHINANE DERIVATIVES HAVING HIGH ORAL BIOLOGICAL AVAILABILITY
AU2010326676B2 (en) * 2009-12-04 2013-03-14 Alkermes Pharma Ireland Limited Morphinan derivatives for the treatment of drug overdose
PL3446565T3 (pl) 2010-08-23 2024-04-02 Alkermes Pharma Ireland Limited Sposoby leczenia przyrostu masy ciała wywołanego lekami przeciwpsychotycznymi
US9029543B2 (en) 2011-04-05 2015-05-12 Alkermes, Inc. Process for the synthesis of quaternary amine compounds
PL3153171T3 (pl) 2011-12-15 2019-02-28 Alkermes Pharma Ireland Limited Samidorfan (alks 33) w połączeniu z buprenorfiną do leczenia zaburzeń depresyjnych
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
WO2014190270A1 (en) 2013-05-24 2014-11-27 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
CN104940709A (zh) * 2015-07-22 2015-09-30 张秋英 一种镇痛麻醉喷雾剂
CN105055756A (zh) * 2015-09-18 2015-11-18 张秋英 一种阴部挫伤用镇痛气雾剂
WO2018136546A1 (en) 2017-01-17 2018-07-26 Mebias Discovery Llc Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU658134B2 (en) * 1989-12-28 1995-04-06 Virginia Commonwealth University Sigma receptor ligands and the use thereof
US6071970A (en) * 1993-02-08 2000-06-06 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
EP1359146B1 (en) * 2000-10-31 2008-04-09 Rensselaer Polytechnic Institute 4-aryl piperidines as opioid receptor binding agents
DE10059413A1 (de) * 2000-11-30 2002-06-20 Gruenenthal Gmbh Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10146275A1 (de) * 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
WO2003048113A1 (en) 2001-11-30 2003-06-12 Sepracor Inc. Tramadol analogs and uses thereof
DE10213051B4 (de) 2002-03-23 2013-03-07 Grünenthal GmbH Substituierte 4-Aminocyclohexanole
WO2004037222A2 (en) * 2002-10-25 2004-05-06 Labopharm Inc. Sustained-release tramadol formulations with 24-hour efficacy
HUE029852T2 (en) 2004-03-15 2017-04-28 Janssen Pharmaceutica Nv Opioid receptor modulators
ES2485867T3 (es) * 2004-05-14 2014-08-14 Janssen Pharmaceutica Nv Compuestos opioides de carboxamido

Also Published As

Publication number Publication date
WO2005113486A1 (en) 2005-12-01
AU2005245403A1 (en) 2005-12-01
CA2566601A1 (en) 2005-12-01
US7745492B2 (en) 2010-06-29
JP5420170B2 (ja) 2014-02-19
TWI418345B (zh) 2013-12-11
US7244866B2 (en) 2007-07-17
JP2007537278A (ja) 2007-12-20
ZA200610446B (en) 2008-07-30
ECSP067008A (es) 2006-12-29
AR049276A1 (es) 2006-07-12
US20080280990A1 (en) 2008-11-13
IL179196A0 (en) 2007-03-08
EA013261B1 (ru) 2010-04-30
CA2566601C (en) 2013-04-09
NO20065768L (no) 2007-02-07
KR101204751B1 (ko) 2012-11-27
TW200605871A (en) 2006-02-16
CR8811A (es) 2009-01-14
ES2485867T3 (es) 2014-08-14
CN1984879A (zh) 2007-06-20
BRPI0511137A (pt) 2007-11-27
AU2005245403B2 (en) 2012-04-19
HK1101246A1 (en) 2007-10-12
EA200602115A1 (ru) 2007-04-27
NZ551288A (en) 2010-10-29
US20050256203A1 (en) 2005-11-17
MXPA06013270A (es) 2007-04-23
EP1748978B1 (en) 2014-06-04
KR20070015613A (ko) 2007-02-05
IL179196A (en) 2012-10-31
EP1748978A1 (en) 2007-02-07
CN1984879B (zh) 2011-07-27

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