BRPI0511372A - seleção e uso de bactérias de ácido lático para redução de cárie dentária e de bactérias causadoras da cárie dentária - Google Patents

seleção e uso de bactérias de ácido lático para redução de cárie dentária e de bactérias causadoras da cárie dentária

Info

Publication number
BRPI0511372A
BRPI0511372A BRPI0511372-5A BRPI0511372A BRPI0511372A BR PI0511372 A BRPI0511372 A BR PI0511372A BR PI0511372 A BRPI0511372 A BR PI0511372A BR PI0511372 A BRPI0511372 A BR PI0511372A
Authority
BR
Brazil
Prior art keywords
tooth decay
bacteria
selection
lactic acid
acid bacteria
Prior art date
Application number
BRPI0511372-5A
Other languages
English (en)
Inventor
Eamonn Connolly
Bo Moellstam
Original Assignee
Biogaia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogaia Ab filed Critical Biogaia Ab
Publication of BRPI0511372A publication Critical patent/BRPI0511372A/pt
Publication of BRPI0511372B1 publication Critical patent/BRPI0511372B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/366—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing microorganisms, enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/12—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/12—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G4/123—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing microorganisms, enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C2260/00—Particular aspects or types of dairy products
    • A23C2260/25—Dairy compositions providing for tooth protective effects, e.g. anticariogenic effects
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/173—Reuteri
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

SELEçãO E USO DE BACTéRIAS DE áCIDO LáTICO PARA REDUçãO DE CáRIE DENTáRIA E DE BACTéRIAS CAUSADORAS DA CáRIE DENTáRIA. Novas linhagens de Lactobacilius que foram selecionadas por sua capacidade de redução aprimorada do número de Streptococcus mutans na boca de mamíferos por meio da atividade de inibição, em combinação com ligação melhor às mucinas orais e à placa dentária, prevenindo, reduzindo ou tratando a cárie dentária, e produtos derivados dessas linhagens citadas, incluindo agentes para tratamento ou profilaxia de cárie para administração em humanos.
BRPI0511372-5A 2004-06-14 2005-05-30 Produto para inibição do crescimento de bactérias de cárie dentária, e, método para fabricar um produto BRPI0511372B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/869,185 2004-06-14
US10/869,185 US7517681B2 (en) 2003-01-29 2004-06-14 Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries
PCT/SE2005/000805 WO2005121312A1 (en) 2004-06-14 2005-05-30 Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries

Publications (2)

Publication Number Publication Date
BRPI0511372A true BRPI0511372A (pt) 2007-12-04
BRPI0511372B1 BRPI0511372B1 (pt) 2020-09-15

Family

ID=35503056

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511372-5A BRPI0511372B1 (pt) 2004-06-14 2005-05-30 Produto para inibição do crescimento de bactérias de cárie dentária, e, método para fabricar um produto

Country Status (14)

Country Link
US (1) US7517681B2 (pt)
EP (1) EP1765975A1 (pt)
JP (2) JP5566007B2 (pt)
KR (2) KR101261172B1 (pt)
CN (1) CN1981028A (pt)
AU (1) AU2005252605B2 (pt)
BR (1) BRPI0511372B1 (pt)
CA (1) CA2569141C (pt)
IN (2) IN244537B (pt)
MX (1) MX287430B (pt)
NZ (1) NZ552585A (pt)
SG (1) SG128035A1 (pt)
WO (1) WO2005121312A1 (pt)
ZA (1) ZA200700210B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7517681B2 (en) * 2003-01-29 2009-04-14 Biogaia Ab Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries
CN101273736B (zh) * 2007-03-28 2012-08-08 北京弗蒙特生物技术有限公司 一种在常温下保持高活菌数的发酵乳的制备方法
JP2012500643A (ja) * 2008-08-28 2012-01-12 セーホーエル．ハンセン アクティーゼルスカブ 細菌組成物
ES2592882T3 (es) * 2008-10-14 2016-12-02 Mcneil Ab Forma de dosificación intra-oral de múltiples porciones y uso de la misma
JP5645192B2 (ja) 2009-07-16 2014-12-24 国立大学法人広島大学 口腔内疾患の予防、改善又は治療剤
US20110293710A1 (en) * 2010-02-02 2011-12-01 Delphine Saulnier Immunomodulatory properties of lactobacillus strains
IT1398648B1 (it) * 2010-03-09 2013-03-08 Probiotical Spa Prodotto alimentare comprendente batteri probiotici rivestiti con un rivestimento di origine vegetale.
JP2012092094A (ja) * 2010-09-30 2012-05-17 Wakamoto Pharmaceutical Co Ltd 油脂中に乳酸菌を含有する口腔用組成物
GB201206599D0 (en) 2012-04-13 2012-05-30 Univ Manchester Probiotic bacteria
WO2014171478A1 (ja) 2013-04-17 2014-10-23 サントリーホールディングス株式会社 ラクトバチルス属菌含有組成物
NZ712617A (en) * 2013-04-17 2020-02-28 Suntory Holdings Ltd Bacterium belonging to genus lactobacillus
CN103478390B (zh) * 2013-08-13 2015-04-15 华侨大学 一种预防和辅助治疗牙周炎的口香糖的制备方法
KR102095339B1 (ko) * 2017-06-01 2020-05-27 한국생명공학연구원 신규한 락토바실러스 류테리 균주 및 이를 유효성분으로 포함하는 치주질환 예방 또는 치료용 조성물
KR101966772B1 (ko) * 2017-07-11 2019-04-09 주식회사 다케어 락토바실러스 루테리 cs 132(kctc 11452bp) 또는 이의 배양물을 포함하는 구강병원균 억제조성물
KR102001074B1 (ko) * 2018-12-07 2019-07-18 주식회사 메디오젠 충치 억제 활성을 갖는 유산균 조성물
KR102210092B1 (ko) * 2019-07-09 2021-02-01 주식회사 메디오젠 충치 억제 활성을 갖는 락토바실러스 루테리 mg505 를 포함하는 조성물
KR102230517B1 (ko) * 2019-07-09 2021-03-22 주식회사 메디오젠 충치 억제 활성을 갖는 락토바실러스 살리바리우스를 포함하는 조성물
IT202100000176A1 (it) * 2021-01-07 2022-07-07 Metis Healthcare S R L Preparazioni orali a base di carnosina ad attività antivirale
KR102736620B1 (ko) * 2021-06-23 2024-12-03 주식회사 웰빙엘에스 스트렙토코커스 뮤탄스 억제 및 항염증 효능을 갖는 신규한 락토바실러스 애시도필러스 균주 및 이의 용도
CN113652340A (zh) * 2021-08-24 2021-11-16 江苏江大源生态生物科技股份有限公司 一种益生菌制剂、菌种筛选装置及筛选方法
CA3228922A1 (en) 2021-10-11 2023-04-20 Ajinomoto Co., Inc. Bacterium modified to express heterologous tat protein
JP2023172607A (ja) * 2022-05-24 2023-12-06 株式会社アデランス 乳酸菌含有ガム
CN116650390A (zh) * 2023-02-01 2023-08-29 苏州抓马生物科技有限公司 一种专效修复抗敏的无水配方牙膏
KR102637772B1 (ko) 2023-09-21 2024-02-20 주식회사 큐옴바이오 위건강과 구강질환 관련 미생물 및 병원성 미생물에 대한 항균활성을 갖는 산삼 유래 락토바실러스 플란타럼 wg.q7 균주 및 이의 용도

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH637297A5 (fr) * 1978-12-05 1983-07-29 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication.
EP0154549B1 (en) * 1984-03-09 1990-12-27 Kabushiki Kaisya Advance Anticariogenic or antiperiodontitic agent
US5413960A (en) * 1987-05-01 1995-05-09 Biogaia Ab Antibiotic reuterin
FR2672494A1 (fr) 1991-02-13 1992-08-14 Madinier Isabelle Ferments prophylactiques favorisant la prevention de la carie dentaire.
WO1997022353A1 (en) * 1995-12-21 1997-06-26 Abbott Laboratories Use of lactobacillus reuteri to inhibit cryptosporidiosis in mammals
US5837238A (en) * 1996-06-05 1998-11-17 Biogaia Biologics Ab Treatment of diarrhea
US5800813A (en) * 1996-11-12 1998-09-01 Biogaia Biologics Ab Treatment of cryptosporidium infections
KR19990024297A (ko) * 1997-08-07 1999-04-06 오종석 인체 구강내 치태형성을 억제하는 신규한 유산균
US6100388A (en) * 1998-03-16 2000-08-08 Biogaia Biologies Ab Lactobacilli harboring aggregation gene as a vaccine delivery vehicle
US6461607B1 (en) * 1998-08-24 2002-10-08 Ganeden Biotech, Inc. Probiotic, lactic acid-producing bacteria and uses thereof
GB9920578D0 (en) 1999-08-31 1999-11-03 Nestle Sa Composition for maintenance of bone or dental health or treatment of bone or dental disorders
JP3824312B2 (ja) * 2000-05-02 2006-09-20 ビオフェルミン製薬株式会社 噴霧乾燥による菌体乾燥物
JP3363438B2 (ja) * 2000-05-02 2003-01-08 ビオフェルミン製薬株式会社 噴霧乾燥による菌体乾燥物
JP2003299480A (ja) * 2002-04-09 2003-10-21 Hiroki Futagawa 虫歯予防用細菌、虫歯予防用食品、虫歯予防用口腔洗浄剤及びヨーグルトの製造方法
US7517681B2 (en) * 2003-01-29 2009-04-14 Biogaia Ab Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries
US6872565B2 (en) * 2003-01-29 2005-03-29 Biogaia Ab Product containing Lactobacillus reuteri strain ATTC PTA-4965 or PTA-4964 for inhibiting bacteria causing dental caries

Also Published As

Publication number Publication date
JP2008502360A (ja) 2008-01-31
JP2012130358A (ja) 2012-07-12
KR101261172B1 (ko) 2013-05-09
ZA200700210B (en) 2008-05-28
BRPI0511372B1 (pt) 2020-09-15
CN1981028A (zh) 2007-06-13
CA2569141A1 (en) 2005-12-22
NZ552585A (en) 2009-08-28
EP1765975A1 (en) 2007-03-28
JP5566007B2 (ja) 2014-08-06
IN244537B (pt) 2010-12-17
SG128035A1 (en) 2007-01-30
MXPA06014516A (es) 2007-03-12
WO2005121312A1 (en) 2005-12-22
US20050002874A1 (en) 2005-01-06
AU2005252605B2 (en) 2010-08-12
KR101143734B1 (ko) 2012-05-10
MX287430B (es) 2011-06-13
US7517681B2 (en) 2009-04-14
AU2005252605A1 (en) 2005-12-22
KR20070030819A (ko) 2007-03-16
IN2006DE07653A (en) 2007-08-17
CA2569141C (en) 2012-05-29
KR20110093951A (ko) 2011-08-18

Similar Documents

Publication Publication Date Title
BRPI0511372A (pt) seleção e uso de bactérias de ácido lático para redução de cárie dentária e de bactérias causadoras da cárie dentária
Ramamurthy et al. Comparison of effect of Hiora mouthwash versus Chlorhexidine mouthwash in gingivitis patients: A clinical trial
Shah et al. Comparative evaluation of plaque inhibitory and antimicrobial efficacy of probiotic and chlorhexidine oral rinses in orthodontic patients: a randomized clinical trial
Cummins The development and validation of a new technology, based upon 1.5% arginine, an insoluble calcium compound and fluoride, for everyday use in the prevention and treatment of dental caries
Morawiec et al. The biological activity of propolis‐containing toothpaste on oral health environment in patients who underwent implant‐supported prosthodontic rehabilitation
Arora et al. Efficacy of dental floss and chlorhexidine mouth rinse as an adjunct to toothbrushing in removing plaque and gingival inflammation–A three way cross over trial
Albert‐Kiszely et al. Comparison of the effects of cetylpyridinium chloride with an essential oil mouth rinse on dental plaque and gingivitis–A six‐month randomized controlled clinical trial
Caufield et al. The antimicrobial approach to caries management
Hajiahmadi et al. Comparative evaluation of antibacterial effect of propolis and aloe vera, xylitol, and Cpp‐Acp gels on streptococcus mutans and lactobacillus in vitro
BR0318706A (pt) composição herbárea para cuidados oro-dentais e processo para preparar a mesma
Syed et al. Comparative evaluation of 0.2% chlorhexidine mouthwash, xylitol chewing gum, and combination of 0.2% chlorhexidine mouthwash and xylitol chewing gum on salivary Streptococcus mutans and biofilm levels in 8-to 12-year-old children
Moreira et al. Comparison between full‐mouth scaling and root planing and quadrant‐wise basic therapy of aggressive periodontitis: 6‐month clinical results
Chen et al. The effects of natural compounds‐containing mouthrinses on patients with fixed orthodontic appliance treatment: clinical and microbiological outcomes
Gehlen et al. The influence of a 0.2% chlorhexidine mouthrinse on plaque regrowth in orthodontic patients: A randomized prospective study part II: Bacteriological parameters
Saini A prospective experimental comparative study on the clinical effects of calculus dissolution based oral rinse in gingivitis patients
Raina et al. A comparison of antibacterial efficacy of 0.5% sodium fluoride impregnated miswak and plain miswak sticks on Streprococcus mutans-A randomized controlled trial
Hatti et al. Biofilm inhibition and antimicrobial activity of a dentifrice containing salivary substitutes
Ayesha et al. Comparison of the antimicrobial activity of aloevera mouthwash with chlorhexidine mouthwash in fixed orthodontic patients
Maruo et al. Effect of chlorhexidine mouth rinse on Streptococci counts of tooth‐tissue‐borne palatal expander biofilm
Semyari et al. Evaluation of antimicrobial effect of Ammi visnaga against oral streptococci
BR0111371A (pt) Uso de um gênero de bactéria láctica exógena contra doenças actinomyces naeslundii-relacionadas
Oak et al. A randomized double-blind clinical trial evaluates the efficacy of alternative herbal mouthwashes
Sabharwal et al. Baking soda dentifrice and periodontal health: A review of the literature
Shirozaki et al. Quantification of Streptococcus mutans in different types of ligature wires and elastomeric chains
Fard et al. Effectiveness of mouth washes on streptococci in plaque around orthodontic appliances

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: C12N 1/20 (2006.01), A61K 35/747 (2015.01), A61P 1

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 15/09/2020, OBSERVADAS AS CONDICOES LEGAIS.