BRPI0511390A - tiazolinona quinolinas não-substituìdas - Google Patents

tiazolinona quinolinas não-substituìdas

Info

Publication number
BRPI0511390A
BRPI0511390A BRPI0511390-3A BRPI0511390A BRPI0511390A BR PI0511390 A BRPI0511390 A BR PI0511390A BR PI0511390 A BRPI0511390 A BR PI0511390A BR PI0511390 A BRPI0511390 A BR PI0511390A
Authority
BR
Brazil
Prior art keywords
thiazolinone
quinolines
unsubstituted
compounds
quinoline
Prior art date
Application number
BRPI0511390-3A
Other languages
English (en)
Inventor
Shaoqing Chen
Li Chen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35262226&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0511390(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0511390A publication Critical patent/BRPI0511390A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

TIAZOLINONA QUINOLINAS NãO-SUBSTITUìDAS. A presente invenção refere-se a derivados de tiazolinona quinolina da fórmula (I) não tendo nenhuma substituição no anel quinolina e sendo ativos como inibidores de CDK1; a processos para a fabricação dos ditos compostos bem como o uso dos ditos compostos para a produção de medicamentos.
BRPI0511390-3A 2004-07-01 2005-06-23 tiazolinona quinolinas não-substituìdas BRPI0511390A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58474604P 2004-07-01 2004-07-01
US62949504P 2004-11-19 2004-11-19
PCT/EP2005/006807 WO2006002829A1 (en) 2004-07-01 2005-06-23 Thiazolinone unsubstituted quinolines

Publications (1)

Publication Number Publication Date
BRPI0511390A true BRPI0511390A (pt) 2007-12-04

Family

ID=35262226

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511390-3A BRPI0511390A (pt) 2004-07-01 2005-06-23 tiazolinona quinolinas não-substituìdas

Country Status (15)

Country Link
US (1) US7326786B2 (pt)
EP (1) EP1765817A1 (pt)
JP (1) JP2008504324A (pt)
KR (1) KR100866298B1 (pt)
CN (1) CN1984909A (pt)
AR (1) AR050165A1 (pt)
AU (1) AU2005259512A1 (pt)
BR (1) BRPI0511390A (pt)
CA (1) CA2571738A1 (pt)
IL (1) IL180313A0 (pt)
MX (1) MXPA06015028A (pt)
NO (1) NO20070564L (pt)
RU (1) RU2007103709A (pt)
TW (1) TW200612942A (pt)
WO (1) WO2006002829A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200716132A (en) * 2005-05-03 2007-05-01 Smithkline Beecham Corp Novel chemical compounds
US20090203692A1 (en) * 2005-05-23 2009-08-13 Smithkline Beecham Corporation Novel chemical compounds
PE20070083A1 (es) * 2005-06-08 2007-01-27 Smithkline Beecham Corp (5z)-5-(6-quinoxalinilmetilideno)-2-[(2,6-diclorofenil)amino]-1,3-tiazol-4(5h)-ona
US20090156644A1 (en) * 2005-07-21 2009-06-18 Jacob Westman Use of thiazole derivatives and analogues in the treatment of cancer
TW200745066A (en) 2005-09-16 2007-12-16 Torrent Pharmaceuticals Ltd Novel PTP1B inhibitors
WO2007103758A2 (en) * 2006-03-02 2007-09-13 Smithkline Beecham Corporation Thiazolones for use as pi3 kinase inhibitors
US20100286041A1 (en) * 2007-03-22 2010-11-11 Smithkline Beecham Corporation (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one
WO2010086613A1 (en) 2009-01-30 2010-08-05 Betagenon Ab Compounds useful as inhibitors as ampk
JP5679855B2 (ja) * 2011-02-14 2015-03-04 国立大学法人群馬大学 ジフルオロメチル化ヘテロアリール化合物の製造方法
CN104016942B (zh) * 2014-06-16 2016-02-24 天津医科大学 噻唑啉酮类衍生物及其药物组合物与应用
CN106831451B (zh) * 2017-02-03 2018-09-21 荆楚理工学院 一种2-氨基异丁醇的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1215208B1 (en) * 1997-10-27 2006-07-12 Agouron Pharmaceuticals, Inc. 4-Aminothiazole derivatives, their preparation and their use as inhibitors of cyclin-dependent kinases
EP1087951B9 (en) * 1998-06-18 2006-09-13 Bristol-Myers Squibb Company Carbon substituted aminothiazole inhibitors of cyclin dependent kinases
CN100579978C (zh) * 2002-11-22 2010-01-13 史密丝克莱恩比彻姆公司 化合物
ES2328146T3 (es) * 2003-07-28 2009-11-10 Merck Serono Sa 2-imino-4-(tio)oxo-5-policiclovinilazolinas para su uso como inhibidores de p13 quinasas.

Also Published As

Publication number Publication date
AU2005259512A1 (en) 2006-01-12
US7326786B2 (en) 2008-02-05
AR050165A1 (es) 2006-10-04
WO2006002829A1 (en) 2006-01-12
US20060004045A1 (en) 2006-01-05
EP1765817A1 (en) 2007-03-28
RU2007103709A (ru) 2008-08-10
IL180313A0 (en) 2007-06-03
NO20070564L (no) 2007-03-15
CN1984909A (zh) 2007-06-20
MXPA06015028A (es) 2007-02-08
JP2008504324A (ja) 2008-02-14
KR100866298B1 (ko) 2008-10-31
TW200612942A (en) 2006-05-01
KR20070024679A (ko) 2007-03-02
CA2571738A1 (en) 2006-01-12

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.