BRPI0513278A - uso de um composto, composto, composição farmacêutica, processo para produzir um composto, e, método para causar a morte celular através de terapia de ativação por fóton - Google Patents

uso de um composto, composto, composição farmacêutica, processo para produzir um composto, e, método para causar a morte celular através de terapia de ativação por fóton

Info

Publication number
BRPI0513278A
BRPI0513278A BRPI0513278-9A BRPI0513278A BRPI0513278A BR PI0513278 A BRPI0513278 A BR PI0513278A BR PI0513278 A BRPI0513278 A BR PI0513278A BR PI0513278 A BRPI0513278 A BR PI0513278A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
cell death
producing
activation therapy
Prior art date
Application number
BRPI0513278-9A
Other languages
English (en)
Inventor
Bipin Chandra Muljibhai Patel
Original Assignee
Psimei Pharmaceuticals Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Psimei Pharmaceuticals Plc filed Critical Psimei Pharmaceuticals Plc
Publication of BRPI0513278A publication Critical patent/BRPI0513278A/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

USO DE UM COMPOSTO, COMPOSTO, COMPOSIçãO FARMACêUTICA, PROCESSO PARA PRODUZIR UM COMPOSTO, E, MéTODO PARA CAUSAR A MORTE CELULAR ATRAVéS TERAPIA DE ATIVAçãO POR FóTON A presente invenção refere-se ao uso de um composto da fórmula (I) na manufatura de uma composição farmacêutica para a morte celular por terapia de ativação por fóton e o uso dos compostos na prevenção e/ ou tratamento de câncer.
BRPI0513278-9A 2004-07-13 2005-07-08 uso de um composto, composto, composição farmacêutica, processo para produzir um composto, e, método para causar a morte celular através de terapia de ativação por fóton BRPI0513278A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0415663.4A GB0415663D0 (en) 2004-07-13 2004-07-13 Compound
PCT/GB2005/002693 WO2006005924A1 (en) 2004-07-13 2005-07-08 Porphyrin derivatives and their use in photon activation therapy

Publications (1)

Publication Number Publication Date
BRPI0513278A true BRPI0513278A (pt) 2008-05-06

Family

ID=32893498

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513278-9A BRPI0513278A (pt) 2004-07-13 2005-07-08 uso de um composto, composto, composição farmacêutica, processo para produzir um composto, e, método para causar a morte celular através de terapia de ativação por fóton

Country Status (12)

Country Link
US (1) US7816518B2 (pt)
EP (1) EP1773324B1 (pt)
JP (1) JP2008506675A (pt)
KR (1) KR20070054636A (pt)
CN (1) CN101018551A (pt)
AU (1) AU2005261561A1 (pt)
BR (1) BRPI0513278A (pt)
CA (1) CA2573609A1 (pt)
GB (2) GB0415663D0 (pt)
RU (1) RU2007105233A (pt)
WO (1) WO2006005924A1 (pt)
ZA (1) ZA200701175B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0415663D0 (en) 2004-07-13 2004-08-18 Psimei Pharmaceuticals Plc Compound
JPWO2006112362A1 (ja) * 2005-04-18 2008-12-11 前田　浩 高分子型癌治療用医薬の製造方法
US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8324342B1 (en) * 2007-06-13 2012-12-04 Sandia Corporation Porphyrin coordination polymer nanospheres and nanorods
CL2009000393A1 (es) 2008-02-21 2010-01-04 Duke Univ Y Immunolight Llc Composición farmaceutica que comprende a) un agente farmaceutico activable, b) un agente activo plasmonico; util para el tratamiento de trastornos de proliferación celular.
US9907976B2 (en) 2011-07-08 2018-03-06 Immunolight, Llc Phosphors and scintillators for light stimulation within a medium
CN105288619A (zh) 2008-04-04 2016-02-03 免疫之光有限责任公司 用于原位光生物调节的非侵入性系统和方法
WO2009129321A1 (en) * 2008-04-18 2009-10-22 Sonnemed Llc Compounds and methods for activated therapy
EP2367914A4 (en) * 2008-11-17 2013-05-01 Xyleco Inc TREATMENT OF BIOMASS
JPWO2011099602A1 (ja) * 2010-02-12 2013-06-17 学校法人日本大学 ポルフィリン誘導体および放射線力学療法におけるその使用
DK2625180T3 (en) * 2010-10-06 2016-06-06 Aeolus Sciences Inc Porphyrinbehandling neurodegenerative diseases
DE102010056443A1 (de) * 2010-12-28 2012-06-28 Universität Bremen Chlorin-Derivate und deren Verwendung
CN102499924B (zh) * 2011-11-23 2013-07-24 中国医学科学院生物医学工程研究所 二乙撑三胺五乙酸或乙二胺四乙酸或胺三乙酸修饰卟啉的用途
GB201208548D0 (en) 2012-05-15 2012-06-27 Pci Biotech As Compound and method
EP3061762A1 (en) * 2015-02-26 2016-08-31 Universiteit van Amsterdam Photosensitizers
CN105503918A (zh) * 2015-12-08 2016-04-20 南京林业大学 一种含二氧杂戊硼基卟啉锌配合物及其制备方法
WO2019117457A1 (ko) 2017-12-12 2019-06-20 한국과학기술원 다공성 포르피린 고분자 및 이를 이용한 귀금속 원소의 회수 방법
KR102193582B1 (ko) * 2017-12-12 2020-12-22 한국과학기술원 다공성 포르피린 고분자 및 이를 이용한 귀금속 원소의 회수 방법
CN109679110B (zh) * 2018-12-25 2020-10-09 北京科技大学 一种基于菌绿素的纳米金属-有机框架光敏剂及制备方法
CN110684531B (zh) * 2019-10-09 2022-04-01 浙江理工大学 一种二硫化钼量子点负载四苯基锆卟啉纳米片的光敏传感材料的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5489716A (en) 1987-01-02 1996-02-06 Sun Company, Inc. (R&M) Reactions catalyzed by haloporphyrins
US4959356A (en) * 1989-05-26 1990-09-25 The United States Of America As Represented By The United States Department Of Energy Porphyrins for boron neutron capture therapy
JP3191223B2 (ja) * 1991-10-04 2001-07-23 株式会社光ケミカル研究所 ポルフィリン誘導体とその用途
JP3253663B2 (ja) * 1992-01-20 2002-02-04 タマ生化学株式会社 放射線増感剤
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use
HU224176B1 (hu) * 1997-05-07 2005-06-28 The University Of British Columbia A benzoporfirinszármazék fotoaktív vegyületek új osztálya
JP2004532251A (ja) 2001-05-31 2004-10-21 ミラヴァント ファーマシューティカルズ インコーポレイテッド 光線力学療法で使用のメタロテトラピロール系光増感剤
CA2449316A1 (en) 2001-06-06 2002-12-12 Brookhaven Science Associates Novel metalloporphyrins and their uses as radiosensitizers for radiation therapy
GB0227259D0 (en) 2002-11-21 2002-12-31 Photobiotics Ltd Porphyrin derivatives
US7378520B2 (en) 2004-07-08 2008-05-27 North Carolina State University Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers
GB0415663D0 (en) 2004-07-13 2004-08-18 Psimei Pharmaceuticals Plc Compound

Also Published As

Publication number Publication date
CN101018551A (zh) 2007-08-15
GB2433070A (en) 2007-06-13
GB0702696D0 (en) 2007-03-21
GB0415663D0 (en) 2004-08-18
ZA200701175B (en) 2008-11-26
KR20070054636A (ko) 2007-05-29
EP1773324B1 (en) 2015-04-01
US20080039436A1 (en) 2008-02-14
AU2005261561A1 (en) 2006-01-19
EP1773324A1 (en) 2007-04-18
JP2008506675A (ja) 2008-03-06
US7816518B2 (en) 2010-10-19
WO2006005924A1 (en) 2006-01-19
CA2573609A1 (en) 2006-01-19
RU2007105233A (ru) 2008-08-20

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