BRPI0513343A - sìntese bioquìmica de 1,4-butanodiamina - Google Patents
sìntese bioquìmica de 1,4-butanodiaminaInfo
- Publication number
- BRPI0513343A BRPI0513343A BRPI0513343-2A BRPI0513343A BRPI0513343A BR PI0513343 A BRPI0513343 A BR PI0513343A BR PI0513343 A BRPI0513343 A BR PI0513343A BR PI0513343 A BRPI0513343 A BR PI0513343A
- Authority
- BR
- Brazil
- Prior art keywords
- activity
- butanediamine
- biochemical synthesis
- microorganism
- compared
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
SìNTESE BIOQUìMICA DE 1,4-BUTANODIAMINA. A invenção é relacionada a um processo de síntese bioquímica de 1,4-butanodiamina em um microrganismo que apresenta um elevado nível de atividade de ornitina decarboxilase (atividade ODC aumentada) quando comparada aos níveis nativos de atividade ornitina decarboxilase, que ainda no microrganismo também uma atividade elevada na formação de N-acetilglutamato é presente como comparado aos níveis nativos de atividade de formação de N-acetilglutamato e ainda que a 1,4-butanodiamina produzida no microrganismo é excretada num caldo de fermentação, e é envolto do mesmo. A invenção também se relaciona aos vetores, plasmídeos e hospedeiros que apresentam um aumento correspondente de atividade ODC e um aumento na atividade de formação de N-acetilglutamato.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04077046.3 | 2004-07-15 | ||
| EP04077046 | 2004-07-15 | ||
| PCT/EP2005/007606 WO2006005603A1 (en) | 2004-07-15 | 2005-07-11 | Biochemical synthesis of 1,4-butanediamine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0513343A true BRPI0513343A (pt) | 2008-05-06 |
| BRPI0513343B1 BRPI0513343B1 (pt) | 2020-11-03 |
Family
ID=34928370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0513343-2A BRPI0513343B1 (pt) | 2004-07-15 | 2005-07-11 | microrganismo transformado selecionado a partir da espécie escherichia coli (e.coli) e processo para síntese bioquímica de 1,4-butanodiamina a partir do referido microrganismo |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8497098B2 (pt) |
| EP (2) | EP2949755B1 (pt) |
| JP (1) | JP4836948B2 (pt) |
| CN (1) | CN101010433B (pt) |
| AU (1) | AU2005261861B2 (pt) |
| BR (1) | BRPI0513343B1 (pt) |
| CA (1) | CA2571528C (pt) |
| DK (1) | DK1784496T3 (pt) |
| EA (1) | EA010179B1 (pt) |
| ES (1) | ES2581244T3 (pt) |
| IN (1) | IN2007DE00479A (pt) |
| MX (1) | MX2007000566A (pt) |
| MY (1) | MY152156A (pt) |
| NZ (1) | NZ552631A (pt) |
| TW (1) | TWI346139B (pt) |
| UA (1) | UA90479C2 (pt) |
| WO (1) | WO2006005603A1 (pt) |
| ZA (1) | ZA200700104B (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0714842A2 (pt) | 2006-08-01 | 2013-05-21 | Basf Se | processo para preparar um composto, composto, e, uso do composto |
| CN101063144B (zh) * | 2007-05-10 | 2010-09-15 | 南京农业大学 | 乳酸菌谷氨酸脱羧酶基因的克隆、表达及应用 |
| CA2718258C (en) | 2008-03-12 | 2016-12-13 | Toray Industries, Inc. | Method for producing diamine and polyamide |
| MY175283A (en) * | 2008-04-10 | 2020-06-18 | Korea Advanced Inst Sci & Tech | Mutant microorganisms having high ability to produce putrescine and method for producing putrescine using the same |
| FR2933414B1 (fr) * | 2008-07-07 | 2010-08-13 | Arkema France | Polyamide, composition comprenant un tel polyamide et leurs utilisations |
| JP5776907B2 (ja) * | 2009-07-24 | 2015-09-09 | ディーエスエム アイピー アセッツ ビー．ブイ． | Ｎ−アシル保護またはｎ−グアニジル保護１，４−ブタンジアミン前駆体を介する１，４−ブタンジアミンの調製方法 |
| KR20120083908A (ko) * | 2009-10-13 | 2012-07-26 | 게노마티카 인코포레이티드 | 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-ｃｏａ, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법 |
| KR101174267B1 (ko) * | 2010-01-06 | 2012-08-14 | 씨제이제일제당 (주) | Ｌ-오르니틴 또는 ｌ-아르기닌 생산 변이주 및 이의 제조방법 |
| KR101348461B1 (ko) * | 2010-12-08 | 2014-01-08 | 씨제이제일제당 (주) | 퓨트레신을 생산하는 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법 |
| KR101286158B1 (ko) * | 2011-08-24 | 2013-07-15 | 씨제이제일제당 (주) | 발효액에서 1,4-디아미노부탄의 분리 및 정제하는 방법 |
| AU2013208344B2 (en) * | 2012-01-11 | 2016-06-30 | Cj Cheiljedang Corporation | Recombinant Microorganisms With An Improved Productivity Of Putrescine And Method For Producing Putrescine Using The Same |
| PL2806022T3 (pl) * | 2012-01-20 | 2018-12-31 | Cj Cheiljedang Corporation | Rekombinowany mikroorganizm z poprawioną zdolnością do wytwarzania putrescyny oraz sposób wytwarzania putrescyny z jego zastosowaniem |
| KR20140052189A (ko) * | 2012-10-22 | 2014-05-07 | 씨제이제일제당 (주) | 1,4-디아미노부탄의 정제방법, 상기 방법으로 정제된 1,4-디아미노부탄 및 이로부터 제조되는 폴리아미드 |
| KR101607741B1 (ko) * | 2013-03-20 | 2016-03-31 | 씨제이제일제당 (주) | 퓨트레신 생산 재조합 미생물 및 이를 이용한 퓨트레신 생산방법 |
| KR101835164B1 (ko) * | 2013-07-17 | 2018-03-06 | 씨제이제일제당 (주) | 향상된 퓨트레신 생산능을 가지는 변이된 오르니틴 디카복실레이즈 단백질 및 이의 용도 |
| CN103951504A (zh) * | 2014-04-21 | 2014-07-30 | 扬州市嘉康菇业发展有限公司 | 一种促进金针菇菌丝体快速生长的培养基的制备方法 |
| JP6526791B2 (ja) | 2014-04-25 | 2019-06-05 | シージェイ チェイルジェダン コーポレーション | ジアミンを生産する微生物及びそれらを用いてジアミンを生産する方法 |
| AU2015250431B2 (en) | 2014-04-25 | 2017-09-28 | Cj Cheiljedang Corporation | Microorganisms for Producing Putrescine and Process for Producing Putrescine Using Them |
| EP3135757B1 (en) | 2014-04-25 | 2019-02-20 | CJ Cheiljedang Corporation | Diamine-producing microorganism and method for producing diamine using same |
| JP2017158434A (ja) * | 2014-07-22 | 2017-09-14 | 協同乳業株式会社 | バクテリア混合培養によるプトレッシン製造方法 |
| KR101813759B1 (ko) | 2015-06-24 | 2018-01-02 | 씨제이제일제당 (주) | 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법 |
| KR101735935B1 (ko) | 2015-07-20 | 2017-05-16 | 씨제이제일제당 (주) | 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법 |
| KR102011394B1 (ko) | 2017-07-19 | 2019-10-22 | 씨제이제일제당 주식회사 | 퓨트레신을 생산하는 미생물 및 이를 이용한 퓨트레신 생산방법 |
| EP3808848A1 (en) | 2019-10-14 | 2021-04-21 | Eberhard Karls Universität Tübingen | Regulatory element of an arginine decarboxylase gene and methods and uses thereof |
| KR102246288B1 (ko) | 2020-08-13 | 2021-04-29 | 씨제이제일제당 주식회사 | 퓨트레신 생산 미생물 및 이를 이용한 퓨트레신 생산방법 |
| CN113061562B (zh) * | 2021-03-22 | 2022-09-27 | 江南大学 | 一种利用钝齿棒杆菌发酵生产1,4-丁二胺的方法 |
| CN117736951B (zh) * | 2023-11-27 | 2026-03-03 | 天津科技大学 | 生产1,4-丁二胺的大肠杆菌底盘菌株及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2130948A (en) | 1937-04-09 | 1938-09-20 | Du Pont | Synthetic fiber |
| ES2088826B1 (es) | 1995-02-10 | 1997-06-01 | Taguidell Sociedad Limitada | Procedimiento de obtencion de las diaminas putrescina y cadaverina a partir de productos naturales tratados, su uso como aditivo en abonos, y abono correspondiente. |
| AU6464100A (en) | 1999-08-10 | 2001-03-05 | John Innes Centre | Polyamine accumulation in plants |
| JP2002345496A (ja) | 2001-05-25 | 2002-12-03 | Ajinomoto Co Inc | アグマチンの製造方法およびアルギニン脱炭酸酵素の製造方法 |
-
2005
- 2005-07-11 CN CN2005800236901A patent/CN101010433B/zh not_active Expired - Fee Related
- 2005-07-11 CA CA2571528A patent/CA2571528C/en not_active Expired - Fee Related
- 2005-07-11 AU AU2005261861A patent/AU2005261861B2/en not_active Ceased
- 2005-07-11 EP EP15175520.4A patent/EP2949755B1/en not_active Expired - Lifetime
- 2005-07-11 EA EA200700329A patent/EA010179B1/ru not_active IP Right Cessation
- 2005-07-11 BR BRPI0513343-2A patent/BRPI0513343B1/pt not_active IP Right Cessation
- 2005-07-11 NZ NZ552631A patent/NZ552631A/en not_active IP Right Cessation
- 2005-07-11 MX MX2007000566A patent/MX2007000566A/es active IP Right Grant
- 2005-07-11 DK DK05767851.8T patent/DK1784496T3/en active
- 2005-07-11 ES ES05767851.8T patent/ES2581244T3/es not_active Expired - Lifetime
- 2005-07-11 US US11/632,458 patent/US8497098B2/en not_active Expired - Fee Related
- 2005-07-11 UA UAA200701584A patent/UA90479C2/ru unknown
- 2005-07-11 WO PCT/EP2005/007606 patent/WO2006005603A1/en not_active Ceased
- 2005-07-11 JP JP2007520744A patent/JP4836948B2/ja not_active Expired - Fee Related
- 2005-07-11 EP EP05767851.8A patent/EP1784496B1/en not_active Expired - Lifetime
- 2005-07-15 TW TW094124157A patent/TWI346139B/zh not_active IP Right Cessation
- 2005-07-15 MY MYPI20053244 patent/MY152156A/en unknown
-
2007
- 2007-01-03 ZA ZA200700104A patent/ZA200700104B/en unknown
- 2007-01-17 IN IN479DE2007 patent/IN2007DE00479A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2571528A1 (en) | 2006-01-19 |
| ES2581244T3 (es) | 2016-09-02 |
| AU2005261861B2 (en) | 2010-08-26 |
| UA90479C2 (en) | 2010-05-11 |
| AU2005261861A1 (en) | 2006-01-19 |
| TWI346139B (en) | 2011-08-01 |
| EA010179B1 (ru) | 2008-06-30 |
| CN101010433A (zh) | 2007-08-01 |
| NZ552631A (en) | 2009-09-25 |
| EP2949755A1 (en) | 2015-12-02 |
| EP1784496B1 (en) | 2016-04-06 |
| EP1784496A1 (en) | 2007-05-16 |
| TW200605869A (en) | 2006-02-16 |
| CN101010433B (zh) | 2012-03-07 |
| ZA200700104B (en) | 2008-05-28 |
| JP2008505651A (ja) | 2008-02-28 |
| WO2006005603A1 (en) | 2006-01-19 |
| MY152156A (en) | 2014-08-15 |
| US8497098B2 (en) | 2013-07-30 |
| EA200700329A1 (ru) | 2007-08-31 |
| IN2007DE00479A (pt) | 2007-08-17 |
| JP4836948B2 (ja) | 2011-12-14 |
| MX2007000566A (es) | 2007-04-02 |
| CA2571528C (en) | 2016-02-16 |
| EP2949755B1 (en) | 2018-03-28 |
| US20090011478A1 (en) | 2009-01-08 |
| DK1784496T3 (en) | 2016-07-25 |
| BRPI0513343B1 (pt) | 2020-11-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O C/C 13, 10, 24 E 25 DA LPI. |
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| B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/11/2020, OBSERVADAS AS CONDICOES LEGAIS. |
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| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 20A ANUIDADE. |
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| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2840 DE 10-06-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |