BRPI0513437A - célula hospedeira eucariótica com a capacidade para isomerizar diretamente xilose em xilulose, e, processos para produzir etanol e um produto de fermentação - Google Patents

célula hospedeira eucariótica com a capacidade para isomerizar diretamente xilose em xilulose, e, processos para produzir etanol e um produto de fermentação

Info

Publication number
BRPI0513437A
BRPI0513437A BRPI0513437-4A BRPI0513437A BRPI0513437A BR PI0513437 A BRPI0513437 A BR PI0513437A BR PI0513437 A BRPI0513437 A BR PI0513437A BR PI0513437 A BRPI0513437 A BR PI0513437A
Authority
BR
Brazil
Prior art keywords
xylose
ability
processes
host cell
xylulose
Prior art date
Application number
BRPI0513437-4A
Other languages
English (en)
Inventor
Aaron Adriaan Winkler
Sipko Maarten Kuyper
Wilhelmus Theodorus Anton Laat
Johannes Pieter Van Dijken
Jacobus Thomas Pronk
Original Assignee
Univ Delft Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Delft Tech filed Critical Univ Delft Tech
Publication of BRPI0513437A publication Critical patent/BRPI0513437A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

CéLULA HOSPEDEIRA EUCARIóTICA COM A CAPACIDADE PARA ISOMERIZAR DIRETAMENTE XILOSE EM XILULOSE, E, PROCESSOS PARA PRODUZIR ETANOL E UM PRODUTO DE FERMENTAçãO A presente invenção diz respeito a modificações genéticas adicionais em células hospedeiras eucarióticas que foram transformadas para expressar uma xilose isomerase que confere à célula hospedeira a capacidade de isomerizar xilose para xilulose. As modificações genéticas adicionais são intencionadas a melhorar a eficiência do metabolismo de xilose e incluem por exemplo, a redução da atividade da aldose redutase não específica, atividade da xilulose quinase aumentada e fluxo aumentada do caminho da pentose fosfato. As células hospedeiras modificadas da invenção são adequadas para a produção de uma ampla variedade de produtos de fermentação, incluindo etanol, em processos de fermentação em que uma fonte de xilose ou uma fonte de xilose e glicose são usadas como fonte de carbono.
BRPI0513437-4A 2004-07-16 2005-07-15 célula hospedeira eucariótica com a capacidade para isomerizar diretamente xilose em xilulose, e, processos para produzir etanol e um produto de fermentação BRPI0513437A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US58838104P 2004-07-16 2004-07-16
EP04077073 2004-07-16
US58983304P 2004-07-22 2004-07-22
PCT/NL2005/000516 WO2006009434A1 (en) 2004-07-16 2005-07-15 Metabolic engineering of xylose fermenting eukaryotic cells

Publications (1)

Publication Number Publication Date
BRPI0513437A true BRPI0513437A (pt) 2008-05-06

Family

ID=34928378

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513437-4A BRPI0513437A (pt) 2004-07-16 2005-07-15 célula hospedeira eucariótica com a capacidade para isomerizar diretamente xilose em xilulose, e, processos para produzir etanol e um produto de fermentação

Country Status (10)

Country Link
US (3) US8034591B2 (pt)
EP (1) EP1781772B1 (pt)
JP (2) JP5796925B2 (pt)
CN (2) CN101914462B (pt)
BR (1) BRPI0513437A (pt)
CA (2) CA2573483C (pt)
DK (1) DK1781772T3 (pt)
ES (1) ES2607891T3 (pt)
PL (1) PL1781772T3 (pt)
WO (1) WO2006009434A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016065453A1 (pt) * 2014-10-30 2016-05-06 Biocelere Agroindustrial Ltda. Cassete de expressão para a transformação de célula eucariótica, processo para a transformação de célula eucariótica, micro-organismo geneticamente modificado, processo de produção de biocombustíveis e/ou bioquímicos e biocombustível e/ou bioquímico assim produzidos

Families Citing this family (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE418616T2 (de) 2002-01-23 2009-01-15 Royal Nedalco B V Fermentation von pentosezuckern
PL1781772T3 (pl) * 2004-07-16 2017-03-31 Dsm Ip Assets B.V. Metaboliczne modyfikowanie fermentujących ksylozę komórek eukariotycznych
EP1873246A1 (en) * 2006-06-26 2008-01-02 DSMIP Assets B.V. Biological process using a transaldolase
EP1873248A1 (en) * 2006-06-26 2008-01-02 DSMIP Assets B.V. Biological process using a glucose-6-phosphate isomerase
US20100086965A1 (en) * 2006-10-02 2010-04-08 Van Maris Antonius Jeroen Adriaan Metabolic engineering of arabinose-fermenting yeast cells
DK2069476T3 (en) * 2006-10-02 2016-11-28 Dsm Ip Assets Bv Metabolic MODIFICATION of arabinose-fermenting YEAST CELLS
WO2008144012A2 (en) * 2007-05-14 2008-11-27 The Regents Of The University Of California Xylose- and arabinose- metabolizing enzyme -encoding nucleotide sequences with refined translational kinetics and methods of making same
CA2693365A1 (en) * 2007-07-19 2009-01-22 Royal Nedalco B.V. Novel arabinose-fermenting eukaryotic cells
EP2062967A1 (en) 2007-11-21 2009-05-27 Technical University of Denmark Genetically engineered aspergillus
EP2250263A1 (en) * 2008-03-07 2010-11-17 DSM IP Assets B.V. A pentose sugar fermenting cell
JP5625199B2 (ja) * 2008-03-07 2014-11-19 ディーエスエム アイピー アセッツ ビー．ブイ． ペントース糖発酵細胞
WO2009109631A1 (en) * 2008-03-07 2009-09-11 Dsm Ip Assets B.V. A pentose sugar fermenting cell
WO2009109630A1 (en) * 2008-03-07 2009-09-11 Dsm Ip Assets B.V. A pentose sugar fermenting cell
GB0812318D0 (en) 2008-07-04 2008-08-13 Terranol As Microorganism
WO2010014817A2 (en) * 2008-07-30 2010-02-04 Novozymes A/S Producing fermentation products
NZ593469A (en) * 2008-11-21 2012-12-21 Mascoma Corp Yeast expressing cellulases for simultaneous saccharification and fermentation using cellulose
GB0822937D0 (en) 2008-12-16 2009-01-21 Terranol As Microorganism
CA2746818A1 (en) 2008-12-24 2010-07-01 C5 Yeast Company B.V. Xylose isomerase genes and their use in fermentation of pentose sugars
AU2010216616A1 (en) * 2009-02-23 2011-10-20 Kirin Holdings Kabushiki Kaisha Manufacturing method for substances from Candida utilis that can use xylose as carbon source
CN102498202A (zh) * 2009-02-25 2012-06-13 印第安纳大学研究和科技公司 鉴定和使用在d-葡萄糖存在下代谢戊糖的酵母菌株的材料和方法
WO2010147642A1 (en) 2009-06-15 2010-12-23 Massachusetts Institute Of Technology Production of triacylglycerides, fatty acids, and their derivatives
EP2451960A2 (en) * 2009-07-09 2012-05-16 Verdezyne, Inc. Engineered microorganisms with enhanced fermentation activity
UA108853C2 (uk) 2009-07-10 2015-06-25 Спосіб ферментації галактози
EP2277989A1 (en) 2009-07-24 2011-01-26 Technische Universiteit Delft Fermentative glycerol-free ethanol production
US20120282664A1 (en) * 2009-11-30 2012-11-08 Akihiko Kondo Process for production of ethanol from biomass
JP5843229B2 (ja) * 2009-12-22 2016-01-13 株式会社豊田中央研究所 キシロースイソメラーゼ及びその利用
JP2013524797A (ja) 2010-04-21 2013-06-20 ディーエスエム アイピー アセッツ ビー．ブイ． アラビノースを転化できる細胞を製造する方法
US9605269B2 (en) 2010-05-05 2017-03-28 Lallemand Hungary Liquidity Management Llc Detoxification of biomass derived acetate via metabolic conversion to ethanol, acetone, isopropanol, or ethyl acetate
WO2011149353A1 (en) 2010-05-27 2011-12-01 C5 Yeast Company B.V. Yeast strains engineered to produce ethanol from acetic acid and glycerol
CN103124783A (zh) 2010-06-03 2013-05-29 马斯科马公司 表达用于使用淀粉和纤维素进行联合生物加工的糖分解酶的酵母
US8679822B2 (en) * 2010-06-29 2014-03-25 E I Du Pont De Nemours And Company Xylose utilization in recombinant zymomonas
US10138504B2 (en) 2010-08-06 2018-11-27 Lallemand Hungary Liquidity Management Llc Production of malonyl-CoA derived products via anaerobic pathways
CN102399804A (zh) * 2010-09-15 2012-04-04 中国农业科学院作物科学研究所 木糖异构酶基因的功能及其应用
JP5961886B2 (ja) 2010-10-13 2016-08-03 ディーエスエム アイピー アセッツ ビー．ブイ． ペントースおよびグルコース発酵酵母細胞
DK2663645T3 (da) 2010-11-18 2015-03-23 Dsm Ip Assets Bv Gærstammer, der er modificeret til produktion af ethanol fra glycerol
JP2012120491A (ja) * 2010-12-09 2012-06-28 Toyota Motor Corp キシロースを含む培地における発酵培養方法
CN103429751A (zh) 2010-12-22 2013-12-04 马斯科马公司 经工程化以发酵木糖的遗传修饰的热纤梭菌
CN102174549B (zh) 2011-02-22 2012-10-10 山东大学 一种编码木糖异构酶的核酸分子及其编码的木糖异构酶
WO2012125027A1 (en) 2011-03-14 2012-09-20 Dsm Ip Assets B.V. Yeast strains that ferment uronic acids
EP2694662B1 (en) 2011-04-05 2020-01-08 Lallemand Hungary Liquidity Management LLC Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors
WO2012143513A2 (en) 2011-04-22 2012-10-26 Dsm Ip Assets B.V. Yeast cell capable of converting sugars including arabinose and xylose
EP2546336A1 (en) 2011-07-11 2013-01-16 DSM IP Assets B.V. Yeast strains that consume uronic acids and produce fermentation products such as ethanol
MX2014006446A (es) 2011-11-30 2014-09-01 Dsm Ip Assets Bv Cepas de levadura manipuladas para producir etanol a partir de acido acetico y glicerol.
MX355028B (es) 2012-01-23 2018-03-28 Dsm Ip Assets Bv Produccion de diterpeno.
AU2013230930B2 (en) * 2012-03-06 2018-10-11 Lygos, Inc. Recombinant host cells for the production of malonate
JP6249391B2 (ja) * 2012-06-15 2017-12-20 国立研究開発法人農業・食品産業技術総合研究機構 キシロースを高温で発酵する方法
IN2015DN01042A (pt) 2012-08-28 2015-06-26 Dsm Ip Assets Bv
WO2014033018A1 (en) 2012-08-28 2014-03-06 Dsm Ip Assets B.V. Yeast strains engineered to produce ethanol from acetate
WO2014035458A1 (en) 2012-08-29 2014-03-06 Mascoma Corporation Expression of enzymes in yeast for lignocellulose derived oligomer cbp
US10604773B2 (en) 2012-10-16 2020-03-31 Dsm Ip Assets B.V. Cells with improved pentose conversion
ES2717682T3 (es) 2012-10-16 2019-06-24 Dsm Ip Assets Bv Células con conversión mejorada de pentosas
IN2015DN03292A (pt) 2012-11-07 2015-10-09 Dsm Ip Assets Bv
CA2889890C (en) 2012-11-09 2023-03-28 Lallemand Hungary Liquidity Management Llc Method for acetate consumption during ethanolic fermentation of cellulosic feedstocks
WO2014160402A1 (en) 2013-03-14 2014-10-02 Mascoma Corporation Co-conversion of carbohydrates to fermentation products in a single fermentation step
WO2014142647A1 (en) 2013-03-14 2014-09-18 Wageningen Universiteit Fungals strains with improved citric acid and itaconic acid production
DE102013205986A1 (de) 2013-04-04 2014-10-23 Wacker Chemie Ag Mikroorganismenstamm und Verfahren zur fermentativen Herstellung von C4-Verbindungen aus C5-Zuckern
BR112015029580A2 (pt) 2013-05-31 2017-09-19 Dsm Ip Assets Bv Microrganismo recombinante, processo para a preparação de um diterpeno ou diterpeno glicosilado, diterpeno ou diterpeno glicosilado, gêneros alimentícios, alimentos para animais ou bebidas e método para converter um primeiro diterpeno glicosilado em um segundo diterpeno glicosilado
BR112016000745B1 (pt) 2013-07-15 2021-01-05 Dsm Ip Assets B.V. processo para a preparação de rebaudiosídeo m
DK3027632T3 (da) 2013-07-31 2019-06-17 Dsm Ip Assets Bv Indvinding af steviolglycosider fra et fermenteringsmedium
US11753656B2 (en) 2013-08-15 2023-09-12 Lallemand Hungary Liquidity Management Llc Methods for the improvement of product yield and production in a microorganism through glycerol recycling
AR097480A1 (es) 2013-08-29 2016-03-16 Dsm Ip Assets Bv Células de levadura convertidoras de glicerol y ácido acético con una conversión de ácido acético mejorada
WO2015066642A1 (en) * 2013-11-04 2015-05-07 The Board Of Trustees Of The Leland Stanford Junior University Benzylisoquinoline alkaloid (bia) precursor producing microbes, and methods of making and using the same
US20180030482A1 (en) 2014-04-18 2018-02-01 Moralco B.V. Use of acetaldehyde in the fermentative production of ethanol
BR102014014407A2 (pt) * 2014-06-12 2016-04-19 Biocelere Agroindustrial Ltda cassete de expressão para transformar célula eucariótica, micro-organismo geneticamente modificado com eficiente consumo de xilose, processo para produção de biocombustíveis e bioquímicos e biocombustível e/ou bioquímico assim produzido
WO2016012429A1 (en) 2014-07-24 2016-01-28 Dsm Ip Assets B.V. Yeast cell with improved pentose transport
PL3250698T3 (pl) 2015-01-28 2020-06-29 Dsm Ip Assets B.V. Sposób enzymatycznej hydrolizy materiału lignocelulozowego i fermentacji cukrów
WO2016120298A1 (en) 2015-01-28 2016-08-04 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars
PL3640336T3 (pl) 2015-01-28 2022-08-01 Dsm Ip Assets B.V. Sposób enzymatycznej hydrolizy materiału lignocelulozowego i fermentacji cukrów
EP3271457B1 (en) 2015-03-16 2021-01-20 DSM IP Assets B.V. Udp-glycosyltransferases
US20180057850A1 (en) 2015-03-23 2018-03-01 Dsm Ip Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
CN107666834B (zh) 2015-04-03 2021-08-24 帝斯曼知识产权资产管理有限公司 甜菊醇糖苷
WO2016169893A1 (en) 2015-04-20 2016-10-27 Dsm Ip Assets B.V. Whole fermentation broth
WO2016169892A1 (en) 2015-04-20 2016-10-27 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars
CA2980649A1 (en) 2015-04-21 2016-10-27 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthase
WO2016207144A1 (en) 2015-06-22 2016-12-29 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars
CA2991651A1 (en) 2015-07-10 2017-01-19 Dsm Ip Assets B.V. Steviol glycoside composition
AU2016293487B2 (en) 2015-07-13 2021-07-01 MARA Renewables Corporation Enhancing microalgal metabolism of xylose
EP3332004B1 (en) 2015-08-05 2025-01-22 Cargill, Incorporated Xylose isomerase-modified yeast strains and methods for bioproduct production
US20180230505A1 (en) 2015-08-13 2018-08-16 Dsm Ip Assets B.V. Steviol glycoside transport
CN106554924B (zh) * 2015-09-24 2019-12-06 中粮营养健康研究院有限公司 生产乙醇的重组酿酒酵母菌株、其构建方法以及利用该菌株生产乙醇的方法
BR112018006724A2 (pt) 2015-10-05 2018-10-09 Dsm Ip Assets Bv ácido caurenoico hidroxilases
EP3371317A1 (en) * 2015-11-06 2018-09-12 Lallemand Hungary Liquidity Management LLC Limiting yeast-produced trehalose in fermentation
CN105838744A (zh) * 2016-04-26 2016-08-10 上海交通大学 制备2-表-5-表有效醇酮的方法
EP3469090A1 (en) 2016-06-09 2019-04-17 DSM IP Assets B.V. Seed train for large scale enzyme production
WO2018019948A1 (en) 2016-07-29 2018-02-01 Dsm Ip Assets B.V. Polypeptides having cellulolytic enhancing activity and uses thereof
EP3497110A1 (en) 2016-08-09 2019-06-19 DSM IP Assets B.V. Crystallization of steviol glycosides
MY202890A (en) 2016-08-09 2024-05-28 Dsm Ip Assets Bv Crystallization of steviol glycosides
CN109890961B (zh) 2016-10-27 2024-03-08 帝斯曼知识产权资产管理有限公司 香叶基香叶基焦磷酸酯合酶
CA3040380A1 (en) 2016-11-04 2018-05-11 Inbicon A/S Method for preparing fermentable sugars from lignocellulosic biomass
US11499142B2 (en) 2016-11-24 2022-11-15 Dsm Ip Assets B.V. Enzyme composition
CA3043435A1 (en) 2016-11-24 2018-05-31 Dsm Ip Assets B.V. Enzyme compositions with improved hydrolysis performance
CA3045722A1 (en) 2016-12-08 2018-06-14 Dsm Ip Assets B.V. Kaurenoic acid hydroxylases
WO2018115251A1 (en) 2016-12-21 2018-06-28 Vib Vzw Xylose isomerases that confer efficient xylose fermentation capability to yeast
WO2018114995A1 (en) 2016-12-22 2018-06-28 Dsm Ip Assets B.V. Fermentation process for producing steviol glycosides
CA3047889A1 (en) * 2016-12-22 2018-06-28 Lallemand Hungary Liquidity Management Llc Sulfite tolerance in recombinant yeast host cells
WO2018185071A1 (en) 2017-04-03 2018-10-11 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars
EP3645714B1 (en) 2017-06-27 2022-08-31 DSM IP Assets B.V. Udp-glycosyltransferases
EP3676288A1 (en) * 2017-08-29 2020-07-08 Danisco US Inc. Modified yeast comprising glucose-specific, atp-mediated transporters
FI3695001T3 (fi) 2017-10-09 2024-02-14 Versalis Spa Menetelmä lignoselluloosamateriaalin entsymaattista hydrolyysiä ja sokerien fermentointia varten
WO2019086370A1 (en) 2017-10-30 2019-05-09 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars
WO2019086369A1 (en) 2017-10-30 2019-05-09 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material and fermentation of sugars
BR112020018791A2 (pt) 2018-03-28 2020-10-13 Dsm Ip Assets B.V. composição de enzima
WO2019185681A1 (en) 2018-03-28 2019-10-03 Dsm Ip Assets B.V. Enzyme composition
EP3788059B1 (en) 2018-04-30 2025-08-13 DSM IP Assets B.V. Steviol glycoside transport
BR112020023198A2 (pt) 2018-05-17 2021-02-09 Dsm Ip Assets B.V. processo para produção de um polipeptídeo
JP7460540B2 (ja) 2018-05-22 2024-04-02 ディーエスエム アイピー アセッツ ビー．ブイ． 修飾ステロールアシルトランスフェラーゼ
EP3802843B1 (en) 2018-05-30 2023-03-29 Versalis S.p.A. Process for producing sugars from carbohydrate materials
WO2020058253A1 (en) 2018-09-18 2020-03-26 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of carbohydrate material and fermentation of sugars
WO2020058248A1 (en) 2018-09-18 2020-03-26 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of carbohydrate material and fermentation of sugars
WO2020058249A1 (en) 2018-09-18 2020-03-26 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of carbohydrate material and fermentation of sugars
AU2019365525B2 (en) * 2018-10-23 2025-10-30 MARA Renewables Corporation Adaptation and process optimization of microorganisms for growth in hemicellulosic derived carbohydrates
CN109593662B (zh) * 2018-12-11 2021-12-03 大连理工大学 一种乙酸和木糖共利用的马克斯克鲁维酵母菌株及筛选方法
CN109504695B (zh) * 2019-01-02 2022-08-09 中国农业科学院作物科学研究所 多中心单鞭毛菌木糖异构酶基因及其应用
CN113544280A (zh) 2019-03-12 2021-10-22 帝斯曼知识产权资产管理有限公司 用于产生发酵液的方法
CN114391041A (zh) 2019-09-10 2022-04-22 帝斯曼知识产权资产管理有限公司 酶组合物
WO2021089877A1 (en) 2019-11-08 2021-05-14 Dsm Ip Assets B.V. Process for producing ethanol
US20250290081A1 (en) 2020-10-22 2025-09-18 Dsm Ip Assets B.V. Microorganisms for diterpene production
CN117178059A (zh) 2021-04-06 2023-12-05 帝斯曼知识产权资产管理有限公司 酶组合物
WO2022214459A1 (en) 2021-04-06 2022-10-13 Dsm Ip Assets B.V. Enzyme composition
BR112023020370A2 (pt) 2021-04-06 2023-11-21 Dsm Ip Assets Bv Composição de enzimas
CA3197143A1 (en) 2021-04-08 2022-10-13 Versalis S.P.A. Process for the preparation of a sugar product and a fermentation product
CN115851850B (zh) * 2021-09-23 2025-11-28 中国科学院天津工业生物技术研究所 利用二氧化碳制备淀粉的方法、重组微生物和构建重组微生物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10117771A (ja) * 1996-10-23 1998-05-12 Natl Food Res Inst 冷凍生地耐性実用パン酵母
US6566107B1 (en) * 2000-11-01 2003-05-20 Midwest Research Institute Recombinant Zymomonas mobilis with improved xylose utilization
ATE418616T2 (de) * 2002-01-23 2009-01-15 Royal Nedalco B V Fermentation von pentosezuckern
JP4711955B2 (ja) * 2003-05-02 2011-06-29 ネイチャーワークス・エル・エル・シー 遺伝子組換え酵母及び遺伝子組換え酵母を用いた発酵方法
PL1781772T3 (pl) * 2004-07-16 2017-03-31 Dsm Ip Assets B.V. Metaboliczne modyfikowanie fermentujących ksylozę komórek eukariotycznych

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016065453A1 (pt) * 2014-10-30 2016-05-06 Biocelere Agroindustrial Ltda. Cassete de expressão para a transformação de célula eucariótica, processo para a transformação de célula eucariótica, micro-organismo geneticamente modificado, processo de produção de biocombustíveis e/ou bioquímicos e biocombustível e/ou bioquímico assim produzidos

Also Published As

Publication number Publication date
EP1781772B1 (en) 2016-09-28
US20120225451A1 (en) 2012-09-06
CN101052706A (zh) 2007-10-10
WO2006009434A1 (en) 2006-01-26
ES2607891T3 (es) 2017-04-04
US8790903B2 (en) 2014-07-29
CN101914462A (zh) 2010-12-15
CA2573483A1 (en) 2006-01-26
CA2861834A1 (en) 2006-01-26
JP5796925B2 (ja) 2015-10-21
EP1781772A1 (en) 2007-05-09
DK1781772T3 (en) 2017-01-09
PL1781772T3 (pl) 2017-03-31
US8034591B2 (en) 2011-10-11
JP2008506383A (ja) 2008-03-06
US20080261287A1 (en) 2008-10-23
CA2573483C (en) 2014-10-28
US20150010943A1 (en) 2015-01-08
CN101914462B (zh) 2013-04-24
JP2013055948A (ja) 2013-03-28
CN101052706B (zh) 2015-02-18

Similar Documents

Publication Publication Date Title
Burke et al. An engineered cytidine deaminase for biocatalytic production of a key intermediate of the Covid-19 antiviral molnupiravir
Ellis et al. Acetone, butanol, and ethanol production from wastewater algae
BRPI0513837A (pt) células hospedeiras geneticamente modificadas e uso das mesmas para produzir compostos isoprenóides
BRPI0409954A (pt) espécies leveduras geneticamente modificados e processos de fermentação utilizando levedura geneticamente modificada
BRPI0611535A8 (pt) Métodos para processar células de microorganismos e células de levedura, composição, suplemento alimentar, produto farmacêutico, cosmético ou produto nutracêutico e ração animal
BR112014012963B8 (pt) Processo para a produção de etanol e célula de levedura
BR0306740A (pt) Célula hospedeira transformada com um construto de ácido nucléico, molécula de ácido nucleico isolada, e, processos para a produção de etanol, e de um produto de fermentação
BR0309796A (pt) Linhagens de zymomonas de fermentação de açúcar pentose e usos das mesmas, processo, método, integrante de zymomonas e biocatalisador
BR112023008361A2 (pt) Variantes de glucoamilase e polinucleotídeos codificando as mesmas
Piwowarek et al. Use of apple pomace, glycerine, and potato wastewater for the production of propionic acid and vitamin B12
Sedlak et al. DNA microarray analysis of the expression of the genes encoding the major enzymes in ethanol production during glucose and xylose co-fermentation by metabolically engineered Saccharomyces yeast
Huang et al. A thermostable recombinant transaldolase with high activity over a broad pH range
Lin et al. An effective strategy for the co-production of S-adenosyl-L-methionine and glutathione by fed-batch fermentation
WO2023001294A9 (zh) 一种重组酵母生物转化生产葡萄糖及其衍生物的方法
Yen et al. The effects of dissolved oxygen level on the distribution of 1, 3-propanediol and 2, 3-butanediol produced from glycerol by an isolated indigenous Klebsiella sp. Ana-WS5
Yang et al. Collagen peptide protects Saccharomyces cerevisiae from furfural stress for enhancing bioethanol synthesis
BR112014019578A8 (pt) Células de saccharomyces cerevisiae, usos das ditas células e molécula de dna e processos para a produção de etanol e de produto de fermentação
Wang et al. Shaping up a Mevalonate Pathway in the E. coli–E. coli Coculture System for the Production of Sesquiterpenes
PT2069515E (pt) Processo para a produção de eritrol com utilização de estirpes de moniliella tomentosa na presença de nitratos inorgânicos neutros tais como nitrato de potássio, nitrato de amónio ou nitrato de sódio como fonte de nitrogénio
Jiang et al. Cell-free synthetic biology in the new era of enzyme engineering
Tang et al. Improving Biosynthesis Efficiency of Nicotinamide Mononucleotide by ATP Recycling Engineering and Condition Optimization
BR112023003329A2 (pt) Produção fermentativa anaeróbia de furandimetanol e produção enzimática de ácido furandicarboxílico
Cao et al. A Series of Efficient Umbrella Modeling Strategies to Track Irradiation-Mutation Strains Improving Butyric Acid Production From the Pre-development Earlier Stage Point of View
Pengfei et al. Efficient whole-cell biosynthesis of S-adenosyl-L-methionine by the engineered Escherichia coli with high ATP regenerating system
Beenstock et al. A suite of in vitro and in vivo assays for monitoring the activity of the pseudokinase Bud32

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: DSM IP ASSETS B.V (NL)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 24 E 25 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]