BRPI0513897A - diferenciação de células-tronco - Google Patents

diferenciação de células-tronco

Info

Publication number
BRPI0513897A
BRPI0513897A BRPI0513897-3A BRPI0513897A BRPI0513897A BR PI0513897 A BRPI0513897 A BR PI0513897A BR PI0513897 A BRPI0513897 A BR PI0513897A BR PI0513897 A BRPI0513897 A BR PI0513897A
Authority
BR
Brazil
Prior art keywords
stem cell
cell differentiation
compositions
disclosure
methods
Prior art date
Application number
BRPI0513897-3A
Other languages
English (en)
Inventor
James H Kelly
Original Assignee
Stem Cell Innovations Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stem Cell Innovations Inc filed Critical Stem Cell Innovations Inc
Publication of BRPI0513897A publication Critical patent/BRPI0513897A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/44—Thiols, e.g. mercaptoethanol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

DIFERENCIAçãO DE CéLULAS-TRONCO. A presente invenção se refere à divulgação de composições e métodos para a identificação de tipos específicos de células.
BRPI0513897-3A 2004-07-29 2005-07-29 diferenciação de células-tronco BRPI0513897A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59202704P 2004-07-29 2004-07-29
PCT/US2005/026976 WO2006015209A2 (en) 2004-07-29 2005-07-29 Differentiation of stem cells

Publications (1)

Publication Number Publication Date
BRPI0513897A true BRPI0513897A (pt) 2008-05-20

Family

ID=35058317

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513897-3A BRPI0513897A (pt) 2004-07-29 2005-07-29 diferenciação de células-tronco

Country Status (9)

Country Link
US (1) US20060068496A1 (pt)
EP (1) EP1781776A2 (pt)
JP (1) JP2008507981A (pt)
KR (1) KR20070058453A (pt)
CN (1) CN101031640A (pt)
AU (1) AU2005267841A1 (pt)
BR (1) BRPI0513897A (pt)
CA (1) CA2575614A1 (pt)
WO (1) WO2006015209A2 (pt)

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US8053627B2 (en) * 2005-06-14 2011-11-08 University Of Chicago Methods for treating demyelination disorders
US7884260B2 (en) * 2005-06-14 2011-02-08 University Of Chicago Cell-based screen for agents useful for reducing neuronal demyelination or promoting neuronal remyelination
US7423194B2 (en) * 2005-06-14 2008-09-09 University Of Chicago Animal models for demyelination disorders
US20080064098A1 (en) * 2006-06-05 2008-03-13 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of maternal placental cells
US20080050814A1 (en) * 2006-06-05 2008-02-28 Cryo-Cell International, Inc. Procurement, isolation and cryopreservation of fetal placental cells
WO2008024832A2 (en) * 2006-08-24 2008-02-28 Cedars-Sinai Medical Center Methods for isolating and using pituitary adenoma stem cells and pituitary adenoma cells
US20100062477A1 (en) * 2006-11-28 2010-03-11 Cedars-Sinai Medical Center Methods of isolating and propagating stem cells from benign tumors
US20090148535A1 (en) * 2007-12-06 2009-06-11 Minerva Biotechnologies Corporation Method for treating cancer using interference rna
AU2009205886B2 (en) * 2008-01-18 2015-08-27 Katholieke Universiteit Leuven Stem cell aggregates and methods for making and using
WO2010036923A1 (en) * 2008-09-25 2010-04-01 Salk Institute For Biological Studies Induced pluripotent stem cells and methods of use
WO2010138750A2 (en) * 2009-05-27 2010-12-02 The Salk Institute For Biological Studies Generation of genetically corrected disease-free induced pluripotent stem cells
WO2011051450A1 (en) * 2009-10-29 2011-05-05 Vib Vzw Cardiac-specific nucleic acid regulatory elements and methods and use thereof
EP2609191B1 (en) 2010-08-24 2017-11-22 Regents Of The University Of Minnesota Non-static suspension culture of cell aggregates
CA2858173C (en) * 2011-12-06 2023-09-26 Advanced Cell Technology, Inc. Method of directed differentiation producing corneal endothelial cells, compositions thereof, and uses thereof
US10724005B2 (en) * 2012-09-28 2020-07-28 Scripps Health Methods of differentiating stem cells into chondrocytes
EP2912166B1 (en) 2012-10-29 2019-05-01 Scripps Health Methods of producing pluripotent stem cells from chondrocytes
JP6324395B2 (ja) 2012-10-29 2018-05-16 スクリップス ヘルス 軟骨細胞を移植する方法
US10745761B2 (en) 2014-06-02 2020-08-18 Valley Health System Method and systems for lung cancer diagnosis
SG11201705401YA (en) * 2014-12-30 2017-08-30 The Brigham And Women`S Hospital Inc Methods to improve cell therapy
DK3347456T3 (da) * 2015-09-08 2024-02-19 Us Health Fremgangsmåde til reproducerbar differentiering af retinale pigmentepitelceller af klinisk kvalitet
SE540173C2 (en) * 2016-04-20 2018-04-24 Hiloprobe Ab Marker genes for colorectal cancer classification, method for judging lymph node metastasis for prognosis of colorectal cancer and kit therefor
WO2018053306A1 (en) * 2016-09-15 2018-03-22 University Of Miami Double suicide gene vector systems for stem cells
TW201833803A (zh) * 2017-02-08 2018-09-16 美商歐瑞３恩公司 用於誘導多能幹細胞隔離和組合生產的系統、方法及設備
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
JP7414281B2 (ja) * 2017-08-08 2024-01-16 クイーンズランド ユニバーシティ オブ テクノロジー 初期心不全の診断方法
CN109022488A (zh) * 2018-07-25 2018-12-18 佛山科学技术学院 一种条件性细胞永生化慢病毒载体及其构建方法和在猪卵巢颗粒细胞建系中的应用
CN109851677B (zh) * 2019-02-26 2022-02-25 山东大学 一种特异性检测多硫化物的蛋白荧光探针及其制备方法与应用
PE20212082A1 (es) * 2019-04-24 2021-10-28 Univ Oregon Health & Science Secuencia promotora y productos y usos relacionados de la misma
CN110643571B (zh) * 2019-10-22 2021-07-27 康妍葆(北京)干细胞科技有限公司 人角蛋白6a在干细胞培养中的应用及产品
CN114846151A (zh) * 2020-01-17 2022-08-02 株式会社日立高新技术 细胞分化状态的评价方法以及细胞培养系统
EP4129311A4 (en) * 2020-03-31 2024-06-12 Keio University Therapeutic agent using genome-edited pluripotent stem cell
CN111944033B (zh) * 2020-08-06 2022-03-15 中国农业大学 Rbp4蛋白或其编码基因在调控成肌细胞分化和融合中的应用
CN113801852B (zh) * 2021-10-18 2023-08-18 齐齐哈尔医学院 一种gpd1l缺失人胚胎干细胞细胞株及其构建方法和应用
CN114752626A (zh) * 2022-03-16 2022-07-15 重庆医科大学附属儿童医院 一种可逆性永生化ⅱ型肺泡上皮细胞及其构建与应用
CN116287090A (zh) * 2023-02-10 2023-06-23 同济大学 一种检测细胞naïve态多能性的方法及可指征naïve态多能性的双报告系统

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CA2081782C (en) * 1990-05-16 2004-08-24 James H. Kelly Permanent human hepatocyte cell line and its use in a liver assist device (lad)
US5849553A (en) * 1992-07-27 1998-12-15 California Institute Of Technology Mammalian multipotent neural stem cells
US5672499A (en) * 1992-07-27 1997-09-30 California Institute Of Technology Immoralized neural crest stem cells and methods of making
US5453357A (en) * 1992-10-08 1995-09-26 Vanderbilt University Pluripotential embryonic stem cells and methods of making same
US5690926A (en) * 1992-10-08 1997-11-25 Vanderbilt University Pluripotential embryonic cells and methods of making same
US5368555A (en) * 1992-12-29 1994-11-29 Hepatix, Inc. Organ support system
GB9308271D0 (en) * 1993-04-21 1993-06-02 Univ Edinburgh Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method
US5811281A (en) * 1993-07-12 1998-09-22 Cornell Research Foundation, Inc. Immortalized intestinal epithelial cell lines
WO1996014400A1 (en) * 1994-11-08 1996-05-17 Bradley Michael John Stringer Human cell-lines
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US6534314B1 (en) * 1996-06-14 2003-03-18 Massachusetts Institute Of Technology Methods and compositions for transforming cells
US6090622A (en) * 1997-03-31 2000-07-18 The Johns Hopkins School Of Medicine Human embryonic pluripotent germ cells
GB0300208D0 (en) * 2003-01-06 2003-02-05 Oxford Biomedica Ltd Insulin producing cells

Also Published As

Publication number Publication date
AU2005267841A1 (en) 2006-02-09
CN101031640A (zh) 2007-09-05
JP2008507981A (ja) 2008-03-21
KR20070058453A (ko) 2007-06-08
CA2575614A1 (en) 2006-02-09
WO2006015209A2 (en) 2006-02-09
US20060068496A1 (en) 2006-03-30
EP1781776A2 (en) 2007-05-09
WO2006015209A3 (en) 2006-06-08

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.

B15K Others concerning applications: alteration of classification

Ipc: C12N 5/0735 (2010.01)