BRPI0514005A - composto, composição farmacêutica, uso de um composto, método para o tratamento ou prevenção de distúrbios neurológicos e psiquiátricos associados com a disfunção de glutamato em um animal, e, processo para a preparação de um composto - Google Patents

composto, composição farmacêutica, uso de um composto, método para o tratamento ou prevenção de distúrbios neurológicos e psiquiátricos associados com a disfunção de glutamato em um animal, e, processo para a preparação de um composto

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Publication number
BRPI0514005A
BRPI0514005A BRPI0514005-6A BRPI0514005A BRPI0514005A BR PI0514005 A BRPI0514005 A BR PI0514005A BR PI0514005 A BRPI0514005 A BR PI0514005A BR PI0514005 A BRPI0514005 A BR PI0514005A
Authority
BR
Brazil
Prior art keywords
compound
psychiatric disorders
animal
pharmaceutical composition
disorders associated
Prior art date
Application number
BRPI0514005-6A
Other languages
English (en)
Inventor
Joshua Clayton
Fupeng Ma
Bradford Van Wagenen
Radhakrishnan Ukkiramapandian
Ian Egle
James Empfield
Methvin Isaac
Abdelmalik Slassi
Gary Steelman
Rebecca Urbanek
Sally Walsh
Original Assignee
Astrazeneca Ab
Nps Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35428151&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0514005(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab, Nps Pharma Inc filed Critical Astrazeneca Ab
Publication of BRPI0514005A publication Critical patent/BRPI0514005A/pt

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Abstract

COMPOSTO, COMPOSIçãO FARMACêUTICA, USO DE UM COMPOSTO, MéTODO PARA O TRATAMENTO OU PREVENçãO DE DISTúRBIOS NEUROLóGICOS E PSIQUIáTRICOS ASSOCIADOS COM A DISFUNçãO DE GLUTAMATO EM UM ANIMAL, E, PROCESSO PARA A PREPARAçãO DE UM COMPOSTO A presente invenção está direcionada aos compostos da Fórmula (I) em que R¬ ¬ é um anel e n é um número de 1 a 8. A invenção também diz respeito ao uso dos compostos em terapia como moduladores do receptor de glutamato metabotrópicos, particularmente em distúrbios neurológicos e psiquiátricos.
BRPI0514005-6A 2004-08-13 2005-08-12 composto, composição farmacêutica, uso de um composto, método para o tratamento ou prevenção de distúrbios neurológicos e psiquiátricos associados com a disfunção de glutamato em um animal, e, processo para a preparação de um composto BRPI0514005A (pt)

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PCT/US2005/028760 WO2006020879A1 (en) 2004-08-13 2005-08-12 Isoindolone compounds and their use as metabotropic glutamate receptor potentiators

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