BRPI0514407A - forma ii de polimorfo de rapamicina, processos para preparar a forma ii do polimorfo de rapaminicina, e a forma i do polimorfo de rapamicina, composição farmacêutica, kit, e, método para preparar uma composição farmacêutica - Google Patents

forma ii de polimorfo de rapamicina, processos para preparar a forma ii do polimorfo de rapaminicina, e a forma i do polimorfo de rapamicina, composição farmacêutica, kit, e, método para preparar uma composição farmacêutica

Info

Publication number
BRPI0514407A
BRPI0514407A BRPI0514407-8A BRPI0514407A BRPI0514407A BR PI0514407 A BRPI0514407 A BR PI0514407A BR PI0514407 A BRPI0514407 A BR PI0514407A BR PI0514407 A BRPI0514407 A BR PI0514407A
Authority
BR
Brazil
Prior art keywords
polymorph form
pharmaceutical composition
preparing
rapamycin polymorph
rapamycin
Prior art date
Application number
BRPI0514407-8A
Other languages
English (en)
Inventor
Tianmin Zhu
Mahdi B Fawzi
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35431373&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0514407(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BRPI0514407A publication Critical patent/BRPI0514407A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

FORMA II DE POLIMORFO DE RAPAMICINA, PROCESSOS PARA PREPARAR A FORMA II DO POLIMORFO DE RAPAMICINA, E A FORMA I DO POLIMORFO DE RAPAMICINA, COMPOSIçãO FARMACêUTICA, KIT, E, MéTODO PARA PREPARAR UMA COMPOSIçãO FARMACêUTICA A presente invenção provê a Forma II do polimorfo de rapamicina. Esta invenção refere-se também a processos para a preparação da Forma II do polimorfo de rapamicina e a composições farmacêuticas, que incluem a Forma H do polimorfo de rapamicina.
BRPI0514407-8A 2004-08-20 2005-08-18 forma ii de polimorfo de rapamicina, processos para preparar a forma ii do polimorfo de rapaminicina, e a forma i do polimorfo de rapamicina, composição farmacêutica, kit, e, método para preparar uma composição farmacêutica BRPI0514407A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60309604P 2004-08-20 2004-08-20
PCT/US2005/029364 WO2006023627A1 (en) 2004-08-20 2005-08-18 Rapamycin polymorph ii and uses thereof

Publications (1)

Publication Number Publication Date
BRPI0514407A true BRPI0514407A (pt) 2008-06-10

Family

ID=35431373

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0514407-8A BRPI0514407A (pt) 2004-08-20 2005-08-18 forma ii de polimorfo de rapamicina, processos para preparar a forma ii do polimorfo de rapaminicina, e a forma i do polimorfo de rapamicina, composição farmacêutica, kit, e, método para preparar uma composição farmacêutica

Country Status (22)

Country Link
US (1) US7282505B2 (pt)
EP (1) EP1781671A1 (pt)
JP (1) JP2008510710A (pt)
KR (1) KR20070051863A (pt)
CN (1) CN101039948A (pt)
AR (1) AR050374A1 (pt)
AU (1) AU2005277407A1 (pt)
BR (1) BRPI0514407A (pt)
CA (1) CA2575887A1 (pt)
CR (1) CR8929A (pt)
EC (1) ECSP077268A (pt)
GT (1) GT200500223A (pt)
IL (1) IL181170A0 (pt)
MX (1) MX2007002044A (pt)
NO (1) NO20071050L (pt)
PA (1) PA8642501A1 (pt)
PE (1) PE20060649A1 (pt)
RU (1) RU2007104518A (pt)
SV (1) SV2006002201A (pt)
TW (1) TW200608973A (pt)
WO (1) WO2006023627A1 (pt)
ZA (1) ZA200701453B (pt)

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JP2007505932A (ja) 2003-09-18 2007-03-15 マクサイト， インコーポレイテッド 経強膜送達
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US8551512B2 (en) * 2004-03-22 2013-10-08 Advanced Cardiovascular Systems, Inc. Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS
CA2597590A1 (en) 2005-02-09 2006-08-17 Macusight, Inc. Formulations for ocular treatment
US8663639B2 (en) 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
KR101478164B1 (ko) 2006-02-09 2014-12-31 산텐 세이야꾸 가부시키가이샤 안정한 제제와 그 제조 및 사용 방법
AU2007230964B2 (en) 2006-03-23 2012-07-19 Santen Pharmaceutical Co., Ltd. Formulations and methods for vascular permeability-related diseases or conditions
US7820812B2 (en) 2006-07-25 2010-10-26 Abbott Laboratories Methods of manufacturing crystalline forms of rapamycin analogs
US7812032B2 (en) 2006-07-25 2010-10-12 Abbott Laboratories Crystalline forms of rapamycin analogs
EP2051984A1 (en) * 2006-07-25 2009-04-29 Abbott Laboratories Crystalline forms of rapamycin analogs
US8486926B2 (en) * 2006-11-17 2013-07-16 Harbor Therapeutics, Inc. Steroid tetrol solid state forms
US8414525B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8414909B2 (en) * 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8430055B2 (en) 2008-08-29 2013-04-30 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US9737640B2 (en) 2006-11-20 2017-08-22 Lutonix, Inc. Drug releasing coatings for medical devices
US9700704B2 (en) 2006-11-20 2017-07-11 Lutonix, Inc. Drug releasing coatings for balloon catheters
US20080276935A1 (en) 2006-11-20 2008-11-13 Lixiao Wang Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US8414910B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8425459B2 (en) 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US8998846B2 (en) 2006-11-20 2015-04-07 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8414526B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
JP2008305262A (ja) * 2007-06-08 2008-12-18 Konica Minolta Business Technologies Inc サーバ及びシンクライアント環境でのプリンタ紹介方法
CA2937492C (en) 2008-11-11 2019-08-13 The Board Of Regents Of The University Of Texas System Inhibition of mammalian target of rapamycin
DE102008060549A1 (de) 2008-12-04 2010-06-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
CA2749807C (en) * 2009-01-21 2015-09-29 Biocon Limited A method for determination of sirolimus stability and process for preparing its stable form
US20120231037A1 (en) 2009-02-02 2012-09-13 Yissum Research Development Companyof the Hebrew U Crystalline drug-containing coatings
WO2011049659A2 (en) * 2009-08-05 2011-04-28 The Government Of United States, As Represented By The Secretary Of The Army Novel use and method of rapamycin to treat toxic shock
US10391059B2 (en) 2009-11-11 2019-08-27 Rapamycin Holdings, Inc. Oral rapamycin nanoparticle preparations and use
US9283211B1 (en) 2009-11-11 2016-03-15 Rapamycin Holdings, Llc Oral rapamycin preparation and use for stomatitis
US20140343128A1 (en) 2011-11-15 2014-11-20 Novartis Ag Combination of a phosphoinositide 3-kinase inhibitor and a modulator of the Janus Kinase 2 - Signal Transducer and Activator of Transcription 5 pathway
US20150224190A1 (en) 2012-07-06 2015-08-13 Mohamed Bentires-Alj Combination of a phosphoinositide 3-kinase inhibitor and an inhibitor of the IL-8/CXCR interaction
US20160030401A1 (en) 2013-03-13 2016-02-04 The Board Of Regents Of The University Of Texas System Use of mtor inhibitors for prevention of intestinal polyp growth and cancer
CN106061482A (zh) 2013-10-08 2016-10-26 拉姆医疗公司 用于治疗淋巴管平滑肌瘤病的雷帕霉素
US9700544B2 (en) 2013-12-31 2017-07-11 Neal K Vail Oral rapamycin nanoparticle preparations
US10307371B2 (en) 2014-02-11 2019-06-04 AI Therapeutics, Inc. Rapamycin for the treatment of lymphangioleiomyomatosis
RU2016136348A (ru) * 2014-02-11 2018-03-16 Лэм Терапьютикс, Инк. Рапамицин для лечения лимфангиолейомиоматоза
HUP1400075A2 (hu) 2014-02-14 2015-08-28 Druggability Technologies Ip Holdco Jersey Ltd Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói
NZ724756A (en) 2014-04-04 2023-07-28 Ai Therapeutics Inc An inhalable rapamycin formulation for treating age-related conditions
CA2963085C (en) 2014-10-07 2023-02-21 Lam Therapeutics, Inc. An inhalable rapamycin formulation for the treatment of pulmonary hypertension
MA40910A (fr) 2014-11-07 2017-09-12 Civitas Therapeutics Inc Poudres de rapamycine pour administration pulmonaire
CN106478663A (zh) * 2015-08-26 2017-03-08 博瑞生物医药（苏州）股份有限公司 一种依维莫司的干燥方法
EP3848065B1 (en) 2017-05-15 2023-07-26 C. R. Bard, Inc. Medical device with drug-eluting coating and intermediate layer
CN109020995A (zh) * 2017-06-12 2018-12-18 鲁南制药集团股份有限公司 一种替西罗莫司的晶型物
JP7262581B2 (ja) 2018-11-14 2023-04-21 ルトニックス，インコーポレーテッド 改質されたデバイス表面に薬物溶出コーティングを有する医療用デバイス
CN113939324A (zh) 2019-04-08 2022-01-14 巴德外周血管股份有限公司 在经改性装置表面上具有药物洗脱涂层的医疗装置

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US3993749A (en) 1974-04-12 1976-11-23 Ayerst Mckenna And Harrison Ltd. Rapamycin and process of preparation
UA41884C2 (uk) * 1993-11-05 2001-10-15 Амерікан Хоум Продактс Корпорейшн Спосіб відокремлення рапаміцину від кислотних, основних та неполярних нейтральних домішок, присутніх в концентраті екстрактів ферментаційного бульйону або маточних розчинів

Also Published As

Publication number Publication date
US7282505B2 (en) 2007-10-16
EP1781671A1 (en) 2007-05-09
GT200500223A (es) 2006-03-09
IL181170A0 (en) 2007-07-04
ECSP077268A (es) 2007-03-29
WO2006023627A8 (en) 2006-11-30
NO20071050L (no) 2007-05-15
PA8642501A1 (es) 2006-05-16
WO2006023627A1 (en) 2006-03-02
AR050374A1 (es) 2006-10-18
CA2575887A1 (en) 2006-03-02
RU2007104518A (ru) 2008-09-27
MX2007002044A (es) 2007-03-29
TW200608973A (en) 2006-03-16
KR20070051863A (ko) 2007-05-18
US20060040971A1 (en) 2006-02-23
AU2005277407A1 (en) 2006-03-02
PE20060649A1 (es) 2006-08-10
SV2006002201A (es) 2006-05-09
CR8929A (es) 2007-08-28
CN101039948A (zh) 2007-09-19
ZA200701453B (en) 2010-08-25
JP2008510710A (ja) 2008-04-10

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.