NO20071050L - Rapamycin-polymorf II og anvendelser derav - Google Patents

Rapamycin-polymorf II og anvendelser derav

Info

Publication number: NO20071050L
Authority: NO; Norway
Prior art keywords: rapamycin; polymorphic form; rapamycin polymorph; provides; polymorph
Prior art date: 2004-08-20

Application number

NO20071050A

Other languages

English (en)

Norwegian (no)

Inventor

Mahdi Fawzi

Tianmin Zhu

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-08-20

Filing date

2007-02-23

Publication date

2007-05-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35431373&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20071050(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2007-02-23 Application filed by Wyeth Corp filed Critical Wyeth Corp

2007-05-15 Publication of NO20071050L publication Critical patent/NO20071050L/no

Links

ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 title abstract 4
QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 title abstract 4
229960002930 sirolimus Drugs 0.000 title abstract 4
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20071050A 2004-08-20 2007-02-23 Rapamycin-polymorf II og anvendelser derav NO20071050L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US60309604P	2004-08-20	2004-08-20
PCT/US2005/029364 WO2006023627A1 (en)	2004-08-20	2005-08-18	Rapamycin polymorph ii and uses thereof

Publications (1)

Publication Number	Publication Date
NO20071050L true NO20071050L (no)	2007-05-15

Family

ID=35431373

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20071050A NO20071050L (no)	2004-08-20	2007-02-23	Rapamycin-polymorf II og anvendelser derav

Country Status (22)

Country	Link
US (1)	US7282505B2 (pt)
EP (1)	EP1781671A1 (pt)
JP (1)	JP2008510710A (pt)
KR (1)	KR20070051863A (pt)
CN (1)	CN101039948A (pt)
AR (1)	AR050374A1 (pt)
AU (1)	AU2005277407A1 (pt)
BR (1)	BRPI0514407A (pt)
CA (1)	CA2575887A1 (pt)
CR (1)	CR8929A (pt)
EC (1)	ECSP077268A (pt)
GT (1)	GT200500223A (pt)
IL (1)	IL181170A0 (pt)
MX (1)	MX2007002044A (pt)
NO (1)	NO20071050L (pt)
PA (1)	PA8642501A1 (pt)
PE (1)	PE20060649A1 (pt)
RU (1)	RU2007104518A (pt)
SV (1)	SV2006002201A (pt)
TW (1)	TW200608973A (pt)
WO (1)	WO2006023627A1 (pt)
ZA (1)	ZA200701453B (pt)

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AR040693A1 (es)	2002-07-30	2005-04-13	Wyeth Corp	Formulaciones parenterales
KR20060085246A (ko)	2003-09-18	2006-07-26	마커사이트, 인코포레이티드	경공막 전달
US7349971B2 (en) *	2004-02-05	2008-03-25	Scenera Technologies, Llc	System for transmitting data utilizing multiple communication applications simultaneously in response to user request without specifying recipient's communication information
US8551512B2 (en) *	2004-03-22	2013-10-08	Advanced Cardiovascular Systems, Inc.	Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS
US8663639B2 (en)	2005-02-09	2014-03-04	Santen Pharmaceutical Co., Ltd.	Formulations for treating ocular diseases and conditions
DK1848431T3 (en)	2005-02-09	2016-04-18	Santen Pharmaceutical Co Ltd	LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS
KR20140093764A (ko)	2006-02-09	2014-07-28	산텐 세이야꾸 가부시키가이샤	안정한 제제와 그 제조 및 사용 방법
ES2563288T3 (es)	2006-03-23	2016-03-14	Santen Pharmaceutical Co., Ltd	Rapamicina en dosis bajas para el tratamiento de enfermedades relacionadas con la permeabilidad vascular
JP2010500286A (ja) *	2006-07-25	2010-01-07	アボット・ラボラトリーズ	結晶形態のラパマイシン類似体
US7820812B2 (en)	2006-07-25	2010-10-26	Abbott Laboratories	Methods of manufacturing crystalline forms of rapamycin analogs
US7812032B2 (en)	2006-07-25	2010-10-12	Abbott Laboratories	Crystalline forms of rapamycin analogs
US8486926B2 (en) *	2006-11-17	2013-07-16	Harbor Therapeutics, Inc.	Steroid tetrol solid state forms
US8414526B2 (en)	2006-11-20	2013-04-09	Lutonix, Inc.	Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
US20080276935A1 (en)	2006-11-20	2008-11-13	Lixiao Wang	Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US9700704B2 (en)	2006-11-20	2017-07-11	Lutonix, Inc.	Drug releasing coatings for balloon catheters
US8998846B2 (en)	2006-11-20	2015-04-07	Lutonix, Inc.	Drug releasing coatings for balloon catheters
US8425459B2 (en)	2006-11-20	2013-04-23	Lutonix, Inc.	Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US8414525B2 (en)	2006-11-20	2013-04-09	Lutonix, Inc.	Drug releasing coatings for medical devices
US8430055B2 (en)	2008-08-29	2013-04-30	Lutonix, Inc.	Methods and apparatuses for coating balloon catheters
US8414909B2 (en)	2006-11-20	2013-04-09	Lutonix, Inc.	Drug releasing coatings for medical devices
US8414910B2 (en) *	2006-11-20	2013-04-09	Lutonix, Inc.	Drug releasing coatings for medical devices
US9737640B2 (en)	2006-11-20	2017-08-22	Lutonix, Inc.	Drug releasing coatings for medical devices
JP2008305262A (ja) *	2007-06-08	2008-12-18	Konica Minolta Business Technologies Inc	サーバ及びシンクライアント環境でのプリンタ紹介方法
ES2645692T3 (es)	2008-11-11	2017-12-07	The Board Of Regents,The University Of Texas System	Microcápsulas de rapamicina y su uso para el tratamiento del cáncer
DE102008060549A1 (de)	2008-12-04	2010-06-10	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
CN102282457A (zh) *	2009-01-21	2011-12-14	拜康有限公司	确定西罗莫司稳定性的方法和制备其稳定形式的工艺
WO2010086863A2 (en)	2009-02-02	2010-08-05	Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd.	Crystalline drug-containing coatings
US20120252834A1 (en) *	2009-08-05	2012-10-04	The Government Of United States, As Represented By The Secretary Of The Army	Novel use and method of rapamycin to treat toxic shock
US9283211B1 (en)	2009-11-11	2016-03-15	Rapamycin Holdings, Llc	Oral rapamycin preparation and use for stomatitis
US20140343128A1 (en)	2011-11-15	2014-11-20	Novartis Ag	Combination of a phosphoinositide 3-kinase inhibitor and a modulator of the Janus Kinase 2 - Signal Transducer and Activator of Transcription 5 pathway
US20150224190A1 (en)	2012-07-06	2015-08-13	Mohamed Bentires-Alj	Combination of a phosphoinositide 3-kinase inhibitor and an inhibitor of the IL-8/CXCR interaction
WO2014160328A1 (en)	2013-03-13	2014-10-02	The Board Of Regents Of The University Of Texas System	Mtor inhibitors for prevention of intestinal polyp growth
JP6529012B2 (ja)	2013-10-08	2019-06-12	エイアイ・セラピューティクス・インコーポレーテッド	リンパ脈管筋腫症の処置のためのラパマイシン
US9700544B2 (en)	2013-12-31	2017-07-11	Neal K Vail	Oral rapamycin nanoparticle preparations
EP3089737B1 (en)	2013-12-31	2021-11-03	Rapamycin Holdings, LLC	Oral rapamycin nanoparticle preparations and use
MX2016010373A (es) *	2014-02-11	2016-11-30	Lam Therapeutics Inc	Rapamicina para el tratamiento de linfangioleiomiomatosis.
US10307371B2 (en)	2014-02-11	2019-06-04	AI Therapeutics, Inc.	Rapamycin for the treatment of lymphangioleiomyomatosis
HUP1400075A2 (hu)	2014-02-14	2015-08-28	Druggability Technologies Ip Holdco Jersey Ltd	Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói
NZ724756A (en)	2014-04-04	2023-07-28	Ai Therapeutics Inc	An inhalable rapamycin formulation for treating age-related conditions
RU2732908C2 (ru)	2014-10-07	2020-09-24	ЭйАй ТЕРАПЬЮТИКС, ИНК.	Ингаляционная лекарственная форма рапамицина для лечения легочной гипертензии
MA40910A (fr)	2014-11-07	2017-09-12	Civitas Therapeutics Inc	Poudres de rapamycine pour administration pulmonaire
CN106478663A (zh) *	2015-08-26	2017-03-08	博瑞生物医药（苏州）股份有限公司	一种依维莫司的干燥方法
US20210154372A1 (en)	2017-05-15	2021-05-27	C.R. Bard, Inc.	Medical device with drug-eluting coating and intermediate layer
CN109020995A (zh) *	2017-06-12	2018-12-18	鲁南制药集团股份有限公司	一种替西罗莫司的晶型物
EP3880266B1 (en)	2018-11-14	2025-05-07	Lutonix, Inc.	Medical device with drug-eluting coating on modified device surface
EP3952937A1 (en)	2019-04-08	2022-02-16	Bard Peripheral Vascular, Inc.	Medical device with drug-eluting coating on modified device surface

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA737247B (en) *	1972-09-29	1975-04-30	Ayerst Mckenna & Harrison	Rapamycin and process of preparation
US3993749A (en)	1974-04-12	1976-11-23	Ayerst Mckenna And Harrison Ltd.	Rapamycin and process of preparation
UA41884C2 (uk) *	1993-11-05	2001-10-15	Амерікан Хоум Продактс Корпорейшн	Спосіб відокремлення рапаміцину від кислотних, основних та неполярних нейтральних домішок, присутніх в концентраті екстрактів ферментаційного бульйону або маточних розчинів

2005
- 2005-08-16 AR ARP050103448A patent/AR050374A1/es unknown
- 2005-08-18 RU RU2007104518/04A patent/RU2007104518A/ru not_active Application Discontinuation
- 2005-08-18 MX MX2007002044A patent/MX2007002044A/es unknown
- 2005-08-18 WO PCT/US2005/029364 patent/WO2006023627A1/en not_active Ceased
- 2005-08-18 SV SV2005002201A patent/SV2006002201A/es unknown
- 2005-08-18 KR KR1020077003941A patent/KR20070051863A/ko not_active Withdrawn
- 2005-08-18 TW TW094128147A patent/TW200608973A/zh unknown
- 2005-08-18 US US11/206,472 patent/US7282505B2/en not_active Expired - Fee Related
- 2005-08-18 CN CNA2005800353638A patent/CN101039948A/zh active Pending
- 2005-08-18 PE PE2005000957A patent/PE20060649A1/es not_active Application Discontinuation
- 2005-08-18 JP JP2007528004A patent/JP2008510710A/ja not_active Withdrawn
- 2005-08-18 AU AU2005277407A patent/AU2005277407A1/en not_active Abandoned
- 2005-08-18 EP EP05788650A patent/EP1781671A1/en not_active Withdrawn
- 2005-08-18 PA PA20058642501A patent/PA8642501A1/es unknown
- 2005-08-18 GT GT200500223A patent/GT200500223A/es unknown
- 2005-08-18 CA CA002575887A patent/CA2575887A1/en not_active Abandoned
- 2005-08-18 BR BRPI0514407-8A patent/BRPI0514407A/pt not_active IP Right Cessation
2007
- 2007-02-05 IL IL181170A patent/IL181170A0/en unknown
- 2007-02-15 CR CR8929A patent/CR8929A/es not_active Application Discontinuation
- 2007-02-19 ZA ZA200701453A patent/ZA200701453B/xx unknown
- 2007-02-21 EC EC2007007268A patent/ECSP077268A/es unknown
- 2007-02-23 NO NO20071050A patent/NO20071050L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
PE20060649A1 (es)	2006-08-10
RU2007104518A (ru)	2008-09-27
SV2006002201A (es)	2006-05-09
ZA200701453B (en)	2010-08-25
GT200500223A (es)	2006-03-09
JP2008510710A (ja)	2008-04-10
EP1781671A1 (en)	2007-05-09
CA2575887A1 (en)	2006-03-02
PA8642501A1 (es)	2006-05-16
KR20070051863A (ko)	2007-05-18
CN101039948A (zh)	2007-09-19
MX2007002044A (es)	2007-03-29
WO2006023627A1 (en)	2006-03-02
CR8929A (es)	2007-08-28
IL181170A0 (en)	2007-07-04
ECSP077268A (es)	2007-03-29
BRPI0514407A (pt)	2008-06-10
AR050374A1 (es)	2006-10-18
US7282505B2 (en)	2007-10-16
TW200608973A (en)	2006-03-16
US20060040971A1 (en)	2006-02-23
AU2005277407A1 (en)	2006-03-02
WO2006023627A8 (en)	2006-11-30

Legal Events

Date	Code	Title	Description
2010-03-22	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20071050L (no)	2007-05-15	Rapamycin-polymorf II og anvendelser derav
MX2007005221A (es)	2007-06-22	Formas cristalinas de ascomicina y preparacion de ellas.
SE0301372D0 (sv)	2003-05-09	Novel compounds
WO2006050161A3 (en)	2007-12-21	Therapeutic furopyrimidines and thienopyrimidines
CY1112402T1 (el)	2015-12-09	Ενισχυτες υποδοχεων γλουταμικου
WO2009067674A3 (en)	2009-08-27	Polymorphs of sunitinib base and processes for preparation thereof
ATE528989T1 (de)	2011-11-15	Kristalline feste rasagilin-base
SE0301373D0 (sv)	2003-05-09	Novel compounds
EA200971051A1 (ru)	2010-06-30	Ингибиторы p70 s6 киназы
DK1695710T3 (da)	2008-09-22	Krystallinsk betad-form af ivabradinhydrochlorid, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende denne
MX2009000884A (es)	2009-06-05	Derivados de piridizinona.
WO2008005877A3 (en)	2008-03-27	Inhibitors of c-kit and uses thereof
WO2009146218A3 (en)	2010-04-15	Compounds including an anti-inflammatory pharmacore and methods of use
BRPI0818672A2 (pt)	2015-04-14	2'-fluor-2'-desoxitetra-hidrouridinas como inibidores da citidina desaminase
DK3530673T3 (da)	2022-04-19	Humaniserede anti-beta7-antagonister og anvendelser deraf
ECSP045088A (es)	2004-06-28	Forma polimorfica de rimonabant, su procedimiento de preparacion y composiciones farmaceuticas que la contienen
UA86591C2 (ru)	2009-05-12	Пирролодигидроизохинолины как ингибиторы pde10, фармацевтическая композиция на их основе
DK2054418T3 (da)	2012-02-27	Dihydrothieno-pyrimidiner som AKT-proteinkinase-inhibitorer
NO20073725L (no)	2007-09-05	CCI-779-polymorf og dens anvendelse
WO2007064553A3 (en)	2008-07-10	Thiazole derivatives as cxcr3 receptor modulators
WO2007070433A3 (en)	2008-02-21	2-arylthiazole derivatives as cxcr3 receptor modulators
MX2009004290A (es)	2009-07-27	Inhibidores de proteasas de catepsina.
TW200613308A (en)	2006-05-01	Cyclobutanetetracarboxylate compound and preparation method thereof
TNSN06321A1 (en)	2008-02-22	Beta-carbolines useful for treating inflammatory disease
TWI374886B (en)	2012-10-21	Processes for preparing intermediates of pemetrexed