BRPI0514843A - derivados de pirrolo[3,2-c] piridina e processos para a preparação dos mesmos - Google Patents

derivados de pirrolo[3,2-c] piridina e processos para a preparação dos mesmos

Info

Publication number
BRPI0514843A
BRPI0514843A BRPI0514843-0A BRPI0514843A BRPI0514843A BR PI0514843 A BRPI0514843 A BR PI0514843A BR PI0514843 A BRPI0514843 A BR PI0514843A BR PI0514843 A BRPI0514843 A BR PI0514843A
Authority
BR
Brazil
Prior art keywords
pyrrolo
pyridine derivatives
processes
preparation
pharmaceutically acceptable
Prior art date
Application number
BRPI0514843-0A
Other languages
English (en)
Inventor
Jae-Gyu Kim
Byung-Nak Ahn
Hyouk-Woo Lee
Suk-Won Yoon
Young-Ae Yoon
Dong-Hoon Kim
Se-Hoon Keum
Young-Ah Shin
Heui-Il Kang
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of BRPI0514843A publication Critical patent/BRPI0514843A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A presente invenção proporciona novos derivados de pirrolo¢3,2-c! piridina ou seus sais farmaceuticamente aceitáveis, processos para a preparação destes, e composições compreendendo os mesmos. Os derivados de pirrolo¢3,2-c! piridina ou os seus sais farmaceuticamente aceitáveis da presente invenção têm excelentes efeitos de inibição da bomba de prótons e possuem a capacidade de atingir um efeito inibitório reversível da bomba de prótons.
BRPI0514843-0A 2004-09-03 2005-09-03 derivados de pirrolo[3,2-c] piridina e processos para a preparação dos mesmos BRPI0514843A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20040070536 2004-09-03
PCT/KR2005/002924 WO2006025714A1 (en) 2004-09-03 2005-09-03 PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF

Publications (1)

Publication Number Publication Date
BRPI0514843A true BRPI0514843A (pt) 2008-06-24

Family

ID=36000316

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0514843-0A BRPI0514843A (pt) 2004-09-03 2005-09-03 derivados de pirrolo[3,2-c] piridina e processos para a preparação dos mesmos

Country Status (16)

Country Link
US (2) US8148529B2 (pt)
EP (1) EP1784402B1 (pt)
JP (1) JP5126830B2 (pt)
KR (1) KR100946219B1 (pt)
CN (1) CN101018788B (pt)
AT (1) ATE518858T1 (pt)
AU (1) AU2005280738B2 (pt)
BR (1) BRPI0514843A (pt)
CA (1) CA2578880C (pt)
DK (1) DK1784402T3 (pt)
ES (1) ES2367312T3 (pt)
MX (1) MX2007002214A (pt)
PL (1) PL1784402T3 (pt)
PT (1) PT1784402E (pt)
RU (1) RU2378275C2 (pt)
WO (1) WO2006025714A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008017466A1 (en) * 2006-08-08 2008-02-14 Nycomed Gmbh Pharmaceutically active tetrahydroisoquinoline-substituted benzimidazole derivatives
MX2012000275A (es) 2009-07-09 2012-02-08 Raqualia Pharma Inc Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal.
TWI636047B (zh) 2013-08-14 2018-09-21 英商卡爾維斯塔製藥有限公司 雜環衍生物
GB2517908A (en) 2013-08-14 2015-03-11 Kalvista Pharmaceuticals Ltd Bicyclic inhibitors
CN103626767A (zh) * 2013-12-04 2014-03-12 上海药明康德新药开发有限公司 区域选择性的氮杂吲哚及其合成方法
GB201421083D0 (en) 2014-11-27 2015-01-14 Kalvista Pharmaceuticals Ltd Enzyme inhibitors
SG10201912902TA (en) 2015-10-09 2020-02-27 Wave Life Sciences Ltd Oligonucleotide compositions and methods thereof
RS60600B1 (sr) 2016-05-31 2020-08-31 Kalvista Pharmaceuticals Ltd Derivati pirazola kao inhibitori kalikreina plazme
GB201609607D0 (en) 2016-06-01 2016-07-13 Kalvista Pharmaceuticals Ltd Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts
IL274557B2 (en) 2017-11-29 2024-09-01 Kalvista Pharmaceuticals Ltd Dosage forms comprising a plasma kallikrein inhibitor
GB201719881D0 (en) 2017-11-29 2018-01-10 Kalvista Pharmaceuticals Ltd Solid forms of plasma kallikrein inhibitor and salts thereof
CN114206852A (zh) 2019-08-09 2022-03-18 卡尔维斯塔制药有限公司 血浆激肽释放酶抑制剂

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068378B1 (en) 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
JP3465827B2 (ja) * 1993-02-24 2003-11-10 株式会社日清製粉グループ本社 アザインドール誘導体およびこれを有効成分とする抗潰瘍薬
US5451566A (en) * 1993-11-17 1995-09-19 Zeneca Limited Herbicidal pyrrolopyridine compounds
CZ283216B6 (cs) * 1994-01-19 1998-02-18 Sankyo, Company Limited Pyrrolopyridazinové deriváty
CN1102144C (zh) 1994-08-13 2003-02-26 株式会社柳韩洋行 新的嘧啶衍生物及其制备方法
EP0849274A1 (en) * 1996-12-20 1998-06-24 Schering Aktiengesellschaft Bissteroidal compounds and their use for the preparation of chiral complexes
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
SE9704404D0 (sv) * 1997-11-28 1997-11-28 Astra Ab New compounds
WO1999037304A1 (en) * 1998-01-27 1999-07-29 Aventis Pharmaceuticals Products Inc. SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS
BR9914044A (pt) 1998-09-23 2001-12-04 Byk Gulden Lomberg Chem Fab ésteres tetrahidropirido
US20040110785A1 (en) * 2001-02-02 2004-06-10 Tao Wang Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
US20040235867A1 (en) * 2001-07-24 2004-11-25 Bilodeau Mark T. Tyrosine kinase inhibitors

Also Published As

Publication number Publication date
RU2378275C2 (ru) 2010-01-10
PL1784402T3 (pl) 2011-12-30
US8148529B2 (en) 2012-04-03
EP1784402A4 (en) 2009-12-23
ES2367312T3 (es) 2011-11-02
AU2005280738A1 (en) 2006-03-09
CA2578880C (en) 2013-01-29
EP1784402B1 (en) 2011-08-03
JP2008511618A (ja) 2008-04-17
CN101018788B (zh) 2010-08-25
AU2005280738B2 (en) 2010-11-25
RU2007112108A (ru) 2008-10-10
CA2578880A1 (en) 2006-03-09
WO2006025714A1 (en) 2006-03-09
ATE518858T1 (de) 2011-08-15
KR20060051002A (ko) 2006-05-19
US8513277B2 (en) 2013-08-20
US20090005409A1 (en) 2009-01-01
EP1784402A1 (en) 2007-05-16
PT1784402E (pt) 2011-08-23
CN101018788A (zh) 2007-08-15
DK1784402T3 (da) 2011-11-14
KR100946219B1 (ko) 2010-03-08
MX2007002214A (es) 2007-05-07
US20120065224A1 (en) 2012-03-15
HK1105977A1 (en) 2008-02-29
JP5126830B2 (ja) 2013-01-23

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]