BRPI0515494A - uso de [d-meala] 3-[etval] 4-ciclosporina para o tratamento de infecção por hepatite c e composição farmacêutica compreendendo a referida [d-meala] 3-[etval] 4-ciclosporina - Google Patents

uso de [d-meala] 3-[etval] 4-ciclosporina para o tratamento de infecção por hepatite c e composição farmacêutica compreendendo a referida [d-meala] 3-[etval] 4-ciclosporina

Info

Publication number
BRPI0515494A
BRPI0515494A BRPI0515494-4A BRPI0515494A BRPI0515494A BR PI0515494 A BRPI0515494 A BR PI0515494A BR PI0515494 A BRPI0515494 A BR PI0515494A BR PI0515494 A BRPI0515494 A BR PI0515494A
Authority
BR
Brazil
Prior art keywords
etval
meala
cyclosporine
treatment
infection
Prior art date
Application number
BRPI0515494-4A
Other languages
English (en)
Inventor
Pietro Scalfaro
Jean-Maurice Dumont
Gregoire Vuagniaux
Rolland-Yves Mauvernay
Original Assignee
Debiopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Sa filed Critical Debiopharm Sa
Publication of BRPI0515494A publication Critical patent/BRPI0515494A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"USO DE ¢D-MEALA! 3-¢ETVAL!4-CICLOSPORINA PARA O TRATAMENTO DE INFECçãO POR HEPATITE C E COMPOSIçãO FARMACêUTICA COMPREENDENDO A REFERIDA ¢D-MEALA!3-¢ETVAL!4-CICLOSPORINA". A presente invenção refere-se ao uso, no tratamento de infecção por HCV, de uma ciclosporina, seja como agentes ativos individuais ou em combinação com um outro agente ativo, dotada de atividade de ligação à ciclofilina aumentada, e, carecendo essencialmente, de atividade imunossupressora.
BRPI0515494-4A 2004-10-01 2005-10-03 uso de [d-meala] 3-[etval] 4-ciclosporina para o tratamento de infecção por hepatite c e composição farmacêutica compreendendo a referida [d-meala] 3-[etval] 4-ciclosporina BRPI0515494A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2004003205 2004-10-01
PCT/IB2005/002940 WO2006038088A1 (en) 2004-10-01 2005-10-03 Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection and pharmaceutical composition comprising said [d-meala]3-[etval]4-cyclosporin

Publications (1)

Publication Number Publication Date
BRPI0515494A true BRPI0515494A (pt) 2008-07-29

Family

ID=34959441

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0515494-4A BRPI0515494A (pt) 2004-10-01 2005-10-03 uso de [d-meala] 3-[etval] 4-ciclosporina para o tratamento de infecção por hepatite c e composição farmacêutica compreendendo a referida [d-meala] 3-[etval] 4-ciclosporina

Country Status (29)

Country Link
US (3) US7439227B2 (pt)
EP (1) EP1793844B1 (pt)
JP (1) JP4892486B2 (pt)
KR (1) KR101191833B1 (pt)
CN (1) CN101056648B (pt)
AT (1) ATE490778T1 (pt)
AU (1) AU2005290984B2 (pt)
BR (1) BRPI0515494A (pt)
CA (1) CA2580448C (pt)
CY (1) CY1114594T1 (pt)
DE (1) DE602005025232D1 (pt)
DK (1) DK1793844T3 (pt)
EA (1) EA012650B1 (pt)
ES (1) ES2357587T3 (pt)
GE (1) GEP20104960B (pt)
HR (1) HRP20110169T1 (pt)
IL (1) IL182362A0 (pt)
MA (1) MA28950B1 (pt)
MX (1) MX2007003387A (pt)
NZ (1) NZ554412A (pt)
PL (1) PL1793844T3 (pt)
PT (1) PT1793844E (pt)
RS (1) RS51614B (pt)
SG (1) SG139750A1 (pt)
SI (1) SI1793844T1 (pt)
TN (1) TNSN07084A1 (pt)
UA (1) UA88484C2 (pt)
WO (1) WO2006038088A1 (pt)
ZA (1) ZA200702610B (pt)

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KR101273681B1 (ko) 2005-10-26 2013-06-25 아스텔라스세이야쿠 가부시키가이샤 신규 시클릭 펩티드 화합물
AU2007249668B2 (en) 2006-04-11 2011-04-07 Novartis Ag HCV/HIV inhibitors and their uses
DK2023918T3 (da) 2006-05-19 2011-04-26 Scynexis Inc Cyclosporiner til behandlingen og forebyggelse af okulære lidelser
KR20090083902A (ko) * 2006-10-12 2009-08-04 노파르티스 아게 개질된 사이클로스포린의 용도
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
AU2008250254B2 (en) 2007-05-02 2012-08-16 Astellas Pharma Inc. New cyclic peptide compounds
US8394763B2 (en) 2007-09-26 2013-03-12 Oregon Health & Science University Cyclic undecapeptides and derivatives as multiple sclerosis therapies
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US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
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US20110117055A1 (en) 2009-11-19 2011-05-19 Macdonald James E Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
CN102869367A (zh) 2009-12-09 2013-01-09 西尼克斯公司 新颖的环肽
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
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WO2012009715A2 (en) 2010-07-16 2012-01-19 S&T Global Inc. Novel cyclosporin derivatives for the treatment and prevention of a viral infection
US9573978B2 (en) 2010-08-12 2017-02-21 S&T Global, Inc. Cyclosporin derivatives for the treatment and prevention of a viral infection
JP2013542206A (ja) * 2010-10-05 2013-11-21 ノバルティス アーゲー Ｃ型肝炎ウイルス感染症の新規治療
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CA2832829A1 (en) 2011-04-13 2012-10-18 Novartis Ag Treatment of hepatitis c virus infection with alisporivir
JP2014528947A (ja) 2011-09-27 2014-10-30 ノバルティス アーゲー Ｃ型肝炎ウイルス感染症の治療のためのアリスポリビル
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GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
ES2357587T3 (es) 2011-04-27
HK1104236A1 (en) 2008-01-11
US7772184B2 (en) 2010-08-10
DE602005025232D1 (de) 2011-01-20
CN101056648B (zh) 2012-08-15
EP1793844A1 (en) 2007-06-13
AU2005290984B2 (en) 2010-09-09
AU2005290984A1 (en) 2006-04-13
NZ554412A (en) 2011-01-28
US7439227B2 (en) 2008-10-21
JP4892486B2 (ja) 2012-03-07
ZA200702610B (en) 2008-08-27
RS51614B (sr) 2011-08-31
IL182362A0 (en) 2007-07-24
CN101056648A (zh) 2007-10-17
ATE490778T1 (de) 2010-12-15
HRP20110169T1 (hr) 2011-04-30
UA88484C2 (ru) 2009-10-26
PT1793844E (pt) 2011-03-10
GEP20104960B (en) 2010-04-26
MX2007003387A (es) 2007-05-23
JP2008514690A (ja) 2008-05-08
CA2580448C (en) 2012-09-18
EA200700725A1 (ru) 2007-10-26
EA012650B1 (ru) 2009-12-30
KR101191833B1 (ko) 2012-10-16
KR20070073761A (ko) 2007-07-10
USRE43371E1 (en) 2012-05-08
WO2006038088A1 (en) 2006-04-13
CY1114594T1 (el) 2016-10-05
US20090081164A1 (en) 2009-03-26
SG139750A1 (en) 2008-02-29
TNSN07084A1 (en) 2008-06-02
MA28950B1 (fr) 2007-10-01
DK1793844T3 (da) 2011-03-21
US20060252675A1 (en) 2006-11-09
SI1793844T1 (sl) 2011-05-31
CA2580448A1 (en) 2006-04-13
PL1793844T3 (pl) 2011-05-31
EP1793844B1 (en) 2010-12-08

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B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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