ATE314092T1 - Biologische kleber und verfahren zur topischen verabreichung von wirkstoffen - Google Patents

Biologische kleber und verfahren zur topischen verabreichung von wirkstoffen

Info

Publication number
ATE314092T1
ATE314092T1 AT98949505T AT98949505T ATE314092T1 AT E314092 T1 ATE314092 T1 AT E314092T1 AT 98949505 T AT98949505 T AT 98949505T AT 98949505 T AT98949505 T AT 98949505T AT E314092 T1 ATE314092 T1 AT E314092T1
Authority
AT
Austria
Prior art keywords
composition
active ingredients
bioadhesive
active agent
topical administration
Prior art date
Application number
AT98949505T
Other languages
English (en)
Inventor
Juan Mantelle
David Houze
David Kanios
Original Assignee
Noven Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22033995&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE314092(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Noven Pharma filed Critical Noven Pharma
Application granted granted Critical
Publication of ATE314092T1 publication Critical patent/ATE314092T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
AT98949505T 1997-09-26 1998-09-25 Biologische kleber und verfahren zur topischen verabreichung von wirkstoffen ATE314092T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6115597P 1997-09-26 1997-09-26
PCT/US1998/020091 WO1999015210A2 (en) 1997-09-26 1998-09-25 Bioadhesive compositions and methods for topical administration of active agents

Publications (1)

Publication Number Publication Date
ATE314092T1 true ATE314092T1 (de) 2006-01-15

Family

ID=22033995

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98949505T ATE314092T1 (de) 1997-09-26 1998-09-25 Biologische kleber und verfahren zur topischen verabreichung von wirkstoffen

Country Status (14)

Country Link
US (1) US6562363B1 (de)
EP (1) EP1021204B1 (de)
JP (1) JP2001517493A (de)
AT (1) ATE314092T1 (de)
AU (1) AU750809B2 (de)
CA (1) CA2304958C (de)
DE (1) DE69833000T2 (de)
DK (1) DK1021204T3 (de)
ES (1) ES2252865T3 (de)
IL (1) IL135258A0 (de)
NO (1) NO328846B1 (de)
NZ (1) NZ504108A (de)
RU (1) RU2234337C2 (de)
WO (1) WO1999015210A2 (de)

Families Citing this family (298)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022683B1 (en) 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
EP0965278A1 (de) * 1998-06-16 1999-12-22 Mathias Christian Zohoungbogbo Diätetisches Lebensmittel und diätetisches Verfahren unter Verwendung des Lebensmittels
ATE269063T1 (de) * 1998-07-24 2004-07-15 Alza Corp Formulierungen zur transdermalen verabreichung von fenoldopam
US6699497B1 (en) 1998-07-24 2004-03-02 Alza Corporation Formulations for the transdermal administration of fenoldopam
ATE447398T1 (de) 1998-12-18 2009-11-15 Alza Corp Durchsichtige transdermale nicotinabgabevorrichtungen
US20030170195A1 (en) * 2000-01-10 2003-09-11 Noven Pharmaceuticals, Inc. Compositions and methods for drug delivery
AU3470600A (en) * 1999-01-14 2000-08-01 David Houze Compositions and methods for drug delivery
ATE487491T1 (de) 1999-02-19 2010-11-15 Takeda Pharmaceutical Präparationen zur perkutanen aufnahme von zusammnesetzungen die einen angiotensin-ii- rezeptorantagonismus aufweisen
WO2000076478A1 (en) 1999-06-14 2000-12-21 Cosmo S.P.A. Controlled release and taste masking oral pharmaceutical compositions
US8895064B2 (en) 1999-06-14 2014-11-25 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
US7592304B2 (en) 1999-10-01 2009-09-22 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
US20030158111A1 (en) * 1999-10-01 2003-08-21 David Bar-Or Methods and products for oral care
US7632803B2 (en) 1999-10-01 2009-12-15 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
US6383511B1 (en) 1999-10-25 2002-05-07 Epicept Corporation Local prevention or amelioration of pain from surgically closed wounds
US6337076B1 (en) * 1999-11-17 2002-01-08 Sg Licensing Corporation Method and composition for the treatment of scars
DE19960154A1 (de) * 1999-12-14 2001-07-12 Lohmann Therapie Syst Lts Flache Arzneizubereitung zur transmucosalen Verabreichung von Oxycodon oder einem vergleichbaren Wirkstoff in der Mundhöhle, für die Anwendung in der Schmerztherapie und Suchttherapie
WO2001047559A1 (fr) * 1999-12-27 2001-07-05 Teikoku Seiyaku Co., Ltd Pastilles a usage externe
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US20030124177A1 (en) * 2000-04-26 2003-07-03 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
KR100338327B1 (ko) * 2000-05-16 2002-08-07 주식회사 태평양 피부 외용제 내의 활성성분의 피부 흡수를 증진시킬 수있는 조성물
KR100452972B1 (ko) * 2000-05-16 2004-10-14 주식회사 삼양사 경피투여용 하이드로젤 조성물
DE10025970C2 (de) * 2000-05-25 2002-04-25 Lohmann Therapie Syst Lts Estrogenhaltiges Pflaster mit einem Wirkstoffreservoir auf der Basis von Ethylcellulose und einem Ethylen-Vinylacetat-Vinylpyrrolidon-Copolymer und seine Verwendung
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
DE10033853A1 (de) * 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
EP1307182B1 (de) * 2000-08-01 2005-03-30 Sanofi-Aventis Pharmazeutische zusammensetzung zur verabreichung von beflotaxone
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
JPWO2002032431A1 (ja) * 2000-10-16 2004-02-26 久光製薬株式会社 外用剤組成物
US20030045539A1 (en) * 2000-11-06 2003-03-06 Baltazar Gomez-Mancilla Cabergoline and pramipexole: new uses and combinations
JP3962684B2 (ja) * 2000-11-06 2007-08-22 サムヤン コーポレイション 改善された水分吸収能および接着性を有する経皮投与剤
US7803392B2 (en) * 2000-12-27 2010-09-28 University Of Kentucky Research Foundation pH-Sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules
WO2002082907A1 (en) * 2001-01-12 2002-10-24 Board Of Regents, The University Of Texas System Novel antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces
US7494669B2 (en) * 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
US20050113510A1 (en) * 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US8840918B2 (en) * 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US8206738B2 (en) * 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US20050215727A1 (en) * 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
ATE438418T1 (de) 2001-05-01 2009-08-15 Av Topchiev Inst Petrochemical Hydrogel-zusammensetzungen
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
AU2002316053A1 (en) * 2001-05-01 2002-11-11 A.V. Topchiev Institute Of Petrochemical Synthesis Two-phase, water-absorbent bioadhesive composition
WO2002094179A2 (en) * 2001-05-23 2002-11-28 J.B. Chemicals & Pharmaceuticals Ltd. Novel topical microbicidal compositions
EP1262172A1 (de) * 2001-05-25 2002-12-04 Italmed S.N.C. Di Galli G. & Pacini G. Flüssige Polymerzusammensetzung zur Vorbeugung und Behandlung von Krankheiten der Mundhöhle
DE60236084D1 (de) * 2001-05-31 2010-06-02 Hisamitsu Pharmaceutical Co Perkutan resorbierbare pflaster
JP4943597B2 (ja) * 2001-07-31 2012-05-30 川澄化学工業株式会社 抗血栓性医療用具
US20030114394A1 (en) * 2001-10-29 2003-06-19 Levine Howard L. Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US8425892B2 (en) 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
US20050176746A1 (en) * 2002-05-17 2005-08-11 Frank Weber Use of compounds that are effective as selective opiate receptor modulators
DE10226494A1 (de) * 2002-06-14 2004-01-08 Lts Lohmann Therapie-Systeme Ag Filmförmige mucoadhäsive Darreichungsformen zur Verabreichung von Cannabis-Wirkstoffen
WO2004018741A1 (en) * 2002-08-23 2004-03-04 University Of Maryland Biotechnology Institute Assembly of chitosan onto an electrode surface
US20050100515A1 (en) * 2002-09-11 2005-05-12 The Procter & Gamble Company Tooth whitening products
AU2003275289A1 (en) * 2002-09-26 2004-04-19 University Of Maryland Baltimore County Polysaccharide-based polymers and methods of making the same
US7166641B2 (en) * 2002-10-02 2007-01-23 Yung Shin Pharmaceutical Industrial Co., Ltd. Pharmaceutically acceptable salts containing local anesthetic and anti-inflammatory activities and methods for preparing the same
ITMI20022271A1 (it) * 2002-10-25 2004-04-26 Farmaka Srl Composizioni farmaceutiche bioadesive a base di anitiinfiammatori non steroidei.
EP1560566B1 (de) * 2002-11-05 2012-04-11 Fadim S.r.l. Kontrollierte und kontinuierliche verabreichung von rifaximin
US8250698B2 (en) * 2002-11-09 2012-08-28 Gavney Jr James A Hybrid cleaning device including absorbent and contact elements
US7790010B2 (en) * 2002-12-20 2010-09-07 University Of Maryland, College Park Spatially selective deposition of polysaccharide layer onto patterned template
US7883615B2 (en) * 2003-02-12 2011-02-08 University Of Maryland, College Park Controlled electrochemical deposition of polysaccharide films and hydrogels, and materials formed therefrom
MXPA05010692A (es) * 2003-04-04 2006-04-18 Tissuemed Ltd Formulaciones que se adhieren a tejido.
AU2004238285A1 (en) * 2003-05-07 2004-11-25 Dmi Biosciences, Inc Oral care methods and products
EP1644004A4 (de) * 2003-06-20 2010-10-06 Ronald Aung-Din Topische therapie zur behandlung von migräne, muskelzerrungen, muskelspasmus, spastizität und verwandten zuständen
US7250475B2 (en) * 2003-06-26 2007-07-31 Symyx Technologies, Inc. Synthesis of photoresist polymers
DE10334188B4 (de) 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
ES2318330T3 (es) * 2003-08-08 2009-05-01 Elan Pharma International Limited Nuevas composiciones de metaxalona.
US7396819B2 (en) * 2003-08-08 2008-07-08 Virbac Corporation Anthelmintic formulations
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
WO2005025549A2 (en) * 2003-09-10 2005-03-24 Noven Pharmaceuticals, Inc. Multi-layer transdermal drug delivery device
TW200512013A (en) * 2003-09-18 2005-04-01 Orient Europharma Co Ltd Gel formulation of oxybutynin hydrochloride
WO2005027864A1 (en) * 2003-09-19 2005-03-31 Symyx Technologies, Inc. Materials for enhanced delivery of hydrophilic active agents in personal care formulations
ES2626784T3 (es) * 2003-10-28 2017-07-26 Noven Pharmaceuticals, Inc. Dispositivo de administración transdérmica de fármacos
DE10352602A1 (de) * 2003-11-11 2005-06-02 Rovi Gmbh & Co. Kosmetische Rohstoffe Kg Kosmetisches oder therapeutisches Kombinationspräparat
US20100330143A1 (en) 2003-12-04 2010-12-30 University Of Utah Research Foundation Modified macromolecules and methods of making and using thereof
EP1694712A1 (de) 2003-12-04 2006-08-30 University of Utah Research Foundation Modifizierte makromoleküle und verfahren zu ihrer herstellung und verwendung
US7375404B2 (en) * 2003-12-05 2008-05-20 University Of Maryland Biotechnology Institute Fabrication and integration of polymeric bioMEMS
US20050127552A1 (en) * 2003-12-11 2005-06-16 Kimberly-Clark Worldwide, Inc. Method for forming an elastomeric article
US20050132466A1 (en) * 2003-12-11 2005-06-23 Kimberly-Clark Worldwide, Inc. Elastomeric glove coating
FR2863502B1 (fr) * 2003-12-15 2007-03-16 Cousin Biotech Implant textile adhesif de refection parietale
SI1548845T1 (sl) * 2003-12-22 2007-06-30 Scheuten Glasgroep Bv postopek za obdelavo prašnih zrn
CA2552911A1 (en) * 2004-01-20 2005-08-11 Board Of Regents, The University Of Texas System Methods for coating and impregnating medical devices with antiseptic compositions
KR20070007299A (ko) 2004-01-30 2007-01-15 코리움 인터네셔널, 인크. 활성제의 전달을 위한 급속 용해 필름
IL160936A0 (en) * 2004-02-05 2004-08-31 Scott A Cordray Nasal spray and wash
US20070269519A1 (en) * 2004-03-03 2007-11-22 Constantine Georgiades Whitening products
US20050196348A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Stabilized peroxide compositions
US20050196355A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Film products having controlled disintegration properties
US20080003248A1 (en) * 2004-03-03 2008-01-03 Constantine Georgiades Whitening products
US20050196354A1 (en) * 2004-03-03 2005-09-08 Andre Soshinsky Film compositions
US20070190125A1 (en) * 2004-03-03 2007-08-16 Constantine Georgiades Positioning feature for aiding use of film or strip product
WO2005094210A2 (en) * 2004-03-12 2005-10-13 The Hartz Mountain Corporation Multi-action anthelmintic formulations
US20050244486A1 (en) * 2004-04-29 2005-11-03 Caldwell Larry J Topical methadone compositions and methods for using the same
US20070189980A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Compositions and methods for treating alopecia
US20070196452A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Flux-enabling compositions and methods for dermal delivery of drugs
US20080019927A1 (en) * 2004-06-07 2008-01-24 Jie Zhang Compositions and methods for dermally treating neuropathy with minoxidil
US8741333B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
US8907153B2 (en) 2004-06-07 2014-12-09 Nuvo Research Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
US20070196457A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs
US20070196323A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Polyvinyl alcohol-containing compositions and methods for dermal delivery of drugs
US20070189978A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Compositions and methods for dermally treating musculoskeletal pain
US20070196453A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more non-volatile solvent-containing compositions and methods for dermal delivery of drugs
US20070196293A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for treating photo damaged skin
US20070190124A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs
US20070189977A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Spray-on formulations and methods for dermal delivery of drugs
US20070196325A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for dermally treating infections
US8741332B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for dermally treating neuropathic pain
US8158139B2 (en) * 2004-07-12 2012-04-17 Taro Pharmaceuticals North America, Inc. Topical gel formulation comprising organophosphate insecticide and preparation thereof
WO2006017263A1 (en) * 2004-07-12 2006-02-16 Taro Pharmaceutical Industries Ltd. Topical gel formulation comprising organophosphate insecticide and its preparation thereof
GB0416861D0 (en) * 2004-07-29 2004-09-01 Quadrant Drug Delivery Ltd Composition
ES2344911T3 (es) 2004-08-02 2010-09-09 Glaxo Group Limited Composicion novedosa para tratar la xerostomia.
BRPI0514106A (pt) * 2004-08-03 2008-05-27 Tissuemed Ltd materiais adesivos a tecidos
MX2007001512A (es) * 2004-08-05 2007-04-20 Corium Int Inc Composicion adhesiva.
WO2006028863A1 (en) * 2004-09-01 2006-03-16 Nexmed Holdings, Inc. Transdermal antiemesis delivery system, method and composition therefor
RU2272626C1 (ru) * 2004-09-06 2006-03-27 Открытое акционерное общество "Щелковский витаминный завод" Антипротозойное средство на основе метронидазола
RU2277933C2 (ru) * 2004-09-21 2006-06-20 Государственное образовательное учреждение высшего профессионального образования Курский государственный медицинский университет Министерства здравоохранения Российской Федерации Иммобилизованная форма цефазолина для профилактики послеоперационных инфекционных осложнений в оториноларингологии
WO2006041908A2 (en) * 2004-10-08 2006-04-20 Noven Pharmaceuticals, Inc. Transdermal delivery of estradiol
US20060078602A1 (en) 2004-10-08 2006-04-13 Noven Pharmaceuticals, Inc. Device for transdermal administration of drugs including acrylic polymers
WO2006041907A2 (en) 2004-10-08 2006-04-20 Noven Pharmaceuticals, Inc. Transdermal delivery of estradiol
ES2596809T3 (es) * 2004-10-08 2017-01-12 Noven Pharmaceuticals, Inc. Dispositivo de administración transdérmica de fármacos que incluye un refuerzo oclusivo
RU2260432C1 (ru) * 2004-10-12 2005-09-20 Открытое Акционерное Общество "Нижегородский Химико-Фармацевтический Завод" (Оао "Нижфарм") Средство для лечения болезней суставов
EP1923059A1 (de) * 2004-11-04 2008-05-21 BIOFARMITALIA S.p.A. Pflaster mit einer aus Teer selektierten Substanz mit reduzierenden Eigenschaften in der Dermatologie
ITMI20042111A1 (it) * 2004-11-04 2005-02-04 Biofarmitalia Spa Cerotto contenenti una sostanza scelta tra i catrami aventi caratteristiche riducenti in dermatologia
FI20041425A0 (fi) * 2004-11-05 2004-11-05 Orion Corp Transmukosaalinen veterinäärinen koostumus
US20060106117A1 (en) * 2004-11-12 2006-05-18 Kimberly-Clark Worldwide, Inc. Compound and method for prevention and/or treatment of vaginal infections
US7619008B2 (en) * 2004-11-12 2009-11-17 Kimberly-Clark Worldwide, Inc. Xylitol for treatment of vaginal infections
US8569367B2 (en) * 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
US7582330B2 (en) * 2004-11-24 2009-09-01 3M Innovative Properties Counsel Method for making metallic nanostructures
US20060110540A1 (en) * 2004-11-24 2006-05-25 3M Innovative Properties Company Method for making nanostructured surfaces
US7687115B2 (en) * 2004-11-24 2010-03-30 3M Innovative Properties Company Method for making nanostructured surfaces
US7766658B2 (en) * 2004-11-30 2010-08-03 Align Technology, Inc. Systems and methods for intra-oral diagnosis
US20060115785A1 (en) * 2004-11-30 2006-06-01 Chunhua Li Systems and methods for intra-oral drug delivery
US7947508B2 (en) * 2004-11-30 2011-05-24 Align Technology, Inc. Systems and methods for intra-oral diagnosis
US20060115782A1 (en) * 2004-11-30 2006-06-01 Chunhua Li Systems and methods for coating a dental appliance
MX2007006833A (es) 2004-12-10 2007-10-08 Talima Therapeutics Inc Composiciones y metodos para tratar condiciones de la unidad de una.
US20060275230A1 (en) 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
RU2277411C1 (ru) * 2004-12-15 2006-06-10 Ольга Алексеевна Кост Фармацевтическая композиция для лечения глазных болезней, связанных с нарушением микроциркуляции и/или воспалительными процессами
US8080560B2 (en) * 2004-12-17 2011-12-20 3M Innovative Properties Company Immune response modifier formulations containing oleic acid and methods
FR2879931B1 (fr) * 2004-12-24 2007-03-30 Rhodia Chimie Sa Materiau silicone pour la liberation d'une molecule active
RU2282443C1 (ru) * 2004-12-29 2006-08-27 Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" Лекарственное средство, обладающее антигипертензивным действием, и способ его изготовления
US20060213815A1 (en) * 2005-01-28 2006-09-28 Wille John J Hydrocarbon fume suppression by higher vapor pressure temperature oils
RU2283089C1 (ru) * 2005-03-03 2006-09-10 Общество с ограниченной ответственностью "Фарм-Лад" Мазь для наружного применения
PT1863469E (pt) 2005-03-15 2012-03-22 Animal Ethics Pty Ltd Composição anestésica tópica
RU2357753C1 (ru) * 2005-03-24 2009-06-10 Владимир Николаевич Филатов Материал, обладающий биологической активностью, способ его получения и терапевтическое средство на его основе
US20060223765A1 (en) * 2005-03-30 2006-10-05 Kimberly-Clark Worldwide, Inc. Method for inhibiting and/or treating vaginal infection
AP2244A (en) * 2005-04-26 2011-06-24 Caldwell Galer Inc Topical methadone compositions and methods for using the same.
ATE415153T1 (de) * 2005-06-06 2008-12-15 Nitto Denko Corp Pharmazeutische zusammensetzung zur perkutane absorption unter verwendung von einem metalchlorid, vorzugsweise natriumchlorid, zur vorbeugung von kohäsionsschwäche
ITBO20050388A1 (it) * 2005-06-06 2006-12-07 Alfa Wassermann Spa Formulazione mucoadesive utili in dispositivi medici in preparazioni farmaceutiche
WO2006133349A2 (en) * 2005-06-08 2006-12-14 Alpharma, Inc. Orally disintegrable sleep aid formulations
EP1888025B1 (de) * 2005-06-08 2020-08-12 Basf Corporation Medikamententrägerzusammensetzung und verfahren zur bildung eines films daraus
US7560445B2 (en) * 2005-07-06 2009-07-14 Taro Pharmaceuticals North America, Inc. Process for preparing malathion for pharmaceutical use
AU2005334836B2 (en) * 2005-07-28 2012-04-12 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Sensitization of immune system against haptenized melanoma antigens
US7786176B2 (en) 2005-07-29 2010-08-31 Kimberly-Clark Worldwide, Inc. Vaginal treatment composition containing xylitol
JP5058531B2 (ja) * 2005-09-09 2012-10-24 日東電工株式会社 ビソプロロール含有貼付製剤
US7629027B2 (en) 2005-10-14 2009-12-08 3M Innovative Properties Company Method for making chromonic nanoparticles
US7718716B2 (en) * 2005-10-14 2010-05-18 3M Innovative Properties Company Chromonic nanoparticles containing bioactive compounds
US20070092454A1 (en) * 2005-10-24 2007-04-26 Colgate-Palmolive Company Oral composition containing morin
US8119162B2 (en) 2005-11-10 2012-02-21 Colgate-Palmolive Company Particles that disrupt or impede bacterial adhesion, related compositions and methods
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US7807661B2 (en) * 2005-12-08 2010-10-05 3M Innovative Properties Company Silver ion releasing articles and methods of manufacture
WO2007065303A1 (en) * 2005-12-09 2007-06-14 Beijing Kangbeide Pharmaceutical Technology Development Co., Ltd. Transdermal patch containing isosorbide dinitrate and bisoprolol
US9522188B2 (en) 2005-12-13 2016-12-20 Biodelivery Sciences International, Inc. Abuse resistant transmucosal drug delivery device
EP1959930A2 (de) * 2005-12-14 2008-08-27 Zars, Inc. Zusammensetzungen zur flussauslösung und verfahren zur dermalen verabreichung von wirkstoffen
CN101494976B (zh) * 2005-12-14 2013-12-18 努沃研究公司 用于经皮肤治疗痛的组合物和方法
CN101370453B (zh) * 2005-12-14 2013-12-18 努沃研究公司 用于皮肤输送药物的组合物和方法
CA2633515C (en) * 2005-12-14 2011-10-18 Jie Zhang Compositions and methods for dermally treating pain
US7601769B2 (en) * 2005-12-19 2009-10-13 3M Innovative Peroperties Company Multilayered chromonic structures
US8092710B2 (en) * 2005-12-19 2012-01-10 3M Innovative Properties Company Hierarchical chromonic structures
US7541052B1 (en) * 2005-12-23 2009-06-02 Scott Cordray Hypertonic solutions and method of treatment
US7824732B2 (en) * 2005-12-28 2010-11-02 3M Innovative Properties Company Encapsulated chromonic particles
US20070166244A1 (en) * 2006-01-19 2007-07-19 The Procter & Gamble Company Compositions comprising silicone pressure sensitive adhesives for delivering oral care substances
US8399012B2 (en) 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
US20070280972A1 (en) * 2006-04-25 2007-12-06 Zars, Inc. Adhesive solid gel-forming formulations for dermal drug delivery
US20070258935A1 (en) * 2006-05-08 2007-11-08 Mcentire Edward Enns Water dispersible films for delivery of active agents to the epidermis
US20070259029A1 (en) * 2006-05-08 2007-11-08 Mcentire Edward Enns Water-dispersible patch containing an active agent for dermal delivery
US8703179B2 (en) * 2006-05-11 2014-04-22 Kimberly-Clark Worldwide, Inc. Mucosal formulation
RU2308966C1 (ru) * 2006-05-18 2007-10-27 Институт физиологически активных веществ Российской Академии Наук (ИФАВ РАН) Антиметастатическая композиция
NZ573174A (en) * 2006-06-01 2012-01-12 Msd Consumer Care Inc Sustained release pharmaceutical dosage form containing phenylephrine
CA2653953C (en) * 2006-06-01 2015-12-08 Schering-Plough Healthcare Products, Inc. Phenylephrine pharmaceutical formulations and compositions for colonic absorption
CN101472561A (zh) * 2006-06-01 2009-07-01 先灵公司 去氧肾上腺素脉冲释放制剂和药物组合物
MX2008015358A (es) * 2006-06-01 2009-03-06 Schering Corp Composiciones farmaceuticas para liberacion sostenida de fenilefrina.
TWI392670B (zh) * 2006-06-22 2013-04-11 Ucb Pharma Gmbh 經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途
US7635415B2 (en) 2006-06-29 2009-12-22 The Clorox Company Regenerable cleaning implement for sanitizing a surface
ES2577390T3 (es) 2006-07-21 2016-07-14 Biodelivery Sciences International, Inc. Dispositivos de administración transmucosa con mayor captación
RU2317810C1 (ru) * 2006-07-27 2008-02-27 Открытое Акционерное Общество "Татхимфармпрепараты" Состав и способ получения глазной мази ципрофлоксацина
EP1891946A1 (de) * 2006-08-14 2008-02-27 Santhera Pharmaceuticals (Schweiz) AG Transmukosale Verabreichung von 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinon
US20080057090A1 (en) * 2006-09-01 2008-03-06 Mcentire Edward Enns Wrinkle masking film composition for skin
US7879942B2 (en) * 2006-10-05 2011-02-01 Eastman Chemical Company Switchable adhesive article for attachment to skin and method of using the same
MX2009004358A (es) * 2006-10-27 2009-06-17 Noven Pharma Suministro transdermico de derivados polares de cetoprofeno.
US7829116B2 (en) * 2006-11-14 2010-11-09 Momentive Performance Materials Inc. Adhesive-forming composition and blend of adhesives obtained therefrom
US7976951B2 (en) 2006-11-14 2011-07-12 Momentive Performance Materials Inc. Laminate containing an adhesive-forming composition
RU2322232C1 (ru) * 2006-12-04 2008-04-20 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) Композиция для приготовления противотромбозного геля
JP2008163017A (ja) * 2006-12-06 2008-07-17 Saitama Daiichi Seiyaku Kk 外用医薬組成物及び貼付剤
US20100136082A1 (en) 2006-12-22 2010-06-03 Laboratoire Medidom S.A. In situ system for intra-articular chondral and osseous tissue repair
KR101612901B1 (ko) * 2007-03-02 2016-04-15 테이카 세이야쿠 가부시키가이샤 경피흡수 의약조성물, 의약조성물 저장유닛 및 이것을 이용하는 경피흡수제제
CN101677997B (zh) 2007-03-30 2012-05-09 泰奥加制药公司 用于治疗腹泻型和交替型肠易激综合征的κ-阿片剂激动剂
CA2697959A1 (en) * 2007-06-01 2008-12-11 Schering-Plough Healthcare Products, Inc. Pharmaceutical composition comprising a substrate and a coating containing an active ingredient and polyvinylalcohol
US20080300322A1 (en) * 2007-06-01 2008-12-04 Atlantic Pharmaceuticals, Inc. Delivery vehicles containing rosin resins
ITRM20070510A1 (it) * 2007-10-02 2009-04-03 Rmfa Trading S A Composizioni oftalmiche a base di polisaccaride del seme di tamarindo e acido ialuronico.
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
DK3354276T3 (da) * 2007-11-13 2020-03-30 Meritage Pharma Inc Sammensætninger til behandlingen af gastrointestinal inflammation
US20090143343A1 (en) * 2007-11-13 2009-06-04 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
PE20091084A1 (es) * 2007-12-07 2009-07-23 Schering Plough Healthcare Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal
US9314524B2 (en) * 2007-12-31 2016-04-19 Calla Therapeutics Llc Topical formulations of Flucytosine
US20090221615A1 (en) * 2008-02-29 2009-09-03 Guru Reddy Combination anti-cancer agents
RU2376016C1 (ru) * 2008-03-04 2009-12-20 Мария Станиславовна Коллерова Средство для лечения воспалительных заболеваний пародонта
WO2009118589A2 (en) 2008-03-24 2009-10-01 Wockhardt Research Centre Orally disintegrating compositions of rhein or diacerein
US9072727B2 (en) * 2008-04-18 2015-07-07 Warsaw Orthopedic, Inc. Alpha adrenergic receptor agonists for treatment of degenerative disc disease
US11969501B2 (en) 2008-04-21 2024-04-30 Dompé Farmaceutici S.P.A. Auris formulations for treating otic diseases and conditions
WO2009132050A2 (en) 2008-04-21 2009-10-29 Otonomy, Inc. Auris formulations for treating otic diseases and conditions
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
US20090269403A1 (en) * 2008-04-24 2009-10-29 Shaked Ze Ev Oral contraceptive dosage forms and methods of making such dosage forms
WO2009133128A1 (en) * 2008-04-29 2009-11-05 Pharnext Combination compositions for treating alzheimer disease and related disorders with zonisamide and acamprosate
US8729108B2 (en) * 2008-06-17 2014-05-20 Christopher J Dannaker Waterborne topical compositions for the delivery of active ingredients such as azelaic acid
CN105833420A (zh) * 2008-06-23 2016-08-10 生物递送科学国际公司 多向粘膜给药装置及使用方法
EP2317975B1 (de) * 2008-06-25 2016-04-13 Endo Pharmaceuticals Solutions Inc. Octreotid-implantat mit freisetzungsmittel
US8231906B2 (en) * 2008-07-10 2012-07-31 Noven Pharmaceuticals, Inc. Transdermal estrogen device and delivery
US8784870B2 (en) 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
WO2010011605A2 (en) 2008-07-21 2010-01-28 Otonomy, Inc. Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders
AU2009281998A1 (en) * 2008-08-12 2010-02-18 Novabay Pharmaceuticals, Inc. Antimicrobial gel formulations
EP2328553B1 (de) 2008-08-20 2020-06-10 The Regents of The University of California Kortikosteroide zur behandlung von entzündlichen erkrankungen des magen-darm-trakts
CA2735418A1 (en) * 2008-08-26 2010-03-11 Ray L. Hauser Substance delivery to skin and other tissues
US20100120776A1 (en) * 2008-11-12 2010-05-13 Hall Bioscience Corporation Carbocysteine medical foods
US8945592B2 (en) * 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
WO2010083035A2 (en) 2009-01-14 2010-07-22 Corium International, Inc. Transdermal administration of tamsulosin
WO2010088697A2 (en) * 2009-02-02 2010-08-05 Medtronic, Inc. Antimicrobial accessory for an implantable medical device
US8858983B2 (en) * 2009-04-30 2014-10-14 Medtronic, Inc. Antioxidants and antimicrobial accessories including antioxidants
US8920392B2 (en) 2009-05-05 2014-12-30 Watson Laboratories, Inc. Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions
EP2440210A4 (de) * 2009-06-12 2014-01-29 Meritage Pharma Inc Verfahren zur behandlung von magen-darm-erkrankungen
US20090318568A1 (en) * 2009-08-26 2009-12-24 Hauser Ray L Adherent coating for tissue surface and/or trans-tissue surface substance delivery
MX2012003986A (es) * 2009-10-05 2012-06-25 Yissum Res Dev Co Composiciones liquidas presursoras y usos de las mismas para un tratamiento de liberacion sostenida en ph-dependiente de los trastornos orales.
WO2011056561A1 (en) 2009-10-27 2011-05-12 Beth Israel Deaconess Medical Center Methods and compositions for the generation and use of conformation-specific antibodies
RU2432964C2 (ru) * 2009-11-26 2011-11-10 Государственное образовательное учреждение высшего профессионального образования Кабардино-Балкарский государственный университет им. Х.М. Бербекова (КБГУ) Полимерная целлюлозная композиция и способ ее получения
RU2416394C1 (ru) * 2010-01-25 2011-04-20 Пшеничников Виталий Георгиевич Фармацевтическая композиция в виде спрея для лечения раневых поверхностей
RU2627588C2 (ru) 2010-03-08 2017-08-09 Спектрум Фармасьютикалз, Инк. Способы лечения рака с применением ингибитора аутофагии на основе тиоксантона
MX350636B (es) 2010-03-26 2017-09-12 Philip Morris Products Sa Inhibicion de irritacion sensorial durante el consumo de productos de tabaco no fumables.
US8952038B2 (en) 2010-03-26 2015-02-10 Philip Morris Usa Inc. Inhibition of undesired sensory effects by the compound camphor
US9572773B2 (en) * 2010-04-26 2017-02-21 Novartis A.G. Layered drug delivery device
JP5820469B2 (ja) 2010-04-30 2015-11-24 テイコク ファーマ ユーエスエー インコーポレーテッド プロピニルアミノインダンの経皮組成物
MX2012013955A (es) * 2010-06-23 2013-01-24 Colgate Palmolive Co Composiciones terapeuticas bucales.
US8287901B2 (en) * 2010-08-11 2012-10-16 Adhezion Biomedical, Llc Wound healing compositions based on cyanoacrylates and 5,5-disubstitutedhydantoins, including phenytoin
CA2817982C (en) 2010-11-15 2020-06-30 The Regents Of The University Of Michigan Controlled release mucoadhesive systems
US8911427B2 (en) * 2010-12-28 2014-12-16 Medtronic, Inc. Therapeutic agent reservoir delivery system
CN103429222B (zh) * 2011-03-07 2015-09-09 3M创新有限公司 微针装置和方法
EP2688561B1 (de) 2011-03-24 2018-08-22 Teikoku Pharma USA, Inc. Transdermale zusammensetzungen mit einer wirkstoffschicht und einer wirkstoffumwandlungsschicht
US10487114B2 (en) 2011-04-27 2019-11-26 Beth Israel Deaconess Medical Center, Inc. Methods for administering peptides for the generation of effective c/s conformation-specific antibodies to a human subject in need thereof
MX349572B (es) * 2011-05-10 2017-08-03 Itochu Chemical Frontier Corp Parche no acuoso.
ES3034911T3 (en) 2011-05-10 2025-08-26 Itochu Chemical Frontier Corp Non-aqueous patch
US11786455B2 (en) 2011-05-10 2023-10-17 Itochu Chemical Frontier Corporation Non-aqueous patch
WO2012176668A1 (ja) * 2011-06-20 2012-12-27 久光製薬株式会社 リドカイン含有パップ剤
US10865383B2 (en) 2011-07-12 2020-12-15 Lineage Cell Therapeutics, Inc. Methods and formulations for orthopedic cell therapy
MX352959B (es) 2011-08-18 2017-12-15 Biodelivery Sciences Int Inc Dispositivos mucoadhesivos resistentes al abuso para el suministro de buprenorfina.
US10154964B2 (en) 2011-09-07 2018-12-18 Cosmo Technologies Limited Controlled release and taste masking oral pharmaceutical composition
US10765640B2 (en) 2011-09-27 2020-09-08 Itochu Chemical Frontier Corporation Non-aqueous patch
EP2776020B1 (de) 2011-11-09 2019-09-11 Teikoku Seiyaku Co., Ltd. Verfahren zur behandlung von neoplasmen der haut
EP2594132A1 (de) * 2011-11-16 2013-05-22 Lanxess Deutschland GmbH Stabilisierung von Iod enthaltenden Verbindungen mit Stickstoff enthaltenden Polymeren
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
US9789061B2 (en) * 2012-02-19 2017-10-17 Orahealth Corp. Acacia gum adhesive with calcium carbonate for oral adhering discs
RU2493877C1 (ru) * 2012-10-19 2013-09-27 Закрытое акционерное общество "ФИРН М" (ЗАО "ФИРН М") Ранозаживляющее медицинское средство для лечения ран и ожогов с терапевтическим эффектом
RU2492873C1 (ru) * 2012-10-19 2013-09-20 Закрытое акционерное общество "ФИРН М" (ЗАО "ФИРН М") Сорбционный материал для лечения ран и ожогов различной этиологии
JP6050896B2 (ja) 2012-11-02 2016-12-21 テイコク ファーマ ユーエスエー インコーポレーテッド プロピニルアミノインダン経皮組成物
JP6893086B2 (ja) 2013-03-13 2021-06-23 エーブリー デニソン コーポレイション 接着特性の向上
US11337936B2 (en) 2013-03-14 2022-05-24 Noven Pharmaceuticals, Inc. Amphetamine transdermal compositions with acrylic block copolymer
CN105377355A (zh) 2013-03-14 2016-03-02 拇趾公司 治疗甲单元的感染、疾病或病症的方法
KR101891185B1 (ko) * 2013-10-07 2018-08-24 테이코쿠 팔마 유에스에이, 인코포레이티드 비진정량의 덱스메데토미딘의 경피 전달을 위한 방법 및 조성물
RU2646512C2 (ru) 2013-10-07 2018-03-05 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Устройства для трансдермальной доставки дексмедетомидина и способы их применения
TWI709417B (zh) 2013-10-07 2020-11-11 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
RU2550916C1 (ru) * 2013-12-26 2015-05-20 Открытое Акционерное Общество "Татхимфармпрепараты" Фармацевтическая композиция для лечения заболеваний опорно-двигательного аппарата
FR3017533B1 (fr) * 2014-02-19 2016-03-11 Cousin Biotech Dispositif implantable, notamment pour la refection de paroi abdominale
RU2592370C9 (ru) * 2014-04-24 2016-08-27 Иван Иванович Дедов Средство на основе дегидроэпиандростерона, способ его применения
RU2560516C1 (ru) * 2014-07-21 2015-08-20 Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт фундаментальной и прикладной паразитологии животных и растений имени К.И. Скрябина" (ФГБНУ "ВНИИП им. К.И. Скрябина) Антигельминтное средство с трематодоцидной и цестодоцидной активностью
MX363010B (es) 2014-11-25 2019-03-04 Trophea Dev Ab Tratamiento de la atrofia de piel con una combinacion de acido triyodotiroacetico (triac) y dehidroepiandrosterona (dhea).
EP3328898B8 (de) 2015-07-28 2024-04-10 6452728 Canada Corp. Trkb- oder trkc-agonisten-zusammensetzungen und verfahren zur behandlung von erkrankungen des ohrs
CA3033570C (en) * 2015-08-17 2022-12-06 Sidmak Laboratories (India) Pvt. Ltd. Topical film delivery system
RU2677338C2 (ru) * 2015-10-06 2019-01-16 Общество с ограниченной ответственностью "Трейдсервис" Лекарственная форма диоксотетрагидрокситетрагидронафталина
EP3478269A4 (de) 2016-06-29 2020-04-08 Otonomy, Inc. Triclyceridformulierungen für das ohr und verwendungen davon
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
KR20180036580A (ko) * 2016-09-30 2018-04-09 주식회사 유스바이오팜 수가용화(水加溶化)된 우르소데옥시콜산을 함유하는 염증성 피부질환 또는 중증 소양증 예방 또는 치료용 조성물
KR20190060007A (ko) 2016-10-31 2019-05-31 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 전달 장치를 이용한 통증을 관리하는 방법
DE102017104026A1 (de) 2017-02-27 2018-08-30 Lts Lohmann Therapie-Systeme Ag Nicotin enthaltendes transparentes transdermales therapeutisches System
JP6748237B2 (ja) * 2017-08-01 2020-08-26 久光製薬株式会社 貼付剤
DE102017127433A1 (de) * 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag TTS auf Basis von klebenden Weichmacher-Polymer-Matrices
DE102017127452A1 (de) * 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag Wasserlösliche Polymerklebschichten
US20190192662A1 (en) 2017-12-22 2019-06-27 Noven Pharmaceuticals, Inc. Transdermal pharmaceutical compositions with reduced skin irritation
WO2019140012A1 (en) 2018-01-09 2019-07-18 Otonomy, Inc. Growth factor otic formulations
WO2019154895A1 (en) 2018-02-08 2019-08-15 Strekin Ag Gel formulation for preventing or treating hearing loss
US12144899B2 (en) * 2018-04-25 2024-11-19 Shinkei Therapeutics, Inc. Tetrabenazine transdermal delivery device
WO2020100096A1 (en) * 2018-11-15 2020-05-22 Glenmark Specialty S.A. Topical composition comprising mupirocin
ES2777899A1 (es) * 2019-02-06 2020-08-06 Hector Alfredo Duilio Polizzi Apósito oral con efecto anestésico
RU2770045C2 (ru) * 2020-04-16 2022-04-14 Андрей Анатольевич Сланевский Способ регенерации резины
CN111671737B (zh) * 2020-05-26 2022-07-08 浙江工业大学 一种地塞米松口腔速溶膜剂及其制备方法
US12491166B2 (en) 2020-08-31 2025-12-09 Wacker Chemie Ag Method of delivering an active compound and delivery device for use in the same
WO2022125405A1 (en) 2020-12-07 2022-06-16 O&M Halyard, Inc. Damp hand donning and moisturizing glove
RU2761303C1 (ru) * 2021-03-15 2021-12-07 Общество с ограниченной ответственностью "Дубна-Биофарм". Способ получения фармацевтической композиции и фармацевтическая композиция для лечения и профилактики заболеваний пародонта
CN113181418B (zh) * 2021-04-09 2022-05-03 青岛大学附属医院 一种医用粘合剂及其制备方法
CA3232272A1 (en) * 2021-10-15 2023-04-20 Hans-Werner Wolf Transdermal therapeutic system for the transdermal administration of tizanidine
US20250228769A1 (en) * 2022-03-11 2025-07-17 Lts Lohmann Therapie-Systeme Ag Oromucosal therapeutic system containing an adhesive layer
AU2023232910A1 (en) * 2022-03-11 2024-09-12 Lts Lohmann Therapie-Systeme Ag Transmucosal therapeutic system containing a macrolide immunosuppressant

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1050070A (de) * 1900-01-01
SE352239B (de) 1966-11-30 1972-12-27 Astra Pharma Prod
GB1430515A (en) 1973-09-04 1976-03-31 Hollister Inc Pharmaceutical preparations
GB2046773B (en) * 1979-03-21 1983-08-03 Advance Tapes Uk Ltd Gelatinous articles and compositions
DE2951319C2 (de) 1979-12-20 1983-12-22 Beiersdorf Ag, 2000 Hamburg Paste für medizinische Zwecke
JPS58213709A (ja) * 1982-06-05 1983-12-12 Teikoku Seiyaku Kk 歯肉粘膜用貼付剤
FR2532546B1 (fr) 1982-09-07 1985-12-27 Biotrol Sa Lab Pate pour la protection de la peau
US4740365A (en) * 1984-04-09 1988-04-26 Toyo Boseki Kabushiki Kaisha Sustained-release preparation applicable to mucous membrane in oral cavity
US4593053A (en) * 1984-12-07 1986-06-03 Medtronic, Inc. Hydrophilic pressure sensitive biomedical adhesive composition
US4755396A (en) 1984-12-10 1988-07-05 Geisler Thomas C Image receiving element for thermal printers
US4751087A (en) 1985-04-19 1988-06-14 Riker Laboratories, Inc. Transdermal nitroglycerin delivery system
US4764378A (en) 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
USRE33093E (en) 1986-06-16 1989-10-17 Johnson & Johnson Consumer Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
JPH0794384B2 (ja) 1986-09-01 1995-10-11 帝国製薬株式会社 徐放性口腔内用製剤
JPS63160661A (ja) 1986-12-24 1988-07-04 テルモ株式会社 外用組成物
US5032207A (en) 1988-03-04 1991-07-16 Noven Pharmaceuticals, Inc. One-step method for forming a pressure-sensitive adhesive transdermal drug device
US5446070A (en) 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5234957A (en) * 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5047244A (en) * 1988-06-03 1991-09-10 Watson Laboratories, Inc. Mucoadhesive carrier for delivery of therapeutical agent
JP3115625B2 (ja) 1991-03-30 2000-12-11 帝國製薬株式会社 リドカイン含有外用貼付剤
US5346701A (en) * 1993-02-22 1994-09-13 Theratech, Inc. Transmucosal delivery of macromolecular drugs
US5700478A (en) * 1993-08-19 1997-12-23 Cygnus, Inc. Water-soluble pressure-sensitive mucoadhesive and devices provided therewith for emplacement in a mucosa-lined body cavity
IL116539A (en) * 1995-01-06 2002-02-10 Noven Pharma Preparations given through the skin of unstable anti-acid drugs
US6210699B1 (en) 1999-04-01 2001-04-03 Watson Pharmaceuticals, Inc. Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity

Also Published As

Publication number Publication date
RU2234337C2 (ru) 2004-08-20
EP1021204B1 (de) 2005-12-28
NO20001567D0 (no) 2000-03-24
NZ504108A (en) 2002-06-28
ES2252865T3 (es) 2006-05-16
AU750809B2 (en) 2002-07-25
NO328846B1 (no) 2010-05-31
CA2304958A1 (en) 1999-04-01
DE69833000D1 (de) 2006-02-02
US6562363B1 (en) 2003-05-13
WO1999015210A3 (en) 1999-06-17
AU9581398A (en) 1999-04-12
JP2001517493A (ja) 2001-10-09
WO1999015210A2 (en) 1999-04-01
WO1999015210B1 (en) 1999-08-19
CA2304958C (en) 2008-12-30
DE69833000T2 (de) 2006-09-07
IL135258A0 (en) 2001-05-20
EP1021204A2 (de) 2000-07-26
DK1021204T3 (da) 2006-05-08
NO20001567L (no) 2000-05-25

Similar Documents

Publication Publication Date Title
DE69833000D1 (de) Biologische kleber und verfahren zur topischen verabreichung von wirkstoffen
ATE258426T1 (de) Zusammensetzungen und verfahren zur topischen anwendungen von wirkstoffen
DE69214938D1 (de) Mittel zur topischen verabreichung von arzneiwirkstoffen
DE69531104D1 (de) Transdermales system zur verabreichung durch entepithelisierte haut
DE69230772D1 (de) Arzneizubereitungen zur Behandlung von Onychomykosen
DK1299108T3 (da) Parasiticidt præparat samt fremgangsmåde til fremstilling af dette præparat
EP0857488A3 (de) Verfahren und Zusammensetzungen zur Erhöhung des Hautdurchtritts von Arzneistoffen unter Verwendung von Permeationsbeschleunigern
EP0857488A1 (de) Verfahren und Zusammensetzungen zur Erhöhung des Hautdurchtritts von Arzneistoffen unter Verwendung von Permeationsbeschleunigern
CY1114594T1 (el) Χρηση της [d-meala]3[etval]4-κυκλοσπορινης για την θεραπεια μολυνσης απο ηπατιτιδα c και φαρμακευτικη συνθεση που περιλαμβανει την εν λογω [d-meala]3[etval]4-κυκλοσπορινη
ES2133807T3 (es) Compuestos de peptidilo y su uso terapeutico como inhibidores de metaloproteasas.
NO962833L (no) Transdermalt preparat omfattende polyvinylpyrrolidin
ATE249422T1 (de) Verbindungen und zusammensetzungen zur verabreichung aktiver stoffe
DK0839026T3 (da) Micellære polyether-blokcopolymerkompositioner til målretning af biologiske midler
DK0969843T3 (da) Antitussive formuleringer indeholdende theobromin
DK1450771T3 (da) Farmaceutiske præparater til behandling af hudlæsioner og slimhinder og fremgangsmåder og kits til anvendelse heraf
YU16399A (sh) ) UPOTREBA INHIBITOR H +, K+ - ATP- aze I FARMACEUTSKA FORMULACIJA ZA SIMULTANU, SEPARATNU ILI SEKVENCIJALNU UPOTREBU, KOJA SADRZI INHIBITOR H +, K+-ATP- aze I GLUKOKORTIKOID INHIBITOR H +, K+- ATP- aze
EP1023901A4 (de) Heilmittel für hepatitis c und dessen verwendung
SE9602644D0 (sv) New use
EP1240899A3 (de) Regulierung der TH1/TH2 Cytokinexpression durch Ribavirin and Ribavirinanaloge in activierten T-Lymphocyten, zur Behandlung der HCV-Infektionen
BR0014751A (pt) Composto, estereoisÈmero ou mistura de estereoisÈmeros, composição farmacêutica, método de tratamento de um paciente em necessidade de tratamento antimicrobiano, e, uso de um composto
ES2191825T3 (es) Sales metalicas de acidos biliares con accion fisiologica y su uso en terapia.
ATE212222T1 (de) Zusammensetzungen zur transdermalen und dermalen verabreichung von biologisch wirksamen stoffen
PT1313500E (pt) Associacoes de dalfopristina/quinupristina com o cefpirome

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1021204

Country of ref document: EP

RZN Patent revoked