BRPI0515748A - proteìna recombinante produzida por bactérias gram-positivas, método para fabricá-la, para isolar ìons de metal de um lìquido, para converter um substrato em um produto, seu uso e respectivo kit - Google Patents
proteìna recombinante produzida por bactérias gram-positivas, método para fabricá-la, para isolar ìons de metal de um lìquido, para converter um substrato em um produto, seu uso e respectivo kitInfo
- Publication number
- BRPI0515748A BRPI0515748A BRPI0515748-0A BRPI0515748A BRPI0515748A BR PI0515748 A BRPI0515748 A BR PI0515748A BR PI0515748 A BRPI0515748 A BR PI0515748A BR PI0515748 A BRPI0515748 A BR PI0515748A
- Authority
- BR
- Brazil
- Prior art keywords
- fbfp
- gram
- metal ions
- liquid
- useful
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000007788 liquid Substances 0.000 title abstract 2
- 229910021645 metal ion Inorganic materials 0.000 title abstract 2
- 241000192125 Firmicutes Species 0.000 title 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000758 substrate Substances 0.000 title 1
- 230000001580 bacterial effect Effects 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 241000006382 Bacillus halodurans Species 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 108010040721 Flagellin Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000002018 overexpression Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2101/00—Nature of the contaminant
- C02F2101/10—Inorganic compounds
- C02F2101/20—Heavy metals or heavy metal compounds
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F3/00—Biological treatment of water, waste water, or sewage
- C02F3/34—Biological treatment of water, waste water, or sewage characterised by the microorganisms used
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- AIDS & HIV (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
- Water Treatment By Sorption (AREA)
Abstract
"PROTEìNA RECOMBINANTE PRODUZIDA POR BACTéRIAS GRAM-POSITIVAS, MéTODO PARA FABRICá-LA, PARA ISOLAR ìONS DE METAL DE UM LìQUIDO, PARA CONVERTER UM SUBSTRATO EM UM PRODUTO, SEU USO E RESPECTIVO KIT". A invenção refere-se a proteínas de fusão baseadas em flagelina (FBFP) úteis para uma variedade de propósitos, os ácidos nucléicos que codificam as FBFP, vetores que contêm os ácidos nucléicos células hospedeiras que abrigam os vetores. Ademais, a invenção proporciona métodos para obter superexpressão e exibição de superfície de polipeptídeos heterólogos em células bacterianas Gram-positivas. Ademais, a invenção repre senta bactérias quebradas por gene úteis para expressar as FBFP recombinantes sobre suas superfícies. Os construtos genéticos úteis para formar FBFP e métodos de utilização de FBFP também estão incluídos na invenção.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA200409786 | 2004-12-02 | ||
| PCT/IB2005/054022 WO2006072845A2 (en) | 2004-12-02 | 2005-12-02 | Gram positive bacterial cells comprising a disrupted flagellin gene, flagellin-based fusion proteins and use in removal of metal ions from a liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0515748A true BRPI0515748A (pt) | 2008-08-05 |
Family
ID=36586075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0515748-0A BRPI0515748A (pt) | 2004-12-02 | 2005-12-02 | proteìna recombinante produzida por bactérias gram-positivas, método para fabricá-la, para isolar ìons de metal de um lìquido, para converter um substrato em um produto, seu uso e respectivo kit |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7888064B2 (pt) |
| EP (1) | EP1836221B1 (pt) |
| JP (1) | JP2008521431A (pt) |
| CN (1) | CN101128480A (pt) |
| AT (1) | ATE518881T1 (pt) |
| AU (1) | AU2005323811B2 (pt) |
| BR (1) | BRPI0515748A (pt) |
| CA (1) | CA2588871A1 (pt) |
| NO (1) | NO20073288L (pt) |
| RU (1) | RU2007124731A (pt) |
| WO (1) | WO2006072845A2 (pt) |
| ZA (1) | ZA200704489B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794731B2 (en) * | 2004-12-16 | 2010-09-14 | Wake Forest University Health Sciences | Use of flagellin in the immunotherapy of Yersinia pestis |
| EP2235045B1 (en) * | 2008-01-08 | 2012-10-03 | Csir | Production of heterologous proteins or peptides |
| WO2010141312A2 (en) * | 2009-06-01 | 2010-12-09 | Wake Forest University Health Sciences | Flagellin fusion proteins and conjugates comprising pneumococcus antigens and methods of using the same |
| FR2949459B1 (fr) * | 2009-08-28 | 2014-10-17 | Otv Sa | Agent de prevention et/ou de lutte contre le moussage biologique |
| US8759044B2 (en) | 2011-03-23 | 2014-06-24 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| US8765425B2 (en) | 2011-03-23 | 2014-07-01 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| JP5943463B2 (ja) * | 2012-03-05 | 2016-07-05 | 国立大学法人神戸大学 | レアメタル結合能を有する人工ペプチドおよびその利用 |
| CN103031328B (zh) * | 2012-11-22 | 2015-08-05 | 江南大学 | 利用一种融合标签提高外源蛋白质的表达量 |
| JP2015100764A (ja) * | 2013-11-26 | 2015-06-04 | 株式会社東芝 | 汚泥処理装置、及び汚泥処理方法 |
| JP6377552B2 (ja) * | 2015-03-13 | 2018-08-22 | 株式会社東芝 | 汚泥処理システム |
| JP6377553B2 (ja) * | 2015-03-13 | 2018-08-22 | 株式会社東芝 | 汚泥処理システム |
| JP6591224B2 (ja) * | 2015-07-23 | 2019-10-16 | 株式会社東芝 | 処理装置及び処理方法 |
| US10849938B2 (en) | 2017-09-13 | 2020-12-01 | ZBiotics Company | Gene expression system for probiotic microorganisms |
| CN108060171B (zh) * | 2017-12-27 | 2020-11-06 | 中南大学 | 一种表面展示金属结合蛋白基因及其在回收铂钯金属中的应用 |
| SG11202105276TA (en) | 2018-12-03 | 2021-06-29 | Univ Texas | Oligo-benzamide analogs and their use in cancer treatment |
| CN111249444B (zh) * | 2020-03-10 | 2023-04-07 | 西北大学 | 一种用于抑制白色念珠菌的制剂 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987002385A1 (en) * | 1985-10-11 | 1987-04-23 | Genetics Institute, Inc. | Method for producing heterologous proteins |
| EP0237045B1 (en) * | 1986-03-11 | 1993-10-20 | Shionogi & Co., Ltd. | DNA encoding flagellin and vector having the same |
| JP2793673B2 (ja) | 1988-05-05 | 1998-09-03 | アメリカン・サイアナミド・カンパニー | 組み換えフラジエリンのワクチン |
| ES2176082B1 (es) * | 2000-05-31 | 2004-01-01 | Consejo Superior Investigacion | Bacterias con la capacidad de unir metales pesados y su empleo en la detoxificacion de medios contaminados con metales pesados. |
| WO2003011487A1 (en) | 2001-07-27 | 2003-02-13 | Global Biosciences, Inc. | Remediation of metal contaminants with hydrocarbon-utilizing bacteria |
| EP1488011A4 (en) * | 2002-03-13 | 2006-04-05 | New Century Pharmaceuticals | METHOD OF ISOLATING BINDING PEPTIDES FROM A COMBINATORIC PHAG DISPLAY LIBRARY AND PEPTIDES PRODUCED THEREFOR |
| DE10220094B4 (de) | 2002-05-04 | 2004-02-26 | Ontoprise Gmbh | Datenverarbeitungssystem |
| CA2485363C (en) * | 2002-05-10 | 2014-10-28 | New Century Pharmaceuticals, Inc. | Ferritin fusion proteins for use in vaccines and other applications |
| JP2006181393A (ja) * | 2003-03-10 | 2006-07-13 | Ip Bio Corp | ノンスラッジ高速排水処理システム |
| US7498403B2 (en) * | 2003-07-30 | 2009-03-03 | Japan Science And Technology Agency | Peptides capable of binding to titanium silver silicone |
-
2005
- 2005-12-02 EP EP05822486A patent/EP1836221B1/en not_active Expired - Lifetime
- 2005-12-02 JP JP2007543990A patent/JP2008521431A/ja not_active Abandoned
- 2005-12-02 US US11/792,242 patent/US7888064B2/en not_active Expired - Fee Related
- 2005-12-02 AU AU2005323811A patent/AU2005323811B2/en not_active Ceased
- 2005-12-02 BR BRPI0515748-0A patent/BRPI0515748A/pt not_active IP Right Cessation
- 2005-12-02 AT AT05822486T patent/ATE518881T1/de not_active IP Right Cessation
- 2005-12-02 CN CNA2005800466763A patent/CN101128480A/zh active Pending
- 2005-12-02 WO PCT/IB2005/054022 patent/WO2006072845A2/en not_active Ceased
- 2005-12-02 CA CA002588871A patent/CA2588871A1/en not_active Abandoned
- 2005-12-02 RU RU2007124731/13A patent/RU2007124731A/ru not_active Application Discontinuation
-
2007
- 2007-05-30 ZA ZA200704489A patent/ZA200704489B/xx unknown
- 2007-06-26 NO NO20073288A patent/NO20073288L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1836221A2 (en) | 2007-09-26 |
| ATE518881T1 (de) | 2011-08-15 |
| CA2588871A1 (en) | 2006-07-13 |
| RU2007124731A (ru) | 2009-01-10 |
| WO2006072845A3 (en) | 2007-03-01 |
| EP1836221B1 (en) | 2011-08-03 |
| ZA200704489B (en) | 2008-11-26 |
| AU2005323811A1 (en) | 2006-07-13 |
| WO2006072845A2 (en) | 2006-07-13 |
| AU2005323811B2 (en) | 2012-07-05 |
| NO20073288L (no) | 2007-08-16 |
| JP2008521431A (ja) | 2008-06-26 |
| US20080003237A1 (en) | 2008-01-03 |
| US7888064B2 (en) | 2011-02-15 |
| CN101128480A (zh) | 2008-02-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012. |