BRPI0516463A - cánula escalonada e conjunto de cánula - Google Patents

cánula escalonada e conjunto de cánula

Info

Publication number
BRPI0516463A
BRPI0516463A BRPI0516463-0A BRPI0516463A BRPI0516463A BR PI0516463 A BRPI0516463 A BR PI0516463A BR PI0516463 A BRPI0516463 A BR PI0516463A BR PI0516463 A BRPI0516463 A BR PI0516463A
Authority
BR
Brazil
Prior art keywords
cannula
stepped
cannulas
canned
delivering
Prior art date
Application number
BRPI0516463-0A
Other languages
English (en)
Inventor
Krzysztof Bankiewicz
Juger M Sommer
Original Assignee
Genzyme Corp
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp, Univ California filed Critical Genzyme Corp
Publication of BRPI0516463A publication Critical patent/BRPI0516463A/pt
Publication of BRPI0516463B1 publication Critical patent/BRPI0516463B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3478—Endoscopic needles, e.g. for infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B90/11—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0693—Brain, cerebrum

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

CáNULA ESCALONADA E CONJUNTO DE CáNULA. A presente invenção refere-se a cânulas tendo um exterior escalonado. Também são descritos métodos de fabricação e uso dessas cânulas, por exemplo, para entregar um ou mais materiais para o sistema nervoso central de um animal.
BRPI0516463-0A 2004-10-05 2005-10-05 sistema de entrega de um ou mais materiais BRPI0516463B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61623804P 2004-10-05 2004-10-05
US60/616,238 2004-10-05
US64155105P 2005-01-04 2005-01-04
US60/641,551 2005-01-04
PCT/US2005/036110 WO2006042090A1 (en) 2004-10-05 2005-10-05 Stepped cannula

Publications (2)

Publication Number Publication Date
BRPI0516463A true BRPI0516463A (pt) 2008-09-02
BRPI0516463B1 BRPI0516463B1 (pt) 2021-05-11

Family

ID=35762442

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516463-0A BRPI0516463B1 (pt) 2004-10-05 2005-10-05 sistema de entrega de um ou mais materiais

Country Status (15)

Country Link
US (4) US7815623B2 (pt)
EP (2) EP1807009B1 (pt)
JP (1) JP4838255B2 (pt)
CN (1) CN102626336A (pt)
AU (1) AU2005294247B2 (pt)
BR (1) BRPI0516463B1 (pt)
CA (1) CA2581714C (pt)
DK (1) DK1807009T3 (pt)
ES (1) ES2531425T3 (pt)
IL (2) IL182351A (pt)
MX (2) MX2007003850A (pt)
PL (2) PL1807009T3 (pt)
PT (1) PT1807009E (pt)
SI (1) SI1807009T1 (pt)
WO (1) WO2006042090A1 (pt)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI406688B (zh) * 2004-02-26 2013-09-01 Semiconductor Energy Lab 運動器具，娛樂工具，和訓練工具
CA2928387A1 (en) 2004-05-03 2005-11-17 Merrimack Pharmaceuticals, Inc. Drug delivery liposomes containing anionic polyols or anionic sugars
US8658203B2 (en) * 2004-05-03 2014-02-25 Merrimack Pharmaceuticals, Inc. Liposomes useful for drug delivery to the brain
PT1807009E (pt) * 2004-10-05 2015-02-25 Univ California Cânula escalonada
US20060253101A1 (en) * 2005-03-16 2006-11-09 Andreas Hartlep Intracranial catheter
AU2006283189B2 (en) * 2005-08-23 2013-01-31 The Regents Of The University Of California Reflux resistant cannula and system for chronic delivery of therapeutic agents using convection-enhanced delivery
US20070259031A1 (en) * 2006-04-26 2007-11-08 The Regents Of The University Of California Compositions and methods for convection enhanced delivery of high molecular weight neurotherapeutics
GB0616411D0 (en) * 2006-08-18 2006-09-27 Renishaw Plc Neurosurgical instruments
US7837668B2 (en) * 2006-10-10 2010-11-23 Ceregene, Inc. Needle assembly for use in delivering precise dosages of proteinaceous pharmaceutical compositions and methods for use of same
US7766394B2 (en) 2006-10-30 2010-08-03 Medtronic, Inc. Breakaway connectors and systems
EP1970001B1 (de) * 2007-03-16 2014-07-23 Brainlab AG Katheter mit Drucksensorik
US20080275466A1 (en) * 2007-05-01 2008-11-06 James Grant Skakoon Dual cannula system and method for using same
WO2008144585A1 (en) * 2007-05-17 2008-11-27 Medgenesis Therapeutix Inc. Convection-enhanced delivery catheter with removable stiffening member and method for using same
WO2009029508A1 (en) * 2007-08-28 2009-03-05 Johnnie B. Byrd, Sr. Alzheimer's Center And Research Institute, Inc. Intracranial catheter and methods of use
US8147480B2 (en) * 2007-09-28 2012-04-03 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US7766875B2 (en) * 2007-09-28 2010-08-03 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US8480626B2 (en) * 2007-11-30 2013-07-09 Medtronic, Inc. Infusion catheter assembly with reduced backflow
WO2009094389A1 (en) * 2008-01-22 2009-07-30 Medtronic, Inc. Burr hole anchors, systems, and methods
BRPI1007155A2 (pt) 2009-01-29 2017-05-30 Univ Of California San Francisco métodos para tratar um distúrbio neurológico cortical, e para dispensar um agente terapêutico para o córtex em um primata
PT2251454E (pt) 2009-05-13 2014-10-01 Sio2 Medical Products Inc Revestimento e inspeção de vaso
US7985188B2 (en) 2009-05-13 2011-07-26 Cv Holdings Llc Vessel, coating, inspection and processing apparatus
CN102625669B (zh) 2009-06-08 2015-09-23 核磁共振成像介入技术有限公司 能够近实时地跟踪和生成柔性体内装置的动态可视化的mri导向的介入系统
WO2010148083A2 (en) 2009-06-16 2010-12-23 Surgivision, Inc. Mri-guided devices and mri-guided interventional systems that can track and generate dynamic visualizations of the devices in near real time
US9458536B2 (en) 2009-07-02 2016-10-04 Sio2 Medical Products, Inc. PECVD coating methods for capped syringes, cartridges and other articles
WO2011025775A1 (en) * 2009-08-24 2011-03-03 Alterman Ron L Apparatus for trans-cerebral electrophoresis and methods of use thereof
PL2558154T3 (pl) 2010-04-16 2020-11-30 Clearpoint Neuro, Inc. Systemy chirurgiczne MRI zawierające kaniule chirurgiczne kompatybilne z MRI do transferu substancji do i/lub od pacjenta
US8738151B2 (en) 2010-04-28 2014-05-27 Medtronic, Inc. Body portal anchors and systems
US11624115B2 (en) 2010-05-12 2023-04-11 Sio2 Medical Products, Inc. Syringe with PECVD lubrication
US9878101B2 (en) 2010-11-12 2018-01-30 Sio2 Medical Products, Inc. Cyclic olefin polymer vessels and vessel coating methods
US9272095B2 (en) 2011-04-01 2016-03-01 Sio2 Medical Products, Inc. Vessels, contact surfaces, and coating and inspection apparatus and methods
US20130035660A1 (en) 2011-08-01 2013-02-07 Alcyone Lifesciences, Inc. Multidirectional microfluidic drug delivery devices with conformable balloons
US11116695B2 (en) 2011-11-11 2021-09-14 Sio2 Medical Products, Inc. Blood sample collection tube
CA2855353C (en) 2011-11-11 2021-01-19 Sio2 Medical Products, Inc. Passivation, ph protective or lubricity coating for pharmaceutical package, coating process and apparatus
WO2013144901A2 (en) * 2012-03-30 2013-10-03 Koninklijke Philips N.V. Nested cannula tips
EP2846755A1 (en) 2012-05-09 2015-03-18 SiO2 Medical Products, Inc. Saccharide protective coating for pharmaceutical package
US20150297800A1 (en) 2012-07-03 2015-10-22 Sio2 Medical Products, Inc. SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS
CN104582610B (zh) 2012-07-24 2018-03-20 瑞尼斯豪公司 神经外科设备和方法
US8992427B2 (en) 2012-09-07 2015-03-31 Gynesonics, Inc. Methods and systems for controlled deployment of needle structures in tissue
US20140243783A1 (en) * 2012-10-06 2014-08-28 Raghu Raghavan Method of backflow reduction during material delivery through a needle into tissue
US9664626B2 (en) 2012-11-01 2017-05-30 Sio2 Medical Products, Inc. Coating inspection method
WO2014078666A1 (en) 2012-11-16 2014-05-22 Sio2 Medical Products, Inc. Method and apparatus for detecting rapid barrier coating integrity characteristics
US9764093B2 (en) 2012-11-30 2017-09-19 Sio2 Medical Products, Inc. Controlling the uniformity of PECVD deposition
AU2013352436B2 (en) 2012-11-30 2018-10-25 Sio2 Medical Products, Inc. Controlling the uniformity of PECVD deposition on medical syringes, cartridges, and the like
CA2895509C (en) 2012-12-18 2021-08-17 Alcyone Lifesciences, Inc. Systems and methods for reducing or preventing backflow in a delivery system
US9662450B2 (en) 2013-03-01 2017-05-30 Sio2 Medical Products, Inc. Plasma or CVD pre-treatment for lubricated pharmaceutical package, coating process and apparatus
CN105392916B (zh) 2013-03-11 2019-03-08 Sio2医药产品公司 涂布包装材料
US9937099B2 (en) 2013-03-11 2018-04-10 Sio2 Medical Products, Inc. Trilayer coated pharmaceutical packaging with low oxygen transmission rate
EP2971227B1 (en) 2013-03-15 2017-11-15 Si02 Medical Products, Inc. Coating method.
CA2910268C (en) 2013-04-30 2021-01-12 Cedars-Sinai Medical Center Stabilization apparatuses and methods for medical procedures
US10456533B2 (en) 2013-06-17 2019-10-29 Alcyone Lifesciences, Inc. Methods and devices for protecting catheter tips and stereotactic fixtures for microcatheters
EP3027259B1 (en) 2013-07-31 2019-03-13 Alcyone Lifesciences, Inc. Systems and methods for drug delivery, treatment, and monitoring
US9891296B2 (en) 2013-09-13 2018-02-13 MRI Interventions, Inc. Intrabody fluid transfer devices, systems and methods
US9849266B2 (en) * 2014-02-20 2017-12-26 Brainlab Ag Agent delivery catheter
WO2015148471A1 (en) 2014-03-28 2015-10-01 Sio2 Medical Products, Inc. Antistatic coatings for plastic vessels
IL248102B (en) 2014-05-02 2022-07-01 Genzyme Corp aav vectors for gene therapy of the central nervous system and retina
WO2015191508A1 (en) 2014-06-09 2015-12-17 Voyager Therapeutics, Inc. Chimeric capsids
CN107106814B (zh) 2014-10-29 2021-02-26 西达-赛奈医疗中心 一种用于治疗剂和相关物质的受控输送的设备、系统和方法
SG11201703148TA (en) 2014-11-05 2017-05-30 Voyager Therapeutics Inc Aadc polynucleotides for the treatment of parkinson's disease
WO2016077607A1 (en) * 2014-11-13 2016-05-19 The Regents Of The University Of California Adjustable stepped cannula
CN119876138A (zh) 2014-11-14 2025-04-25 沃雅戈治疗公司 调节性多核苷酸
CA3193811A1 (en) 2014-11-14 2016-05-19 Voyager Therapeutics, Inc. Compositions and methods of treating amyotrophic lateral sclerosis (als)
HK1245326A1 (zh) 2014-12-12 2018-08-24 Voyager Therapeutics, Inc. 用於生产scaav的组合物和方法
US10806396B2 (en) 2015-01-26 2020-10-20 Alcyone Lifesciences, Inc. Drug delivery methods with tracer
TN2017000353A1 (en) 2015-02-10 2019-01-16 Genzyme Corp Enhanced delivery of viral particles to the striatum and cortex
CA2985347A1 (en) 2015-05-11 2016-11-17 Alcyone Lifesciences, Inc. Drug delivery systems and methods
KR102786617B1 (ko) 2015-08-18 2025-03-26 에스아이오2 메디컬 프로덕츠, 엘엘씨 산소 전달률이 낮은, 의약품 및 다른 제품의 포장용기
WO2017053753A1 (en) 2015-09-23 2017-03-30 Sangamo Biosciences, Inc. Htt repressors and uses thereof
MX382522B (es) 2015-10-16 2025-03-13 Ipsen Biopharm Ltd Composiciones farmaceuticas estabilizantes de camptotecina.
KR20180100606A (ko) 2016-01-04 2018-09-11 알시온 라이프사이언스 인크. 뇌졸중을 치료하기 위한 방법들 및 장치들
EP3393571B1 (en) * 2016-02-17 2024-03-06 ClearPoint Neuro, Inc. Intrabody surgical fluid transfer assemblies with adjustable exposed cannula to needle tip length, related systems and methods
EP3448987A4 (en) 2016-04-29 2020-05-27 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
EP3448874A4 (en) 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
CA3024449A1 (en) 2016-05-18 2017-11-23 Voyager Therapeutics, Inc. Compositions and methods of treating huntington's disease
CA3024448C (en) 2016-05-18 2025-09-09 Voyager Therapeutics, Inc. MODULATING POLYNUCLEOTIDES
WO2018044933A1 (en) 2016-08-30 2018-03-08 The Regents Of The University Of California Methods for biomedical targeting and delivery and devices and systems for practicing the same
EP3537982B1 (en) 2016-11-11 2022-09-07 Gynesonics, Inc. Controlled treatment of tissue and dynamic interaction with tissue and/or treatment data and comparison of tissue and/or treatment data
CN110214184B (zh) 2016-12-01 2024-07-02 桑格摩生物治疗股份有限公司 τ蛋白调节剂以及用于其递送的方法和组合物
US10653442B2 (en) * 2016-12-21 2020-05-19 Alcyone Lifesciences, Inc. Drug delivery systems and methods
JP2020518259A (ja) 2017-05-05 2020-06-25 ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ハンチントン病治療組成物および方法
EP3618839A4 (en) 2017-05-05 2021-06-09 Voyager Therapeutics, Inc. COMPOSITIONS AND METHODS OF TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
JOP20190269A1 (ar) 2017-06-15 2019-11-20 Voyager Therapeutics Inc بولي نوكليوتيدات aadc لعلاج مرض باركنسون
JP7229989B2 (ja) 2017-07-17 2023-02-28 ボイジャー セラピューティクス インコーポレイテッド 軌道アレイガイドシステム
US20200263199A1 (en) 2017-09-29 2020-08-20 Voyager Therapeutics, Inc. Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery
TW202413649A (zh) 2017-10-16 2024-04-01 美商航海家醫療公司 肌萎縮性脊髓側索硬化症(als)之治療
WO2019079242A1 (en) 2017-10-16 2019-04-25 Voyager Therapeutics, Inc. TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
WO2019216953A1 (en) * 2018-05-09 2019-11-14 MRI Interventions, Inc. Mri compatible intrabody fluid transfer systems and related devices and methods
US11253237B2 (en) 2018-05-09 2022-02-22 Clearpoint Neuro, Inc. MRI compatible intrabody fluid transfer systems and related devices and methods
SG11202011296VA (en) 2018-05-15 2020-12-30 Voyager Therapeutics Inc Compositions and methods for the treatment of parkinson's disease
WO2020010035A1 (en) * 2018-07-02 2020-01-09 Voyager Therapeutics, Inc. Cannula system
US12281321B2 (en) 2018-09-28 2025-04-22 Voyager Therapeutics, Inc. Frataxin expression constructs having engineered promoters and methods of use thereof
KR20210070344A (ko) 2018-10-02 2021-06-14 상가모 테라퓨틱스, 인코포레이티드 타우 단백질의 조정을 위한 방법 및 조성물
JP7633934B2 (ja) * 2019-02-08 2025-02-20 リバウンド セラピュティクス コーポレーション 照明付きカニューレ・システム
MX2021012836A (es) 2019-04-23 2021-12-10 Sangamo Therapeutics Inc Moduladores de la expresion del gen del marco de lectura abierto 72 del cromosoma 9 y usos de los mismos.
US12544538B2 (en) * 2019-05-31 2026-02-10 The Trustees Of The University Of Pennsylvania Infusion device and method for drug delivery
US11684750B2 (en) 2019-10-08 2023-06-27 Clearpoint Neuro, Inc. Extension tube assembly and related medical fluid transfer systems and methods
US20210318397A1 (en) * 2020-04-08 2021-10-14 Clearpoint Neuro, Inc. Mri surgical systems including mri-compatible surgical cannulas for transferring a substance to and/or from a patient
GB2601752A (en) 2020-12-08 2022-06-15 Maavrx Ltd Expression vector
WO2025004001A1 (en) 2023-06-30 2025-01-02 Takeda Pharmaceutical Company Limited Htt repressors and uses thereof

Family Cites Families (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1255551A (en) 1968-03-30 1971-12-01 Heraeus Schott Quarzschmelze Improvements in or relating to externally coated fused silica tube
LU77252A1 (pt) * 1976-05-06 1977-08-22
US4239042A (en) * 1979-04-05 1980-12-16 Dow Corning K.K. Catheter placement system
DE3025785C2 (de) * 1980-07-08 1984-08-16 Storz, Karl, 7200 Tuttlingen Dilatator, Verfahren zu seiner Verwendung und Vorrichtung zur Durchführung des Verfahrens
US4335718A (en) * 1980-10-02 1982-06-22 Becton, Dickinson And Company Needle cannula
US4448532A (en) * 1981-03-31 1984-05-15 Kla Instruments Corporation Automatic photomask inspection method and system
DE8222222U1 (de) * 1982-08-06 1982-11-25 Mehler, Doron, Dr., 3000 Hannover Katheterset
JPS60234671A (ja) * 1984-05-09 1985-11-21 テルモ株式会社 カテ−テル導入具
US4597421A (en) * 1984-11-19 1986-07-01 Varian Associates, Inc. Method and device for on-column injection of a liquid sample into small diameter columns
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US4739768B2 (en) * 1986-06-02 1995-10-24 Target Therapeutics Inc Catheter for guide-wire tracking
US4738658A (en) * 1986-09-19 1988-04-19 Aries Medical Incorporated Tapered hemostatic device for use in conjunction with a catheter for alleviating blood leakage and method for using same
US5219740A (en) 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
US4781691A (en) * 1987-07-17 1988-11-01 The Kendall Company Stepped needle
US4909800A (en) * 1987-07-17 1990-03-20 The Kendall Company Stepped needle
DE8714069U1 (de) * 1987-10-21 1987-12-03 Richard Wolf Gmbh, 7134 Knittlingen Endoskopischer Instrumentensatz
US4978334A (en) * 1988-09-08 1990-12-18 Toye Frederic J Apparatus and method for providing passage into body viscus
US5069673A (en) * 1990-02-07 1991-12-03 Cordis Corporation Catheter with double step-down bore
WO1992001070A1 (en) 1990-07-09 1992-01-23 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce High efficiency packaging of mutant adeno-associated virus using amber suppressions
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5256157A (en) * 1991-01-31 1993-10-26 Baxter International Inc. Automated infusion pump with replaceable memory cartridges
JP3534749B2 (ja) 1991-08-20 2004-06-07 アメリカ合衆国 アデノウイルスが介在する胃腸管への遺伝子の輸送
AU7676894A (en) * 1993-08-27 1995-03-21 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Convection-enhanced drug delivery
NL9301642A (nl) * 1993-09-22 1995-04-18 Cordis Europ Microcatheter.
US5626862A (en) * 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
JP3573531B2 (ja) * 1994-08-03 2004-10-06 鐘淵化学工業株式会社 マイクロカテーテル
SI0833934T2 (sl) 1995-06-15 2013-04-30 Crucell Holland B.V. Pakirni sistemi za humani rekombinantni adenovirus za uporabo v genski terapiji
US6001650A (en) 1995-08-03 1999-12-14 Avigen, Inc. High-efficiency wild-type-free AAV helper functions
US5622856A (en) 1995-08-03 1997-04-22 Avigen High efficiency helper system for AAV vector production
US5593393A (en) * 1995-09-07 1997-01-14 Trudell; Roger J. Lacrimal irrigating cannula
US6351659B1 (en) * 1995-09-28 2002-02-26 Brainlab Med. Computersysteme Gmbh Neuro-navigation system
US6004797A (en) 1995-11-09 1999-12-21 Avigen, Inc. Adenovirus helper-free recombinant AAV Virion production
US6020196A (en) * 1996-05-09 2000-02-01 Baxter International Inc. Devices for harvesting and homogenizing adipose tissue containing autologous endothelial cells
US5902282A (en) * 1996-12-26 1999-05-11 Johnson & Johnson Medical, Inc. Step-down catheter
US6048551A (en) 1997-03-27 2000-04-11 Hilfinger; John M. Microsphere encapsulation of gene transfer vectors
US6458088B1 (en) * 1997-03-27 2002-10-01 Cordis Corporation Glass core guidewire compatible with magnetic resonance
US6524299B1 (en) * 1997-04-09 2003-02-25 Target Therapeutics, Inc. Flow-directed catheter
US6042579A (en) * 1997-04-30 2000-03-28 Medtronic, Inc. Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain
US6026316A (en) * 1997-05-15 2000-02-15 Regents Of The University Of Minnesota Method and apparatus for use with MR imaging
US6030369A (en) * 1997-07-03 2000-02-29 Target Therapeutics Inc. Micro catheter shaft
US6186986B1 (en) * 1998-01-21 2001-02-13 St. Jude Medical Cardiovascular Group, Inc. Micro-catheters and methods of their manufacture
US6199554B1 (en) * 1998-03-27 2001-03-13 The Brigham And Women's Hospital, Inc. Method and apparatus for combining injury-mediated therapy and drug delivery
DE69929600T2 (de) * 1998-05-27 2006-09-07 Avigen Inc., Alameda Konvektion-erhöhte verabreichung aadc-kodierende aav vektoren
US6210392B1 (en) * 1999-01-15 2001-04-03 Interventional Technologies, Inc. Method for treating a wall of a blood vessel
US6663606B1 (en) * 1999-10-28 2003-12-16 Scimed Life Systems, Inc. Biocompatible medical devices
US6579484B1 (en) * 1999-12-16 2003-06-17 Advanced Cardiovascular Systems, Inc. Co-extruded taper shaft
US20040092879A1 (en) * 2000-11-06 2004-05-13 Medamicus, Inc. Safety introducer apparatus and method therefor
US6641564B1 (en) * 2000-11-06 2003-11-04 Medamicus, Inc. Safety introducer apparatus and method therefor
CA2327208A1 (en) * 2000-11-30 2002-05-30 The Government Of The United States Of America Methods of increasing distribution of therapeutic agents
US20020087152A1 (en) * 2001-01-04 2002-07-04 Endocare, Inc. Systems and methods for delivering a probe into tissue
US6533751B2 (en) * 2001-01-09 2003-03-18 Andrew Cragg Micro catheter and guidewire system having improved pushability and control
JP4271444B2 (ja) * 2001-01-31 2009-06-03 富士通株式会社 歪補償装置
US7182944B2 (en) * 2001-04-25 2007-02-27 The United States Of America As Represented By The Department Of Health And Human Services Methods of increasing distribution of nucleic acids
US20030073934A1 (en) * 2001-10-17 2003-04-17 David A. Putz Double slotted-cannula device and method of use
EP1491154A1 (en) 2002-01-22 2004-12-29 JFE Steel Corporation Ceramic-coated instruments for medical use, ceramic-coated instruments for studying living organisms and process for producing the same
JP2004147830A (ja) * 2002-10-30 2004-05-27 Jfe Steel Kk 遺伝子制御用セラミック被覆針およびその製造方法およびその製造装置
GB0205772D0 (en) * 2002-03-12 2002-04-24 Gill Steven S Catheter
US20050256503A1 (en) * 2002-05-07 2005-11-17 Cardiac Pacemakers, Inc. Tapered catheter delivery system
EP3067070A1 (en) * 2002-09-24 2016-09-14 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Method for convection enhanced delivery of therapeutic agents
ES2342376T3 (es) 2002-10-10 2010-07-06 Becton Dickinson And Company Conjunto de aguja para la administracion de anestesia local.
US20040209810A1 (en) * 2003-02-24 2004-10-21 Gill Steven S. Method of treating Parkinson's disease in humans by intraputaminal infusion of glial cell-line derived neurotrophic factor
US7241283B2 (en) * 2003-04-25 2007-07-10 Ad-Tech Medical Instrument Corp. Method for intracranial catheter treatment of brain tissue
US8658203B2 (en) * 2004-05-03 2014-02-25 Merrimack Pharmaceuticals, Inc. Liposomes useful for drug delivery to the brain
JP4449587B2 (ja) * 2004-06-09 2010-04-14 富士フイルム株式会社 画像マッピング方法及び画像マッピングプログラム
US20060073119A1 (en) * 2004-09-01 2006-04-06 Avigen, Inc. Methods for treating neurodegenerative disorders
PT1807009E (pt) * 2004-10-05 2015-02-25 Univ California Cânula escalonada
US20060217664A1 (en) * 2004-11-15 2006-09-28 Hattler Brack G Telescoping vascular dilator
US20060129126A1 (en) * 2004-11-19 2006-06-15 Kaplitt Michael G Infusion device and method for infusing material into the brain of a patient
AU2006283189B2 (en) * 2005-08-23 2013-01-31 The Regents Of The University Of California Reflux resistant cannula and system for chronic delivery of therapeutic agents using convection-enhanced delivery
WO2007127803A2 (en) * 2006-04-25 2007-11-08 The Regents Of The University Of California Administration of growth factors for the treatment of cns disorders
GB0616411D0 (en) * 2006-08-18 2006-09-27 Renishaw Plc Neurosurgical instruments
EP1974755A1 (de) * 2007-03-16 2008-10-01 BrainLAB AG Katheter mit sich ändernden Materialeigenschaften
US8147480B2 (en) * 2007-09-28 2012-04-03 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US7766875B2 (en) * 2007-09-28 2010-08-03 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US8480626B2 (en) * 2007-11-30 2013-07-09 Medtronic, Inc. Infusion catheter assembly with reduced backflow

Also Published As

Publication number Publication date
JP2008515554A (ja) 2008-05-15
US20130079748A1 (en) 2013-03-28
US8337458B2 (en) 2012-12-25
CN102626336A (zh) 2012-08-08
EP2572661B1 (en) 2019-11-20
PT1807009E (pt) 2015-02-25
MX2007003850A (es) 2007-11-21
MX349748B (es) 2017-08-09
US9302070B2 (en) 2016-04-05
EP2572661A1 (en) 2013-03-27
IL182351A0 (en) 2007-07-24
IL182351A (en) 2012-04-30
WO2006042090A1 (en) 2006-04-20
PL1807009T3 (pl) 2015-06-30
ES2531425T3 (es) 2015-03-13
DK1807009T3 (en) 2015-03-02
EP1807009B1 (en) 2014-11-26
AU2005294247B2 (en) 2011-08-11
CA2581714A1 (en) 2006-04-20
SI1807009T1 (sl) 2015-04-30
AU2005294247A1 (en) 2006-04-20
US20110046552A1 (en) 2011-02-24
CA2581714C (en) 2017-09-12
PL2572661T3 (pl) 2020-06-01
US20160296694A1 (en) 2016-10-13
IL218812A0 (en) 2012-05-31
BRPI0516463B1 (pt) 2021-05-11
US20060135945A1 (en) 2006-06-22
JP4838255B2 (ja) 2011-12-14
US7815623B2 (en) 2010-10-19
EP1807009A1 (en) 2007-07-18

Similar Documents

Publication Publication Date Title
BRPI0516463A (pt) cánula escalonada e conjunto de cánula
BRPI0007487B8 (pt) difenil-uréias substituídas com w-carbóxi-arilas como inibidores de raf cinase
CY1119742T1 (el) Βιολογικα συστηματα μεταφορας πολλαπλου-συστατικου
NO20093060L (no) Spirosykliske sykloheksanderivater
BR0310077A (pt) Novos compostos e sua utilização
BR0309875A (pt) métodos e composições para tratamento de distúrbios do sistema nervoso periférico e novos compostos úteis para isto
BR0208338A (pt) Derivados de piridina
BRPI0418099A (pt) compostos, composição farmacêutica, e uso de um composto
WO2003104425A3 (en) NEW STABLE ANTI-CD22 ANTIBODIES
DK1472344T3 (da) Bakteriofaglysin
BR0317284A (pt) Inibidores aminocianopiridina de proteìna quinase-2 ativada com proteìna quinase ativada com mitógeno
PY990129A (es) Bromhidrato de eletriptan monohidratado
BR0112131A (pt) Composições farmacêuticas e métodos para uso
ES2057341T3 (es) Ciclohexenos substituidos como agentes para el sistema nervioso central.
CY1110105T1 (el) Σκευασματα σκιαγραφικων μεσων που εχουν βελτιωμενη ανεκτικοτητα
ATE434044T1 (de) Antikörper gegen tumorspezifisches antigen als ziel
WO2004056861A3 (en) Glycoisoforms of adiponectin and uses thereof
MY140530A (en) Antineoplasic compounds and pharmaceuticals compositions thereof
GT200100184A (es) Amidas de acido fenilciclohexanocarboxilico sustituido y su uso.
BRPI0414527A (pt) tratamento de tumores estromáticos gastrointestinais com imatinib e midostaurina
WO2004017909A3 (en) Methods of reducing ischemic injury
CY1117415T1 (el) Διαβαθμισμενη κανουλα
IT1316596B1 (it) Sistema di distribuzione di documenti,come i referti di un laboratorio di analisi mediche od altro.
TH81375A (th) สารประกอบใหม่
GT199700113A (es) Tetrahidro - 6h - pirazino ( 1, 2 - b ) isoquinolin - 1, 4 - dionas.

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/10/2005, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME MEDIDA CAUTELAR DE 07/04/2021 - ADI 5.529/DF