BRPI0517719A - composição veterinária transmucosal compreendendo detomidina - Google Patents

composição veterinária transmucosal compreendendo detomidina

Info

Publication number
BRPI0517719A
BRPI0517719A BRPI0517719-7A BRPI0517719A BRPI0517719A BR PI0517719 A BRPI0517719 A BR PI0517719A BR PI0517719 A BRPI0517719 A BR PI0517719A BR PI0517719 A BRPI0517719 A BR PI0517719A
Authority
BR
Brazil
Prior art keywords
transmucosal
detomidine
veterinary composition
composition
semi
Prior art date
Application number
BRPI0517719-7A
Other languages
English (en)
Inventor
Mirja Huhtinen
Piritta Koistinen
Lasse Leino
Maria Rantala
Helena Kaukinen
Ursin Kaija Af
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Publication of BRPI0517719A publication Critical patent/BRPI0517719A/pt
Publication of BRPI0517719B1 publication Critical patent/BRPI0517719B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)

Abstract

COMPOSIçãO VETERINáRIA TRANSMUCOSAL COMPREENDENDO DETOMIDINA.A presente invenção se refere a uma composição veterinária em uma formasemi-sólida adaptada para administração transmucosal para fornecer sedação e analgesia em animais de grande porte tais como cavalos e gado A composição transmucosal semi-sólida da invenção compreende detomidinaou um sal farmaceuticamente aceitável desta como um ingrediente ativo. A composição fornece um início rápido de ação enquanto tendo potencial de irritação baixo na mucosa oral.
BRPI0517719A 2004-11-05 2005-11-03 composição veterinária farmacêutica na forma de um gel transmucosal e kit veterinário BRPI0517719B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62512904P 2004-11-05 2004-11-05
FI20041425A FI20041425A0 (fi) 2004-11-05 2004-11-05 Transmukosaalinen veterinäärinen koostumus
PCT/FI2005/000470 WO2006048501A1 (en) 2004-11-05 2005-11-03 A transmucosal veterinary composition comprising detomidine

Publications (2)

Publication Number Publication Date
BRPI0517719A true BRPI0517719A (pt) 2008-10-21
BRPI0517719B1 BRPI0517719B1 (pt) 2018-11-06

Family

ID=33515193

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0517719A BRPI0517719B1 (pt) 2004-11-05 2005-11-03 composição veterinária farmacêutica na forma de um gel transmucosal e kit veterinário

Country Status (22)

Country Link
US (2) US7863311B2 (pt)
EP (1) EP1811995B1 (pt)
JP (1) JP4996472B2 (pt)
KR (1) KR101257672B1 (pt)
AR (1) AR054987A1 (pt)
AU (1) AU2005300451B2 (pt)
BR (1) BRPI0517719B1 (pt)
CA (1) CA2583876C (pt)
DK (1) DK1811995T3 (pt)
ES (1) ES2388442T3 (pt)
FI (1) FI20041425A0 (pt)
HR (1) HRP20120856T1 (pt)
IL (1) IL182541A (pt)
MX (1) MX2007005238A (pt)
NO (1) NO338158B1 (pt)
NZ (1) NZ554521A (pt)
PL (1) PL1811995T3 (pt)
PT (1) PT1811995E (pt)
RS (1) RS52504B (pt)
SI (1) SI1811995T1 (pt)
WO (1) WO2006048501A1 (pt)
ZA (1) ZA200703486B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
ES2393814T3 (es) * 2007-04-04 2012-12-28 Sigmoid Pharma Limited Una composición farmacéutica oral
US20090246256A1 (en) * 2008-03-27 2009-10-01 Al-Ghananeem Abeer M Compositions and Methods for Transmucosal Delivery of Lofexidine
KR101517415B1 (ko) * 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물
BR112012004841A2 (pt) * 2009-09-04 2018-03-13 Shiseido Company, Ltd. método de produção de emulsão de óleo/água
US8722636B2 (en) 2011-01-31 2014-05-13 New Market Pharmaceuticals, LLC Animal treatments
US10064849B2 (en) 2012-05-02 2018-09-04 New Market Pharmaceuticals Pharmaceutical compositions for direct systemic introduction
ES3034104T3 (en) 2012-05-02 2025-08-13 Newmarket Pharmaceuticals Llc Pharmaceutical compositions for direct systemic introduction
FR2990134B1 (fr) * 2012-05-07 2014-11-21 Anaconda Pharma Composition pharmaceutique d'un inhibiteur du virus du papillome
CA2884926C (en) * 2012-10-15 2021-09-21 Orion Corporation A veterinary method of alleviating noise aversion
AU2013361057A1 (en) * 2012-12-21 2015-07-30 Teva Pharmaceutical Industries Ltd. Oral transmucosal delivery of glatiramer acetate
FI127534B (en) * 2014-11-10 2018-08-31 Vetcare Oy Substituted benzoefuroquinolizine and ɑ2-adrenergic agonist comprising compositions
WO2018129313A1 (en) * 2017-01-06 2018-07-12 Clexio Biosciences Ltd. Topical detomidine formulations
JP2021529811A (ja) * 2018-07-11 2021-11-04 クレキシオ バイオサイエンシーズ エルティーディー． 局所用デトミジン製剤
EP3962478A1 (en) 2019-05-01 2022-03-09 Clexio Biosciences Ltd. Methods of treating pruritus
WO2020243538A1 (en) * 2019-05-31 2020-12-03 Primo Pharmatech Llc Unit dosage form for transmucosal drug delivery of an active pharmaceutical ingredient

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
FI844786A0 (fi) * 1984-12-04 1984-12-04 Farmos Oy Terapeutiskt utnyttjbar foerening.
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
GB2256135B (en) 1991-05-31 1995-01-18 Orion Yhtymae Oy Transdermal administration of 4-substituted imidazoles
MX9304075A (es) * 1992-07-08 1994-04-29 Applied Research Systems Composicion farmaceutica para el tratamiento o profilaxis de los desordenes trombohemorragicos consuntivos.
CN1106259A (zh) 1994-02-05 1995-08-09 日东制药株式会社 含有作为有效成分的丙酸类非类固醇性药物的新颖消炎镇痛外用凝胶制剂
EP1021204B1 (en) * 1997-09-26 2005-12-28 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
MXPA01003310A (es) * 1998-10-02 2003-05-15 3M Innovative Properties Co Sistema de suministro de farmaco originados en mucosa y aplicaciones animales.
US7001609B1 (en) * 1998-10-02 2006-02-21 Regents Of The University Of Minnesota Mucosal originated drug delivery systems and animal applications
ATE485837T1 (de) 2000-08-03 2010-11-15 Antares Pharma Ipl Ag Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert
JP4493203B2 (ja) 2000-12-12 2010-06-30 株式会社ブリヂストン 空気入りタイヤの製造方法
DE10107659B4 (de) * 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin
DE10256774A1 (de) * 2002-12-05 2004-06-24 Lts Lohmann Therapie-Systeme Ag Transmucosale und transdermale Arzneimittel mit verbesserter Wirkstoffresorption

Also Published As

Publication number Publication date
JP4996472B2 (ja) 2012-08-08
IL182541A (en) 2011-02-28
DK1811995T3 (da) 2012-08-20
MX2007005238A (es) 2007-07-09
US20110071203A1 (en) 2011-03-24
AR054987A1 (es) 2007-08-01
IL182541A0 (en) 2007-09-20
EP1811995A1 (en) 2007-08-01
NZ554521A (en) 2010-09-30
KR20070085284A (ko) 2007-08-27
HRP20120856T1 (hr) 2012-11-30
BRPI0517719B1 (pt) 2018-11-06
AU2005300451A1 (en) 2006-05-11
PT1811995E (pt) 2012-08-03
AU2005300451B2 (en) 2011-01-20
PL1811995T3 (pl) 2012-12-31
ES2388442T3 (es) 2012-10-15
EP1811995B1 (en) 2012-07-25
NO20072864L (no) 2007-06-05
US20070299121A1 (en) 2007-12-27
US7863311B2 (en) 2011-01-04
RS52504B (sr) 2013-04-30
US8309591B2 (en) 2012-11-13
CA2583876C (en) 2012-05-29
SI1811995T1 (sl) 2012-10-30
CA2583876A1 (en) 2006-05-11
KR101257672B1 (ko) 2013-04-24
JP2008519012A (ja) 2008-06-05
FI20041425A0 (fi) 2004-11-05
WO2006048501A1 (en) 2006-05-11
NO338158B1 (no) 2016-08-01
ZA200703486B (en) 2008-06-25

Similar Documents

Publication Publication Date Title
BRPI0517719A (pt) composição veterinária transmucosal compreendendo detomidina
BRPI0516830A (pt) composições de droga de liberação sustentada convenientemente implantáveis
AR045972A1 (es) Formulaciones de tramadol de liberacion sostenida con eficacia de 24 horas
AR045142A1 (es) Composicion veterinaria masticable ductil de buen sabor
ES2295609T3 (es) Derivados de tiadiazolilpiperazina utiles para tratar o prevenir un dolor.
ES2565190T3 (es) Reducción de mareos, un efecto secundario asociado a la terapia de pirfenidona
CY1118179T1 (el) Φαρμακευτικη συνθεση
BR0201719A (pt) Composições farmacêuticas agradáveis ao paladar para animais de companhia
AR058679A1 (es) Preparacion farmaceutica que contiene meloxicam
BRPI0512311A (pt) uso de meloxicam em medicina veterinária para o tratamento de doenças inflamatórias dolorosas
BRPI0512274A (pt) derivados de piperazina aril-substituìdos
SE0002754D0 (sv) New pharmaceutical combination formulation and method of treatment with the combination
BR0013116A (pt) Tratamento oral de animais de estimação com espinosinas ectoparasiticidas
AR098251A2 (es) Uso de aivlosin o de una sal de adición ácida del mismo farmacológicamente aceptada para la preparación de un medicamento de uso veterinario, un alimento para aves de corral o cerdos, una composición recubierta estable para ser agregada a dicho alimento y un medicamento de uso veterinario
BRPI0912112B8 (pt) composição farmacêutica compreendendo composto tendo atividade antagonística em receptor de adenosina a2a útil em suprimir tolerância analgésica
BR0214497A (pt) Composição farmacêutica que compreende um agonista do receptor 5ht1
BRPI0510449A (pt) uso de formulações de meloxicam em medicina veterinária
Jenkins Diseases of geriatric guinea pigs and chinchillas
Júnior et al. Oral myiasis caused by Cochliomyia hominivorax treated nonsurgically with nitrofurazone: report of 2 cases
AR048806A1 (es) Uso de cariofilenos en la elaboracion de medicamentos y tratamiento de afecciones corporales de inflamacion y dolor inflamatorio
AR019579A1 (es) USO DE UN INICIADOR DE LA RESPUESTA SEXUAL DEL SISTEMA NERVIOSO CENTRAL PARA LA FABRICACIoN DE UNA COMPOSICIoN FARMACÉUTICA PARA LA NORMALIZACIoN DE LA CRONOMETRACIoN DE LA RESPUESTA SEXUAL O PARA LA PROFILAXIS O REDUCCIoN DE LA LESIoN TISULAR GENITAL EN MAMíFEROS
BRPI0418764A (pt) uso de espinosina ou um derivado ou sal da mesma fisiologicamente aceitável
Delacalle et al. Nd: YAG Laser–Assisted Modified Forssell's Procedure for Treatment of Cribbing (Crib‐Biting) in Horses
Udegbunam et al. Evaluation of local anaesthetic efficacy of the crude extract of Sterculia tragacantha using West African Dwarf Goats
Fragkou et al. Observations in ovine myiosis in Greece, with special reference to clinical findings and treatment of genital myiosis

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.

B08G Application fees: restoration [chapter 8.7 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07C Technical examination (opinion): republication [chapter 7.3 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 06/11/2018, OBSERVADAS AS CONDICOES LEGAIS.