BRPI0517719A - composição veterinária transmucosal compreendendo detomidina - Google Patents

composição veterinária transmucosal compreendendo detomidina

Info

Publication number
BRPI0517719A
BRPI0517719A BRPI0517719-7A BRPI0517719A BRPI0517719A BR PI0517719 A BRPI0517719 A BR PI0517719A BR PI0517719 A BRPI0517719 A BR PI0517719A BR PI0517719 A BRPI0517719 A BR PI0517719A
Authority
BR
Brazil
Prior art keywords
transmucosal
detomidine
veterinary composition
composition
semi
Prior art date
Application number
BRPI0517719-7A
Other languages
English (en)
Inventor
Mirja Huhtinen
Piritta Koistinen
Lasse Leino
Maria Rantala
Helena Kaukinen
Ursin Kaija Af
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Publication of BRPI0517719A publication Critical patent/BRPI0517719A/pt
Publication of BRPI0517719B1 publication Critical patent/BRPI0517719B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)

Abstract

COMPOSIçãO VETERINáRIA TRANSMUCOSAL COMPREENDENDO DETOMIDINA.A presente invenção se refere a uma composição veterinária em uma formasemi-sólida adaptada para administração transmucosal para fornecer sedação e analgesia em animais de grande porte tais como cavalos e gado A composição transmucosal semi-sólida da invenção compreende detomidinaou um sal farmaceuticamente aceitável desta como um ingrediente ativo. A composição fornece um início rápido de ação enquanto tendo potencial de irritação baixo na mucosa oral.
BRPI0517719A 2004-11-05 2005-11-03 composição veterinária farmacêutica na forma de um gel transmucosal e kit veterinário BRPI0517719B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62512904P 2004-11-05 2004-11-05
FI20041425A FI20041425A0 (fi) 2004-11-05 2004-11-05 Transmukosaalinen veterinäärinen koostumus
PCT/FI2005/000470 WO2006048501A1 (en) 2004-11-05 2005-11-03 A transmucosal veterinary composition comprising detomidine

Publications (2)

Publication Number Publication Date
BRPI0517719A true BRPI0517719A (pt) 2008-10-21
BRPI0517719B1 BRPI0517719B1 (pt) 2018-11-06

Family

ID=33515193

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0517719A BRPI0517719B1 (pt) 2004-11-05 2005-11-03 composição veterinária farmacêutica na forma de um gel transmucosal e kit veterinário

Country Status (22)

Country Link
US (2) US7863311B2 (pt)
EP (1) EP1811995B1 (pt)
JP (1) JP4996472B2 (pt)
KR (1) KR101257672B1 (pt)
AR (1) AR054987A1 (pt)
AU (1) AU2005300451B2 (pt)
BR (1) BRPI0517719B1 (pt)
CA (1) CA2583876C (pt)
DK (1) DK1811995T3 (pt)
ES (1) ES2388442T3 (pt)
FI (1) FI20041425A0 (pt)
HR (1) HRP20120856T1 (pt)
IL (1) IL182541A (pt)
MX (1) MX2007005238A (pt)
NO (1) NO338158B1 (pt)
NZ (1) NZ554521A (pt)
PL (1) PL1811995T3 (pt)
PT (1) PT1811995E (pt)
RS (1) RS52504B (pt)
SI (1) SI1811995T1 (pt)
WO (1) WO2006048501A1 (pt)
ZA (1) ZA200703486B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100784134B1 (ko) 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
EP2061440A2 (en) * 2007-04-04 2009-05-27 Sigmoid Pharma Limited A pharmaceutical composition of tacrolimus
US20090246256A1 (en) * 2008-03-27 2009-10-01 Al-Ghananeem Abeer M Compositions and Methods for Transmucosal Delivery of Lofexidine
KR101517415B1 (ko) 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물
CN102596151B (zh) * 2009-09-04 2014-04-30 株式会社资生堂 O/w乳化组合物的制备方法
WO2012106058A2 (en) 2011-01-31 2012-08-09 New Market Pharmaceuticals Animal treatments
EP3505159B1 (en) 2012-05-02 2020-11-04 NewMarket Pharmaceuticals LLC Pharmaceutical compositions for direct systemic introduction
US10064849B2 (en) 2012-05-02 2018-09-04 New Market Pharmaceuticals Pharmaceutical compositions for direct systemic introduction
FR2990134B1 (fr) * 2012-05-07 2014-11-21 Anaconda Pharma Composition pharmaceutique d'un inhibiteur du virus du papillome
MX368880B (es) * 2012-10-15 2019-10-21 Orion Corp Dexmedetomidina y medetomidina para su uso en el alivio de la aversión al ruido en un animal.
EA201591187A1 (ru) * 2012-12-21 2016-03-31 Тева Фармасьютикал Индастриз Лтд. Пероральная трансмукозальная доставка ацетата глатирамера
FI127534B (en) * 2014-11-10 2018-08-31 Vetcare Oy Substituted benzoefuroquinolizine and ɑ2-adrenergic agonist comprising compositions
ES2982022T3 (es) * 2017-01-06 2024-10-14 Clexio Biosciences Ltd Formulaciones tópicas de detomidina
US20210137830A1 (en) * 2018-07-11 2021-05-13 Clexio Biosciences Ltd. Topical detomidine formulations
KR20220002950A (ko) 2019-05-01 2022-01-07 클렉시오 바이오사이언시스 리미티드 소양증의 치료 방법
US12589095B2 (en) * 2019-05-31 2026-03-31 Primo Pharmatech Llc Unit dosage form for transmucosal drug delivery of an active pharmaceutical ingredient

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
FI844786A0 (fi) * 1984-12-04 1984-12-04 Farmos Oy Terapeutiskt utnyttjbar foerening.
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
GB2256135B (en) * 1991-05-31 1995-01-18 Orion Yhtymae Oy Transdermal administration of 4-substituted imidazoles
MX9304075A (es) * 1992-07-08 1994-04-29 Applied Research Systems Composicion farmaceutica para el tratamiento o profilaxis de los desordenes trombohemorragicos consuntivos.
CN1106259A (zh) * 1994-02-05 1995-08-09 日东制药株式会社 含有作为有效成分的丙酸类非类固醇性药物的新颖消炎镇痛外用凝胶制剂
DE69833000T2 (de) 1997-09-26 2006-09-07 Noven Pharmaceuticals, Inc., Miami Bio-klebemittelzusammensetzungen
ES2228125T3 (es) * 1998-10-02 2005-04-01 3M Innovative Properties Company Sistemas de suministro de farmacos originados en las mucosas.
US7001609B1 (en) * 1998-10-02 2006-02-21 Regents Of The University Of Minnesota Mucosal originated drug delivery systems and animal applications
CA2418135C (en) 2000-08-03 2011-09-20 Antares Pharma Ipl Ag Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels
JP4493203B2 (ja) 2000-12-12 2010-06-30 株式会社ブリヂストン 空気入りタイヤの製造方法
DE10107659B4 (de) * 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin
DE10256774A1 (de) * 2002-12-05 2004-06-24 Lts Lohmann Therapie-Systeme Ag Transmucosale und transdermale Arzneimittel mit verbesserter Wirkstoffresorption

Also Published As

Publication number Publication date
EP1811995A1 (en) 2007-08-01
US20070299121A1 (en) 2007-12-27
IL182541A0 (en) 2007-09-20
FI20041425A0 (fi) 2004-11-05
MX2007005238A (es) 2007-07-09
NZ554521A (en) 2010-09-30
US8309591B2 (en) 2012-11-13
AR054987A1 (es) 2007-08-01
AU2005300451A1 (en) 2006-05-11
NO338158B1 (no) 2016-08-01
IL182541A (en) 2011-02-28
NO20072864L (no) 2007-06-05
CA2583876C (en) 2012-05-29
HRP20120856T1 (hr) 2012-11-30
KR20070085284A (ko) 2007-08-27
KR101257672B1 (ko) 2013-04-24
CA2583876A1 (en) 2006-05-11
WO2006048501A1 (en) 2006-05-11
JP4996472B2 (ja) 2012-08-08
DK1811995T3 (da) 2012-08-20
AU2005300451B2 (en) 2011-01-20
EP1811995B1 (en) 2012-07-25
RS52504B (sr) 2013-04-30
BRPI0517719B1 (pt) 2018-11-06
JP2008519012A (ja) 2008-06-05
ES2388442T3 (es) 2012-10-15
ZA200703486B (en) 2008-06-25
SI1811995T1 (sl) 2012-10-30
US20110071203A1 (en) 2011-03-24
US7863311B2 (en) 2011-01-04
PL1811995T3 (pl) 2012-12-31
PT1811995E (pt) 2012-08-03

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.

B08G Application fees: restoration [chapter 8.7 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07C Technical examination (opinion): republication [chapter 7.3 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 06/11/2018, OBSERVADAS AS CONDICOES LEGAIS.