BRPI0517883B8 - complexos de fosfato de cálcio estabilizado - Google Patents

complexos de fosfato de cálcio estabilizado Download PDF

Info

Publication number
BRPI0517883B8
BRPI0517883B8 BRPI0517883A BRPI0517883A BRPI0517883B8 BR PI0517883 B8 BRPI0517883 B8 BR PI0517883B8 BR PI0517883 A BRPI0517883 A BR PI0517883A BR PI0517883 A BRPI0517883 A BR PI0517883A BR PI0517883 B8 BRPI0517883 B8 BR PI0517883B8
Authority
BR
Brazil
Prior art keywords
calcium phosphate
complexes
stabilized calcium
phosphate complexes
stabilized
Prior art date
Application number
BRPI0517883A
Other languages
English (en)
Inventor
Charles Reynolds Eric
Original Assignee
Univ Melbourne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2004906762A external-priority patent/AU2004906762A0/en
Application filed by Univ Melbourne filed Critical Univ Melbourne
Publication of BRPI0517883A publication Critical patent/BRPI0517883A/pt
Publication of BRPI0517883B1 publication Critical patent/BRPI0517883B1/pt
Publication of BRPI0517883B8 publication Critical patent/BRPI0517883B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

complexos de fosfato de cálcio estabilizado. a presente invenção refere-se a um complexo de fosfato de cálcio amorfo e/ou fosfato de fluoreto de cálcio amorfo estabilizado por fosfopeptídeos, onde o complexo é formado em um ph abaixo de 7,0. os métodos para a preparação de tais complexos são também fornecidos. os complexos são úteis em aparelhos dentários, em particular em remineralização dentária.
BRPI0517883A 2004-11-25 2005-11-24 complexos de fosfato de cálcio estabilizado BRPI0517883B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2004906762A AU2004906762A0 (en) 2004-11-25 Stabilized calcium phosphate complexes
AU2004906762 2004-11-25
PCT/AU2005/001781 WO2006056013A1 (en) 2004-11-25 2005-11-24 Stabilized calcium phosphate complexes

Publications (3)

Publication Number Publication Date
BRPI0517883A BRPI0517883A (pt) 2008-10-21
BRPI0517883B1 BRPI0517883B1 (pt) 2015-06-23
BRPI0517883B8 true BRPI0517883B8 (pt) 2020-03-24

Family

ID=36497671

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0517883A BRPI0517883B8 (pt) 2004-11-25 2005-11-24 complexos de fosfato de cálcio estabilizado

Country Status (12)

Country Link
US (3) US8609071B2 (pt)
EP (2) EP3192489A1 (pt)
JP (1) JP5000525B2 (pt)
CN (1) CN101098675B (pt)
AU (1) AU2005309327B2 (pt)
BR (1) BRPI0517883B8 (pt)
CA (1) CA2589270C (pt)
MX (1) MX2007006254A (pt)
NZ (1) NZ555335A (pt)
PL (1) PL1827366T3 (pt)
RU (1) RU2404738C2 (pt)
WO (1) WO2006056013A1 (pt)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2705826B1 (en) * 2006-02-09 2019-09-11 The University of Melbourne Fluoride composition and methods for dental mineralization
CN101415398B (zh) 2006-04-05 2013-01-09 卡夫食品环球品牌有限责任公司 口腔递送系统中的磷酸钙复合物和盐
AU2007235445B2 (en) 2006-04-05 2011-04-14 Intercontinental Great Brands Llc Calcium phosphate complex in acid containing confectionery
ES2619161T3 (es) 2006-04-05 2017-06-23 Intercontinental Great Brands Llc Complejo de fosfato de calcio y sales en sistemas de suministro oral
CA2965384C (en) 2007-08-09 2021-06-22 The Board Of Regents Of The University Of Texas System Bi-layered bone-like scaffolds
BRPI0915885A2 (pt) * 2008-07-09 2015-11-03 Univ Nebraska micelas funcionais para a liberação direcionada de substâncias químicas em tecido duro
JP2010047494A (ja) * 2008-08-20 2010-03-04 Gc Corp 歯牙塗布用組成物
AU2011250934B2 (en) * 2010-05-11 2016-02-25 Howmedica Osteonics Corp., Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods
US20140161852A1 (en) * 2011-04-20 2014-06-12 University Of Rochester Nanoparticle dental composition and method of making
JP2013163656A (ja) * 2012-02-10 2013-08-22 Gc Corp 歯磨剤
US9744108B2 (en) 2013-02-28 2017-08-29 University Of Tennessee Research Foundation Methods and compositions for preventing and treating tooth erosion
US10314771B2 (en) 2013-02-28 2019-06-11 University Of Tennessee Research Foundation Methods and compositions for preventing and treating tooth erosion
MX378581B (es) * 2013-07-23 2025-03-10 Univ Melbourne Composiciones y metodos para la mineralizacion dental.
WO2015023773A2 (en) 2013-08-14 2015-02-19 University Of Tennessee Research Foundation Tooth remineralization compositions and methods
EP3049054B1 (en) 2013-09-25 2018-04-04 Credentis AG Dental care product for tooth whitening
EP2853256A1 (en) 2013-09-25 2015-04-01 Credentis AG Dental care product for tooth whitening
US9168114B2 (en) 2013-10-17 2015-10-27 B & D Dental Corp. Method of making a dental prosthesis
ES2959412T3 (es) 2013-12-24 2024-02-26 Univ Melbourne Composiciones estañosas estabilizadas
JP6751027B2 (ja) * 2014-07-11 2020-09-02 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 非晶質リン酸カルシウムを供給する口腔ケア処方システム
EP3174409A4 (en) 2014-07-31 2018-01-17 Amorphical Ltd. Encapsulated amorphous calcium carbonate compositions
JP2016102069A (ja) * 2014-11-27 2016-06-02 株式会社ジーシー 歯面清掃方法、歯面清掃用組成物、及びその使用方法
CN107427700A (zh) * 2014-12-24 2017-12-01 墨尔本大学 矿化氟化物组合物
US10219986B2 (en) 2015-03-04 2019-03-05 Modern Ideas LLC Stabilized calcium phosphate and methods of forming same
MX2018005200A (es) * 2015-10-26 2018-07-06 Basf Se Productos para el cuidado bucal y procedimientos que comprenden polipeptidos de union a hidroxiapatita (habp).
US9956314B2 (en) 2016-01-26 2018-05-01 Modern Ideas LLC Adhesive for use with bone and bone-like structures
BR112018074268B1 (pt) 2016-05-26 2022-04-19 3M Innovative Properties Company Pasta dental, kit para tratamento de uma superfície na cavidade oral de um indivíduo, e uso
US12109284B2 (en) 2016-11-08 2024-10-08 Dentherapy Ltd Compositions comprising fluoride and calcium and method for preparing them
EA201991935A1 (ru) 2017-03-14 2020-02-14 Де Юниверсити Оф Мельбурн Комплексы для лечения чувствительности
EA201991933A1 (ru) 2017-03-14 2020-03-05 Де Юниверсити Оф Мельбурн Лечение гингивита
US12569417B2 (en) 2019-03-13 2026-03-10 The University Of Melbourne Compositions and methods for promoting mineralization
JP7546615B2 (ja) * 2019-07-04 2024-09-06 ファートン ホールディング エス．アー． 歯の再石灰化のための組成物
CN110483622B (zh) * 2019-08-26 2021-06-11 无限极（中国）有限公司 酪蛋白磷酸肽及其制备方法、应用
US11154470B1 (en) 2020-07-31 2021-10-26 vVardis AG Anti-inflammatory and senolytic dental care product with tooth whitening characteristics
EP3984517A1 (en) 2020-10-19 2022-04-20 Credentis AG Accelerating tooth remineralisation and bone regeneration with self-assembling peptides and amorphous calcium phosphate
CN112499607B (zh) * 2020-10-29 2022-07-26 南京师范大学 用于多磷酸肽富集及磷酸化位点鉴定的纳米磷酸钙的制备方法及其产品和应用
GB202110114D0 (en) 2021-07-14 2021-08-25 Dentherapy Ltd Oral care compositions for use in treaatment
CN114343060B (zh) * 2021-12-30 2023-07-25 河南金丹乳酸科技股份有限公司 一种乳酸生产中提高菌体渣中蛋白含量的工艺
EP4608356A1 (en) 2022-10-28 2025-09-03 Queen Mary University of London Toothpaste composition

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522805A (en) * 1983-06-08 1985-06-11 Norman Gordon Tooth and gum dentifrice
CA1315480C (en) 1986-06-12 1993-03-30 Eric Charles Reynolds Phosphopeptides
US5015628A (en) 1986-06-12 1991-05-14 The University Of Melbourne Anticariogenic phosphopeptides
US6056930A (en) * 1989-05-24 2000-05-02 American Dental Association Health Foundation Methods and compositions for mineralizing and fluoridating calcified tissues
US5227154A (en) 1991-08-22 1993-07-13 The University Of Melbourne Phosphopeptides for the treatment of dental calculus
KR100238551B1 (ko) 1992-06-29 2000-02-01 도우글라스 웨이르 민감성 치아 치료
JP3340265B2 (ja) 1994-11-21 2002-11-05 一枝 山岸 歯の漂白剤
JP4040705B2 (ja) 1996-01-24 2008-01-30 株式会社サンギ 口腔組成物
JP2975337B2 (ja) 1997-02-20 1999-11-10 雪印乳業株式会社 カルシウム複合体
AUPO566297A0 (en) * 1997-03-13 1997-04-10 University Of Melbourne, The Calcium phosphopeptide complexes
JP3742523B2 (ja) * 1998-02-27 2006-02-08 雪印乳業株式会社 高分子型カルシウム・ホスホペプチド複合体
WO2000057842A2 (en) * 1999-03-25 2000-10-05 Warner-Lambert Company Oral care chewing gums and confections
FR2791573B1 (fr) 1999-03-30 2003-04-11 Pf Medicament Utilisation d'un extrait de serenoa repens pour la fabrication d'un medicament destine au traitement du cancer de la prostate
US6521215B2 (en) * 1999-05-28 2003-02-18 Devin Okay Compositions and methods for tooth treatment
US6685920B2 (en) 1999-11-12 2004-02-03 The Procter & Gamble Company Method of protecting teeth against erosion
GB9929919D0 (en) 1999-12-17 2000-02-09 Hannah Research Inst The Calcium phosphate nanoclusters and their applications
RU2179420C2 (ru) * 2000-05-26 2002-02-20 Иркутский государственный медицинский университет Способ профилактики кариеса зубов
JP2002338447A (ja) 2001-05-15 2002-11-27 Kuraray Co Ltd 歯科用組成物
AUPR517701A0 (en) * 2001-05-21 2001-06-14 University Of Melbourne, The Dental restorative materials
MXPA04006542A (es) * 2002-01-03 2004-10-04 Procter & Gamble Composiciones bucales estables que contienen complejos de fosfopeptido de caseina y fluooruro.
CA2469498C (en) * 2002-01-03 2009-06-02 The Procter & Gamble Company Stable oral compositions comprising casein phosphopeptide complexes and fluoride
NZ522071A (en) 2002-10-18 2005-07-29 Patrick Joseph Silcock Hydrolysed casein phosphoprotein preparations for bioactive metal ion delivery and teeth remineralisation
JP4340069B2 (ja) * 2003-01-10 2009-10-07 雪印乳業株式会社 カルシウム複合体の製造法
US20050089481A1 (en) 2003-10-23 2005-04-28 Gc Corporation Composition for caries prevention
US20060183081A1 (en) 2004-09-27 2006-08-17 Al Bevilacqua Tooth bleaching system and method
AR057353A1 (es) 2005-06-07 2007-11-28 Univ Melbourne Mineralizacion dental
AR057402A1 (es) 2005-06-24 2007-12-05 Univ Melbourne Complejos de fosfato de calcio estabilizados por fosfopeptidos o fosfoproteinas, proceso de obtencion y composiciones farmaceuticas

Also Published As

Publication number Publication date
AU2005309327B2 (en) 2010-11-25
MX2007006254A (es) 2007-09-07
BRPI0517883B1 (pt) 2015-06-23
US9814662B2 (en) 2017-11-14
EP1827366A1 (en) 2007-09-05
CN101098675B (zh) 2013-04-10
CN101098675A (zh) 2008-01-02
US20140079650A1 (en) 2014-03-20
BRPI0517883A (pt) 2008-10-21
CA2589270C (en) 2014-07-15
AU2005309327A1 (en) 2006-06-01
RU2007123603A (ru) 2008-12-27
NZ555335A (en) 2010-10-29
PL1827366T3 (pl) 2017-10-31
US20080075675A1 (en) 2008-03-27
US8609071B2 (en) 2013-12-17
EP3192489A1 (en) 2017-07-19
US9295628B2 (en) 2016-03-29
JP2008521754A (ja) 2008-06-26
JP5000525B2 (ja) 2012-08-15
US20160175226A1 (en) 2016-06-23
EP1827366A4 (en) 2010-05-26
EP1827366B1 (en) 2017-03-15
CA2589270A1 (en) 2006-06-01
WO2006056013A1 (en) 2006-06-01
RU2404738C2 (ru) 2010-11-27

Similar Documents

Publication Publication Date Title
BRPI0517883B8 (pt) complexos de fosfato de cálcio estabilizado
IS7728A (is) Aðferð til að framleiða kalsíumsalt rósuvastatíns
BR0111750A (pt) Método para melhorar a atividade de um sal de alumìnio ou um sal de alumìnio/zircÈnio, sal melhorado obtido pelo mesmo, e, produto antiperspirante e/ou desodorante anidro produzido com um sal melhorado
ATE554722T1 (de) System zur bereitstellung zahnärztlicher vorrichtungen in einer sequenz
MA27933A1 (fr) Inhibiteurs de l'activite de akt
EA200501333A1 (ru) 5,7-ДИАМИНОПИРАЗОЛО[4,3-d]ПИРИМИДИНЫ, ПОЛЕЗНЫЕ ПРИ ЛЕЧЕНИИ ГИПЕРТЕНЗИИ
KR100642961B9 (ko) 골다공증 치료 및 예방용 비스포스폰산
WO2006055329A3 (en) Dental fillers including a phosphorus-containing surface treatment
NO20072290L (no) Organiske forbindelser.
BRPI0506662A (pt) composto
AR059440A1 (es) Composiciones con fluoruro y metodos para la mineralizacion dental
WO2005032471A3 (en) Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease
DE50212935D1 (de) Organo-phosphorverbindungen zur aktivierung von gamma/delta-t-zellen
TW200621745A (en) Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents
ATE427356T1 (de) Komplementinhibitoren aus zecken
MX2009008303A (es) Productos para el cuidado oral que comprenden sistemas regulador de ph para beneficios de mineralizacion/reminerizacion mejorados.
DE50307886D1 (de) Leitungsführungseinheit zur aktiven führung von leitungen, kabeln oder dergleichen
WO2003091186A3 (en) Azasilanes and methods for making and using the same
BRPI0406596A (pt) Métodos para tratar a dor articular e melhorar o sono utilizando um agonista/antagonista de estrogênio
ATE408022T1 (de) Ermittlung des patientenbezogenen kariesrisikos
ATE336226T1 (de) Haarbehandlungszusammensetzungen mit xanthin und alpha-hydroxysäure
NO20054898L (no) Forbindelser med nootropisk virkning, deres fremstilling, farmasoytiske sammensetninger som inneholder disse samt deres anvendelse
BRPI0506718A (pt) compostos, processo de preparação dos mesmos, e, composição farmacêutica ou cosmética
EP1767541A4 (en) HLA-A24 OR HLA-A2 BINDING PEPTIDE OF THE PARATHYROID HORMONE-RELATED PROTEIN
BRPI0409195A (pt) sal de alumìnio e/ou zircÈnio isento de glicina com betaìna, produto antiperspirante e/ou desodorante, antiperspirantes e/ou desodorantes em bastão, com rolete, sólido mole, e em gel, e, processo para fabricar o sal

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/11/2005, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REF. RPI 2320 DE 23/06/2015 QUANTO AO INVENTOR.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 24/11/2025