BRPI0518239A2 - composiÇÕes farmacÊuticas espontaneamente dispersÍveis - Google Patents

composiÇÕes farmacÊuticas espontaneamente dispersÍveis

Info

Publication number
BRPI0518239A2
BRPI0518239A2 BRPI0518239-5A BRPI0518239A BRPI0518239A2 BR PI0518239 A2 BRPI0518239 A2 BR PI0518239A2 BR PI0518239 A BRPI0518239 A BR PI0518239A BR PI0518239 A2 BRPI0518239 A2 BR PI0518239A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
solid
spontaneously dispersible
dispersible pharmaceutical
room temperature
Prior art date
Application number
BRPI0518239-5A
Other languages
English (en)
Inventor
Ping Li
Madhusudhan Pudipeddi
Alan Edward Royce
Sara Royce Hynes
Abu T M Serajuddin
Barbara Lueckel
Michael Ambuehl
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0518239A2 publication Critical patent/BRPI0518239A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

COMPOSIÇÕES FARMACÊUTICAS ESPONTANEAMENTE DISPERSíVEIS. A presente invenção refere-se a uma composição farmacêutica espontaneamente díspersivel compreendendo uma droga fracamente solú- vel e um meio de portador compreendendo (1) um componente lípofihico, (2) um tensoativo, e opcíonalmente (3) um componente hidrofilico, em que pelo menos um dos componentes (1) a (3) é sólido em temperatura ambiente Um componente hídrofilico partícularmente útil no sistema é um polimero que é sólido em temperatura ambiente, por exemplo, sólido PEG.
BRPI0518239-5A 2004-10-29 2005-10-27 composiÇÕes farmacÊuticas espontaneamente dispersÍveis BRPI0518239A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62334504P 2004-10-29 2004-10-29
US62334404P 2004-10-29 2004-10-29
PCT/US2005/039004 WO2006050123A1 (en) 2004-10-29 2005-10-27 Spontaneously dispersible pharmaceutical compositions

Publications (1)

Publication Number Publication Date
BRPI0518239A2 true BRPI0518239A2 (pt) 2008-11-11

Family

ID=35876536

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0518239-5A BRPI0518239A2 (pt) 2004-10-29 2005-10-27 composiÇÕes farmacÊuticas espontaneamente dispersÍveis

Country Status (9)

Country Link
US (1) US20080064760A1 (pt)
EP (1) EP1807049A1 (pt)
JP (1) JP2008518931A (pt)
KR (1) KR20070069172A (pt)
AU (1) AU2005302501A1 (pt)
BR (1) BRPI0518239A2 (pt)
CA (1) CA2578854A1 (pt)
MX (1) MX2007005124A (pt)
WO (1) WO2006050123A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100008998A1 (en) * 2006-09-26 2010-01-14 Samyang Corporation Submicron nanoparticle of poorly water soluble camptothecin derivatives and process for preparation thereof
MX2009005947A (es) * 2006-12-05 2009-06-17 Novartis Ag Formas de dosificacion en microemulsion de valsartan, y metodos para elaborarlas.
WO2008092084A2 (en) 2007-01-26 2008-07-31 Centocor, Inc. Injectable non-aqueous suspension with high concentration of therapeutic agent
US10842770B2 (en) 2010-05-03 2020-11-24 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
NZ337316A (en) * 1997-03-12 2001-06-29 Abbott Lab Hydrophilic binary systems comprising cyclosporine, hydrophilic phase and a surfactant for the administration of cyclosporine
ID25908A (id) * 1998-03-06 2000-11-09 Novartis Ag Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
US20020102301A1 (en) * 2000-01-13 2002-08-01 Joseph Schwarz Pharmaceutical solid self-emulsifying composition for sustained delivery of biologically active compounds and the process for preparation thereof
US6828301B2 (en) * 2002-02-07 2004-12-07 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for hepatitis C viral protease inhibitors
AU2003295773A1 (en) * 2002-11-21 2004-06-18 Novacea, Inc. Treatment of liver disease with active vitamin d compounds

Also Published As

Publication number Publication date
MX2007005124A (es) 2007-06-22
CA2578854A1 (en) 2006-05-11
AU2005302501A1 (en) 2006-05-11
WO2006050123A1 (en) 2006-05-11
KR20070069172A (ko) 2007-07-02
JP2008518931A (ja) 2008-06-05
EP1807049A1 (en) 2007-07-18
US20080064760A1 (en) 2008-03-13

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.