BRPI0519242A2 - uso derivados de 1-aminociclohexano para o tratamento de esclerose méltipla, instabilidade emocional e paralisia pseudobulbar - Google Patents

uso derivados de 1-aminociclohexano para o tratamento de esclerose méltipla, instabilidade emocional e paralisia pseudobulbar

Info

Publication number
BRPI0519242A2
BRPI0519242A2 BRPI0519242-0A BRPI0519242A BRPI0519242A2 BR PI0519242 A2 BRPI0519242 A2 BR PI0519242A2 BR PI0519242 A BRPI0519242 A BR PI0519242A BR PI0519242 A2 BRPI0519242 A2 BR PI0519242A2
Authority
BR
Brazil
Prior art keywords
treatment
multiple sclerosis
emotional instability
pseudobulbar paralysis
aminocyclohexane derivatives
Prior art date
Application number
BRPI0519242-0A
Other languages
English (en)
Inventor
Jeffrey Jonas
Allison Mann
Wojciech Danysz
Christopher Graham Raphael Parsons
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of BRPI0519242A2 publication Critical patent/BRPI0519242A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

USO DE DERIVADOS DE l-AMINOCICLOHEXANO PARA O TRATAMENTO DE ESCLEROSE MéLTIPLA, INSTABILIDADE EMOCIONAL E PARALISIA PSEUDOBULBAR. A presente invenção relaciona-se ao tratamento de indivíduos diagnosticados com esclerose múltipla, instabilidade emocional ou paralisia pseudobulbar que compreende a administração ao referido individual de uma quantidade eficaz.de um derivado de l-aminociclohexano, ou seja, especialmente memantina ou neramexano.
BRPI0519242-0A 2004-12-22 2005-12-22 uso derivados de 1-aminociclohexano para o tratamento de esclerose méltipla, instabilidade emocional e paralisia pseudobulbar BRPI0519242A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63842304P 2004-12-22 2004-12-22
PCT/US2005/046733 WO2006069294A1 (en) 2004-12-22 2005-12-22 1-aminocyclohexane-derivatives for the treatment of multiple sclerosis emotional lability and pseudobulbar affect

Publications (1)

Publication Number Publication Date
BRPI0519242A2 true BRPI0519242A2 (pt) 2009-01-06

Family

ID=36084339

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0519242-0A BRPI0519242A2 (pt) 2004-12-22 2005-12-22 uso derivados de 1-aminociclohexano para o tratamento de esclerose méltipla, instabilidade emocional e paralisia pseudobulbar

Country Status (13)

Country Link
US (2) US20060205822A1 (pt)
EP (1) EP1838297A1 (pt)
JP (1) JP2008525488A (pt)
KR (1) KR20070086507A (pt)
CN (1) CN101087599A (pt)
AU (1) AU2005319078A1 (pt)
BR (1) BRPI0519242A2 (pt)
CA (1) CA2589671A1 (pt)
EA (1) EA200701351A1 (pt)
IL (1) IL183963A0 (pt)
MX (1) MX2007007416A (pt)
WO (1) WO2006069294A1 (pt)
ZA (1) ZA200705112B (pt)

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EA201290860A1 (ru) * 2010-03-03 2013-04-30 Тева Фармасьютикал Индастриз Лтд. Лечение ревматоидного артрита комбинацией лаквинимода и метотрексата
WO2012048871A1 (en) * 2010-10-12 2012-04-19 Merz Pharma Gmbh & Co. Kgaa Memantine for improving cognitive performance in subjects
AU2011328993B2 (en) 2010-11-15 2017-03-02 Agenebio, Inc. Pyridazine derivatives, compositions and methods for treating cognitive impairment
PE20140872A1 (es) * 2010-12-07 2014-08-09 Teva Pharma Uso de laquinimod para reducir la fatiga, mejorar el estado funcional y mejorar la calidad de vida en pacientes con esclerosis multiple
CN102241678B (zh) 2011-04-26 2014-10-29 辽宁利锋科技开发有限公司 含有脂环结构化合物的抗肿瘤作用与应用
SG11201401330YA (en) 2011-10-12 2014-05-29 Teva Pharma Treatment of multiple sclerosis with combination of laquinimod and fingolimod
WO2013116657A1 (en) 2012-02-03 2013-08-08 Teva Pharmaceutical Industries Ltd. USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNFα THERAPY
TW201400117A (zh) 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
EA201591187A1 (ru) * 2012-12-21 2016-03-31 Тева Фармасьютикал Индастриз Лтд. Пероральная трансмукозальная доставка ацетата глатирамера
TWI508461B (zh) * 2013-01-04 2015-11-11 Mstar Semiconductor Inc 適用於數位電視廣播系統的信號處理方法以及接收器
EP4032889B1 (en) 2013-12-20 2026-05-06 Agenebio, Inc. Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
HK1231413A1 (zh) 2014-04-29 2017-12-22 Teva Pharmaceutical Industries Ltd. 用於治疗具有高残疾状况的复发-缓解型多发性硬化症(rrms)的患者的拉喹莫德
EP3310785B1 (en) 2015-06-19 2024-11-20 Agenebio, Inc. Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
US10835499B2 (en) 2015-12-30 2020-11-17 Corium, Inc. Systems and methods for long term transdermal administration
CN109922796B (zh) 2016-06-23 2023-04-07 考里安有限责任公司 具有亲水和疏水域的粘合剂基质和治疗剂
KR102424270B1 (ko) 2016-07-27 2022-07-25 코리움, 인크. 경구 전달과 생물학적으로 동등한 약물동역학을 가진 경피 전달 시스템
EP3490544A1 (en) 2016-07-27 2019-06-05 Corium International, Inc. Memantine transdermal delivery systems
JP7071330B2 (ja) 2016-07-27 2022-05-18 コリウム， インコーポレイテッド 炭酸水素ナトリウムのｉｎ ｓｉｔｕ変換で促進されたアミン薬物の経皮送達
US20180170941A1 (en) 2016-12-19 2018-06-21 Agenebio, Inc. Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
WO2019126531A1 (en) 2017-12-20 2019-06-27 Corium, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point
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Also Published As

Publication number Publication date
CA2589671A1 (en) 2006-06-29
ZA200705112B (en) 2008-10-29
US20090081259A1 (en) 2009-03-26
KR20070086507A (ko) 2007-08-27
IL183963A0 (en) 2008-12-29
MX2007007416A (es) 2007-08-15
CN101087599A (zh) 2007-12-12
JP2008525488A (ja) 2008-07-17
AU2005319078A1 (en) 2006-06-29
US20060205822A1 (en) 2006-09-14
EP1838297A1 (en) 2007-10-03
EA200701351A1 (ru) 2007-12-28
WO2006069294A1 (en) 2006-06-29

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.