BRPI0519574A2 - processo para preparar Ácido 2-oxo-4-metiltiobutÍrico e seus sais, processo para preparar composto, processo para preparar Ácido 2-oxo-but-3-enàico (iii), complemento alimentar, raÇço alimentar, processo de administraÇço de metionina biodisponÍvel a uma vaca, utilizaÇço de composto e de seus sais - Google Patents
processo para preparar Ácido 2-oxo-4-metiltiobutÍrico e seus sais, processo para preparar composto, processo para preparar Ácido 2-oxo-but-3-enàico (iii), complemento alimentar, raÇço alimentar, processo de administraÇço de metionina biodisponÍvel a uma vaca, utilizaÇço de composto e de seus saisInfo
- Publication number
- BRPI0519574A2 BRPI0519574A2 BRPI0519574-8A BRPI0519574A BRPI0519574A2 BR PI0519574 A2 BRPI0519574 A2 BR PI0519574A2 BR PI0519574 A BRPI0519574 A BR PI0519574A BR PI0519574 A2 BRPI0519574 A2 BR PI0519574A2
- Authority
- BR
- Brazil
- Prior art keywords
- oxo
- preparing
- salts
- acid
- iii
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 7
- 150000003839 salts Chemical class 0.000 title abstract 4
- YYTDBCBJZXAWIC-UHFFFAOYSA-N 2-oxopentanethioic s-acid Chemical compound CCCC(=O)C(S)=O YYTDBCBJZXAWIC-UHFFFAOYSA-N 0.000 title abstract 3
- 239000002253 acid Substances 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 235000015872 dietary supplement Nutrition 0.000 title abstract 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 title 1
- 239000002361 compost Substances 0.000 title 1
- 229930182817 methionine Natural products 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- DGUBLKUCHAAUFT-UHFFFAOYSA-N 2-oxobut-3-enoic acid Chemical compound OC(=O)C(=O)C=C DGUBLKUCHAAUFT-UHFFFAOYSA-N 0.000 abstract 2
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 235000019728 animal nutrition Nutrition 0.000 abstract 1
- ITMIAZBRRZANGB-UHFFFAOYSA-N but-3-ene-1,2-diol Chemical compound OCC(O)C=C ITMIAZBRRZANGB-UHFFFAOYSA-N 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
- C07C51/21—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen
- C07C51/23—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups
- C07C51/245—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups of keto groups or secondary alcohol groups
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/18—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by addition of thiols to unsaturated compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
PROCESSO PARA PREPARAR ÁCIDO 2-OXO-4 METILTIOBUTÍRICO E SEUS SAIS, PROCESSO PARA PREPARAR COMPOSTO, PROCESSO PARA PREPARAR ÁCIDO 2-OXO-BUT-3-ENàICO (III), COMPLEMENTO ALIMENTAR, RAÇçO ALIMENTAR, PROCESSO DE ADMINISTRAÇçO DE METIONINA BIODISPONÍVEL A UMA VACA, UTILIZAÇçO DE COMPOSTO E DE SEUS SAIS A presente invenção refere-se a um processo para preparar o ácido 2-oxo-4-metiltiobutírico (1), seus sais e seus derivados de fórmula (1), na qual R representa um grupo escolhido dentre COOH, COOR', NH~ 2~, NHR', NR'R", onde R' e R" são escolhidos, independentemente um do outro, do grupo dos radicais alquil lineares ou ramificados com 1 a 12 átomos de carbono, e dos radicais cicloalquil com 3 a 12 átomos de carbono, processo segundo o qual se efetua a oxidação catalitica e seletiva do but-3-eno-1,2-diol (II) em ácido 2- oxo-but-3-enóico (III) e se condensa seletivamente a metilmercaptana sobre o ácido 2-oxo-but-3-enóico (III). O ácido 2-oxo-4-metiltiobutírico, seus sais e seus derivados são usados como complemento alimentar, sobretudo para nutrição animal.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0414084A FR2880345A1 (fr) | 2004-12-30 | 2004-12-30 | Synthese et applications de l'acide 2-oxo-4-methylthiobutyrique, ses tels et ses derives |
| PCT/FR2005/003300 WO2006072711A1 (fr) | 2004-12-30 | 2005-12-29 | Synthese et applications de l'acide 2-oxo-4-methylthiobutyrique, ses sels et ses derives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0519574A2 true BRPI0519574A2 (pt) | 2009-01-27 |
Family
ID=35004174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0519574-8A BRPI0519574A2 (pt) | 2004-12-30 | 2005-12-29 | processo para preparar Ácido 2-oxo-4-metiltiobutÍrico e seus sais, processo para preparar composto, processo para preparar Ácido 2-oxo-but-3-enàico (iii), complemento alimentar, raÇço alimentar, processo de administraÇço de metionina biodisponÍvel a uma vaca, utilizaÇço de composto e de seus sais |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US7662997B2 (pt) |
| EP (2) | EP2229821A3 (pt) |
| JP (1) | JP2008526720A (pt) |
| KR (1) | KR20070093144A (pt) |
| CN (2) | CN101090884A (pt) |
| AR (1) | AR053112A1 (pt) |
| AT (1) | ATE472527T1 (pt) |
| AU (2) | AU2005323885B2 (pt) |
| BR (1) | BRPI0519574A2 (pt) |
| CA (1) | CA2592588A1 (pt) |
| DE (1) | DE602005022110D1 (pt) |
| ES (1) | ES2347807T3 (pt) |
| FR (1) | FR2880345A1 (pt) |
| MX (1) | MX2007008110A (pt) |
| MY (1) | MY138998A (pt) |
| NO (1) | NO20073974L (pt) |
| RU (1) | RU2385862C2 (pt) |
| SG (1) | SG158190A1 (pt) |
| TW (1) | TW200635886A (pt) |
| UA (1) | UA86848C2 (pt) |
| WO (1) | WO2006072711A1 (pt) |
| ZA (1) | ZA200704430B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006055470A1 (de) * | 2006-11-24 | 2008-05-29 | Evonik Degussa Gmbh | Ketomethioninketale und deren Derivate |
| DE102007031917A1 (de) * | 2007-07-09 | 2009-01-15 | Evonik Degussa Gmbh | Verfahren zur Herstellung von Ketosäuren und deren Derivaten |
| JP2012126651A (ja) * | 2010-12-13 | 2012-07-05 | Sumitomo Chemical Co Ltd | ヒドロキシカルボン酸化合物またはその塩の製造方法 |
| JP2012136466A (ja) * | 2010-12-27 | 2012-07-19 | Sumitomo Chemical Co Ltd | ２−オキソ−４−メチルチオブタン酸又はその塩の製造方法 |
| JP2012136467A (ja) * | 2010-12-27 | 2012-07-19 | Sumitomo Chemical Co Ltd | ２−オキソ−４−メチルチオブタン酸又はその塩の製造方法 |
| AU2012236099A1 (en) | 2011-03-31 | 2013-10-03 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| WO2014010752A1 (ja) * | 2012-07-13 | 2014-01-16 | 住友化学株式会社 | α－ヒドロキシカルボン酸エステルの製造方法 |
| EP2971165A4 (en) | 2013-03-15 | 2016-11-23 | Moderna Therapeutics Inc | DISSOLUTION OF DNA FRAGMENTS IN MRNA MANUFACTURING METHODS |
| US10590161B2 (en) | 2013-03-15 | 2020-03-17 | Modernatx, Inc. | Ion exchange purification of mRNA |
| WO2014152031A1 (en) | 2013-03-15 | 2014-09-25 | Moderna Therapeutics, Inc. | Ribonucleic acid purification |
| CA2917348A1 (en) | 2013-07-11 | 2015-01-15 | Moderna Therapeutics, Inc. | Compositions comprising synthetic polynucleotides encoding crispr related proteins and synthetic sgrnas and methods of use |
| EP3052511A4 (en) | 2013-10-02 | 2017-05-31 | Moderna Therapeutics, Inc. | Polynucleotide molecules and uses thereof |
| WO2015196128A2 (en) | 2014-06-19 | 2015-12-23 | Moderna Therapeutics, Inc. | Alternative nucleic acid molecules and uses thereof |
| US10407683B2 (en) | 2014-07-16 | 2019-09-10 | Modernatx, Inc. | Circular polynucleotides |
| FR3029518B1 (fr) * | 2014-12-05 | 2016-12-02 | Adisseo France Sas | Oxydation catalytique du but-3-ene-1,2-diol |
| WO2017049286A1 (en) | 2015-09-17 | 2017-03-23 | Moderna Therapeutics, Inc. | Polynucleotides containing a morpholino linker |
| EP3350333B2 (en) | 2015-09-17 | 2025-08-06 | ModernaTX, Inc. | Polynucleotides containing a stabilizing tail region |
| WO2017223135A1 (en) * | 2016-06-24 | 2017-12-28 | Modernatx, Inc. | Lipid nanoparticles |
| CN113845454A (zh) * | 2020-06-28 | 2021-12-28 | 张科春 | 一种酮基蛋氨酸及其衍生物的制备方法及应用 |
| JP7448153B2 (ja) * | 2020-09-08 | 2024-03-12 | 株式会社クラレ | 触媒の製造方法、及び触媒、並びに３－ヒドロキシ－３－メチルブタン酸の製造方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1449904A (fr) | 1965-07-09 | 1966-05-06 | Pechiney Saint Gobain | Agglomérés d'alumine active de résistance mécanique élevée |
| DE2531299A1 (de) * | 1975-07-12 | 1977-01-13 | Fresenius Chem Pharm Ind | L-amino- und hydroxy- und/oder ketosaeuren enthaltende gemische fuer parenterale oder orale anwendung |
| DE2836327A1 (de) * | 1978-08-19 | 1980-02-28 | Bayer Ag | Verfahren zur herstellung von arylglyoxylsaeuren |
| JPH01311045A (ja) * | 1988-06-06 | 1989-12-15 | Mitsubishi Petrochem Co Ltd | α―ケト酪酸の製造方法 |
| DE69103361T2 (de) | 1990-03-30 | 1994-12-01 | Eastman Chem Co | Verfahren zur alkohol/ester-trennung unter verwendung von geschützten hydroxylgruppen. |
| US5081096A (en) | 1990-07-25 | 1992-01-14 | Eastman Kodak Company | Epoxidation catalyst |
| US5138077A (en) | 1991-07-29 | 1992-08-11 | Eastman Kodak Company | Selective epoxidation of diolefins and aryl olefins |
| WO2000024702A1 (fr) | 1998-10-23 | 2000-05-04 | Daicel Chemical Industries, Ltd. | Procede de preparation de diesters organiques |
| AU2324000A (en) * | 1999-02-03 | 2000-08-25 | Sumitomo Chemical Company, Limited | Process for producing 2-hydroxy-4-methyl-thiobutanoic acid |
| ITTO20020672A1 (it) | 2002-07-26 | 2004-01-26 | Medestea Res And Production S | Composizioni farmaceutiche contenenti cheto-acidi per somministrazione endoperitoneale |
| JP2004131461A (ja) * | 2002-08-12 | 2004-04-30 | Idemitsu Petrochem Co Ltd | アダマンタン誘導体及びその製造方法 |
-
2004
- 2004-12-30 FR FR0414084A patent/FR2880345A1/fr not_active Withdrawn
-
2005
- 2005-12-29 SG SG200908715-6A patent/SG158190A1/en unknown
- 2005-12-29 AT AT05850628T patent/ATE472527T1/de not_active IP Right Cessation
- 2005-12-29 AU AU2005323885A patent/AU2005323885B2/en not_active Expired - Fee Related
- 2005-12-29 KR KR1020077017664A patent/KR20070093144A/ko not_active Ceased
- 2005-12-29 CN CNA2005800449804A patent/CN101090884A/zh active Pending
- 2005-12-29 AR ARP050105617A patent/AR053112A1/es unknown
- 2005-12-29 EP EP10167014A patent/EP2229821A3/fr not_active Withdrawn
- 2005-12-29 UA UAA200707269A patent/UA86848C2/ru unknown
- 2005-12-29 RU RU2007123486/04A patent/RU2385862C2/ru not_active IP Right Cessation
- 2005-12-29 MY MYPI20056266A patent/MY138998A/en unknown
- 2005-12-29 WO PCT/FR2005/003300 patent/WO2006072711A1/fr not_active Ceased
- 2005-12-29 CN CN2011100334776A patent/CN102150858A/zh active Pending
- 2005-12-29 DE DE602005022110T patent/DE602005022110D1/de not_active Expired - Lifetime
- 2005-12-29 EP EP05850628A patent/EP1831160B1/fr not_active Expired - Lifetime
- 2005-12-29 JP JP2007548869A patent/JP2008526720A/ja active Pending
- 2005-12-29 BR BRPI0519574-8A patent/BRPI0519574A2/pt not_active IP Right Cessation
- 2005-12-29 CA CA002592588A patent/CA2592588A1/fr not_active Abandoned
- 2005-12-29 US US11/792,586 patent/US7662997B2/en not_active Expired - Fee Related
- 2005-12-29 ES ES05850628T patent/ES2347807T3/es not_active Expired - Lifetime
- 2005-12-29 MX MX2007008110A patent/MX2007008110A/es active IP Right Grant
- 2005-12-30 TW TW094147849A patent/TW200635886A/zh unknown
-
2007
- 2007-05-29 ZA ZA200704430A patent/ZA200704430B/xx unknown
- 2007-07-30 NO NO20073974A patent/NO20073974L/no not_active Application Discontinuation
-
2009
- 2009-12-30 US US12/654,745 patent/US20100178380A1/en not_active Abandoned
-
2011
- 2011-01-19 AU AU2011200204A patent/AU2011200204A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2229821A3 (fr) | 2010-11-03 |
| AU2011200204A1 (en) | 2011-02-10 |
| AR053112A1 (es) | 2007-04-25 |
| TW200635886A (en) | 2006-10-16 |
| ES2347807T3 (es) | 2010-11-04 |
| US20080069920A1 (en) | 2008-03-20 |
| RU2007123486A (ru) | 2009-02-10 |
| WO2006072711A1 (fr) | 2006-07-13 |
| EP2229821A2 (fr) | 2010-09-22 |
| US7662997B2 (en) | 2010-02-16 |
| RU2385862C2 (ru) | 2010-04-10 |
| CN102150858A (zh) | 2011-08-17 |
| ATE472527T1 (de) | 2010-07-15 |
| FR2880345A1 (fr) | 2006-07-07 |
| DE602005022110D1 (de) | 2010-08-12 |
| CA2592588A1 (fr) | 2006-07-13 |
| NO20073974L (no) | 2007-07-30 |
| UA86848C2 (ru) | 2009-05-25 |
| US20100178380A1 (en) | 2010-07-15 |
| EP1831160A1 (fr) | 2007-09-12 |
| CN101090884A (zh) | 2007-12-19 |
| ZA200704430B (en) | 2008-06-25 |
| MY138998A (en) | 2009-08-28 |
| AU2005323885B2 (en) | 2010-11-18 |
| EP1831160B1 (fr) | 2010-06-30 |
| JP2008526720A (ja) | 2008-07-24 |
| KR20070093144A (ko) | 2007-09-17 |
| MX2007008110A (es) | 2007-08-21 |
| AU2005323885A1 (en) | 2006-07-13 |
| SG158190A1 (en) | 2010-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 7A, ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2203 DE 26/03/2013. |
|
| B15K | Others concerning applications: alteration of classification |
Ipc: C07C 51/245 (2006.01), A23K 20/10 (2016.01), A23K |