BRPI0520212A2 - métodos de geração de um vertebrado não humano transgênico, e de uma célula de vertebrado recombinante, célula de vertebrado em cultura, e, ácido nucleico - Google Patents

métodos de geração de um vertebrado não humano transgênico, e de uma célula de vertebrado recombinante, célula de vertebrado em cultura, e, ácido nucleico

Info

Publication number
BRPI0520212A2
BRPI0520212A2 BRPI0520212-4A BRPI0520212A BRPI0520212A2 BR PI0520212 A2 BRPI0520212 A2 BR PI0520212A2 BR PI0520212 A BRPI0520212 A BR PI0520212A BR PI0520212 A2 BRPI0520212 A2 BR PI0520212A2
Authority
BR
Brazil
Prior art keywords
vertebrate
methods
transgenic non
vertebrate cell
human
Prior art date
Application number
BRPI0520212-4A
Other languages
English (en)
Inventor
Tian Xu
Min Han
Yuan Zhuang
Xiaohui Wu
Sheng Ding
Gang Li
Original Assignee
Univ Fudan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Fudan filed Critical Univ Fudan
Publication of BRPI0520212A2 publication Critical patent/BRPI0520212A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

MéTODOS DE GERAçãO DE UM VERTEBRADO NãO HUMANO TRANSGêNICO, E DE UMA CéLULA DE VERTEBRADO RECOMBINANTE, CéLULA DE VERTEBRADO EM CULTURA, E, áCIDO NUCLEICO. A presente invenção refere-se a células de vertebrado transgênicas, incluindo mamíferos, cujos genomas compreendem um ou mais elementos do sistema transposon da família piggyBac. Os vertebrados não humanos transgênicos, incluindo mamíferos não humanos transgénicos, cujos genomas compreendem um ou mais elementos do sistema transposon da família piggyBac, são também providos. Os métodos de fazer e usar as células e animais da invenção, incluindo aplicações nos campos médico, veterinário e agrícola, são adicionalmente providos. A presente invenção também refere-se a kits utilizáveis para praticar estes métodos.
BRPI0520212-4A 2005-05-14 2005-05-14 métodos de geração de um vertebrado não humano transgênico, e de uma célula de vertebrado recombinante, célula de vertebrado em cultura, e, ácido nucleico BRPI0520212A2 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2005/000674 WO2006122442A1 (en) 2005-05-14 2005-05-14 Piggybac as a tool for genetic manipulation and analysis in vertebrates

Publications (1)

Publication Number Publication Date
BRPI0520212A2 true BRPI0520212A2 (pt) 2009-08-18

Family

ID=37430916

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0520212-4A BRPI0520212A2 (pt) 2005-05-14 2005-05-14 métodos de geração de um vertebrado não humano transgênico, e de uma célula de vertebrado recombinante, célula de vertebrado em cultura, e, ácido nucleico

Country Status (11)

Country Link
US (1) US20100154070A1 (pt)
EP (1) EP1896578A4 (pt)
JP (1) JP2008545375A (pt)
CN (1) CN101297031B (pt)
AU (1) AU2005331864A1 (pt)
BR (1) BRPI0520212A2 (pt)
CA (1) CA2608481A1 (pt)
IL (1) IL187348A0 (pt)
MX (1) MX2007014139A (pt)
NO (1) NO20076465L (pt)
WO (1) WO2006122442A1 (pt)

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US11707056B2 (en) 2013-05-02 2023-07-25 Kymab Limited Animals, repertoires and methods
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Also Published As

Publication number Publication date
CN101297031A (zh) 2008-10-29
JP2008545375A (ja) 2008-12-18
EP1896578A4 (en) 2008-11-05
EP1896578A1 (en) 2008-03-12
NO20076465L (no) 2008-02-04
CN101297031B (zh) 2013-06-05
CA2608481A1 (en) 2006-11-23
US20100154070A1 (en) 2010-06-17
AU2005331864A1 (en) 2006-11-23
IL187348A0 (en) 2008-04-13
MX2007014139A (es) 2008-10-09
WO2006122442A1 (en) 2006-11-23

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