BRPI0520252A2 - método de desacilar sucralose-6-éster - Google Patents

método de desacilar sucralose-6-éster

Info

Publication number
BRPI0520252A2
BRPI0520252A2 BRPI0520252-3A BRPI0520252A BRPI0520252A2 BR PI0520252 A2 BRPI0520252 A2 BR PI0520252A2 BR PI0520252 A BRPI0520252 A BR PI0520252A BR PI0520252 A2 BRPI0520252 A2 BR PI0520252A2
Authority
BR
Brazil
Prior art keywords
sucralose
ester
products
aqueous solution
alkaline earth
Prior art date
Application number
BRPI0520252-3A
Other languages
English (en)
Inventor
John Charles Fry
Original Assignee
Health Brands Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Brands Llc filed Critical Health Brands Llc
Publication of BRPI0520252A2 publication Critical patent/BRPI0520252A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

MéTODO DE DESACILAR SUCRALOSE-6-éSTER. A presente descrição provê um processo para produzir sucralose a partir de uma mistura de alimentação de (a) sucralose-6-éster, como 6-O-acil-4, 1 ',6'-tricloro-4, 1' ,6'-trideoxigalactosacarose, (b) sal incluindo cloreto de metal alcalino ou metal alcalino-terroso, (c) água, e (d) outros sub- produtos de sacarose clorada, em um meio de reação compreendendo uma amida terciária, em que referido processo compreende desacilar, seja antes ou após a remoção da amida terciária, a sucralose-6-éster sob resfriamento ativo para produzir uma solução aquosa compreendendo sucralose, sal incluindo cloreto de metal alcalino ou metal alcalino-terroso, e outros sub-produtos de sacarose clorada. Adicionalmente, a sucralose pode ser recuperada da solução aquosa, como por extração seguida por cristalização ou por técnicas extrativas sozinhas.
BRPI0520252-3A 2005-06-01 2005-09-28 método de desacilar sucralose-6-éster BRPI0520252A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68665405P 2005-06-01 2005-06-01
US11/237,193 US20060276639A1 (en) 2005-06-01 2005-09-27 Conversion of sucralose-6-ester to sucralose
PCT/US2005/034871 WO2006130169A1 (en) 2005-06-01 2005-09-28 Conversion of sucralose-6-ester to sucralose

Publications (1)

Publication Number Publication Date
BRPI0520252A2 true BRPI0520252A2 (pt) 2009-09-15

Family

ID=37481966

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0520252-3A BRPI0520252A2 (pt) 2005-06-01 2005-09-28 método de desacilar sucralose-6-éster

Country Status (9)

Country Link
US (1) US20060276639A1 (pt)
EP (1) EP1888609A4 (pt)
JP (1) JP2008542370A (pt)
KR (1) KR20080016896A (pt)
AU (1) AU2005332295A1 (pt)
BR (1) BRPI0520252A2 (pt)
CA (1) CA2610493A1 (pt)
IL (1) IL187818A0 (pt)
WO (1) WO2006130169A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070100139A1 (en) * 2005-10-31 2007-05-03 Healthy Brands, Llc Methods for chlorinating sucrose-6-ester
US20080227971A1 (en) * 2007-01-19 2008-09-18 Leinhos Duane A Deacylation of sucralose-6-acylates
US8436156B2 (en) * 2008-01-04 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
US8557976B2 (en) 2008-03-13 2013-10-15 Tate & Lyle Technology Limited Microbial consortia and methods for their use
WO2009117317A1 (en) * 2008-03-20 2009-09-24 Tate & Lyle Technology Ltd Removal of acids from tertiary amide solvents
US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
WO2009124113A1 (en) * 2008-04-03 2009-10-08 Tate & Lyle Technology Ltd. Extraction of less polar impurities from sucralose containing aqueous feed streams
US8212022B2 (en) * 2008-04-03 2012-07-03 Tate & Lyle Technology Limited Effect of carbohydrate concentration on sucralose extraction efficiency
US8497367B2 (en) * 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
GB2468936B (en) 2009-03-27 2011-09-07 Mohamad Rami Radwan Jaber Chlorination of sucrose-6-esters
GB2469157B (en) 2009-03-30 2011-07-06 John Kerr Process for removing dimethylamine during sucralose production
GB2469158B (en) 2009-03-31 2011-09-28 Peter J Seaberg Base-assisted formation of tin-sucrose adducts
GB2471348B (en) 2009-06-22 2011-12-14 Tate & Lyle Technology Ltd A method for producing sucralose-6-acylate
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
GB2474311B (en) * 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
GB201110520D0 (en) 2011-05-10 2011-08-03 Tate & Lyle Technology Ltd Extraction of carboxylic acids with tin compounds
GB2539112B (en) 2013-12-16 2020-11-04 Tate & Lyle Tech Ltd Chlorination of sucrose-6-esters
WO2016020635A1 (en) 2014-08-08 2016-02-11 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
GB2536480B (en) 2015-03-17 2019-09-04 Tate & Lyle Tech Ltd DMF Distillation
GB2551591B (en) 2016-06-23 2019-08-07 Tate & Lyle Tech Ltd Liquid-liquid extraction of DMF
WO2024082158A1 (zh) * 2022-10-19 2024-04-25 安徽金禾实业股份有限公司 一种利用三氯蔗糖-6-乙酸酯结晶母液制备三氯蔗糖粗品的方法
CN115819478A (zh) * 2022-11-17 2023-03-21 安徽金禾实业股份有限公司 一种三氯蔗糖粗品母液提纯后制取三氯蔗糖的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3165986D1 (en) * 1980-07-08 1984-10-18 Tate & Lyle Plc Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs)
GB8617222D0 (en) * 1986-07-15 1986-08-20 Tate & Lyle Plc Sweetener
US4950746A (en) * 1988-07-18 1990-08-21 Noramco, Inc. Process for synthesizing sucrose derivatives by regioselective reaction
GB8822673D0 (en) * 1988-09-27 1988-11-02 Tate & Lyle Plc Selective acylation of sugars
US4980463A (en) * 1989-07-18 1990-12-25 Noramco, Inc. Sucrose-6-ester chlorination
US5089608A (en) * 1990-03-23 1992-02-18 Mcneil-Ppc, Inc. Selective 6-acylation of sucrose mediated by cyclic adducts of dialkyltin oxides and diols
US5023329A (en) * 1990-04-23 1991-06-11 Noramco, Inc. Sucrose-6-ester production process
US5034551A (en) * 1990-04-23 1991-07-23 Noramco, Inc. Process for recovery of organotin esters from reaction mixtures containing the same and re-use of the recovered organotin compounds
US5136031A (en) * 1990-07-09 1992-08-04 Tate & Lyle Public Limited Company Chlorination of sugars
US5298611A (en) * 1993-03-12 1994-03-29 Mcneil-Ppc, Inc. Sucralose pentaester production
US5498709A (en) * 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
GB9517281D0 (en) * 1995-08-23 1995-10-25 Tate & Lyle Plc Solid sucralose
US6075139A (en) * 1996-07-24 2000-06-13 Iowa State University Research Foundation, Inc. Linear and cyclic sucrose reaction products, their preparation and their use
WO1998035974A1 (en) * 1997-02-13 1998-08-20 Mcneil-Ppc Inc. Chromatographic purification of chlorinated sucrose
US5900478A (en) * 1997-06-20 1999-05-04 Iowa State University Research Foundation, Inc. Activated mono-, di-, and polysaccharides reaction products thereof, their preparation and uses
GB0008392D0 (en) * 2000-04-05 2000-05-24 Unilever Plc Process for the production of a deodorant or antiperspirant product
KR100854528B1 (ko) * 2000-11-17 2008-08-26 테이트 앤드 라일 퍼블릭 리미티드 컴파니 개선된 수크랄로즈 조성물 및 이의 제조방법
US6890581B2 (en) * 2002-04-05 2005-05-10 Tate & Lyle Public Limited Company Methods for buffer stabilized aqueous deacylation
US6984732B2 (en) * 2003-03-31 2006-01-10 Mcneil-Ppc, Inc. High-intensity sweetener composition and delivery of same

Also Published As

Publication number Publication date
KR20080016896A (ko) 2008-02-22
US20060276639A1 (en) 2006-12-07
EP1888609A1 (en) 2008-02-20
AU2005332295A1 (en) 2006-12-07
WO2006130169A1 (en) 2006-12-07
IL187818A0 (en) 2008-08-07
JP2008542370A (ja) 2008-11-27
EP1888609A4 (en) 2009-06-10
CA2610493A1 (en) 2006-12-07

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Legal Events

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B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: SOLICITA-SE A REGULARIZACAO DA PROCURACAO, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO EM SUA FORMA AUTENTICADA; OU SEGUNDO PARECER DA PROCURADORIA NO 074/93, DEVE CONSTAR UMA DECLARACAO DE VERACIDADE, A QUAL DEVE SER ASSINADA POR UMA PESSOA DEVIDAMENTE AUTORIZADA A REPRESENTAR O INTERESSADO, DEVENDO A MESMA CONSTAR NO INSTRUMENTO DE PROCURACAO, OU NO SEU SUBSTABELECIMENTO.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.